Results for Baicalein

Baicalein could be a lead compound for the modulation of inflammatory diseases as well as certain cancers.

Article Published Date : Oct 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Baicalein : CK(312) : AC(202)
Diseases : Cervical Cancer : CK(975) : AC(595), Inflammation : CK(16094) : AC(5496)
Pharmacological Actions : Anti-Inflammatory Agents : CK(39737) : AC(15858), NF-kappaB Inhibitor : CK(5952) : AC(3464), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(11697) : AC(4806)
Additional Keywords : Anti-Inflammatory Agents, Baicalein, Cervical Cancer, Gene Expression Regulation : CK(1401) : AC(623), NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Baicalein could be developed into a novel drug for clinical treatment of ICH and ICH-related brain injuries.

Article Published Date : Jan 20, 2017
Study Type : Animal Study
Additional Links
Substances : Baicalein : CK(312) : AC(202)
Diseases : Intracerebral Hemorrhage : CK(292) : AC(54)
Pharmacological Actions : Anti-Inflammatory Agents : CK(39737) : AC(15858), Interleukin-4 downregulation : CK(460) : AC(173), Interleukin-6 Downregulation : CK(9337) : AC(3613), Neuroprotective Agents : CK(20061) : AC(7949), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(11697) : AC(4806)
Additional Keywords : Anti-Inflammatory Agents, Baicalein, Interleukin-4 downregulation, Intracerebral Hemorrhage

Baicalein could be used as a cytoprotective and anti-ulcerogenic agent in gastric ulcers.

Article Published Date : Oct 21, 2016
Study Type : Animal Study
Additional Links
Substances : Baicalein : CK(312) : AC(202)
Diseases : Gastric Ulcers
Pharmacological Actions : Anti-Ulcer Agents : CK(1250) : AC(341), Prophylactic Agents : CK(1700) : AC(335)
Additional Keywords : Anti-Ulcer Agents, Baicalein, Gastric Ulcers : CK(2) : AC(1), Prophylactic Agents

Baicalein has a protective effect of on muscle cells.

Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Baicalein : CK(312) : AC(202)
Diseases : Sarcopenia : CK(368) : AC(79)
Pharmacological Actions : Angiogenesis Inducing Agents : CK(290) : AC(149)
Additional Keywords : Angiogenesis Inducing Agents, Baicalein, Ovariectomy-Induced Changes : CK(395) : AC(175), Sarcopenia

Baicalein induces Beclin 1- and ERK-dependent autophagy in ovarian cancer cells.

Article Published Date : Jan 12, 2017
Study Type : In Vitro Study
Additional Links
Substances : Baicalein : CK(312) : AC(202)
Diseases : Ovarian Cancer : CK(1029) : AC(509)
Pharmacological Actions : Autophagy Up-regulation : CK(838) : AC(559)
Additional Keywords : Autophagy Up-regulation, Baicalein, ovarian cancer

Baicalein induces cancer cell apoptosis and cause cell cycle arrest.

Article Published Date : Jul 31, 2016
Study Type : Review
Additional Links
Substances : Baicalein : CK(312) : AC(202)
Diseases : Cancers: All : CK(36404) : AC(14363)
Pharmacological Actions : Antiproliferative : CK(10001) : AC(7491), Apoptotic : CK(9585) : AC(7379), Cell cycle arrest : CK(2120) : AC(1715)
Additional Keywords : Antiproliferative : CK(75) : AC(61), Apoptotic, Baicalein, Cancer : CK(50) : AC(12), Cell cycle arrest

Baicalein is a candidate drug with great potential for the treatment of AD patients.

Article Published Date : Jan 17, 2017
Study Type : In Vitro Study
Additional Links
Substances : Baicalein : CK(312) : AC(202)
Diseases : Alzheimer's Disease : CK(5355) : AC(2210)
Pharmacological Actions : Neuroprotective Agents : CK(20061) : AC(7949)
Additional Keywords : Alzheimer's disease, Baicalein, Neuroprotective Agents

Baicalein may contribute to dental pulp repair and regenerative endodontics.

Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Baicalein : CK(312) : AC(202)
Diseases : Dental Diseases : CK(31) : AC(10)
Pharmacological Actions : Angiogenesis Inducing Agents : CK(290) : AC(149), Regenerative : CK(486) : AC(201)
Additional Keywords : Angiogenesis Inducing Agents, Baicalein, Dental Diseases, Regenerative

Baicalein might be an alternative treatment against refractory chronic inflammation.

Article Published Date : Nov 25, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Baicalein : CK(312) : AC(202)
Diseases : Inflammation : CK(16094) : AC(5496)
Pharmacological Actions : Angiogenesis Inhibitors : CK(724) : AC(481), Anti-Inflammatory Agents : CK(39737) : AC(15858)
Additional Keywords : Angiogenesis Inhibitors, Anti-Inflammatory Agents, Baicalein, Inflammation : CK(128) : AC(57)

Baicalein protects against oxidized LDL induced oxidative stress and inflammation.

Article Published Date : Oct 19, 2016
Study Type : In Vitro Study
Additional Links
Substances : Baicalein : CK(312) : AC(202)
Diseases : Atherosclerosis : CK(2063) : AC(778), Cholesterol: Oxidation : CK(654) : AC(159)
Pharmacological Actions : Anti-Inflammatory Agents : CK(39737) : AC(15858), Antioxidants : CK(34551) : AC(14499)
Additional Keywords : Anti-Inflammatory Agents, Antioxidants : CK(303) : AC(126), Atherosclerosis : CK(32) : AC(10), Baicalein, Cholesterol: Oxidation

Baicalein protects against UVB-induced oxidative stress via scavenging ROS, inhibiting apoptosis, and absorbing UV photons.

Article Published Date : Oct 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Baicalein : CK(312) : AC(202)
Diseases : Oxidative Stress : CK(14758) : AC(5716), Ultraviolet Radiation Induced Damage : CK(788) : AC(332)
Pharmacological Actions : Anti-Apoptotic : CK(5568) : AC(3160), Photoprotective : CK(778) : AC(304)
Additional Keywords : Baicalein, oxidative stress, Ultraviolet Radiation Induced Damage

Baicalein significantly improved the biochemical and histopathological condition of Alzheimer's disease in rats.

Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Baicalein : CK(312) : AC(202)
Diseases : Alzheimer's Disease : CK(5355) : AC(2210)
Pharmacological Actions : Neuroprotective Agents : CK(20061) : AC(7949)
Additional Keywords : Alzheimer's disease, Baicalein, Dose Response : CK(1770) : AC(700), Neuroprotective Agents

These findings provide new insights into the antimetastatic mechanism of baicalein.

Article Published Date : Nov 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Baicalein : CK(312) : AC(202)
Diseases : Breast Cancer: Triple Negative : CK(970) : AC(659)
Pharmacological Actions : Anti-metastatic : CK(2870) : AC(2182)
Additional Keywords : Anti-metastatic, Baicalein, Breast Cancer: Triple Negative

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