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The alternative media is justifiably abuzz with a story about the CDC deleting a page on their website admitting that as many as 98 million Americans received polio vaccine contaminated with the cancer-linked monkey virus SV40, with the added twist that although they removed the page sometime after July 11th, a cached version is still available to view online.
Some of the details of the 'disappeared' page read as follows:
Cancer, Simian Virus 40 (SV40), and Polio Vaccine Fact Sheet
- SV40 is a virus found in some species of monkey.
- SV40 was discovered in 1960. Soon afterward, the virus was found in polio vaccine.
- More than 98 million Americans received one or more doses of polio vaccine from 1955 to 1963 when a proportion of vaccine was contaminated with SV40; it has been estimated that 10–30 million Americans could have received an SV40 contaminated dose of vaccine.
- SV40 virus has been found in certain types of cancer in humans, but it has not been determined that SV40 causes these cancers.
- The majority of scientific evidence suggests that SV40-contaminated vaccine did not cause cancer; however, some research results are conflicting and more studies are needed.
- Polio vaccines being used today do not contain SV40. All of the current evidence indicates that polio vaccines have been free of SV40 since 1963.
Plenty of folks are taking notice of the deletion of the page, and for good reason, as it was a relatively high-profile reference on sites like Wikipedia where it was cited three times [footnote 53] on the Polio Vaccines page, under the section "Contamination concerns," in the following paragraph:
SV40 was found to be present in stocks of the injected form of the polio vaccine (IPV) in use between 1955 to 1963.[53] It is not found in the OPV form.[53] Over 98 million Americans received one or more doses of polio vaccine between 1955 to 1963 when a proportion of vaccine was contaminated with SV40; it has been estimated that 10–30 million Americans may have received a dose of vaccine contaminated with SV40.[53] Later analysis suggested that vaccines produced by the former Soviet bloc countries until 1980, and used in the USSR, China, Japan, and several African countries, may have been contaminated; meaning hundreds of millions more may have been exposed to SV40.[58]
Now when you click the citations on Wikipedia taking you to the CDC's website you get the following message:
We can understand why the CDC would want to flush this information down the 'memory hole,' as any indication that vaccines actually cause disease, especially as terrible as cancer, is a public relations nightmare for an agency aggressively expanding its immunization schedule under the auspices of their bulletproof 'safety' and 'efficacy,' as well as looking for public support for legislation that would further limit and even ban vaccine exemptions.
But this "leak" is really only the tip of the iceberg. SV40, which stands for Simian Virus #40, is only one of a wide range of so-called "adventitious" viruses that continue to contaminate vaccine seed stock and substrate (cells used to grow vaccine), which include endogenous retroviruses such as mouse mammary tumor virus, and many which have yet to be identified. SV40 was after all the 40th simian virus identified, and this was 50 years ago. We can only imagine how many hidden disease vectors exist and have been identified by vaccinologists and virologists over the intervening years, but which never made it to the light of day.
Additionally, the information the CDC deleted from its website, is highly misleading. For example, the CDC says:
"SV40 virus has been found in certain types of cancer in humans, but it has not been determined that SV40 causes these cancers."
SV-40 has a well-known mechanism of carcinogenicity. This virus suppresses the transcriptional properties of the tumor-suppressing p53 protein in humans, a gene product that has been described as "the guardian of the genome" because of its critical role in preventing genome instability and cancer initiation.[1] When p53 is disabled, programmed cell death (apoptosis) and cell cycle arrest is rendered dysfunctional, leading to uncontrolled (immortalized) cell proliferation, and tumor formation. Animal research provides experimental confirmation for the tumor-forming properties of SV40,[2] which lends support to viewing the presence of SV40 in various human tumors as a causal connection and not a merely coincidental correlation.[3] [4] [5] [6] [7] [8] [9] [10] [11] [12]
Also, the CDC's claim that SV40 has not been proven "a cause" is disingenuous, as no cancer can be considered to be a result of a singular cause. SV40 is a well-known cofactor in the pathogenesis of some tumors,[13] [14] and therefore should not be dismissed or minimized to the point of being perceived irrelevant.
CDC: "All of the current evidence indicates that polio vaccines have been free of SV40 since 1963."
