Abstract Title:

Wogonin alleviates hyperglycemia through increased glucose entry into cells via AKT/GLUT4 pathway.

Abstract Source:

Curr Pharm Des. 2019 Jul 22. Epub 2019 Jul 22. PMID: 31333118

Abstract Author(s):

Shahzad Khan, Mohammad Amjad Kamal

Article Affiliation:

Shahzad Khan


Insulin resistance and type 2 Diabetes mellitus resulting in chronic hyperglycemia is a major health problem in the today modern world. Many drugs have been tested to control hyperglycemia which is believed to be main factor behind many of the diabetes related late term complications. Wogonin is a famous herbal medicine which has been shown to be effective in controlling diabetes and its complications. In our previous work we have shown that wogonin is beneficial in many ways in controlling diabetic cardiomyopathy. In this review, we have mainly explained wogonin anti-hyperglycemic property through AKT/GLUT4 pathway. Here we briefly discussed that wogonin increases Glut4 trafficking to plasma membrane which allow increased entry of glucose and thus alleviate hyperglycemia. Conclusion: Wogonin can be used as anti-diabetic and anti-hyperglycemic drug and works via AKT/GLUT4 pathway.

Study Type : In Vitro Study

Print Options

Key Research Topics

Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get Nature's Evidence-Based Pharmacy

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.

Download Now

500+ pages of Natural Medicine Alternatives and Information.

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2022 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.