Results for Acetaminophen (Tylenol) Toxicity

Chrysin possesses restorative effect against paracetamol induced hepatotoxicity.

Article Published Date : Oct 31, 2017
Study Type : Animal Study
Additional Links
Substances : Chrysin : CK(445) : AC(274)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(902) : AC(362), Lipid Peroxidation : CK(2057) : AC(806)
Pharmacological Actions : Anti-Apoptotic : CK(5568) : AC(3160), Antioxidants : CK(34551) : AC(14499), Hepatoprotective : CK(8989) : AC(3831)
Additional Keywords : Acetaminophen (Tylenol) Toxicity, Anti-Apoptotic, Antioxidants : CK(303) : AC(126), Chrysin, Hepatoprotective, Lipid Peroxidation
Problem Substances : Acetaminophen, Paracetamol : CK(863) : AC(298)

Commonly taken analgesics could decrease germ cell number and ovarian size in F1 offspring in rats.

Article Published Date : Jan 26, 2016
Study Type : Animal Study
Additional Links
Diseases : Acetaminophen (Tylenol) Toxicity : CK(902) : AC(362), Infertility: Female : CK(822) : AC(197), Prenatal Chemical Exposures : CK(2485) : AC(547)
Additional Keywords : Acetaminophen (Tylenol) Toxicity, Infertility: Female, Prenatal Chemical Exposures, Transgenerational Epigenetic Modification : CK(241) : AC(91)
Problem Substances : Acetaminophen, Analgesic: Non-opioid : CK(34) : AC(5), Indomethacin : CK(112) : AC(54), Paracetamol : CK(863) : AC(298)

Early paracetamol exposure produces major changes in serotonergic and dopaminergic neurotransmission in the prefrontal cortex and striatum.

Article Published Date : Apr 13, 2017
Study Type : Animal Study
Additional Links
Diseases : Acetaminophen (Tylenol) Toxicity : CK(902) : AC(362), Prenatal Chemical Exposures : CK(2485) : AC(547)
Additional Keywords : Acetaminophen : CK(749) : AC(286), Acetaminophen (Tylenol) Toxicity, paracetamol, Prenatal Chemical Exposures
Problem Substances : Acetaminophen, Paracetamol : CK(863) : AC(298)

Lycopene is a natural compound that was able to inhibit the production of ROS and mitigate the damage caused by acetaminophen.

Article Published Date : Jan 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Carotenoids : CK(4462) : AC(1222), Lycopene : CK(1267) : AC(372)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(902) : AC(362), Liver Damage: Drug-Induced : CK(651) : AC(285), Oxidative Stress : CK(14758) : AC(5716)
Pharmacological Actions : Antioxidants : CK(34551) : AC(14499), Hepatoprotective : CK(8989) : AC(3831), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(944) : AC(588)
Additional Keywords : Acetaminophen (Tylenol) Toxicity, Antioxidants : CK(303) : AC(126), CAROTENOIDS, Hepatoprotective, Liver Damage: Drug-Induced, lycopene, Matrix metalloproteinase-2 (MMP-2) inhibitor, oxidative stress
Problem Substances : Acetaminophen, Paracetamol : CK(863) : AC(298)

Lycopene pretreatment improves hepatotoxicity induced by acetaminophen in mice.

Article Published Date : Jan 31, 2017
Study Type : Animal Study
Additional Links
Substances : Lycopene : CK(1267) : AC(372)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(902) : AC(362), Liver Damage: Drug-Induced : CK(651) : AC(285)
Pharmacological Actions : Anti-Inflammatory Agents : CK(39737) : AC(15858), Hepatoprotective : CK(8989) : AC(3831), Interleukin-1 beta downregulation : CK(6063) : AC(2940), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(944) : AC(588)
Additional Keywords : Acetaminophen (Tylenol) Toxicity, Anti-Inflammatory Agents, Hepatoprotective, Liver Damage: Drug-Induced, lycopene
Problem Substances : Acetaminophen, Paracetamol : CK(863) : AC(298)

Maternal acetaminophen use during pregnancy was associated with lower performance IQ in 5-year olds.

