Results for Baicalein

Baicalein could be a lead compound for the modulation of inflammatory diseases as well as certain cancers.

Article Published Date : Oct 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Baicalein : CK(184) : AC(112)
Diseases : Cervical Cancer : CK(756) : AC(422), Inflammation : CK(9572) : AC(3089)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), NF-kappaB Inhibitor : CK(3536) : AC(2098), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(6736) : AC(2815)
Additional Keywords : Anti-Inflammatory Agents, Baicalein, Cervical Cancer, Gene Expression Regulation : CK(1141) : AC(501), NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Baicalein could be developed into a novel drug for clinical treatment of ICH and ICH-related brain injuries.

Article Published Date : Jan 20, 2017
Study Type : Animal Study
Additional Links
Substances : Baicalein : CK(184) : AC(112)
Diseases : Intracerebral Hemorrhage : CK(214) : AC(28)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Interleukin-4 downregulation : CK(355) : AC(128), Interleukin-6 Downregulation : CK(5029) : AC(1994), Neuroprotective Agents : CK(10404) : AC(4396), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(6736) : AC(2815)
Additional Keywords : Anti-Inflammatory Agents, Baicalein, Interleukin-4 downregulation, Intracerebral Hemorrhage

Baicalein could be used as a cytoprotective and anti-ulcerogenic agent in gastric ulcers.

Article Published Date : Oct 21, 2016
Study Type : Animal Study
Additional Links
Substances : Baicalein : CK(184) : AC(112)
Diseases : Gastric Ulcers
Pharmacological Actions : Anti-Ulcer Agents : CK(523) : AC(184), Prophylactic Agents : CK(780) : AC(182)
Additional Keywords : Anti-Ulcer Agents, Baicalein, Gastric Ulcers : CK(2) : AC(0), Prophylactic Agents

Baicalein has a protective effect of on muscle cells.

Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Baicalein : CK(184) : AC(112)
Diseases : Sarcopenia : CK(176) : AC(35)
Pharmacological Actions : Angiogenesis Inducing Agents : CK(88) : AC(45)
Additional Keywords : Angiogenesis Inducing Agents, Baicalein, Ovariectomy-Induced Changes : CK(299) : AC(126), Sarcopenia

Baicalein induces Beclin 1- and ERK-dependent autophagy in ovarian cancer cells.

Article Published Date : Jan 12, 2017
Study Type : In Vitro Study
Additional Links
Substances : Baicalein : CK(184) : AC(112)
Diseases : Ovarian Cancer : CK(827) : AC(371)
Pharmacological Actions : Autophagy Up-regulation : CK(518) : AC(349)
Additional Keywords : Autophagy Up-regulation, Baicalein, ovarian cancer

Baicalein induces cancer cell apoptosis and cause cell cycle arrest.

Article Published Date : Jul 31, 2016
Study Type : Review
Additional Links
Substances : Baicalein : CK(184) : AC(112)
Diseases : Cancers: All : CK(28241) : AC(10590)
Pharmacological Actions : Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304), Cell cycle arrest : CK(1678) : AC(1348)
Additional Keywords : Antiproliferative : CK(65) : AC(52), Apoptotic, Baicalein, Cancer : CK(50) : AC(12), Cell cycle arrest

Baicalein is a candidate drug with great potential for the treatment of AD patients.

Article Published Date : Jan 17, 2017
Study Type : In Vitro Study
Additional Links
Substances : Baicalein : CK(184) : AC(112)
Diseases : Alzheimer's Disease : CK(3372) : AC(1307)
Pharmacological Actions : Neuroprotective Agents : CK(10404) : AC(4396)
Additional Keywords : Alzheimer's disease, Baicalein, Neuroprotective Agents

Baicalein may contribute to dental pulp repair and regenerative endodontics.

Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Baicalein : CK(184) : AC(112)
Diseases : Dental Diseases : CK(29) : AC(9)
Pharmacological Actions : Angiogenesis Inducing Agents : CK(88) : AC(45), Regenerative : CK(408) : AC(172)
Additional Keywords : Angiogenesis Inducing Agents, Baicalein, Dental Diseases, Regenerative

Baicalein might be an alternative treatment against refractory chronic inflammation.

Article Published Date : Nov 25, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Baicalein : CK(184) : AC(112)
Diseases : Inflammation : CK(9572) : AC(3089)
Pharmacological Actions : Angiogenesis Inhibitors : CK(488) : AC(296), Anti-Inflammatory Agents : CK(20859) : AC(8334)
Additional Keywords : Angiogenesis Inhibitors, Anti-Inflammatory Agents, Baicalein, Inflammation : CK(128) : AC(57)

Baicalein protects against oxidized LDL induced oxidative stress and inflammation.

Article Published Date : Oct 19, 2016
Study Type : In Vitro Study
Additional Links
Substances : Baicalein : CK(184) : AC(112)
Diseases : Atherosclerosis : CK(1390) : AC(487), Cholesterol: Oxidation : CK(599) : AC(140)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856)
Additional Keywords : Anti-Inflammatory Agents, Antioxidants : CK(303) : AC(126), Atherosclerosis : CK(1) : AC(1), Baicalein, Cholesterol: Oxidation

Baicalein protects against UVB-induced oxidative stress via scavenging ROS, inhibiting apoptosis, and absorbing UV photons.

Article Published Date : Oct 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Baicalein : CK(184) : AC(112)
Diseases : Oxidative Stress : CK(9437) : AC(3550), Ultraviolet Radiation Induced Damage : CK(461) : AC(215)
Pharmacological Actions : Anti-Apoptotic : CK(2905) : AC(1672), Photoprotective : CK(446) : AC(198)
Additional Keywords : Baicalein, oxidative stress, Ultraviolet Radiation Induced Damage

Baicalein significantly improved the biochemical and histopathological condition of Alzheimer's disease in rats.

Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Baicalein : CK(184) : AC(112)
Diseases : Alzheimer's Disease : CK(3372) : AC(1307)
Pharmacological Actions : Neuroprotective Agents : CK(10404) : AC(4396)
Additional Keywords : Alzheimer's disease, Baicalein, Dose Response : CK(1712) : AC(683), Neuroprotective Agents

These findings provide new insights into the antimetastatic mechanism of baicalein.

Article Published Date : Nov 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Baicalein : CK(184) : AC(112)
Diseases : Breast Cancer: Triple Negative : CK(708) : AC(466)
Pharmacological Actions : Anti-metastatic : CK(1972) : AC(1481)
Additional Keywords : Anti-metastatic, Baicalein, Breast Cancer: Triple Negative

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