Bias in evaluating CNS complications following pertussis immunization.
Acta Paediatr Jpn. 1991 Aug;33(4):421-7. PMID: 1792899
Institute of Vaccinology and Virology, Hamburg, Germany.
Bias in the evaluation of CNS complications following pertussis immunization are the following: 1) Notifications of postimmunization adverse events, 2) Publications by vaccine producers on the frequency of adverse reactions, 3) Comparison of permanent brain damage after DPT and DT immunization, 4) Pro-immunization, 5) Immunization associated viral encephalitis, 6) Accuracy of statistics, 7) Personal. A review of these points indicates an underestimation of CNS complications after pertussis immunization.