Abstract Title:

Bioactive pyranoxanthones from the roots of Calophyllum blancoi.

Abstract Source:

Chem Pharm Bull (Tokyo). 2005 Feb ;53(2):244-7. PMID: 15684529

Abstract Author(s):

Ya-Ching Shen, Li-Tang Wang, Ashraf Taha Khalil, Lien Chai Chiang, Pei-Wen Cheng

Article Affiliation:

Ya-Ching Shen


Phytochemical investigation of the roots of Calophyllum blancoi growing in Taiwan resulted in the isolation of three new pyranoxanthones, blancoxanthone (1), acetyl blancoxanthone (2) and 3-hydroxyblancoxanthone (3), in addition to two known pyranoxanthones, pyranojacaeubin (4) and caloxanthone (5). Structural characterization of the isolated compounds was determined by spectral analyses especially 2-D NMR. Biological study of the isolated xanthones revealed that blancoxanthone (1) exhibited significant anti-coronavirus activity.

Study Type : In Vitro Study

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