Results for Anti-Inflammatory Agents

The dietary ingestion of Aloe sterols protected against chronic UVB damage in mouse skin.

Article Published Date : Dec 19, 2016
Study Type : Animal Study
Additional Links
Substances : Aloe Vera : CK(725) : AC(189)
Diseases : Ultraviolet Radiation Induced Damage : CK(461) : AC(215)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Interleukin-1 beta downregulation : CK(3041) : AC(1567), Matrix Metalloproteinase-12 (MMP-12) Inhibitor : CK(13) : AC(7), Matrix Metalloproteinase-13 (MMP-13) Inhibitor : CK(145) : AC(66), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(727) : AC(442), Matrix metalloproteinase-9 (MMP-9) inhibitor : CK(786) : AC(505), Photoprotective : CK(446) : AC(198), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(6736) : AC(2815)
Additional Keywords : Aloe vera, Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Ultraviolet Radiation Induced Damage

The present review supports that targeting chronic inflammation may have a broad application prospect for the prevention and treatment of cancer.

Article Published Date : May 31, 2017
Study Type : Review
Additional Links
Substances : Andrographolide : CK(10) : AC(9), Curcumin : CK(5598) : AC(2788), Green Tea : CK(3450) : AC(1057)
Diseases : Cancers: All : CK(28241) : AC(10590), Inflammation : CK(9572) : AC(3089)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334)
Additional Keywords : Andrographolide, Anti-Inflammatory Agents, Cancers: All, CURCUMIN : CK(2) : AC(1), GREEN TEA, Inflammation : CK(128) : AC(57)

The results show that oleuropein attenuates the progression of heart failure.

Article Published Date : Feb 28, 2017
Study Type : Animal Study
Additional Links
Substances : Oleuropein : CK(226) : AC(136)
Diseases : Heart Failure : CK(1240) : AC(183), Myocardial Infarction : CK(1563) : AC(315), Oxidative Stress : CK(9437) : AC(3550)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856), Interleukin-1 beta downregulation : CK(3041) : AC(1567), Malondialdehyde Down-regulation : CK(2065) : AC(678), Superoxide Dismutase Up-regulation : CK(1403) : AC(551), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(6736) : AC(2815)
Additional Keywords : Anti-Inflammatory Agents, Antioxidants : CK(303) : AC(126), Heart Failure, Myocardial Infarction, Oleuropein, oxidative stress

The results suggest that horseradish root exerts an antiphlogistic activity in human immune cells.

Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Horseradish : CK(34) : AC(10)
Diseases : Inflammation : CK(9572) : AC(3089), Lipopolysaccharide-Induced Toxicity : CK(1764) : AC(1073)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Cyclooxygenase 2 Inhibitors : CK(1589) : AC(926), Prostaglandin PGE2 downregulation : CK(193) : AC(88)
Additional Keywords : Anti-Inflammatory Agents, Horseradish, Inflammation : CK(128) : AC(57), Lipopolysaccharide-Induced Toxicity

There is a growing body of evidence that the consumption of pistachios improves health.

Article Published Date : Dec 14, 2017
Study Type : Review
Additional Links
Substances : Pistachio nut : CK(182) : AC(35)
Diseases : Inflammation : CK(9572) : AC(3089)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856)
Additional Keywords : Anti-Inflammatory Agents, Antioxidants : CK(303) : AC(126), Inflammation : CK(128) : AC(57), Pistachio nut

These findings add new experimental data for potential therapeutic effects of resveratrol in the brain in a model of subacute systemic inflammation.

Article Published Date : Dec 31, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Resveratrol : CK(2037) : AC(1112)
Diseases : Brain Inflammation : CK(1101) : AC(567), Cognitive Decline/Dysfunction : CK(3236) : AC(654)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Neuroprotective Agents : CK(10404) : AC(4396)
Additional Keywords : Anti-Inflammatory Agents, Brain Inflammation, Cognitive Decline/Dysfunction, Dose Response : CK(1712) : AC(683), Neuroprotective Agents, RESVERATROL

These findings demonstrated that MedDiet intervention significantly reduced dietary inflammation scores compared to a low-fat diet.

