Results for Anti-metastatic

A comprehensive review on anticancer mechanisms of crocin.

Article Published Date : Jul 02, 2017
Study Type : Review
Additional Links
Substances : Crocin : CK(732) : AC(311)
Diseases : Cancers: All : CK(36404) : AC(14363)
Pharmacological Actions : Anti-metastatic : CK(2870) : AC(2182), Antiproliferative : CK(10001) : AC(7491), Apoptotic : CK(9585) : AC(7379), Chemotherapeutic : CK(4390) : AC(1635), Telomerase Inhibitor : CK(98) : AC(65)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(75) : AC(61), Apoptotic, Cancers: All, Chemotherapeutic, Crocin, Telomerase Inhibitor

A polysaccharide from Punica granatum has an inhibitory effect on metastasis.

Article Published Date : May 24, 2017
Study Type : Animal Study
Additional Links
Substances : Pomegranate : CK(1800) : AC(573)
Diseases : Cancer Metastasis : CK(961) : AC(542), Lung Cancer: Metastatic : CK(52) : AC(21)
Pharmacological Actions : Anti-metastatic : CK(2870) : AC(2182)
Additional Keywords : Anti-metastatic, Cancer Metastasis, Lung Cancer: Metastatic, pomegranate

A review of the multiple targets and signalling pathways of ginsenosides in cancers.

Article Published Date : Dec 31, 2015
Study Type : Review
Additional Links
Substances : Ginsenosides : CK(2640) : AC(1452)
Diseases : Cancers: All : CK(36404) : AC(14363)
Pharmacological Actions : Anti-Inflammatory Agents : CK(39739) : AC(15859), Anti-metastatic : CK(2870) : AC(2182), Antiproliferative : CK(10001) : AC(7491), Cell cycle arrest : CK(2120) : AC(1715)
Additional Keywords : Anti-Inflammatory Agents, Anti-metastatic, Antiproliferative : CK(75) : AC(61), Cancers: All, Cell cycle arrest, Ginsenosides

An extract of Litchi seed has potential for development into a safe and potent alternative therapy for prostate cancer patients.

Article Published Date : Jan 29, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Litchi : CK(35) : AC(23)
Diseases : Prostate Cancer : CK(2805) : AC(1046)
Pharmacological Actions : Anti-metastatic : CK(2870) : AC(2182), Apoptotic : CK(9585) : AC(7379), Cell cycle arrest : CK(2120) : AC(1715), P21 Activation : CK(206) : AC(144)
Additional Keywords : Anti-metastatic, Apoptotic, Cell cycle arrest, Litchi, P21 Activation, Plant Extracts : CK(18762) : AC(6782), prostate cancer

Curcumin exerts its tumor suppressive function via inhibition of NEDD4 oncoprotein in glioma cancer cells.

Article Published Date : Jun 07, 2017
Study Type : In Vitro Study
Additional Links
Substances : Curcumin : CK(7260) : AC(3326)
Diseases : Glioma : CK(681) : AC(312)
Pharmacological Actions : Anti-metastatic : CK(2870) : AC(2182), Antiproliferative : CK(10001) : AC(7491), Apoptotic : CK(9585) : AC(7379)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(75) : AC(61), Apoptotic, CURCUMIN : CK(25) : AC(18), Glioma

Delta-tocotrienol inhibits pancreatic cancer stem-like cells and prevents pancreatic cancer metastasis.

Article Published Date : May 08, 2017
Study Type : In Vitro Study
Additional Links
Substances : Tocotrienol: Delta : CK(74) : AC(33), Vitamin E : CK(3040) : AC(571)
Diseases : Pancreatic Cancer : CK(1547) : AC(564)
Pharmacological Actions : Anti-metastatic : CK(2870) : AC(2182), Antiproliferative : CK(10001) : AC(7491), Chemopreventive : CK(6580) : AC(2166)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(75) : AC(61), Cancer Stem Cells : CK(501) : AC(365), Chemopreventive, Pancreatic Cancer : CK(2) : AC(2), Tocotrienol: Delta, VITAMIN E

Garcinone E exerts anticancer activities by inducing apoptosis and suppressing migration and invasion in ovarian cancer cells.

Article Published Date : Sep 05, 2017
Study Type : In Vitro Study
Additional Links
Substances : Garcinia Mangostana : CK(22) : AC(13)
Diseases : Ovarian Cancer : CK(1029) : AC(509)
Pharmacological Actions : Anti-metastatic : CK(2870) : AC(2182), Apoptotic : CK(9585) : AC(7379), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(944) : AC(588), Matrix metalloproteinase-9 (MMP-9) inhibitor : CK(1141) : AC(720)
Additional Keywords : Anti-metastatic, Apoptotic, Garcinia Mangostana, ovarian cancer

Genistein inhibits the growth and regulates the migration and invasion abilities of melanoma.

