Varicella vaccine may be associated with aplastic anemia in children. - GreenMedInfo Summary
Aplastic anemia following varicella vaccine.
Pediatr Infect Dis J. 2009 Aug;28(8):746-8. PMID: 19633522
Division of Haematology and Oncology, Hospital for Sick Children, Toronto, Canada. [email protected]
Varicella zoster vaccine is a safe vaccine that is rarely associated with life-threatening complications. We describe an immunocompetent child who developed transient severe aplastic anemia concomitant with a typical clinical and laboratory-proven chickenpox syndrome 3 weeks after immunization. A causative association between the vaccine and the hematologic disease is possible, and pediatricians should be aware of this severe although rare adverse event.