Latest GMI Study Abstracts

Latest GMI Study Abstracts

Anti-inflammatory, anti-apoptotic, and neuroprotective potentials of anethole in Parkinson's disease.

Article Published Date : Jul 31, 2023
Study Type : Animal Study
Additional Links
Substances : Flavonoids : CK(2352) : AC(870)
Diseases : Parkinson's Disease : CK(1838) : AC(659)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856), Neuroprotective Agents : CK(10404) : AC(4396)

Synergistic effect of anethole and platinum drug cisplatin against oral cancer cell growth and migration.

Article Published Date : May 04, 2023
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids : CK(2352) : AC(870)
Diseases : Oral Cancer : CK(510) : AC(245)
Pharmacological Actions : Antiproliferative : CK(6801) : AC(5032)
Additional Keywords : Chemotherapeutic Synergy: Cisplatin : CK(290) : AC(232)

Anethole attenuates motor dysfunctions, striatal neuronal activity deficiency and blood brain barrier permeability.

Article Published Date : Dec 31, 2022
Study Type : Animal Study
Additional Links
Substances : Flavonoids : CK(2352) : AC(870)
Diseases : Parkinson's Disease : CK(1838) : AC(659)
Pharmacological Actions : Antioxidants : CK(21528) : AC(8856), Neuroprotective Agents : CK(10404) : AC(4396), Superoxide Dismutase Up-regulation : CK(1403) : AC(551)

Anethole mitigates H2O2-induced inflammation in HIG-82 synoviocytes.

Article Published Date : Nov 20, 2023
Study Type : In Vitro Study
Additional Links
Substances : Fennel : CK(232) : AC(50)
Diseases : Hydrogen Peroxide Induced Toxicity : CK(296) : AC(226), Inflammation : CK(9572) : AC(3089)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334)

Antibiofilm mechanism of peppermint essential oil to avert biofilm developed by foodborne and food spoilage pathogens on food contact surfaces.

Article Published Date : Aug 31, 2023
Study Type : In Vitro Study
Additional Links
Substances : Peppermint : CK(430) : AC(74)
Diseases : Foodborne Pathogens: Prevention/Food Preservation : CK(47) : AC(43), Listeria Infections : CK(76) : AC(64)
Pharmacological Actions : Anti-Bacterial Agents : CK(2894) : AC(1251)
Additional Keywords : Bacterial Infections: Resistance/Biofilm Formation

Palmitoylethanolamide and acetyl-L-carnitine act synergistically with duloxetine and pregabalin in fibromyalgia.

Article Published Date : May 31, 2023
Study Type : Human Study
Additional Links
Substances : Acetyl-l-carnitine : CK(211) : AC(36), Palmitoylethanolamide : CK(2) : AC(1)
Diseases : Fibromyalgia : CK(1103) : AC(132)
Pharmacological Actions : Analgesics : CK(3498) : AC(646)
Additional Keywords : Natural Substance/Drug Synergy : CK(957) : AC(485)

Palmitoylethanolamide counteracts high-fat diet-induced gut dysfunction by reprogramming microbiota composition and affecting tryptophan metabolism.

Article Published Date : Dec 31, 2022
Study Type : Animal Study
Additional Links
Substances : Palmitoylethanolamide : CK(2) : AC(1)
Diseases : High Fat Diet : CK(1267) : AC(602)
Pharmacological Actions : Gastrointestinal Agents : CK(3145) : AC(843), Gastroprotective : CK(955) : AC(388)

Efficacy of palmitoylethanolamide and luteolin association on post-covid olfactory dysfunction.

Article Published Date : Aug 02, 2023
Study Type : Meta Analysis, Review
Additional Links
Substances : Luteolin : CK(381) : AC(247), Palmitoylethanolamide : CK(2) : AC(1)
Diseases : Coronavirus Infection : CK(1230) : AC(410), Smell Disorders : CK(33) : AC(4)

N-palmitoylethanolamine modulates hippocampal neuroplasticity in rats with stress-induced depressive behavior phenotype.

Article Published Date : Oct 14, 2023
Study Type : Animal Study
Additional Links
Substances : Palmitoylethanolamide : CK(2) : AC(1)
Diseases : Depression : CK(6233) : AC(1096)
Pharmacological Actions : Antidepressive Agents : CK(4882) : AC(874), Neuroplasticity enhancement : CK(83) : AC(23)

Supplementation with PEALUT helped to improve all patient-reported symptoms, especially pain, anxiety and depression, fatigue, brain fog, anosmia and dysgeusia.

Article Published Date : Aug 23, 2023
Study Type : Human Study
Additional Links
Substances : Luteolin : CK(381) : AC(247), Palmitoylethanolamide : CK(2) : AC(1)
Diseases : Brain Inflammation : CK(1101) : AC(567), Coronavirus Disease : CK(309) : AC(106)
Pharmacological Actions : Anti-Anxiety Agents : CK(2913) : AC(487), Anti-Inflammatory Agents : CK(20859) : AC(8334), Antidepressive Agents : CK(4882) : AC(874)
Additional Keywords : Long Covid

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