Results for Acetaminophen (Tylenol) Toxicity

Chrysin possesses restorative effect against paracetamol induced hepatotoxicity.

Article Published Date : Oct 31, 2017
Study Type : Animal Study
Additional Links
Substances : Chrysin : CK(147) : AC(93)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(654) : AC(246), Lipid Peroxidation : CK(1632) : AC(631)
Pharmacological Actions : Anti-Apoptotic : CK(2905) : AC(1672), Antioxidants : CK(21528) : AC(8856), Hepatoprotective : CK(5098) : AC(2264)
Additional Keywords : Acetaminophen (Tylenol) Toxicity, Anti-Apoptotic, Antioxidants : CK(303) : AC(126), Chrysin, Hepatoprotective, Lipid Peroxidation
Problem Substances : Acetaminophen, Paracetamol : CK(762) : AC(241)

Commonly taken analgesics could decrease germ cell number and ovarian size in F1 offspring in rats.

Article Published Date : Jan 26, 2016
Study Type : Animal Study
Additional Links
Diseases : Acetaminophen (Tylenol) Toxicity : CK(654) : AC(246), Infertility: Female : CK(541) : AC(127), Prenatal Chemical Exposures : CK(1774) : AC(396)
Additional Keywords : Acetaminophen (Tylenol) Toxicity, Infertility: Female, Prenatal Chemical Exposures, Transgenerational Epigenetic Modification : CK(229) : AC(89)
Problem Substances : Acetaminophen, Analgesic: Non-opioid : CK(34) : AC(5), Indomethacin : CK(71) : AC(33), Paracetamol : CK(762) : AC(241)

Early paracetamol exposure produces major changes in serotonergic and dopaminergic neurotransmission in the prefrontal cortex and striatum.

Article Published Date : Apr 13, 2017
Study Type : Animal Study
Additional Links
Diseases : Acetaminophen (Tylenol) Toxicity : CK(654) : AC(246), Prenatal Chemical Exposures : CK(1774) : AC(396)
Additional Keywords : Acetaminophen : CK(658) : AC(6), Acetaminophen (Tylenol) Toxicity, paracetamol, Prenatal Chemical Exposures
Problem Substances : Acetaminophen, Paracetamol : CK(762) : AC(241)

Lycopene is a natural compound that was able to inhibit the production of ROS and mitigate the damage caused by acetaminophen.

Article Published Date : Jan 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Carotenoids : CK(3269) : AC(832), Lycopene : CK(886) : AC(249)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(654) : AC(246), Liver Damage: Drug-Induced : CK(316) : AC(124), Oxidative Stress : CK(9437) : AC(3550)
Pharmacological Actions : Antioxidants : CK(21528) : AC(8856), Hepatoprotective : CK(5098) : AC(2264), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(727) : AC(442)
Additional Keywords : Acetaminophen (Tylenol) Toxicity, Antioxidants : CK(303) : AC(126), CAROTENOIDS, Hepatoprotective, Liver Damage: Drug-Induced, lycopene, Matrix metalloproteinase-2 (MMP-2) inhibitor, oxidative stress
Problem Substances : Acetaminophen, Paracetamol : CK(762) : AC(241)

Lycopene pretreatment improves hepatotoxicity induced by acetaminophen in mice.

Article Published Date : Jan 31, 2017
Study Type : Animal Study
Additional Links
Substances : Lycopene : CK(886) : AC(249)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(654) : AC(246), Liver Damage: Drug-Induced : CK(316) : AC(124)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Hepatoprotective : CK(5098) : AC(2264), Interleukin-1 beta downregulation : CK(3041) : AC(1567), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(727) : AC(442)
Additional Keywords : Acetaminophen (Tylenol) Toxicity, Anti-Inflammatory Agents, Hepatoprotective, Liver Damage: Drug-Induced, lycopene
Problem Substances : Acetaminophen, Paracetamol : CK(762) : AC(241)

Maternal acetaminophen use during pregnancy was associated with lower performance IQ in 5-year olds.

