Results for Anti-Apoptotic

Administration of deep sea minerals can be an effective strategy to improve the life expectancy of diabetic subjects.

Article Published Date : Jun 30, 2016
Study Type : Animal Study
Additional Links
Substances : Water: Deep Sea : CK(54) : AC(23)
Diseases : Diabetic Complications : CK(4678) : AC(1606), Heart Failure : CK(1929) : AC(337)
Pharmacological Actions : Anti-Apoptotic : CK(5568) : AC(3160), Cardioprotective : CK(9504) : AC(2963)
Additional Keywords : Anti-Apoptotic, Cardioprotective, Diabetic Complications, Heart Failure, Water: Deep Sea

Allicin improves cardiac function by protecting against apoptosis in rat model of myocardial infarction.

Article Published Date : Jul 31, 2017
Study Type : Animal Study
Additional Links
Substances : Allicin : CK(360) : AC(196)
Diseases : Myocardial Infarction : CK(2132) : AC(509)
Pharmacological Actions : Anti-Apoptotic : CK(5568) : AC(3160), Cardioprotective : CK(9504) : AC(2963)
Additional Keywords : Allicin, Anti-Apoptotic, Cardioprotective, Myocardial Infarction

Chrysin possesses restorative effect against paracetamol induced hepatotoxicity.

Article Published Date : Oct 31, 2017
Study Type : Animal Study
Additional Links
Substances : Chrysin : CK(445) : AC(274)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(902) : AC(362), Lipid Peroxidation : CK(2057) : AC(806)
Pharmacological Actions : Anti-Apoptotic : CK(5568) : AC(3160), Antioxidants : CK(34551) : AC(14499), Hepatoprotective : CK(8989) : AC(3831)
Additional Keywords : Acetaminophen (Tylenol) Toxicity, Anti-Apoptotic, Antioxidants : CK(303) : AC(126), Chrysin, Hepatoprotective, Lipid Peroxidation
Problem Substances : Acetaminophen, Paracetamol : CK(863) : AC(298)

Diallyl trisulfide suppresses oxidative stress-induced activation of hepatic stellate cells.

Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Garlic : CK(2194) : AC(727)
Diseases : Liver Cirrhosis : CK(919) : AC(230), Oxidative Stress : CK(14758) : AC(5716)
Pharmacological Actions : Anti-Apoptotic : CK(5568) : AC(3160), Antioxidants : CK(34551) : AC(14499)
Additional Keywords : Anti-Apoptotic, Antioxidants : CK(303) : AC(126), Garlic, Liver Cirrhosis, oxidative stress

Eugenol holds potential as a neuroprotective agent against aluminium induced brain toxicity.

Article Published Date : Feb 28, 2017
Study Type : Animal Study
Additional Links
Substances : Eugenol : CK(219) : AC(133)
Diseases : Aluminum Toxicity : CK(735) : AC(318)
Pharmacological Actions : Anti-Apoptotic : CK(5568) : AC(3160), Antioxidants : CK(34551) : AC(14499), Neuroprotective Agents : CK(20061) : AC(7949)
Additional Keywords : aluminum toxicity, Anti-Apoptotic, Antioxidants : CK(303) : AC(126), eugenol, Neuroprotective Agents
Problem Substances : Aluminum Chloride : CK(192) : AC(95)

M. alba has protective effect on diabetic retinopathy.

Article Published Date : Apr 07, 2016
Study Type : Animal Study
Additional Links
Substances : White Mulberry : CK(156) : AC(66)
Diseases : Diabetic Retinopathy : CK(483) : AC(211)
Pharmacological Actions : Anti-Apoptotic : CK(5568) : AC(3160), Anti-Inflammatory Agents : CK(39737) : AC(15858), Hypoglycemic Agents : CK(9221) : AC(2076), Vascular Endothelial Growth Factor Inhibitors : CK(611) : AC(335)
Additional Keywords : Anti-Apoptotic, Anti-Inflammatory Agents, Diabetic Retinopathy, Hypoglycemic Agents, Vascular Endothelial Growth Factor Inhibitors, White Mulberry

Mangiferin induces islet regeneration in aged mice.

