Latest GMI Study Abstracts

Latest GMI Study Abstracts

Flavonoid-rich extracts of Nelumbo nucifera leaves alleviate obesity in HFD-fed mice via microbiota-dependent modulation of brown fat thermogenesis.

Article Published Date : Jan 09, 2026
Study Type : Animal Study
Additional Links
Substances : Flavonoids : CK(5535) : AC(2653), Lotus : CK(454) : AC(291)
Diseases : Obesity : CK(11610) : AC(2816)
Additional Keywords : Anti-Obesity Agents : CK(5518) : AC(1405), Plant Extracts : CK(19783) : AC(7256)

These findings suggest that lotus alkaloids are promising candidates for the prevention and treatment of neurodegenerative diseases.

Article Published Date : Aug 25, 2025
Study Type : Review
Additional Links
Substances : Lotus : CK(454) : AC(291)
Diseases : Alzheimer's Disease : CK(5678) : AC(2383), Neurodegenerative Diseases : CK(13800) : AC(4587), Parkinson's Disease : CK(3232) : AC(1209)
Pharmacological Actions : Anti-Inflammatory Agents : CK(43668) : AC(17509), Antioxidants : CK(37413) : AC(15719), Neuroprotective Agents : CK(21754) : AC(8657)

These findings highlight the potential of lotus seedpod as a natural source of hypolipidemic actives.

Article Published Date : Apr 30, 2026
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Lotus : CK(454) : AC(291), Polyphenols : CK(2958) : AC(1096)
Diseases : Obesity : CK(11610) : AC(2816)
Additional Keywords : Plant Extracts : CK(19783) : AC(7256)

Hyperoside alleviates Helicobacter pylori-induced gastric epithelial cell injury.

Article Published Date : Feb 28, 2025
Study Type : Animal Study
Additional Links
Substances : Flavonoids : CK(5535) : AC(2653)
Diseases : Helicobacter Pylori Infection : CK(1234) : AC(288), Oxidative Stress : CK(16515) : AC(6515)
Pharmacological Actions : Anti-Apoptotic : CK(6278) : AC(3556), Gastrointestinal Agents : CK(8375) : AC(2556), Heme oxygenase-1 up-regulation : CK(1492) : AC(865), Nrf2 activation : CK(3467) : AC(1975)

Anticancer therapeutic potential of genus Diospyros: From phytochemistry to clinical applications-A review.

Article Published Date : Sep 30, 2024
Study Type : Review
Additional Links
Substances : Persimmon : CK(252) : AC(121)
Diseases : Cancers: All : CK(38021) : AC(15295)
Pharmacological Actions : Antiproliferative : CK(11104) : AC(8317), Apoptotic : CK(10518) : AC(8130)

Diospyros kaki fruit extract produces antiarthritic and antinociceptive effects in rats with complete Freund's adjuvant-induced arthritis.

Article Published Date : Sep 30, 2024
Study Type : Animal Study
Additional Links
Substances : Persimmon : CK(252) : AC(121)
Diseases : Arthritis : CK(6279) : AC(1644)
Pharmacological Actions : Anti-Inflammatory Agents : CK(43668) : AC(17509), Antinoceceptive : CK(997) : AC(308), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(12806) : AC(5272)

Diospyros kaki Thunb.) exhibits anticancer activity by inducing mitochondrial dysfunction in colorectal cancer cells.

Article Published Date : Oct 30, 2024
Study Type : In Vitro Study
Additional Links
Substances : Persimmon : CK(252) : AC(121)
Diseases : Colorectal Cancer : CK(5144) : AC(2441), Oxidative Stress : CK(16515) : AC(6515)
Pharmacological Actions : Antiproliferative : CK(11104) : AC(8317), Apoptotic : CK(10518) : AC(8130)
Additional Keywords : Plant Extracts : CK(19783) : AC(7256)

Persimmon (Diospyros kaki L.) leaves accelerates skin tissue regeneration in excisional wound model: possible molecular mechanisms.

Article Published Date : Jan 23, 2025
Study Type : Animal Study
Additional Links
Substances : Persimmon : CK(252) : AC(121)
Diseases : Wound Healing : CK(4805) : AC(1506)
Pharmacological Actions : Anti-Inflammatory Agents : CK(43668) : AC(17509), Interleukin-6 Downregulation : CK(10260) : AC(3990), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(12806) : AC(5272)
Additional Keywords : Plant Extracts : CK(19783) : AC(7256)

Diospyros lotus leaf extract and its main component, myricitrin, inhibit both histamine‑dependent and histamine‑independent itching.

Article Published Date : May 31, 2025
Study Type : In Vitro Study
Additional Links
Substances : Persimmon : CK(252) : AC(121)
Diseases : Itching : CK(85) : AC(15)
Pharmacological Actions : Antipruritics : CK(17) : AC(6)

The modulatory effects of persimmon leaf extract on sleep-related neurotransmitters and its potential hypnotic effects.

Article Published Date : May 31, 2025
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Persimmon : CK(252) : AC(121)
Diseases : Insomnia : CK(1350) : AC(172)
Pharmacological Actions : Hypnotics and Sedatives : CK(150) : AC(62)
Additional Keywords : Plant Extracts : CK(19783) : AC(7256)

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