Article Published Date : Oct 31, 2016
Study Type : Human Study
Additional Links
Diseases : Acetaminophen (Tylenol) Toxicity : CK(654) : AC(246), Prenatal Chemical Exposures : CK(1774) : AC(396)
Additional Keywords : Acetaminophen : CK(658) : AC(6), Acetaminophen (Tylenol) Toxicity, paracetamol, Prenatal Chemical Exposures
Problem Substances : Acetaminophen, Paracetamol : CK(762) : AC(241)

Maternal paracetamol use during pregnancy could be associated with poorer attention and executive function in 5-year-olds.

Article Published Date : Nov 30, 2016
Study Type : Human Study
Additional Links
Diseases : Acetaminophen (Tylenol) Toxicity : CK(654) : AC(246), Prenatal Chemical Exposures : CK(1774) : AC(396)
Additional Keywords : Acetaminophen : CK(658) : AC(6), Acetaminophen (Tylenol) Toxicity, paracetamol, Prenatal Chemical Exposures
Problem Substances : Acetaminophen, Paracetamol : CK(762) : AC(241)

Maternal use of mild analgesics during pregnancy associated with reduced anogenital distance in sons

Article Published Date : Dec 31, 2016
Study Type : Human Study
Additional Links
Diseases : Acetaminophen (Tylenol) Toxicity : CK(654) : AC(246)
Additional Keywords : Acetaminophen : CK(658) : AC(6), Acetaminophen (Tylenol) Toxicity, Analgesic: Non-opioid, Risk Factors : CK(12084) : AC(1737)
Problem Substances : Acetaminophen, Analgesic: Non-opioid : CK(34) : AC(5)

Prenatal and postnatal paracetamol exposure results in modulation of cerebellar neurotransmission with changes concerning mainly 5-HIAA and MHPG levels.

Article Published Date : Nov 30, 2016
Study Type : Animal Study
Additional Links
Diseases : Acetaminophen (Tylenol) Toxicity : CK(654) : AC(246), Prenatal Chemical Exposures : CK(1774) : AC(396)
Additional Keywords : Acetaminophen : CK(658) : AC(6), Acetaminophen (Tylenol) Toxicity, paracetamol, Prenatal Chemical Exposures
Problem Substances : Acetaminophen, Paracetamol : CK(762) : AC(241)
Adverse Pharmacological Actions : Neurotoxic : CK(2424) : AC(562)

Prenatal exposures and the development of childhood wheezing illnesses.

Article Published Date : Mar 31, 2017
Study Type : Review
Additional Links
Diseases : Acetaminophen (Tylenol) Toxicity : CK(654) : AC(246), Prenatal Chemical Exposures : CK(1774) : AC(396), Wheezing: Infants : CK(51) : AC(5)
Additional Keywords : Acetaminophen (Tylenol) Toxicity, Environmental Factors : CK(48) : AC(9), Prenatal Chemical Exposures, Risk Factors : CK(12084) : AC(1737), Wheezing: Infants

The Powerful Aspirin Alternative Your Doctor Never Told You About

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The Powerful Aspirin Alternative Your Doctor Never Told You About

Given the newly released cardiovascular disease prevention guidelines recommending against daily low-dose aspirin use, natural, safe and effective alternatives are needed now more than ever. Thankfully, one particularly therapeutic alternative has been known about by the biomedical research community for decades...

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This data provide strong evidence that prenatal acetaminophen interferes with maternal immune and endocrine adaptation to pregnancy.

Article Published Date : Sep 30, 2015
Study Type : Animal Study
Additional Links
Diseases : Acetaminophen (Tylenol) Toxicity : CK(654) : AC(246), Asthma : CK(2488) : AC(486), Prenatal Chemical Exposures : CK(1774) : AC(396)
Additional Keywords : Acetaminophen : CK(658) : AC(6), Acetaminophen (Tylenol) Toxicity, Asthma : CK(4) : AC(2), paracetamol, Prenatal Chemical Exposures
Problem Substances : Acetaminophen, Paracetamol : CK(762) : AC(241)
Adverse Pharmacological Actions : Immunotoxic : CK(460) : AC(104)

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