Latest GMI Study Abstracts

Latest GMI Study Abstracts

Lactobacillus rhamnosus GG colonization in early life regulates gut-brain axis and relieves anxiety-like behavior in adulthood.

Article Published Date : Jan 18, 2022
Study Type : Animal Study
Additional Links
Substances : Lactobacillus rhamnosus GG : CK(466) : AC(98)
Diseases : Anxiety
Pharmacological Actions : Anti-Anxiety Agents : CK(2913) : AC(487)
Additional Keywords : Gut-brain Axis : CK(392) : AC(177)

Possible protective effects of CO Q10 against vincristine-induced peripheral neuropathy.

Article Published Date : Dec 22, 2021
Study Type : In Vitro Study
Additional Links
Substances : Coenzyme Q10 : CK(1858) : AC(315)
Diseases : Chemotherapy-Induced Toxicity: Peripheral Neuropathy : CK(178) : AC(27)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856)

Coenzyme Q10 protects against doxorubicin-induced cardiomyopathy.

Article Published Date : Dec 22, 2021
Study Type : Animal Study
Additional Links
Substances : Coenzyme Q10 : CK(1858) : AC(315)
Diseases : Chemotherapy-Induced Toxicity: Doxorubicin : CK(457) : AC(236)
Pharmacological Actions : Antioxidants : CK(21528) : AC(8856), Cardioprotective : CK(5377) : AC(1675), Chemoprotective Agents : CK(2322) : AC(906)

Potential protective effect of coenzyme Q10 on doxorubicin-induced neurotoxicity and behavioral disturbances.

Article Published Date : Jan 02, 2022
Study Type : Animal Study
Additional Links
Substances : Coenzyme Q10 : CK(1858) : AC(315)
Diseases : Chemotherapy-Induced Toxicity: Doxorubicin : CK(457) : AC(236)
Pharmacological Actions : Chemoprotective Agents : CK(2322) : AC(906), Neuroprotective Agents : CK(10404) : AC(4396)

The effect of coenzyme Q10 on liver injury induced by valproic acid and its antiepileptic activity.

Article Published Date : Jan 12, 2022
Study Type : Animal Study
Additional Links
Substances : Coenzyme Q10 : CK(1858) : AC(315)
Diseases : Chemically-Induced Liver Damage : CK(1565) : AC(721)
Pharmacological Actions : Anticonvulsants : CK(678) : AC(189)
Additional Keywords : Natural Substance/Drug Synergy : CK(957) : AC(485)

Krill oil combined with Bifidobacterium animalis subsp. lactis F1-7 alleviates the atherosclerosis.

Article Published Date : Oct 05, 2021
Study Type : Animal Study
Additional Links
Substances : Bifidobacterium animalis : CK(30) : AC(3), Krill : CK(203) : AC(52)
Diseases : Atherosclerosis : CK(1390) : AC(487)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334)

Diverse krill lipid fractions differentially reduce LPS-induced inflammatory markers.

Article Published Date : Nov 21, 2021
Study Type : In Vitro Study
Additional Links
Substances : Krill : CK(203) : AC(52)
Diseases : Lipopolysaccharide-Induced Toxicity : CK(1764) : AC(1073)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Interleukin-1 beta downregulation : CK(3041) : AC(1567), Interleukin-6 Downregulation : CK(5029) : AC(1994), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(6736) : AC(2815)

Krill oil inhibits NLRP3 inflammasome activation in the prevention of the pathological injuries of diabetic cardiomyopathy.

Article Published Date : Jan 14, 2022
Study Type : Animal Study
Additional Links
Substances : Krill : CK(203) : AC(52)
Diseases : Cardiomyopathy : CK(222) : AC(82), Diabetic Complications : CK(3199) : AC(1009)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Cardioprotective : CK(5377) : AC(1675)

Omega-3 fatty acid, carotenoid and vitamin E supplementation improves working memory in older adults.

Article Published Date : Dec 06, 2021
Study Type : Human Study
Additional Links
Substances : Carotenoids : CK(3269) : AC(832), Omega-3 Fatty Acids : CK(4672) : AC(633), Vitamin E : CK(2533) : AC(483)
Diseases : Aging: Brain : CK(720) : AC(189), Memory Disorders : CK(1067) : AC(339)
Pharmacological Actions : Neuroprotective Agents : CK(10404) : AC(4396)

GPR120 prevents colorectal adenocarcinoma progression by sustaining the mucosal barrier integrity.

Article Published Date : Jan 09, 2022
Study Type : Animal Study
Additional Links
Substances : Polyunsaturated Fatty Acids (PUFAs) : CK(366) : AC(67)
Diseases : Colorectal Cancer : CK(3666) : AC(1651)
Pharmacological Actions : Chemopreventive : CK(5374) : AC(1717), Gastrointestinal Agents : CK(3145) : AC(843)

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