Article Published Date : Apr 13, 2018
Study Type : Human Study
Additional Links
Diseases : Coronary Artery Disease : CK(2089) : AC(226)
Therapeutic Actions : Dietary Modification: Mediterranean Diet : CK(1494) : AC(173)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334)
Additional Keywords : Anti-Inflammatory Agents, Coronary Artery Disease, Dietary Modification: Mediterranean Diet

These findings strongly suggest that the anti-inflammatory actions of Thymoquinone are caused by suppression of IRAK-linked AP-1/NF-κB pathways.

Article Published Date : Feb 19, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Thymoquinone : CK(774) : AC(451)
Diseases : Inflammation : CK(9572) : AC(3089)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Cyclooxygenase 2 Inhibitors : CK(1589) : AC(926), Interleukin-1 beta downregulation : CK(3041) : AC(1567), Interleukin-6 Downregulation : CK(5029) : AC(1994), NF-kappaB Inhibitor : CK(3536) : AC(2098), Nitric Oxide Inhibitor : CK(498) : AC(258), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(6736) : AC(2815)
Additional Keywords : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Inflammation : CK(128) : AC(57), Interleukin-1 beta downregulation, thymoquinone

These findings suggested that berberine may reduce insulin resistance.

Article Published Date : Jan 23, 2018
Study Type : Animal Study
Additional Links
Substances : Berberine : CK(1280) : AC(627)
Diseases : Insulin Resistance : CK(3522) : AC(792)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Gastrointestinal Agents : CK(3145) : AC(843), Hypoglycemic Agents : CK(5366) : AC(1338), Hypolipidemic : CK(5358) : AC(1221)
Additional Keywords : Anti-Inflammatory Agents, Berberine, Gastrointestinal Agents, Hypoglycemic Agents, Hypolipidemic, Insulin Resistance

These results highlight the protective effects of tangeretin against cisplatin-induced acute hepatic injury.

Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Tangeretin : CK(38) : AC(24)
Diseases : Chemotherapy-Induced Toxicity: Cisplatin : CK(881) : AC(388)
Pharmacological Actions : Anti-Apoptotic : CK(2905) : AC(1672), Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856), Chemoprotective Agents : CK(2322) : AC(906)
Additional Keywords : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants : CK(303) : AC(126), Chemoprotective Agents, Chemotherapy-Induced Toxicity: Cisplatin

These results indicate that shikonin treatment may prevent the loss of vision associated with diabetic retinopathy.

Article Published Date : Mar 20, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Shikonin : CK(108) : AC(63)
Diseases : Diabetic Retinopathy : CK(290) : AC(121)
Pharmacological Actions : Anti-Apoptotic : CK(2905) : AC(1672), Anti-Inflammatory Agents : CK(20859) : AC(8334), Cyclooxygenase 2 Inhibitors : CK(1589) : AC(926)
Additional Keywords : Anti-Apoptotic, Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Diabetic Retinopathy, Shikonin

These results reveal an immunosuppressive effect of cannabinoid preparations.

Article Published Date : Dec 31, 2016
Study Type : Human Study
Additional Links
Substances : Cannabinoids : CK(2052) : AC(692)
Diseases : Inflammation : CK(9572) : AC(3089), Pancreatitis: Chronic : CK(4) : AC(4)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Immunosuppressive Agents : CK(80) : AC(43)
Additional Keywords : Anti-Inflammatory Agents, Cannabinoids, Immunosuppressive Agents, Inflammation : CK(128) : AC(57), Pancreatitis: Chronic

These results suggest that ethanolic extracts of adlay had an inhibitory effect on allergic response.

Article Published Date : Feb 23, 2010
Study Type : In Vitro Study
Additional Links
Substances : Adlay : CK(1) : AC(1)
Diseases : Allergies : CK(1381) : AC(280)
Pharmacological Actions : Anti-Allergic Agents : CK(442) : AC(150), Anti-Inflammatory Agents : CK(20859) : AC(8334), Interleukin-4 downregulation : CK(355) : AC(128), Interleukin-6 Downregulation : CK(5029) : AC(1994), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(6736) : AC(2815)
Additional Keywords : Adlay, allergies, Anti-Allergic Agents, Anti-Inflammatory Agents, Plant Extracts : CK(14140) : AC(5210)

These results suggest that tangeretin improves insulin resistance by attenuating obesity-induced inflammation in adipose tissue.