Article Published Date : Feb 28, 2018
Study Type : Animal Study
Additional Links
Substances : Mangiferin : CK(376) : AC(223)
Pharmacological Actions : Anti-Apoptotic : CK(5568) : AC(3160), Pancreato Protective Agents : CK(554) : AC(299)
Additional Keywords : Anti-Apoptotic, Mangiferin, Pancreato Protective Agents

Melatonin promotes brain-derived neurotrophic factor expression and anti-apoptotic effects in neonatal hemolytic hyperbilirubinemia.

Article Published Date : Dec 15, 2017
Study Type : Animal Study
Additional Links
Substances : Melatonin : CK(2891) : AC(911)
Diseases : Hyperbilirubinemia: Hereditary : CK(39) : AC(7)
Pharmacological Actions : Anti-Apoptotic : CK(5568) : AC(3160), Brain-derived neurotrophic factor modulator : CK(745) : AC(280)
Additional Keywords : Anti-Apoptotic, Brain-derived neurotrophic factor modulator, Hyperbilirubinemia: Hereditary, melatonin

Panax notoginseng saponins attenuate cardiomyocyte apoptosis through mitochondrial pathway in natural aging rats.

Article Published Date : Jan 31, 2018
Study Type : Animal Study
Additional Links
Substances : Panax Notoginseng : CK(392) : AC(185)
Diseases : Aging: Heart : CK(38) : AC(17)
Pharmacological Actions : Anti-Apoptotic : CK(5568) : AC(3160), Antioxidants : CK(34551) : AC(14499), Cardioprotective : CK(9504) : AC(2963)
Additional Keywords : Aging: Heart, Anti-Apoptotic, Antioxidants : CK(303) : AC(126), Cardioprotective, Panax Notoginseng

Phloretin has an anti-apoptotic effect on cisplatin-induced apoptosis in HEI-OC1 auditory cells.

Article Published Date : Dec 31, 2010
Study Type : In Vitro Study
Additional Links
Substances : Phloretin : CK(232) : AC(137)
Diseases : Chemotherapy-Induced Toxicity: Cisplatin : CK(1246) : AC(601)
Pharmacological Actions : Anti-Apoptotic : CK(5568) : AC(3160), Chemoprotective Agents : CK(4278) : AC(1621), Heme oxygenase-1 inducer : CK(63) : AC(43)
Additional Keywords : Anti-Apoptotic, Chemoprotective Agents, Chemotherapy-Induced Toxicity: Cisplatin, Heme oxygenase-1 inducer, Phloretin

Puerarin inhibited cadmium induced apoptosis in rPT cells by ameliorating the mitochondrial dysfunction.

Article Published Date : Dec 24, 2016
Study Type : In Vitro Study
Additional Links
Substances : Puerarin : CK(777) : AC(388)
Diseases : Cadmium Poisoning : CK(439) : AC(225)
Pharmacological Actions : Anti-Apoptotic : CK(5568) : AC(3160), Bax/Bcl2 ratio: Increase : CK(58) : AC(44)
Additional Keywords : Anti-Apoptotic, Bax/Bcl2, Cadmium, Cadmium Poisoning, Puerarin
Problem Substances : Cadmium : CK(600) : AC(268)

Shikonin attenuated hepatic ischemia/reperfusion injury by inhibiting apoptosis and autophagy.

Article Published Date : Mar 20, 2017
Study Type : Animal Study
Additional Links
Substances : Shikonin : CK(369) : AC(261)
Diseases : Liver Injury: Ischemia/reperfusion : CK(175) : AC(95)
Pharmacological Actions : Anti-Apoptotic : CK(5568) : AC(3160), Autophagy Inhibitors : CK(302) : AC(188), Hepatoprotective : CK(8989) : AC(3831)
Additional Keywords : Anti-Apoptotic, Autophagy Inhibitors : CK(8) : AC(6), Hepatoprotective, Liver Injury: Ischemia/reperfusion, Shikonin

The flavonoid glycoside astragalin may be a new therapeutic agent for the management of menopausal symptoms.