Article Published Date : Mar 27, 2017
Study Type : In Vitro Study
Additional Links
Substances : Genistein : CK(945) : AC(434)
Diseases : Melanoma : CK(924) : AC(552)
Pharmacological Actions : Anti-metastatic : CK(2870) : AC(2182)
Additional Keywords : Anti-metastatic, Genistein, melanoma

Ginsenoside Rb1 may be a potential therapeutic candidate for the treatment of ovarian cancer.

Article Published Date : Sep 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Ginsenosides : CK(2640) : AC(1452)
Diseases : Ovarian Cancer : CK(1029) : AC(509)
Pharmacological Actions : Anti-metastatic : CK(2870) : AC(2182)
Additional Keywords : Anti-metastatic, Ginsenosides, ovarian cancer

Hesperidin inhibited the migratory and invasive capabilities of A549 human non-small cell lung cancer cells.

Article Published Date : Mar 27, 2018
Study Type : In Vitro Study
Additional Links
Substances : Hesperidin : CK(953) : AC(360)
Diseases : Non-Small-Cell Lung Carcinoma : CK(85) : AC(61)
Pharmacological Actions : Anti-metastatic : CK(2870) : AC(2182), Matrix metalloproteinase-9 (MMP-9) inhibitor : CK(1141) : AC(720)
Additional Keywords : Anti-metastatic, Hesperidin, Matrix metalloproteinase-9 (MMP-9) inhibitor, Non-Small-Cell Lung Carcinoma

Increase in motility and invasiveness of MCF7 cancer cells induced by nicotine is abolished by melatonin.

Article Published Date : Jan 15, 2018
Study Type : In Vitro Study
Additional Links
Substances : Melatonin : CK(2891) : AC(911)
Diseases : Breast Cancer : CK(8297) : AC(3043), Nicotine/Tobacco Toxicity : CK(273) : AC(108)
Pharmacological Actions : Anti-metastatic : CK(2870) : AC(2182)
Additional Keywords : Anti-metastatic, Breast Cancer : CK(113) : AC(34), melatonin, Nicotine/Tobacco Toxicity

Puerarin can inhibit the adhesion, invasion and migration of oophoroma HO-8910 cells.

Article Published Date : Jun 30, 2009
Study Type : In Vitro Study
Additional Links
Substances : Puerarin : CK(777) : AC(388)
Diseases : Cancer Metastasis : CK(961) : AC(542), Ovarian Cancer : CK(1029) : AC(509)
Pharmacological Actions : Anti-metastatic : CK(2870) : AC(2182)
Additional Keywords : Anti-metastatic, Cancer Metastasis, ovarian cancer, Puerarin

Resveratrol prevents endothelial cells injury in high-dose interleukin-2 therapy against melanoma.

Article Published Date : Dec 31, 2011
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol : CK(3228) : AC(1513)
Diseases : Lung Cancer : CK(3063) : AC(1429), Melanoma : CK(924) : AC(552)
Pharmacological Actions : Anti-metastatic : CK(2870) : AC(2182), Chemoprotective Agents : CK(4278) : AC(1621), Chemosensitizer : CK(1659) : AC(1271)
Additional Keywords : Anti-metastatic, Chemoprotective Agents, Chemosensitizer, lung cancer, melanoma, RESVERATROL

Shikonin and temozolomide may constitute a powerful new tool for Glioblastoma treatment by reducing therapy resistance and tumor recurrence.

Article Published Date : Apr 10, 2017
Study Type : Human In Vitro
Additional Links
Substances : Shikonin : CK(369) : AC(261)
Diseases : Glioblastoma : CK(729) : AC(403)
Pharmacological Actions : Anti-metastatic : CK(2870) : AC(2182), Antiproliferative : CK(10001) : AC(7491), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(944) : AC(588), Matrix metalloproteinase-9 (MMP-9) inhibitor : CK(1141) : AC(720)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(75) : AC(61), Chemotherapeutic Synergy: Temozolomide : CK(65) : AC(49), Glioblastoma, Shikonin

The cytotoxic effects of the Stanley and Fortress onion varieties were strongest among the selected cultivars.

