Results for Anti-metastatic

A comprehensive review on anticancer mechanisms of crocin.

Article Published Date : Jul 02, 2017
Study Type : Review
Additional Links
Substances : Crocin : CK(391) : AC(184)
Diseases : Cancers: All : CK(28241) : AC(10590)
Pharmacological Actions : Anti-metastatic : CK(1972) : AC(1481), Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304), Chemotherapeutic : CK(2328) : AC(1086), Telomerase Inhibitor : CK(95) : AC(62)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(65) : AC(52), Apoptotic, Cancers: All, Chemotherapeutic, Crocin, Telomerase Inhibitor

A polysaccharide from Punica granatum has an inhibitory effect on metastasis.

Article Published Date : May 24, 2017
Study Type : Animal Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Cancer Metastasis : CK(798) : AC(431), Lung Cancer: Metastatic : CK(50) : AC(20)
Pharmacological Actions : Anti-metastatic : CK(1972) : AC(1481)
Additional Keywords : Anti-metastatic, Cancer Metastasis, Lung Cancer: Metastatic, pomegranate

A review of the multiple targets and signalling pathways of ginsenosides in cancers.

Article Published Date : Dec 31, 2015
Study Type : Review
Additional Links
Substances : Ginsenosides : CK(1550) : AC(873)
Diseases : Cancers: All : CK(28241) : AC(10590)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Anti-metastatic : CK(1972) : AC(1481), Antiproliferative : CK(6801) : AC(5032), Cell cycle arrest : CK(1678) : AC(1348)
Additional Keywords : Anti-Inflammatory Agents, Anti-metastatic, Antiproliferative : CK(65) : AC(52), Cancers: All, Cell cycle arrest, Ginsenosides

An extract of Litchi seed has potential for development into a safe and potent alternative therapy for prostate cancer patients.

Article Published Date : Jan 29, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Litchi : CK(29) : AC(17)
Diseases : Prostate Cancer : CK(2407) : AC(834)
Pharmacological Actions : Anti-metastatic : CK(1972) : AC(1481), Apoptotic : CK(6986) : AC(5304), Cell cycle arrest : CK(1678) : AC(1348), P21 Activation : CK(160) : AC(119)
Additional Keywords : Anti-metastatic, Apoptotic, Cell cycle arrest, Litchi, P21 Activation, Plant Extracts : CK(14140) : AC(5210), prostate cancer

Curcumin exerts its tumor suppressive function via inhibition of NEDD4 oncoprotein in glioma cancer cells.

Article Published Date : Jun 07, 2017
Study Type : In Vitro Study
Additional Links
Substances : Curcumin : CK(5598) : AC(2788)
Diseases : Glioma : CK(588) : AC(251)
Pharmacological Actions : Anti-metastatic : CK(1972) : AC(1481), Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(65) : AC(52), Apoptotic, CURCUMIN : CK(2) : AC(1), Glioma

Delta-tocotrienol inhibits pancreatic cancer stem-like cells and prevents pancreatic cancer metastasis.

Article Published Date : May 08, 2017
Study Type : In Vitro Study
Additional Links
Substances : Tocotrienol: Delta : CK(59) : AC(29), Vitamin E : CK(2533) : AC(483)
Diseases : Pancreatic Cancer : CK(1307) : AC(451)
Pharmacological Actions : Anti-metastatic : CK(1972) : AC(1481), Antiproliferative : CK(6801) : AC(5032), Chemopreventive : CK(5374) : AC(1717)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(65) : AC(52), Cancer Stem Cells : CK(375) : AC(276), Chemopreventive, Pancreatic Cancer : CK(1) : AC(1), Tocotrienol: Delta, VITAMIN E

Garcinone E exerts anticancer activities by inducing apoptosis and suppressing migration and invasion in ovarian cancer cells.

Article Published Date : Sep 05, 2017
Study Type : In Vitro Study
Additional Links
Substances : Garcinia Mangostana : CK(9) : AC(1)
Diseases : Ovarian Cancer : CK(827) : AC(371)
Pharmacological Actions : Anti-metastatic : CK(1972) : AC(1481), Apoptotic : CK(6986) : AC(5304), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(727) : AC(442), Matrix metalloproteinase-9 (MMP-9) inhibitor : CK(786) : AC(505)
Additional Keywords : Anti-metastatic, Apoptotic, Garcinia Mangostana, ovarian cancer

Genistein inhibits the growth and regulates the migration and invasion abilities of melanoma.

