Results for Anti-metastatic

A comprehensive review on anticancer mechanisms of crocin.

Article Published Date : Jul 02, 2017
Study Type : Review
Additional Links
Substances : Crocin : CK(732) : AC(311)
Diseases : Cancers: All : CK(36238) : AC(14313)
Pharmacological Actions : Anti-metastatic : CK(2863) : AC(2176), Antiproliferative : CK(9968) : AC(7464), Apoptotic : CK(9566) : AC(7365), Chemotherapeutic : CK(4337) : AC(1618), Telomerase Inhibitor : CK(98) : AC(65)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(75) : AC(61), Apoptotic, Cancers: All, Chemotherapeutic, Crocin, Telomerase Inhibitor

A polysaccharide from Punica granatum has an inhibitory effect on metastasis.

Article Published Date : May 24, 2017
Study Type : Animal Study
Additional Links
Substances : Pomegranate : CK(1799) : AC(572)
Diseases : Cancer Metastasis : CK(958) : AC(540), Lung Cancer: Metastatic : CK(52) : AC(21)
Pharmacological Actions : Anti-metastatic : CK(2863) : AC(2176)
Additional Keywords : Anti-metastatic, Cancer Metastasis, Lung Cancer: Metastatic, pomegranate

A review of the multiple targets and signalling pathways of ginsenosides in cancers.

Article Published Date : Dec 31, 2015
Study Type : Review
Additional Links
Substances : Ginsenosides : CK(2640) : AC(1452)
Diseases : Cancers: All : CK(36238) : AC(14313)
Pharmacological Actions : Anti-Inflammatory Agents : CK(39433) : AC(15735), Anti-metastatic : CK(2863) : AC(2176), Antiproliferative : CK(9968) : AC(7464), Cell cycle arrest : CK(2120) : AC(1715)
Additional Keywords : Anti-Inflammatory Agents, Anti-metastatic, Antiproliferative : CK(75) : AC(61), Cancers: All, Cell cycle arrest, Ginsenosides

An extract of Litchi seed has potential for development into a safe and potent alternative therapy for prostate cancer patients.

Article Published Date : Jan 29, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Litchi : CK(35) : AC(23)
Diseases : Prostate Cancer : CK(2793) : AC(1043)
Pharmacological Actions : Anti-metastatic : CK(2863) : AC(2176), Apoptotic : CK(9566) : AC(7365), Cell cycle arrest : CK(2120) : AC(1715), P21 Activation : CK(206) : AC(144)
Additional Keywords : Anti-metastatic, Apoptotic, Cell cycle arrest, Litchi, P21 Activation, Plant Extracts : CK(18694) : AC(6760), prostate cancer

Curcumin exerts its tumor suppressive function via inhibition of NEDD4 oncoprotein in glioma cancer cells.

Article Published Date : Jun 07, 2017
Study Type : In Vitro Study
Additional Links
Substances : Curcumin : CK(7150) : AC(3267)
Diseases : Glioma : CK(672) : AC(307)
Pharmacological Actions : Anti-metastatic : CK(2863) : AC(2176), Antiproliferative : CK(9968) : AC(7464), Apoptotic : CK(9566) : AC(7365)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(75) : AC(61), Apoptotic, CURCUMIN : CK(25) : AC(18), Glioma

Delta-tocotrienol inhibits pancreatic cancer stem-like cells and prevents pancreatic cancer metastasis.

Article Published Date : May 08, 2017
Study Type : In Vitro Study
Additional Links
Substances : Tocotrienol: Delta : CK(74) : AC(33), Vitamin E : CK(3039) : AC(570)
Diseases : Pancreatic Cancer : CK(1546) : AC(563)
Pharmacological Actions : Anti-metastatic : CK(2863) : AC(2176), Antiproliferative : CK(9968) : AC(7464), Chemopreventive : CK(6568) : AC(2159)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(75) : AC(61), Cancer Stem Cells : CK(501) : AC(365), Chemopreventive, Pancreatic Cancer : CK(2) : AC(2), Tocotrienol: Delta, VITAMIN E

Garcinone E exerts anticancer activities by inducing apoptosis and suppressing migration and invasion in ovarian cancer cells.

Article Published Date : Sep 05, 2017
Study Type : In Vitro Study
Additional Links
Substances : Garcinia Mangostana : CK(22) : AC(13)
Diseases : Ovarian Cancer : CK(1027) : AC(507)
Pharmacological Actions : Anti-metastatic : CK(2863) : AC(2176), Apoptotic : CK(9566) : AC(7365), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(944) : AC(588), Matrix metalloproteinase-9 (MMP-9) inhibitor : CK(1139) : AC(718)
Additional Keywords : Anti-metastatic, Apoptotic, Garcinia Mangostana, ovarian cancer

Genistein inhibits the growth and regulates the migration and invasion abilities of melanoma.