Article Published Date : Oct 31, 2016
Study Type : Human Study
Additional Links
Diseases : Acetaminophen (Tylenol) Toxicity : CK(902) : AC(362), Prenatal Chemical Exposures : CK(2485) : AC(547)
Additional Keywords : Acetaminophen : CK(749) : AC(286), Acetaminophen (Tylenol) Toxicity, paracetamol, Prenatal Chemical Exposures
Problem Substances : Acetaminophen, Paracetamol : CK(863) : AC(298)

Maternal paracetamol use during pregnancy could be associated with poorer attention and executive function in 5-year-olds.

Article Published Date : Nov 30, 2016
Study Type : Human Study
Additional Links
Diseases : Acetaminophen (Tylenol) Toxicity : CK(902) : AC(362), Prenatal Chemical Exposures : CK(2485) : AC(547)
Additional Keywords : Acetaminophen : CK(749) : AC(286), Acetaminophen (Tylenol) Toxicity, paracetamol, Prenatal Chemical Exposures
Problem Substances : Acetaminophen, Paracetamol : CK(863) : AC(298)

Maternal use of mild analgesics during pregnancy associated with reduced anogenital distance in sons

Article Published Date : Dec 31, 2016
Study Type : Human Study
Additional Links
Diseases : Acetaminophen (Tylenol) Toxicity : CK(902) : AC(362)
Additional Keywords : Acetaminophen : CK(749) : AC(286), Acetaminophen (Tylenol) Toxicity, Analgesic: Non-opioid, Risk Factors : CK(14901) : AC(2085)
Problem Substances : Acetaminophen, Analgesic: Non-opioid : CK(34) : AC(5)

Prenatal and postnatal paracetamol exposure results in modulation of cerebellar neurotransmission with changes concerning mainly 5-HIAA and MHPG levels.

Article Published Date : Nov 30, 2016
Study Type : Animal Study
Additional Links
Diseases : Acetaminophen (Tylenol) Toxicity : CK(902) : AC(362), Prenatal Chemical Exposures : CK(2485) : AC(547)
Additional Keywords : Acetaminophen : CK(749) : AC(286), Acetaminophen (Tylenol) Toxicity, paracetamol, Prenatal Chemical Exposures
Problem Substances : Acetaminophen, Paracetamol : CK(863) : AC(298)
Adverse Pharmacological Actions : Neurotoxic : CK(2976) : AC(726)

Prenatal exposures and the development of childhood wheezing illnesses.

Article Published Date : Mar 31, 2017
Study Type : Review
Additional Links
Diseases : Acetaminophen (Tylenol) Toxicity : CK(902) : AC(362), Prenatal Chemical Exposures : CK(2485) : AC(547), Wheezing: Infants : CK(61) : AC(6)
Additional Keywords : Acetaminophen (Tylenol) Toxicity, Environmental Factors : CK(48) : AC(9), Prenatal Chemical Exposures, Risk Factors : CK(14901) : AC(2085), Wheezing: Infants

The Powerful Aspirin Alternative Your Doctor Never Told You About

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Given that cardiovascular disease prevention guidelines now recommend against daily low-dose aspirin use, natural, safe and effective alternatives are needed now more than ever. Thankfully, one particularly therapeutic alternative has been known about by the biomedical research community for decades...

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This data provide strong evidence that prenatal acetaminophen interferes with maternal immune and endocrine adaptation to pregnancy.

Article Published Date : Sep 30, 2015
Study Type : Animal Study
Additional Links
Diseases : Acetaminophen (Tylenol) Toxicity : CK(902) : AC(362), Asthma : CK(3242) : AC(707), Prenatal Chemical Exposures : CK(2485) : AC(547)
Additional Keywords : Acetaminophen : CK(749) : AC(286), Acetaminophen (Tylenol) Toxicity, Asthma : CK(39) : AC(8), paracetamol, Prenatal Chemical Exposures
Problem Substances : Acetaminophen, Paracetamol : CK(863) : AC(298)
Adverse Pharmacological Actions : Immunotoxic : CK(512) : AC(131)

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