Latest GMI Study Abstracts

Latest GMI Study Abstracts

Bromelain Ameliorates Atherosclerosis.

Article Published Date : Dec 28, 2022
Study Type : Animal Study
Additional Links
Substances : Bromelain : CK(230) : AC(78)
Diseases : Atherosclerosis : CK(1390) : AC(487)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856), Hypolipidemic : CK(5358) : AC(1221)

Diosmin mitigates dexamethasone-induced osteoporosis.

Article Published Date : Apr 30, 2023
Study Type : Animal Study
Additional Links
Substances : Diosmin : CK(303) : AC(87)
Diseases : Osteoporosis : CK(2025) : AC(512), Oxidative Stress : CK(9437) : AC(3550)
Pharmacological Actions : Anti-Apoptotic : CK(2905) : AC(1672), Antioxidants : CK(21528) : AC(8856)
Problem Substances : Dexamethasone : CK(71) : AC(16)

Selective PPARγ modulator diosmin improves insulin sensitivity and promotes browning of white fat.

Article Published Date : Mar 31, 2023
Study Type : Animal Study
Additional Links
Substances : Diosmin : CK(303) : AC(87)
Diseases : Fatty Liver : CK(2522) : AC(701), Inflammation : CK(9572) : AC(3089), Insulin Resistance : CK(3522) : AC(792), Obesity : CK(6879) : AC(1686)
Additional Keywords : Anti-Obesity Agents : CK(2925) : AC(774)

Appraisal of the pre-emptive effect of lactoferrin against chromium-induced testicular toxicity.

Article Published Date : Mar 05, 2023
Study Type : Animal Study
Additional Links
Substances : Lactoferrin : CK(500) : AC(195)
Diseases : Testicular Injury: Chemical/Metal Induced : CK(340) : AC(174)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856), Interleukin-6 Downregulation : CK(5029) : AC(1994), Nrf2 activation : CK(1584) : AC(916), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(6736) : AC(2815)

Lactoferrin suppresses the progression of colon cancer under hyperglycemia.

Article Published Date : Feb 27, 2023
Study Type : In Vitro Study
Additional Links
Substances : Lactoferrin : CK(500) : AC(195)
Diseases : Colon Cancer : CK(1493) : AC(954), Diabetes Mellitus: Type 2 : CK(8552) : AC(1714)
Pharmacological Actions : Antiproliferative : CK(6801) : AC(5032)

Molecular mechanisms of inhibitory effects of bovine lactoferrin on invasion of oral squamous cell carcinoma.

Article Published Date : Feb 06, 2023
Study Type : In Vitro Study
Additional Links
Substances : Lactoferrin : CK(500) : AC(195)
Diseases : Oral Cancer : CK(510) : AC(245), Squamous cell carcinoma : CK(427) : AC(218)
Pharmacological Actions : Anti-metastatic : CK(1972) : AC(1481), Antiproliferative : CK(6801) : AC(5032), Matrix metalloproteinase-1 (MMP-1) inhibitor : CK(99) : AC(59), Matrix metalloproteinase-3 (MMP-3) inhibitor : CK(169) : AC(68)

Lactoferrin alleviates cyclophosphamide induced-nephropathy.

Article Published Date : Apr 14, 2023
Study Type : Animal Study
Additional Links
Substances : Lactoferrin : CK(500) : AC(195)
Diseases : Chemotherapy-Induced Toxicity: Cyclophosphamide : CK(267) : AC(124), Nephropathy : CK(239) : AC(58), Oxidative Stress : CK(9437) : AC(3550)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856), NF-kappaB Inhibitor : CK(3536) : AC(2098), Nrf2 activation : CK(1584) : AC(916), Renoprotective : CK(2404) : AC(1075)

Lactoferrin attenuates intestinal barrier dysfunction and inflammation.

Article Published Date : Oct 31, 2022
Study Type : Animal Study
Additional Links
Substances : Lactoferrin : CK(500) : AC(195)
Diseases : Inflammation : CK(9572) : AC(3089)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Gastrointestinal Agents : CK(3145) : AC(843)

These findings demonstrate the associations between habitual intakes of sugar-sweetened beverages and several metabolic markers relevant to noncommunicable diseases.

Article Published Date : Jan 31, 2023
Study Type : Human Study
Additional Links
Diseases : High Sugar Diet : CK(313) : AC(80), Obesity : CK(6879) : AC(1686)
Problem Substances : Sugar Sweetened Beverages : CK(989) : AC(104)

The evidence reviewed supports a significant association between shorter sleep duration and higher SSBs intake in both children and adults.

Article Published Date : Mar 31, 2023
Study Type : Meta Analysis, Review
Additional Links
Diseases : High Sugar Diet : CK(313) : AC(80), Sleep Disorders : CK(1209) : AC(158)
Additional Keywords : Increased Risk : CK(6996) : AC(896)
Problem Substances : Sugar Sweetened Beverages : CK(989) : AC(104)

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