Latest GMI Study Abstracts

Latest GMI Study Abstracts

Tangeretin attenuates metabolic disorders and fatty liver induced by HFD.

Article Published Date : Mar 17, 2025
Study Type : Animal Study
Additional Links
Substances : Tangeretin : CK(206) : AC(114)
Diseases : High Fat Diet : CK(2128) : AC(1023), Nonalcoholic fatty liver disease (NAFLD) : CK(3713) : AC(1041)
Pharmacological Actions : Hepatoprotective : CK(9580) : AC(4059)

Tangeretin modulates gut microbiota metabolism and macrophage immunity following fecal microbiota transplantation in obesity.

Article Published Date : Mar 31, 2025
Study Type : Animal Study
Additional Links
Substances : Tangeretin : CK(206) : AC(114)
Diseases : Obesity : CK(11454) : AC(2776)
Therapeutic Actions : Microbiota Transfer Therapy : CK(227) : AC(67)
Pharmacological Actions : Gastrointestinal Agents : CK(8229) : AC(2489)

Tangeretin alleviates myocardial ischemia-reperfusion injury by inhibiting ferroptosis.

Article Published Date : Jun 04, 2025
Study Type : In Vitro Study
Additional Links
Substances : Tangeretin : CK(206) : AC(114)
Diseases : Lipid Peroxidation : CK(2138) : AC(853), Myocardial Ischemia : CK(1034) : AC(480)
Pharmacological Actions : Antioxidants : CK(36633) : AC(15372), Cardioprotective : CK(9869) : AC(3101)

Tangeretin protects against Aβ1-42-induced toxicity and exploring mitochondria-lysosome interactions in HT22 cells.

Article Published Date : May 04, 2025
Study Type : In Vitro Study
Additional Links
Substances : Tangeretin : CK(206) : AC(114)
Diseases : Alzheimer's Disease : CK(5601) : AC(2341)
Pharmacological Actions : Anti-Apoptotic : CK(6048) : AC(3422), Neuroprotective Agents : CK(21412) : AC(8494)

These findings provide a scientific basis for the potential use of tangeretin as a prebiotic to regulate intestinal microbiota.

Article Published Date : Dec 31, 2024
Study Type : Animal Study
Additional Links
Substances : Tangeretin : CK(206) : AC(114)
Diseases : Colitis : CK(1657) : AC(788), Diarrhea: Antibiotic-Associated : CK(233) : AC(32)
Pharmacological Actions : Gastrointestinal Agents : CK(8229) : AC(2489)

These findings highlight tangeretin's potential as a promising therapeutic candidate for memory-related disorders.

Article Published Date : Apr 30, 2025
Study Type : Animal Study
Additional Links
Substances : Tangeretin : CK(206) : AC(114)
Diseases : Memory Disorders : CK(2594) : AC(679)
Pharmacological Actions : Neuroprotective Agents : CK(21412) : AC(8494)

Tangeretin in the treatment of pulmonary fibrosis: Current advances and future perspectives.

Article Published Date : Dec 31, 2023
Study Type : Review
Additional Links
Substances : Tangeretin : CK(206) : AC(114)
Diseases : Pulmonary Fibrosis : CK(410) : AC(169)
Pharmacological Actions : Anti-Fibrotic : CK(2409) : AC(1144), Anti-Inflammatory Agents : CK(42487) : AC(16977), Antioxidants : CK(36633) : AC(15372)

Tangeretin suppresses RANKL-induced osteoclastogenesis and alleviates postmenopausal osteoporosis.

Article Published Date : Nov 30, 2025
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Tangeretin : CK(206) : AC(114)
Diseases : Osteoporosis : CK(2896) : AC(806)
Pharmacological Actions : Osteoprotective : CK(2200) : AC(746)

Nrf2-activated mitophagy and ferroptosis suppression synergistically mediate tangeretin's protection against hepatic ischemia-reperfusion injury.

Article Published Date : Aug 31, 2025
Study Type : Animal Study
Additional Links
Diseases : Liver Injury: Ischemia/reperfusion : CK(186) : AC(102)
Pharmacological Actions : Antioxidants : CK(36633) : AC(15372), Hepatoprotective : CK(9580) : AC(4059), Nrf2 activation : CK(3356) : AC(1913)

Tangeretin protects the kidney from ischemia-reperfusion injury.

Article Published Date : Oct 09, 2025
Study Type : Animal Study
Additional Links
Substances : Tangeretin : CK(206) : AC(114)
Diseases : Inflammation : CK(16959) : AC(5806), Ischemia : CK(648) : AC(337)
Pharmacological Actions : Anti-Apoptotic : CK(6048) : AC(3422), Anti-Inflammatory Agents : CK(42487) : AC(16977), NF-kappaB Inhibitor : CK(6344) : AC(3676)

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