Abstract Title:

Aplastic anemia following varicella vaccine.

Abstract Source:

Pediatr Infect Dis J. 2009 Aug;28(8):746-8. PMID: 19633522

Abstract Author(s):

Paola Angelini, Fotini Kavadas, Navneet Sharma, Susan E Richardson, Graham Tipples, Chaim Roifman, Yigal Dror, Yehuda Nofech-Mozes

Article Affiliation:

Division of Haematology and Oncology, Hospital for Sick Children, Toronto, Canada. [email protected]


Varicella zoster vaccine is a safe vaccine that is rarely associated with life-threatening complications. We describe an immunocompetent child who developed transient severe aplastic anemia concomitant with a typical clinical and laboratory-proven chickenpox syndrome 3 weeks after immunization. A causative association between the vaccine and the hematologic disease is possible, and pediatricians should be aware of this severe although rare adverse event.

Study Type : Human Study

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Sayer Ji
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