Article Published Date : Mar 27, 2017
Study Type : In Vitro Study
Additional Links
Substances : Genistein : CK(945) : AC(434)
Diseases : Melanoma : CK(922) : AC(551)
Pharmacological Actions : Anti-metastatic : CK(2863) : AC(2176)
Additional Keywords : Anti-metastatic, Genistein, melanoma

Ginsenoside Rb1 may be a potential therapeutic candidate for the treatment of ovarian cancer.

Article Published Date : Sep 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Ginsenosides : CK(2640) : AC(1452)
Diseases : Ovarian Cancer : CK(1027) : AC(507)
Pharmacological Actions : Anti-metastatic : CK(2863) : AC(2176)
Additional Keywords : Anti-metastatic, Ginsenosides, ovarian cancer

Hesperidin inhibited the migratory and invasive capabilities of A549 human non-small cell lung cancer cells.

Article Published Date : Mar 27, 2018
Study Type : In Vitro Study
Additional Links
Substances : Hesperidin : CK(951) : AC(359)
Diseases : Non-Small-Cell Lung Carcinoma : CK(85) : AC(61)
Pharmacological Actions : Anti-metastatic : CK(2863) : AC(2176), Matrix metalloproteinase-9 (MMP-9) inhibitor : CK(1139) : AC(718)
Additional Keywords : Anti-metastatic, Hesperidin, Matrix metalloproteinase-9 (MMP-9) inhibitor, Non-Small-Cell Lung Carcinoma

Increase in motility and invasiveness of MCF7 cancer cells induced by nicotine is abolished by melatonin.

Article Published Date : Jan 15, 2018
Study Type : In Vitro Study
Additional Links
Substances : Melatonin : CK(2891) : AC(911)
Diseases : Breast Cancer : CK(8276) : AC(3032), Nicotine/Tobacco Toxicity : CK(273) : AC(108)
Pharmacological Actions : Anti-metastatic : CK(2863) : AC(2176)
Additional Keywords : Anti-metastatic, Breast Cancer : CK(113) : AC(34), melatonin, Nicotine/Tobacco Toxicity

Puerarin can inhibit the adhesion, invasion and migration of oophoroma HO-8910 cells.

Article Published Date : Jun 30, 2009
Study Type : In Vitro Study
Additional Links
Substances : Puerarin : CK(777) : AC(388)
Diseases : Cancer Metastasis : CK(958) : AC(540), Ovarian Cancer : CK(1027) : AC(507)
Pharmacological Actions : Anti-metastatic : CK(2863) : AC(2176)
Additional Keywords : Anti-metastatic, Cancer Metastasis, ovarian cancer, Puerarin

Resveratrol prevents endothelial cells injury in high-dose interleukin-2 therapy against melanoma.

Article Published Date : Dec 31, 2011
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol : CK(3223) : AC(1510)
Diseases : Lung Cancer : CK(3062) : AC(1428), Melanoma : CK(922) : AC(551)
Pharmacological Actions : Anti-metastatic : CK(2863) : AC(2176), Chemoprotective Agents : CK(4246) : AC(1618), Chemosensitizer : CK(1644) : AC(1266)
Additional Keywords : Anti-metastatic, Chemoprotective Agents, Chemosensitizer, lung cancer, melanoma, RESVERATROL

Shikonin and temozolomide may constitute a powerful new tool for Glioblastoma treatment by reducing therapy resistance and tumor recurrence.

Article Published Date : Apr 10, 2017
Study Type : Human In Vitro
Additional Links
Substances : Shikonin : CK(369) : AC(261)
Diseases : Glioblastoma : CK(709) : AC(396)
Pharmacological Actions : Anti-metastatic : CK(2863) : AC(2176), Antiproliferative : CK(9968) : AC(7464), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(944) : AC(588), Matrix metalloproteinase-9 (MMP-9) inhibitor : CK(1139) : AC(718)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(75) : AC(61), Chemotherapeutic Synergy: Temozolomide : CK(65) : AC(49), Glioblastoma, Shikonin

The cytotoxic effects of the Stanley and Fortress onion varieties were strongest among the selected cultivars.