Article Published Date : Mar 27, 2017
Study Type : In Vitro Study
Additional Links
Substances : Genistein : CK(788) : AC(365)
Diseases : Melanoma : CK(733) : AC(408)
Pharmacological Actions : Anti-metastatic : CK(1972) : AC(1481)
Additional Keywords : Anti-metastatic, Genistein, melanoma

Ginsenoside Rb1 may be a potential therapeutic candidate for the treatment of ovarian cancer.

Article Published Date : Sep 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Ginsenosides : CK(1550) : AC(873)
Diseases : Ovarian Cancer : CK(827) : AC(371)
Pharmacological Actions : Anti-metastatic : CK(1972) : AC(1481)
Additional Keywords : Anti-metastatic, Ginsenosides, ovarian cancer

Hesperidin inhibited the migratory and invasive capabilities of A549 human non-small cell lung cancer cells.

Article Published Date : Mar 27, 2018
Study Type : In Vitro Study
Additional Links
Substances : Hesperidin : CK(545) : AC(215)
Diseases : Non-Small-Cell Lung Carcinoma : CK(70) : AC(50)
Pharmacological Actions : Anti-metastatic : CK(1972) : AC(1481), Matrix metalloproteinase-9 (MMP-9) inhibitor : CK(786) : AC(505)
Additional Keywords : Anti-metastatic, Hesperidin, Matrix metalloproteinase-9 (MMP-9) inhibitor, Non-Small-Cell Lung Carcinoma

Increase in motility and invasiveness of MCF7 cancer cells induced by nicotine is abolished by melatonin.

Article Published Date : Jan 15, 2018
Study Type : In Vitro Study
Additional Links
Substances : Melatonin : CK(1911) : AC(647)
Diseases : Breast Cancer : CK(6327) : AC(2272), Nicotine/Tobacco Toxicity : CK(242) : AC(90)
Pharmacological Actions : Anti-metastatic : CK(1972) : AC(1481)
Additional Keywords : Anti-metastatic, Breast Cancer : CK(113) : AC(34), melatonin, Nicotine/Tobacco Toxicity

Puerarin can inhibit the adhesion, invasion and migration of oophoroma HO-8910 cells.

Article Published Date : Jun 30, 2009
Study Type : In Vitro Study
Additional Links
Substances : Puerarin : CK(547) : AC(270)
Diseases : Cancer Metastasis : CK(798) : AC(431), Ovarian Cancer : CK(827) : AC(371)
Pharmacological Actions : Anti-metastatic : CK(1972) : AC(1481)
Additional Keywords : Anti-metastatic, Cancer Metastasis, ovarian cancer, Puerarin

Resveratrol prevents endothelial cells injury in high-dose interleukin-2 therapy against melanoma.

Article Published Date : Dec 31, 2011
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol : CK(2037) : AC(1112)
Diseases : Lung Cancer : CK(2308) : AC(999), Melanoma : CK(733) : AC(408)
Pharmacological Actions : Anti-metastatic : CK(1972) : AC(1481), Chemoprotective Agents : CK(2322) : AC(906), Chemosensitizer : CK(1124) : AC(854)
Additional Keywords : Anti-metastatic, Chemoprotective Agents, Chemosensitizer, lung cancer, melanoma, RESVERATROL

Shikonin and temozolomide may constitute a powerful new tool for Glioblastoma treatment by reducing therapy resistance and tumor recurrence.

Article Published Date : Apr 10, 2017
Study Type : Human In Vitro
Additional Links
Substances : Shikonin : CK(108) : AC(63)
Diseases : Glioblastoma : CK(545) : AC(272)
Pharmacological Actions : Anti-metastatic : CK(1972) : AC(1481), Antiproliferative : CK(6801) : AC(5032), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(727) : AC(442), Matrix metalloproteinase-9 (MMP-9) inhibitor : CK(786) : AC(505)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(65) : AC(52), Chemotherapeutic Synergy: Temozolomide : CK(48) : AC(35), Glioblastoma, Shikonin

The cytotoxic effects of the Stanley and Fortress onion varieties were strongest among the selected cultivars.

Article Published Date : May 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Onion : CK(420) : AC(124)
Diseases : Colorectal Cancer : CK(3666) : AC(1651)
Pharmacological Actions : Anti-metastatic : CK(1972) : AC(1481), Antiproliferative : CK(6801) : AC(5032)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(65) : AC(52), COLORECTAL CANCER, Cultivars : CK(3) : AC(3), Onion

These findings provide new insights into the antimetastatic mechanism of baicalein.

