The Importance of Being "Awe Inspired"

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 The Importance Of Being “Awe Inspired”
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Our emotional state has great influence over the degree of inflammation we may suffer from.  Feeling "awe inspired" has been found to be the most powerful emotion in fighting inflammation


The field of positive psychology is providing valuable insights on exactly how our emotions influence our physiology. One are of body function that is very closely tied to our emotional experiences is the functioning of our immune system. Our emotional state not only influences how well we are protected from infection, but also the degree of inflammation that we may suffer from. Two new studies have found that the most powerful emotion in fighting inflammation is the feeling of awe.

Background Data:

While there have been a lot of studies on the impact of emotions on physical health, in general, these emotions are most often all lumped together. Negative emotions like grief, sadness, shame, fear, and anger are all viewed as having pretty much the same effects. The same is true for all positive emotions grouped into the general category of optimism or positive mood. What needs to be answered is if all positive emotions are created equal, or is there a way to boost certain body functions by focusing on experiencing more of a particular positive emotion.

New Data:

In an effort to better understand the different effects of various positive emotions, researchers conducted two studies at the University of California-Berkeley. The first study featured 94 freshman undergraduates who completed a questionnaire and provided a sample of the fluid from their inner cheek (oral mucosal transudate [OMT]). In the second study, 119 freshmen completed a questionnaire on their home computers using a secure website and then went to the lab for a follow up session where OMT was collected and another questionnaire was given.

In both studies interleukin-6 (IL-6) was measured from OMT samples. IL-6 is an important marker for inflammation that is influenced by the immune system. Higher IL-6 levels are associated with greater inflammation. In the first study, a questionnaire known as the Positive and Negative Affect Schedule (PANAS) was used to determine emotional status. In the second study, two additional questionnaires were used, the Dispositional Positive Emotion Scale (DPES) and The Big Five Personality Inventory were added as outcomes measures in addition to PANAS.

In both studies, positive emotions were associated with lower IL-6. In the second study, researchers were able to dig deeper into the type of positive emotion that had the most significant impact on IL-6 levels by examining the seven subscales of the DPES (awe, amusement, compassion, contentment, joy, love, and pride). Surprisingly, they found that awe had the strongest correlation to lower levels of IL-6 compared to any of the other emotions. In fact, only the degree of awe was able to significantly predict levels of IL-6. On the day the OMT was taken in the second study, the participants who reported feeling the most awe, wonder and amazement, that day had the lowest levels of IL-6. Joy, contentment, pride and awe were all strongly correlated with lower levels of IL-6; however, awe was the strongest predictor of low IL-6 levels.

The takeaway message from these studies is that it stresses the importance of fostering feelings of awe in our lives to positively influence the immune system and reduce inflammation.


O.K., let me answer the question "How do I experience more awe in my life?" Well, first of all, awe is often linked to feelings of social connectedness and social exploration. So from a practical perspective, the first step is to become more socially engaged. This goal is especially important if you are older of dealing with depression, because these situations often lead to social isolation. Here are some recommendations to become more socially engaged:

  • Get connected online. Using email, the Internet, and Web-based social networks such as Facebook or Twitter can make a big difference in helping people feel more connected.
  • Encourage positive relationships. A person is never too old to learn how to be a better friend, parent, mentor, or better listener. Personal development is a never-ending process.
  • Join a club or church. In today's world, there are always opportunities to find places to socialize that are positive and healthful.
  • There is perhaps no greater opportunity to feel connected than by finding a way to volunteer time and energy towards a greater good. It is perhaps the most powerful way of connecting to people outside of our deepest personal relationships.

The health benefits of increased socialization are significant. Many of these benefits may be related to fighting inflammation and studies indicate that people who feel connected and have strong social relationships have lower levels of inflammatory markers in their blood.

Next, I would ask the question "What inspires you and causes you to feel awe?" What research shows is that something as simple as listening to music, walking in nature, or being creative, can have a positive impact on health. These effects may be related to feelings of awe.

For me, the things that really make me say "wow" are research studies like this one above. I am constantly reading studies that create an awe-inspired appreciation of the wonder of nature or the way in which our body and mind function. Of course, just looking around at nature or the stars is pretty awe inspiring to me. My message to you is to find a something that you can enjoy on a daily basis that makes you feel awe. It is important!

Get more information on inflammation on's research dashboard. 


Stellar JE, John-Henderson N, Anderson CL, et al. Positive affect and markers of inflammation: Discrete positive emotions predict lower levels of inflammatory cytokines. Emotion. 2015;15(2):129-133.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of GreenMedInfo or its staff.

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