Latest GMI Study Abstracts

Latest GMI Study Abstracts

Hyperoside attenuates dextran sulfate sodium-induced colitis.

Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Flavonoids : CK(2352) : AC(870)
Diseases : Colitis : CK(840) : AC(406)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856), Cyclooxygenase 2 Inhibitors : CK(1589) : AC(926), Interleukin-6 Downregulation : CK(5029) : AC(1994), Nrf2 activation : CK(1584) : AC(916), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(6736) : AC(2815)

Hyperoside alleviates adriamycin-induced podocyte injury via inhibiting mitochondrial fission.

Article Published Date : Oct 23, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Flavonoids : CK(2352) : AC(870)
Diseases : Chemotherapy-Induced Toxicity: Doxorubicin : CK(457) : AC(236)
Pharmacological Actions : Chemoprotective Agents : CK(2322) : AC(906)

Hyperoside protects human kidney‑2 cells against oxidative damage induced by oxalic acid.

Article Published Date : Jun 30, 2018
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids : CK(2352) : AC(870)
Diseases : Kidney Damage: Chemically-Induced : CK(25) : AC(13), Oxidative Stress : CK(9437) : AC(3550)
Pharmacological Actions : Antioxidants : CK(21528) : AC(8856), Heme oxygenase-1 up-regulation : CK(624) : AC(373), Nrf2 activation : CK(1584) : AC(916), Renoprotective : CK(2404) : AC(1075)

Hyperoside suppresses lipopolysaccharide-induced inflammation and apoptosis in human umbilical vein endothelial cells.

Article Published Date : Mar 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids : CK(2352) : AC(870)
Diseases : Inflammation : CK(9572) : AC(3089), Lipopolysaccharide-Induced Toxicity : CK(1764) : AC(1073)
Pharmacological Actions : Anti-Apoptotic : CK(2905) : AC(1672), Anti-Inflammatory Agents : CK(20859) : AC(8334), Interleukin-1 beta downregulation : CK(3041) : AC(1567), Interleukin-6 upregulation : CK(32) : AC(11), NF-kappaB Inhibitor : CK(3536) : AC(2098), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(6736) : AC(2815)

Hyperoside suppresses tumor necrosis factor α-mediated vascular inflammatory responses.

Article Published Date : Sep 30, 2018
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids : CK(2352) : AC(870)
Diseases : Inflammation : CK(9572) : AC(3089)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), NF-kappaB Inhibitor : CK(3536) : AC(2098), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(6736) : AC(2815)

Perilla leaf extract inhibits SARS-CoV-2 via direct virus inactivation.

Article Published Date : Jan 27, 2021
Study Type : In Vitro Study
Additional Links
Substances : Perilla : CK(89) : AC(46)
Diseases : Coronavirus Infection : CK(1230) : AC(410)
Pharmacological Actions : Antiviral Agents : CK(1957) : AC(1034)

Perilla leaf extract attenuates asthma airway inflammation by blocking the syk pathway.

Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Perilla : CK(89) : AC(46)
Diseases : Asthma : CK(2488) : AC(486)
Pharmacological Actions : Anti-Asthmatic Agents : CK(286) : AC(71), Anti-Inflammatory Agents : CK(20859) : AC(8334)

Perillaldehyde inhibition of cGAS reduces dsDNA-induced interferon response.

Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Perillaldehyde : CK(1) : AC(1)
Diseases : Autoimmune Diseases : CK(9797) : AC(1966)
Pharmacological Actions : Immunomodulatory : CK(4048) : AC(1475)

Perilla frutescens extracts enhance DNA repair response in UVB damaged HaCaT cells.

Article Published Date : Apr 11, 2021
Study Type : In Vitro Study
Additional Links
Substances : Perilla : CK(89) : AC(46)
Diseases : Aging Skin : CK(677) : AC(168), DNA damage : CK(1997) : AC(713), Oxidative Stress : CK(9437) : AC(3550), Ultraviolet Radiation Induced Damage : CK(461) : AC(215)
Pharmacological Actions : Antioxidants : CK(21528) : AC(8856)
Additional Keywords : Plant Extracts : CK(14140) : AC(5210)

Ameliorative impacts of Glycyrrhiza glabra root extract against nephrotoxicity induced by gentamicin in mice.

Article Published Date : Jun 30, 2021
Study Type : Animal Study
Additional Links
Substances : Licorice : CK(697) : AC(305)
Diseases : Chemotherapy-Induced Kidney Damage : CK(98) : AC(44), Chemotherapy-Induced Toxicity: Gentamicin : CK(146) : AC(75)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856), Chemoprotective Agents : CK(2322) : AC(906), Heme oxygenase-1 up-regulation : CK(624) : AC(373), Interleukin-1 beta downregulation : CK(3041) : AC(1567), Interleukin-6 Downregulation : CK(5029) : AC(1994), Nrf2 activation : CK(1584) : AC(916), Renoprotective : CK(2404) : AC(1075)

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