Article Published Date : May 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Onion : CK(511) : AC(151)
Diseases : Colorectal Cancer : CK(4884) : AC(2273)
Pharmacological Actions : Anti-metastatic : CK(2863) : AC(2176), Antiproliferative : CK(9968) : AC(7464)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(75) : AC(61), COLORECTAL CANCER, Cultivars : CK(12) : AC(10), Onion

These findings provide new insights into the antimetastatic mechanism of baicalein.

Article Published Date : Nov 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Baicalein : CK(312) : AC(202)
Diseases : Breast Cancer: Triple Negative : CK(970) : AC(659)
Pharmacological Actions : Anti-metastatic : CK(2863) : AC(2176)
Additional Keywords : Anti-metastatic, Baicalein, Breast Cancer: Triple Negative

These findings suggested that betulinic acid might be a potential agent for inhibiting the growth and metastasis of breast cancer.

Article Published Date : Jan 08, 2018
Study Type : In Vitro Study
Additional Links
Substances : Betulinic acid : CK(254) : AC(178)
Diseases : Breast Cancer : CK(8276) : AC(3032)
Pharmacological Actions : Anti-metastatic : CK(2863) : AC(2176), Matrix metalloproteinase-9 (MMP-9) inhibitor : CK(1139) : AC(718)
Additional Keywords : Anti-metastatic, Betulinic acid, Breast Cancer : CK(113) : AC(34), Matrix metalloproteinase-9 (MMP-9) inhibitor

This is the first report suggesting selective anti-proliferative and anti-metastatic attributes of papaya leaf juice extract against prostatic diseases.

Article Published Date : Feb 25, 2017
Study Type : In Vitro Study
Additional Links
Substances : Papaya : CK(309) : AC(124)
Diseases : Prostate Cancer : CK(2793) : AC(1043), Prostatic Hyperplasia: Benign : CK(591) : AC(146)
Pharmacological Actions : Anti-metastatic : CK(2863) : AC(2176), Antiproliferative : CK(9968) : AC(7464)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(75) : AC(61), Papaya, prostate cancer, Prostatic Hyperplasia: Benign, Selective Antiproliferation : CK(47) : AC(40)

This study demonstrates the anti-metastatic and anti-EMT activities of Antrodia camphorate.

Article Published Date : Aug 16, 2017
Study Type : In Vitro Study
Additional Links
Substances : Antrodia camphorata : CK(52) : AC(33)
Diseases : Colon Cancer : CK(1917) : AC(1201)
Pharmacological Actions : Anti-metastatic : CK(2863) : AC(2176), Antineoplastic Agents : CK(2235) : AC(1468), Antiproliferative : CK(9968) : AC(7464), Chemopreventive : CK(6568) : AC(2159)
Additional Keywords : Anti-metastatic, Antineoplastic Agents : CK(78) : AC(35), Antiproliferative : CK(75) : AC(61), Antrodia camphorata, Chemopreventive, COLON CANCER

Thymoquinone inhibits the migration and invasion of cervical cancer cells.

Article Published Date : Dec 03, 2017
Study Type : In Vitro Study
Additional Links
Substances : Thymoquinone : CK(1178) : AC(692)
Diseases : Cervical Cancer : CK(974) : AC(594)
Pharmacological Actions : Anti-metastatic : CK(2863) : AC(2176)
Additional Keywords : Anti-metastatic, Cervical Cancer, thymoquinone

Vitamin K2 may be a potential therapeutic agent in the treatment of prostate cancer.

Article Published Date : Dec 31, 2012
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Vitamin K2 : CK(560) : AC(91)
Diseases : Prostate Cancer : CK(2793) : AC(1043)
Pharmacological Actions : Angiogenesis Inhibitors : CK(720) : AC(478), Anti-Inflammatory Agents : CK(39433) : AC(15735), Anti-metastatic : CK(2863) : AC(2176), Apoptotic : CK(9566) : AC(7365), NF-kappaB Inhibitor : CK(5918) : AC(3444)
Additional Keywords : Angiogenesis Inhibitors, Anti-Inflammatory Agents, Anti-metastatic, Apoptotic, NF-kappaB Inhibitor, prostate cancer, Vitamin K2 : CK(16) : AC(6)

Withaferin A directly inhibits the proliferation and metastatic activity of gastric cancer cells.

Article Published Date : Jun 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Ashwagandha : CK(748) : AC(301)
Diseases : Gastric Cancer : CK(1618) : AC(724)
Pharmacological Actions : Anti-metastatic : CK(2863) : AC(2176), Antiproliferative : CK(9968) : AC(7464), Apoptotic : CK(9566) : AC(7365), Cell cycle arrest : CK(2120) : AC(1715)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(75) : AC(61), Apoptotic, Ashwagandha, Cell cycle arrest, gastric cancer

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