Latest GMI Study Abstracts

Latest GMI Study Abstracts

Exploring the anticancer mechanisms of Dendrobium officinale polysaccharides in colorectal cancer.

Article Published Date : Jan 31, 2026
Study Type : In Vitro Study
Additional Links
Substances : Orchid : CK(108) : AC(83)
Diseases : Colorectal Cancer : CK(5096) : AC(2406)
Pharmacological Actions : Antiproliferative : CK(10807) : AC(8097), Apoptotic : CK(10227) : AC(7916)
Additional Keywords : Polysaccharides : CK(1470) : AC(829)

Dendrobium chrysanthum ethanolic extract induces apoptosis via p53 up-regulation in HeLa cells and inhibits tumor progression in mice.

Article Published Date : May 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Orchid : CK(123) : AC(83)
Diseases : Cervical Cancer : CK(1024) : AC(627), Lymphoma : CK(440) : AC(175)
Pharmacological Actions : Apoptotic : CK(10231) : AC(7919), Cell cycle arrest : CK(2235) : AC(1813), Tumor Suppressor Protein p53 Upregulation : CK(802) : AC(582)
Additional Keywords : Phytotherapy : CK(4085) : AC(1068), Plant Extracts : CK(19445) : AC(7121)

Bibenzyl and naphthalene derivatives from Dendrobium chrysanthum and their anti-hepatic-steatosis activities.

Article Published Date : Mar 31, 2024
Study Type : In Vitro Study
Additional Links
Substances : Orchid : CK(108) : AC(83)
Diseases : Liver Steatosis : CK(211) : AC(92)
Pharmacological Actions : Hepatoprotective : CK(9641) : AC(4090)

Study on differences in structure and anti-inflammatory activity of polysaccharides in five species of Dendrobium.

Article Published Date : Apr 23, 2025
Study Type : In Vitro Study
Additional Links
Substances : Orchid : CK(108) : AC(83)
Pharmacological Actions : Anti-Inflammatory Agents : CK(42929) : AC(17163)
Additional Keywords : Polysaccharides : CK(1470) : AC(829)

Dendrobium nobile Lindl. alkaloids ameliorate Aβ25-35-induced synaptic deficits.

Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Orchid : CK(108) : AC(83)
Diseases : Alzheimer's Disease : CK(5614) : AC(2349)
Pharmacological Actions : Neuroprotective Agents : CK(21512) : AC(8542)

Dendrobium nobile Lindl alkaloid and metformin ameliorate cognitive dysfunction.

Article Published Date : Aug 14, 2020
Study Type : In Vitro Study
Additional Links
Substances : Orchid : CK(123) : AC(83)
Diseases : Aging: Brain : CK(1144) : AC(274), Alzheimer's Disease : CK(5614) : AC(2349)
Pharmacological Actions : Neuroprotective Agents : CK(21512) : AC(8542)
Additional Keywords : Drug: Metformin : CK(231) : AC(40), Natural Substance/Drug Synergy : CK(1653) : AC(765), Plant Extracts : CK(19445) : AC(7121)

Protective effects of Dendrobium nobile Lindl. alkaloids in a novel mouse model of Alzheimer's disease with chronic cerebral hypoperfusion.

Article Published Date : Jan 31, 2026
Study Type : In Vitro Study
Additional Links
Substances : Orchid : CK(108) : AC(83)
Diseases : Alzheimer's Disease : CK(5614) : AC(2349)
Pharmacological Actions : Neuroprotective Agents : CK(21512) : AC(8542)

Erianin isolated from Dendrobium huoshanense alleviated neuroinflammation in MPTP-induced Parkinson's disease model.

Article Published Date : Apr 08, 2025
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Orchid : CK(123) : AC(83)
Diseases : Oxidative Stress : CK(16166) : AC(6363), Parkinson's Disease : CK(3218) : AC(1200)
Pharmacological Actions : Anti-Inflammatory Agents : CK(42929) : AC(17163), Neuroprotective Agents : CK(21512) : AC(8542), NF-kappaB Inhibitor : CK(6444) : AC(3738)

Dendrobium huoshanense attenuates Parkinsonian neurodegeneration via dual antioxidant and anti-inflammatory pathways.

Article Published Date : Mar 24, 2026
Study Type : Animal Study
Additional Links
Substances : Orchid : CK(123) : AC(83)
Diseases : Oxidative Stress : CK(16166) : AC(6363), Parkinson's Disease : CK(3218) : AC(1200)
Pharmacological Actions : Anti-Inflammatory Agents : CK(42929) : AC(17163), Antioxidants : CK(36936) : AC(15504), Neuroprotective Agents : CK(21512) : AC(8542), NF-kappaB Inhibitor : CK(6444) : AC(3738)
Additional Keywords : Plant Extracts : CK(19445) : AC(7121)

The mechanism of Dendrobium officinale polysaccharides in alleviating osteoporosis.

Article Published Date : Jan 13, 2026
Study Type : Animal Study
Additional Links
Substances : Orchid : CK(123) : AC(83)
Diseases : Osteoporosis : CK(2913) : AC(812)
Pharmacological Actions : Gastrointestinal Agents : CK(8254) : AC(2502), Wnt/β-catenin signaling pathway modulation : CK(350) : AC(240)
Additional Keywords : Plant Extracts : CK(19445) : AC(7121), Polysaccharides : CK(1470) : AC(829)

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