Not so. In 2005, the journal Cancer Research published a study titled, "Some oral poliovirus vaccines were contaminated with infectious SV40 after 1961."[15] The research for the study was prompted by the detection of SV40 in a wide range of human tumors,(3-12) leading the World Health Organization to issue a recommendation in 2000 to test polio vaccines produced after 1961. They found that vaccines from a major eastern European manufacturer (EEVM) contained infectious SV40 which were "produced from early 1960s to about 1978 and were used throughout the world." They used 3 different technical approaches (PCR, transfection, and direct infection of susceptible cell cultures) to confirm the presence of two separate infectious SV40 strains in EEVM.
The researchers expanded on this finding:
The EEVM samples that we tested were produced in 1966 and 1969; therefore, we show that SV40 contaminated some polio vaccines at least until that period. The EEVM vaccine samples we tested ( Table 1) were produced with the same seed virus that was used until 1978, apparently without any further purification to remove SV40. Therefore, it is possible that the EEVM vaccines may have remained SV40 contaminated until 1978 when a new seed was produced. We have no information about this seed virus or vaccines produced from it. Therefore, based on our data, we could not determine the exact time when EEVM vaccines became SV40 free but can suggest that it may have happened in the 1980s when EEVM switched to seed virus stocks provided by the WHO that we found to be free of SV40.
It should be noted that oral polio vaccines were discontinued in the US due to their well-known dangers in favor of the inactivated form. Vaccine-associated polio paralysis (VAPP) was, in fact, the predominant form of the polio paralysis in developed countries like the US since 1973.[16] This lead the Advisory Committee on Immunization Practices (ACIP) in 2000 to recommend altogether eliminating the live-virus oral polio vaccine (OPV), which is still used throughout the third world, despite the known risks. Is the oral polio vaccine in India or Afghanistan free of SV40 contamination? We do not know. But given the track record of contamination that haunts the entire history of vaccinology, it is possible that they still are – especially since the cell substrates used to produce these vaccines may still be contaminated with SV40 virus, and the fact that they have been linked to thousands of cases of paralysis.
Another important consideration conveniently omitted on the CDC fact sheet about SV40 is that the virus is somehow being passed down from generation to generation.
A 2012 Italian study found that 18% of healthy volunteers were found contaminated with SV40 viral fragments,[17] indicating that they were either: 1) exposed to SV40 virus through contemporary vaccines commonly believed to be "SV40-free." 2) exposed horizontally via transmission from an older generation carrying oral polio-vaccine derived SV40 vaccine. 3) passed down vertically from parent to child.
In any one of these scenarios the point is that far more than 98 million Americans are now contaminated with the virus, and those infected are likely expanding in number unchecked. The problem didn't end with the removal of the contaminated seed stock in the production of oral polio vaccines, or the use of inactivated forms that were developed later. This is one of the dark secrets of the unintended, adverse effects of vaccination that the CDC's most recent attempt to hide has actually brought directly into the daylight of public scrutiny.
For more research on the topic visit our page on Simian Virus 40 and our Vaccine Research page:
[1] ^ Read, A. P.; Strachan, T.. Human molecular genetics 2. New York: Wiley; 1999.ISBN 0-471-33061-2. Chapter 18: Cancer Genetics.