Article Published Date : May 20, 2016
Study Type : Animal Study
Additional Links
Substances : Flavonoids : CK(4698) : AC(2176), White Mulberry : CK(156) : AC(66)
Diseases : Menopausal Syndrome : CK(768) : AC(114)
Pharmacological Actions : Anti-Apoptotic : CK(5568) : AC(3160)
Additional Keywords : Anti-Apoptotic, Flavonoids, Menopausal Syndrome, White Mulberry

These findings indicate hepatic protective effects of deep sea water on diabetes mellitus.

Article Published Date : Jun 29, 2015
Study Type : Animal Study
Additional Links
Substances : Water: Deep Sea : CK(54) : AC(23)
Diseases : Diabetic Complications : CK(4678) : AC(1606)
Pharmacological Actions : Anti-Apoptotic : CK(5568) : AC(3160), Hepatoprotective : CK(8989) : AC(3831)
Additional Keywords : Anti-Apoptotic, Diabetic Complications, Hepatoprotective, Water: Deep Sea

These results demonstrat the radioprotective effect of folic acid supplementation on low dose ionizing radiation-induced genomic instability in vitro.

Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Folic Acid : CK(1317) : AC(206)
Diseases : DNA damage : CK(2301) : AC(842)
Pharmacological Actions : Anti-Apoptotic : CK(5568) : AC(3160), Radioprotective : CK(2398) : AC(713)
Additional Keywords : Anti-Apoptotic, DNA damage, folic acid, Radioprotective
Anti Therapeutic Actions : Low Dose Ionizing Radiation : CK(61) : AC(30)

These results highlight the protective effects of tangeretin against cisplatin-induced acute hepatic injury.

Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Tangeretin : CK(163) : AC(93)
Diseases : Chemotherapy-Induced Toxicity: Cisplatin : CK(1246) : AC(601)
Pharmacological Actions : Anti-Apoptotic : CK(5568) : AC(3160), Anti-Inflammatory Agents : CK(39737) : AC(15858), Antioxidants : CK(34551) : AC(14499), Chemoprotective Agents : CK(4278) : AC(1621)
Additional Keywords : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants : CK(303) : AC(126), Chemoprotective Agents, Chemotherapy-Induced Toxicity: Cisplatin

These results indicate that shikonin treatment may prevent the loss of vision associated with diabetic retinopathy.

Article Published Date : Mar 20, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Shikonin : CK(369) : AC(261)
Diseases : Diabetic Retinopathy : CK(483) : AC(211)
Pharmacological Actions : Anti-Apoptotic : CK(5568) : AC(3160), Anti-Inflammatory Agents : CK(39737) : AC(15858), Cyclooxygenase 2 Inhibitors : CK(2264) : AC(1327)
Additional Keywords : Anti-Apoptotic, Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Diabetic Retinopathy, Shikonin

Vitamin C could remit isoflurane-induced apoptosis and relieve the decline in learning and memory ability of rats.

Article Published Date : Sep 30, 2016
Study Type : Animal Study
Additional Links
Substances : Vitamin C : CK(6066) : AC(1408)
Diseases : Cognitive Decline/Dysfunction : CK(5443) : AC(1065), Surgery: Anesthesiology : CK(141) : AC(28)
Pharmacological Actions : Anti-Apoptotic : CK(5568) : AC(3160)
Additional Keywords : Anti-Apoptotic, Cognitive Decline/Dysfunction, Risk Reduction : CK(17935) : AC(2006), Surgery: Anesthesiology, Vitamin C : CK(48) : AC(13)

Walnut leaf extract exert protective effects against diabetic retinopathy.

Article Published Date : Oct 31, 2017
Study Type : Animal Study
Additional Links
Substances : Walnut : CK(803) : AC(198)
Diseases : Diabetic Retinopathy : CK(483) : AC(211)
Pharmacological Actions : Anti-Apoptotic : CK(5568) : AC(3160), Anti-Inflammatory Agents : CK(39737) : AC(15858), Cyclooxygenase 2 Inhibitors : CK(2264) : AC(1327)
Additional Keywords : Anti-Apoptotic, Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Diabetic Retinopathy, Walnut

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