Article Published Date : Feb 28, 2017
Study Type : In Vitro Study
Additional Links
Substances : Tangeretin : CK(38) : AC(24)
Diseases : Inflammation : CK(9572) : AC(3089), Insulin Resistance : CK(3522) : AC(792), Obesity : CK(6879) : AC(1686)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Cyclooxygenase 2 Inhibitors : CK(1589) : AC(926), Insulin Sensitizers : CK(1185) : AC(244), Interleukin-1 beta downregulation : CK(3041) : AC(1567), Interleukin-6 Downregulation : CK(5029) : AC(1994), Nitric Oxide Inhibitor : CK(498) : AC(258)
Additional Keywords : Anti-Inflammatory Agents, Inflammation : CK(128) : AC(57), Insulin Resistance, obesity, Tangeretin

This report confirms the anti-inflammatory potential of this traditionally employed herbal medicine in vitro.

Article Published Date : Dec 31, 2011
Study Type : In Vitro Study
Additional Links
Substances : Justicia gendarussa : CK(1) : AC(1)
Diseases : Inflammation : CK(9572) : AC(3089), Lipopolysaccharide-Induced Toxicity : CK(1764) : AC(1073)
Pharmacological Actions : 5-Lipoxygenase Inhibitor : CK(35) : AC(21), Anti-Inflammatory Agents : CK(20859) : AC(8334), Cyclooxygenase 2 Inhibitors : CK(1589) : AC(926), Interleukin-6 Downregulation : CK(5029) : AC(1994), NF-kappaB Inhibitor : CK(3536) : AC(2098)
Additional Keywords : 5-Lipoxygenase Inhibitor, Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Inflammation : CK(128) : AC(57), Interleukin-6 Downregulation, Justicia gendarussa, Lipopolysaccharide-Induced Toxicity, NF-kappaB Inhibitor, Plant Extracts : CK(14140) : AC(5210)

This review aims to summarize an overview on the neuroprotective effects of andrographolide and exemplifies the essential mechanisms involved.

Article Published Date : Jul 26, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Andrographolide : CK(10) : AC(9)
Diseases : Stroke : CK(2862) : AC(421)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856), Heme oxygenase-1 up-regulation : CK(624) : AC(373), Neuroprotective Agents : CK(10404) : AC(4396), NF-kappaB Inhibitor : CK(3536) : AC(2098), Nrf2 activation : CK(1584) : AC(916)
Additional Keywords : Andrographolide, Anti-Inflammatory Agents, Antioxidants : CK(303) : AC(126), stroke

This review discusses both the current knowledge of and new perspectives for honey therapy in ophthalmology.

Article Published Date : Dec 31, 2015
Study Type : Review
Additional Links
Substances : Honey : CK(920) : AC(247)
Diseases : Eye Diseases : CK(1863) : AC(464), Wound Healing : CK(1362) : AC(477)
Pharmacological Actions : Anti-Bacterial Agents : CK(2894) : AC(1251), Anti-Inflammatory Agents : CK(20859) : AC(8334)
Additional Keywords : Anti-Bacterial Agents, Anti-Inflammatory Agents, Eye Diseases, Honey : CK(1) : AC(1), wound healing

This study demonstrated that melatonin pretreatment attenuated lung ischaemia-reperfusion injury.

Article Published Date : Jan 14, 2018
Study Type : Animal Study
Additional Links
Substances : Melatonin : CK(1911) : AC(647)
Diseases : Ischemia : CK(392) : AC(198)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Interleukin-1 beta downregulation : CK(3041) : AC(1567), NF-kappaB Inhibitor : CK(3536) : AC(2098), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(6736) : AC(2815)
Additional Keywords : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Ischemia, melatonin

Thymoquinone abolishes a number of factors known to be involved in rheumatoid arthritis pathogenesis.