[2] M Carbone, R Stach, I Di Resta, H I Pass, P Rizzo. Simian virus 40 oncogenesis in hamsters.Dev Biol Stand. 1998 ;94:273-9. PMID: 9776247
[3] Regis A Vilchez, Claudia A Kozinetz, Amy S Arrington, Charles R Madden, Janet S Butel. Simian virus 40 in human cancers. Am J Med. 2003 Jun 1 ;114(8):675-84. PMID: 12798456
[4] Narayan Shivapurkar, Takao Takahashi, Jyotsna Reddy, Yingye Zheng, Victor Stastny, Robert Collins, Shinichi Toyooka, Makato Suzuki, Gunjan Parikh, Sheryl Asplund, Steven H Kroft, Charles Timmons, Robert W McKenna, Ziding Feng, Adi F Gazdar. Presence of simian virus 40 DNA sequences in human lymphoid and hematopoietic malignancies and their relationship to aberrant promoter methylation of multiple genes. Cancer Res. 2004 Jun 1;64(11):3757-60. PMID: 15172980
[5] Fernanda Martini, Alfredo Corallini, Veronica Balatti, Silvia Sabbioni, Cecilia Pancaldi, Mauro Tognon. Simian virus 40 in humans. Infect Agent Cancer. 2007 ;2:13. Epub 2007 Jul 9. PMID:17620119
[6] Regis A Vilchez, Claudia A Kozinetz, Amy S Arrington, Charles R Madden, Janet S Butel. Simian virus 40 in human cancers. Am J Med. 2003 Jun 1 ;114(8):675-84. PMID: 12798456
[7] P Rizzo, I Di Resta, R Stach, L Mutti, P Picci, W M Kast, H I Pass, M Carbone. Evidence for and implications of SV40-like sequences in human mesotheliomas and osteosarcomas. Dev Biol Stand. 1998 ;94:33-40. PMID: 9776223
[8] D S Schrump, I Waheed. Strategies to circumvent SV40 oncoprotein expression in malignant pleural mesotheliomas. Semin Cancer Biol. 2001 Feb;11(1):73-80. PMID:11243901
[9] Khaled Amara, Mounir Trimeche, Sonia Ziadi, Adnene Laatiri, Mohamed Hachana, Badreddine Sriha, Moncef Mokni, Sadok Korbi. Presence of simian virus 40 DNA sequences in diffuse large B-cell lymphomas in Tunisia correlates with aberrant promoter hypermethylation of multiple tumor suppressor genes. Int J Cancer. 2007 Dec 15;121(12):2693-702. PMID:17724719
[10] S G Fisher, L Weber, M Carbone. Cancer risk associated with simian virus 40 contaminated polio vaccine. Anticancer Res. 1999 May-Jun;19(3B):2173-80. PMID: 10472327
[11] Kristin K Deeb, Aleksandra M Michalowska, Cheol-Yong Yoon, Scott M Krummey, Mark J Hoenerhoff, Claudine Kavanaugh, Ming-Chung Li, Francesco J Demayo, Ilona Linnoila, Chu-Xia Deng, Eva Y-H P Lee, Daniel Medina, Joanna H Shih, Jeffrey E Green. Identification of an integrated SV40 T/t-antigen cancer signature in aggressive human breast, prostate, and lung carcinomas with poor prognosis. Cancer Res. 2007 Sep 1;67(17):8065-80. PMID:17804718
[12] Giuseppe Barbanti-Brodano, Silvia Sabbioni, Fernanda Martini, Massimo Negrini, Alfredo Corallini, Mauro Tognon. Simian virus 40 infection in humans and association with human diseases: results and hypotheses. Virology. 2004 Jan 5;318(1):1-9. PMID: 15015494
[13] Fang Qi, Michele Carbone, Haining Yang, Giovanni Gaudino. Simian virus 40 transformation, malignant mesothelioma and brain tumors. Expert Rev Respir Med. 2011 Oct ;5(5):683-97. PMID: 21955238
[14] Lynn M Crosby, Tanya M Moore, Michael George, Lawrence W Yoon, Marilyn J Easton, Hong Ni, Kevin T Morgan, Anthony B DeAngelo. Transformation of SV40-immortalized human uroepithelial cells by 3-methylcholanthrene increases IFN- and Large T Antigen-induced transcripts. Cancer Cell Int. 2010;10:4. Epub 2010 Feb 23. PMID: 20178601
[15] Rochelle Cutrone, John Lednicky, Glynis Dunn, Paola Rizzo, Maurizio Bocchetta, Konstantin Chumakov, Philip Minor, Michele Carbone. Some oral poliovirus vaccines were contaminated with infectious SV40 after 1961. Cancer Res. 2005 Nov 15 ;65(22):10273-9. PMID:16288015#
[16] Strebel PM, Sutter RW, Cochi SL, et al. Epidemiology of poliomyelitis in the United States one decade after the last reported case of indigenous wild virus-associated disease. Clin Infect Dis 1992;14:568-79.
[17] Alfredo Corallini, Elisa Mazzoni, Angelo Taronna, Marco Manfrini, Giovanni Carandina, Giovanni Guerra, Roberto Guaschino, Francesca Vaniglia, Corrado Magnani, Ferruccio Casali, Riccardo Dolcetti, Caterina Palmonari, Giovanni Rezza, Fernanda Martini, Giuseppe Barbanti-Brodano, Mauro G Tognon. Specific antibodies reacting with simian virus 40 capsid protein mimotopes in serum samples from healthy blood donors. Hum Immunol. 2012 Feb 21. Epub 2012 Feb 21. PMID: 22387152
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