Article Published Date : May 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Onion : CK(511) : AC(151)
Diseases : Colorectal Cancer : CK(4889) : AC(2276)
Pharmacological Actions : Anti-metastatic : CK(2870) : AC(2182), Antiproliferative : CK(10001) : AC(7491)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(75) : AC(61), COLORECTAL CANCER, Cultivars : CK(12) : AC(10), Onion

These findings provide new insights into the antimetastatic mechanism of baicalein.

Article Published Date : Nov 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Baicalein : CK(312) : AC(202)
Diseases : Breast Cancer: Triple Negative : CK(970) : AC(659)
Pharmacological Actions : Anti-metastatic : CK(2870) : AC(2182)
Additional Keywords : Anti-metastatic, Baicalein, Breast Cancer: Triple Negative

These findings suggested that betulinic acid might be a potential agent for inhibiting the growth and metastasis of breast cancer.

Article Published Date : Jan 08, 2018
Study Type : In Vitro Study
Additional Links
Substances : Betulinic acid : CK(254) : AC(178)
Diseases : Breast Cancer : CK(8297) : AC(3043)
Pharmacological Actions : Anti-metastatic : CK(2870) : AC(2182), Matrix metalloproteinase-9 (MMP-9) inhibitor : CK(1141) : AC(720)
Additional Keywords : Anti-metastatic, Betulinic acid, Breast Cancer : CK(113) : AC(34), Matrix metalloproteinase-9 (MMP-9) inhibitor

This is the first report suggesting selective anti-proliferative and anti-metastatic attributes of papaya leaf juice extract against prostatic diseases.

Article Published Date : Feb 25, 2017
Study Type : In Vitro Study
Additional Links
Substances : Papaya : CK(309) : AC(124)
Diseases : Prostate Cancer : CK(2805) : AC(1046), Prostatic Hyperplasia: Benign : CK(591) : AC(146)
Pharmacological Actions : Anti-metastatic : CK(2870) : AC(2182), Antiproliferative : CK(10001) : AC(7491)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(75) : AC(61), Papaya, prostate cancer, Prostatic Hyperplasia: Benign, Selective Antiproliferation : CK(47) : AC(40)

This study demonstrates the anti-metastatic and anti-EMT activities of Antrodia camphorate.

Article Published Date : Aug 16, 2017
Study Type : In Vitro Study
Additional Links
Substances : Antrodia camphorata : CK(52) : AC(33)
Diseases : Colon Cancer : CK(1920) : AC(1203)
Pharmacological Actions : Anti-metastatic : CK(2870) : AC(2182), Antineoplastic Agents : CK(2235) : AC(1468), Antiproliferative : CK(10001) : AC(7491), Chemopreventive : CK(6580) : AC(2166)
Additional Keywords : Anti-metastatic, Antineoplastic Agents : CK(78) : AC(35), Antiproliferative : CK(75) : AC(61), Antrodia camphorata, Chemopreventive, COLON CANCER

Thymoquinone inhibits the migration and invasion of cervical cancer cells.

Article Published Date : Dec 03, 2017
Study Type : In Vitro Study
Additional Links
Substances : Thymoquinone : CK(1178) : AC(692)
Diseases : Cervical Cancer : CK(975) : AC(595)
Pharmacological Actions : Anti-metastatic : CK(2870) : AC(2182)
Additional Keywords : Anti-metastatic, Cervical Cancer, thymoquinone

Vitamin K2 may be a potential therapeutic agent in the treatment of prostate cancer.

Article Published Date : Dec 31, 2012
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Vitamin K2 : CK(560) : AC(91)
Diseases : Prostate Cancer : CK(2805) : AC(1046)
Pharmacological Actions : Angiogenesis Inhibitors : CK(724) : AC(481), Anti-Inflammatory Agents : CK(39739) : AC(15859), Anti-metastatic : CK(2870) : AC(2182), Apoptotic : CK(9585) : AC(7379), NF-kappaB Inhibitor : CK(5952) : AC(3464)
Additional Keywords : Angiogenesis Inhibitors, Anti-Inflammatory Agents, Anti-metastatic, Apoptotic, NF-kappaB Inhibitor, prostate cancer, Vitamin K2 : CK(16) : AC(6)

Withaferin A directly inhibits the proliferation and metastatic activity of gastric cancer cells.

Article Published Date : Jun 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Ashwagandha : CK(748) : AC(301)
Diseases : Gastric Cancer : CK(1619) : AC(725)
Pharmacological Actions : Anti-metastatic : CK(2870) : AC(2182), Antiproliferative : CK(10001) : AC(7491), Apoptotic : CK(9585) : AC(7379), Cell cycle arrest : CK(2120) : AC(1715)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(75) : AC(61), Apoptotic, Ashwagandha, Cell cycle arrest, gastric cancer

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