Latest GMI Study Abstracts

Latest GMI Study Abstracts

These findings suggest that MLE and CGA effectively alleviate renal fibrosis.

Article Published Date : Dec 03, 2025
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid : CK(451) : AC(201), Mulberry : CK(585) : AC(300)
Diseases : Kidney Fibrosis : CK(284) : AC(160)
Pharmacological Actions : Anti-Fibrotic : CK(2566) : AC(1219), Renoprotective : CK(4944) : AC(2149)
Additional Keywords : Plant Extracts : CK(19783) : AC(7256)

Morusin suppresses the stemness characteristics of gastric cancer cells induced by hypoxic microenvironment.

Article Published Date : Mar 31, 2024
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids : CK(5535) : AC(2653), Mulberry : CK(585) : AC(300)
Diseases : Gastric Cancer : CK(1740) : AC(804)
Pharmacological Actions : Antiproliferative : CK(11104) : AC(8317)

Morusin inhibits breast cancer-induced osteolysis by decreasing phosphatidylinositol 3-kinase (PI3K)-mTOR signalling.

Article Published Date : Apr 30, 2024
Study Type : Animal Study
Additional Links
Substances : Flavonoids : CK(5535) : AC(2653), Mulberry : CK(585) : AC(300)
Diseases : Breast Cancer : CK(8563) : AC(3201)
Pharmacological Actions : Anti-metastatic : CK(3105) : AC(2360), Antiproliferative : CK(11104) : AC(8317)

Morusin, a novel inhibitor of ACLY, induces mitochondrial apoptosis in hepatocellular carcinoma cells through ROS-mediated mitophagy.

Article Published Date : Oct 31, 2024
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids : CK(5535) : AC(2653), Mulberry : CK(585) : AC(300)
Diseases : Liver Cancer : CK(3345) : AC(1783)
Pharmacological Actions : Apoptotic : CK(10518) : AC(8130)

Morusin regulates the migration of M2 macrophages and GBM cells through the CCL4-CCR5 axis.

Article Published Date : Feb 05, 2025
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids : CK(5535) : AC(2653), Mulberry : CK(585) : AC(300)
Diseases : Glioblastoma : CK(763) : AC(433)
Pharmacological Actions : Chemotherapeutic : CK(4561) : AC(1707)
Additional Keywords : Tumor Microenvironment : CK(192) : AC(140)

Morusin has a reversing effect on the EMT of gallbladder cancer cells by modulating STAT3/HIF-1α signaling.

Article Published Date : Dec 31, 2024
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Flavonoids : CK(5535) : AC(2653), Mulberry : CK(585) : AC(300)
Diseases : Gallbladder Cancer : CK(123) : AC(42)
Pharmacological Actions : Anti-metastatic : CK(3105) : AC(2360), Antineoplastic Agents : CK(2510) : AC(1686), Antiproliferative : CK(11104) : AC(8317)

Morusin suppresses pancreatic cancer cell proliferation and migration.

Article Published Date : Jun 22, 2025
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids : CK(5535) : AC(2653), Mulberry : CK(585) : AC(300)
Diseases : Pancreatic Cancer : CK(1605) : AC(605)
Pharmacological Actions : Antiproliferative : CK(11104) : AC(8317), Apoptotic : CK(10518) : AC(8130), NF-kappaB Inhibitor : CK(6610) : AC(3839)

Morusin attenuates LPS-induced inflammation and oxidative stress in lung epithelial cells by inhibiting NLRP3 inflammasome activation.

Article Published Date : Dec 31, 2024
Study Type : Animal Study
Additional Links
Substances : Flavonoids : CK(5535) : AC(2653)
Diseases : Inflammation : CK(17298) : AC(5965), Lipopolysaccharide-Induced Toxicity : CK(3559) : AC(2075), Lung Injury: Acute : CK(560) : AC(268), Oxidative Stress : CK(16515) : AC(6515)
Pharmacological Actions : Anti-Apoptotic : CK(6278) : AC(3556), Anti-Inflammatory Agents : CK(43670) : AC(17510), Interleukin-1 beta downregulation : CK(6783) : AC(3284), Interleukin-6 Downregulation : CK(10260) : AC(3990), NF-kappaB Inhibitor : CK(6610) : AC(3839), Postaglandin PGE2 downregulation : CK(406) : AC(210)

Morusin reverses paclitaxel resistance by inhibiting the stem cell-like properties of non-small cell lung cancer in a β-catenin-dependent manner.

Article Published Date : Sep 30, 2025
Study Type : Animal Study
Additional Links
Substances : Flavonoids : CK(5535) : AC(2653), Mulberry : CK(585) : AC(300)
Diseases : Cancers: Drug Resistant : CK(1015) : AC(732), Carcinoma: Non-Small-Cell Lung : CK(806) : AC(487), Lung Cancer : CK(3253) : AC(1546)
Pharmacological Actions : Apoptotic : CK(10518) : AC(8130), Chemosensitizer : CK(1772) : AC(1353)
Additional Keywords : Chemothapeutic Synergy: Paclitaxel : CK(178) : AC(132)

These findings highlight morusin's novel mechanistic advantage over MAS and support its potential as a translational therapy for pediatric post-infectious cough.

Article Published Date : Dec 31, 2024
Study Type : Animal Study
Additional Links
Substances : Flavonoids : CK(5535) : AC(2653), Mulberry : CK(585) : AC(300)
Diseases : Cough : CK(78) : AC(22)
Pharmacological Actions : Anti-Inflammatory Agents : CK(43670) : AC(17510), Antitussive Agents : CK(94) : AC(22)
Additional Keywords : Lung-gut axis, Superiority of Natural Substances versus Drugs : CK(1952) : AC(410)

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