Article Published Date : Nov 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Baicalein : CK(184) : AC(112)
Diseases : Breast Cancer: Triple Negative : CK(708) : AC(466)
Pharmacological Actions : Anti-metastatic : CK(1972) : AC(1481)
Additional Keywords : Anti-metastatic, Baicalein, Breast Cancer: Triple Negative

These findings suggested that betulinic acid might be a potential agent for inhibiting the growth and metastasis of breast cancer.

Article Published Date : Jan 08, 2018
Study Type : In Vitro Study
Additional Links
Substances : Betulinic acid : CK(28) : AC(18)
Diseases : Breast Cancer : CK(6327) : AC(2272)
Pharmacological Actions : Anti-metastatic : CK(1972) : AC(1481), Matrix metalloproteinase-9 (MMP-9) inhibitor : CK(786) : AC(505)
Additional Keywords : Anti-metastatic, Betulinic acid, Breast Cancer : CK(113) : AC(34), Matrix metalloproteinase-9 (MMP-9) inhibitor

This is the first report suggesting selective anti-proliferative and anti-metastatic attributes of papaya leaf juice extract against prostatic diseases.

Article Published Date : Feb 25, 2017
Study Type : In Vitro Study
Additional Links
Substances : Papaya : CK(211) : AC(76)
Diseases : Prostate Cancer : CK(2407) : AC(834), Prostatic Hyperplasia: Benign : CK(431) : AC(106)
Pharmacological Actions : Anti-metastatic : CK(1972) : AC(1481), Antiproliferative : CK(6801) : AC(5032)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(65) : AC(52), Papaya, prostate cancer, Prostatic Hyperplasia: Benign, Selective Antiproliferation : CK(35) : AC(29)

This study demonstrates the anti-metastatic and anti-EMT activities of Antrodia camphorate.

Article Published Date : Aug 16, 2017
Study Type : In Vitro Study
Additional Links
Substances : Antrodia camphorata : CK(52) : AC(33)
Diseases : Colon Cancer : CK(1493) : AC(954)
Pharmacological Actions : Anti-metastatic : CK(1972) : AC(1481), Antineoplastic Agents : CK(1847) : AC(1170), Antiproliferative : CK(6801) : AC(5032), Chemopreventive : CK(5374) : AC(1717)
Additional Keywords : Anti-metastatic, Antineoplastic Agents : CK(78) : AC(35), Antiproliferative : CK(65) : AC(52), Antrodia camphorata, Chemopreventive, COLON CANCER

Thymoquinone inhibits the migration and invasion of cervical cancer cells.

Article Published Date : Dec 03, 2017
Study Type : In Vitro Study
Additional Links
Substances : Thymoquinone : CK(774) : AC(451)
Diseases : Cervical Cancer : CK(756) : AC(422)
Pharmacological Actions : Anti-metastatic : CK(1972) : AC(1481)
Additional Keywords : Anti-metastatic, Cervical Cancer, thymoquinone

Vitamin K2 may be a potential therapeutic agent in the treatment of prostate cancer.

Article Published Date : Dec 31, 2012
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Vitamin K2 : CK(462) : AC(74)
Diseases : Prostate Cancer : CK(2407) : AC(834)
Pharmacological Actions : Angiogenesis Inhibitors : CK(488) : AC(296), Anti-Inflammatory Agents : CK(20859) : AC(8334), Anti-metastatic : CK(1972) : AC(1481), Apoptotic : CK(6986) : AC(5304), NF-kappaB Inhibitor : CK(3536) : AC(2098)
Additional Keywords : Angiogenesis Inhibitors, Anti-Inflammatory Agents, Anti-metastatic, Apoptotic, NF-kappaB Inhibitor, prostate cancer, Vitamin K2 : CK(1) : AC(1)

Withaferin A directly inhibits the proliferation and metastatic activity of gastric cancer cells.

Article Published Date : Jun 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Ashwagandha : CK(418) : AC(173)
Diseases : Gastric Cancer : CK(1165) : AC(504)
Pharmacological Actions : Anti-metastatic : CK(1972) : AC(1481), Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304), Cell cycle arrest : CK(1678) : AC(1348)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(65) : AC(52), Apoptotic, Ashwagandha, Cell cycle arrest, gastric cancer

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