Article Published Date : Dec 31, 2010
Study Type : Animal Study
Additional Links
Substances : Thymoquinone : CK(774) : AC(451)
Diseases : Inflammation : CK(9572) : AC(3089), Rheumatoid Arthritis : CK(1546) : AC(328)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Antiproliferative : CK(6801) : AC(5032), Cyclooxygenase 2 Inhibitors : CK(1589) : AC(926), Interleukin-1 beta downregulation : CK(3041) : AC(1567), NF-kappaB Inhibitor : CK(3536) : AC(2098), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(6736) : AC(2815)
Additional Keywords : Anti-Inflammatory Agents, Antiproliferative : CK(65) : AC(52), Inflammation : CK(128) : AC(57), rheumatoid arthritis, thymoquinone

Thymoquinone may be considered for topical application alone in the treatment of acute otitis externa.

Article Published Date : Dec 13, 2017
Study Type : Animal Study
Additional Links
Substances : Thymoquinone : CK(774) : AC(451)
Diseases : Otitis : CK(10) : AC(1)
Pharmacological Actions : Anti-Bacterial Agents : CK(2894) : AC(1251), Anti-Inflammatory Agents : CK(20859) : AC(8334)
Additional Keywords : Anti-Bacterial Agents, Anti-Inflammatory Agents, Otitis, Superiority of Natural Substances versus Drugs : CK(1644) : AC(347), thymoquinone

Treatment by Thymoquinone restores inflammation-induced liver fibrosis.

Article Published Date : Oct 31, 2017
Study Type : Animal Study
Additional Links
Substances : Thymoquinone : CK(774) : AC(451)
Diseases : Fibrosis: Liver : CK(32) : AC(13), Inflammation : CK(9572) : AC(3089), Lipopolysaccharide-Induced Toxicity : CK(1764) : AC(1073)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334)
Additional Keywords : Anti-Inflammatory Agents, Fibrosis: Liver, Inflammation : CK(128) : AC(57), Lipopolysaccharide-Induced Toxicity, thymoquinone

Vitamin C is essential for preventing and improving insulin resistance.

Article Published Date : Apr 02, 2018
Study Type : Animal Study
Additional Links
Diseases : Insulin Disorders : CK(15) : AC(4), Vitamin C Deficiency : CK(427) : AC(82)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334)
Additional Keywords : Anti-Inflammatory Agents, Insulin Disorders, Vitamin C Deficiency

Vitamin D supplementation may have a beneficial role in ulcerative colitis patients.

Article Published Date : Jun 30, 2016
Study Type : Human Study
Additional Links
Substances : Vitamin D : CK(8897) : AC(1260)
Diseases : C-Reactive Protein : CK(3134) : AC(310), Ulcerative Colitis : CK(666) : AC(196)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334)
Additional Keywords : Anti-Inflammatory Agents, C-Reactive Protein, Gene Expression Regulation : CK(1141) : AC(501), Ulcerative Colitis, VITAMIN D

Vitamin K2 may be a potential therapeutic agent in the treatment of prostate cancer.

Article Published Date : Dec 31, 2012
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Vitamin K2 : CK(462) : AC(74)
Diseases : Prostate Cancer : CK(2407) : AC(834)
Pharmacological Actions : Angiogenesis Inhibitors : CK(488) : AC(296), Anti-Inflammatory Agents : CK(20859) : AC(8334), Anti-metastatic : CK(1972) : AC(1481), Apoptotic : CK(6986) : AC(5304), NF-kappaB Inhibitor : CK(3536) : AC(2098)
Additional Keywords : Angiogenesis Inhibitors, Anti-Inflammatory Agents, Anti-metastatic, Apoptotic, NF-kappaB Inhibitor, prostate cancer, Vitamin K2 : CK(1) : AC(1)

Walnut leaf extract exert protective effects against diabetic retinopathy.

Article Published Date : Oct 31, 2017
Study Type : Animal Study
Additional Links
Substances : Walnut : CK(589) : AC(137)
Diseases : Diabetic Retinopathy : CK(290) : AC(121)
Pharmacological Actions : Anti-Apoptotic : CK(2905) : AC(1672), Anti-Inflammatory Agents : CK(20859) : AC(8334), Cyclooxygenase 2 Inhibitors : CK(1589) : AC(926)
Additional Keywords : Anti-Apoptotic, Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Diabetic Retinopathy, Walnut

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