Abstract Title:

Zolpidem-induced amnesia and somnambulism: rare occurrences?

Abstract Source:

Eur Neuropsychopharmacol. 2009 Jan;19(1):74-6. Epub 2008 Sep 25. PMID: 18819779

Abstract Author(s):

Jui-Hsiu Tsai, Pinchen Yang, Cheng-Chung Chen, Weilum Chung, Tze-Chun Tang, Shing-Yaw Wang, Jong-Kang Liu

Article Affiliation:

Department of Psychiatry, Kaohsiung Municipal Hsiao-Kang Hospital, Taiwan, ROC.


Zolpidem, a non-benzodiazepine hypnotic of the imidazopyridine class, is very effective in treating insomnia with previous claims of little adverse effects. However, zolpidem-induced somnambulism and amnesic sleep-related behavioral problems were begun to be reported in literature but no systemic investigation has been undertaken in non-Western cultures. In our current retrospective survey, 5.1% (13 out of 255) of Taiwanese patients reported change in sleep-related behavior as adverse effects. This serves as a reminder for clinicians to inquire regarding any unusual behavior of parasomniac activities when prescribing zolpidem.

Study Type : Commentary
Additional Links
Adverse Pharmacological Actions : Amnesiac : CK(14) : AC(5)

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