Results for Bcl-2 protein down-regulation

An extract of Lotus may be a powerful agent against colon cancer cells.

Article Published Date : Feb 28, 2017
Study Type : In Vitro Study
Additional Links
Substances : Lotus : CK(398) : AC(258)
Diseases : Colon Cancer : CK(1903) : AC(1192)
Pharmacological Actions : Apoptotic : CK(9480) : AC(7298), Bcl-2 protein down-regulation : CK(704) : AC(524), Bcl-xL down-regulation : CK(41) : AC(30), Cyclooxygenase 2 Inhibitors : CK(2184) : AC(1284), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(936) : AC(583), Matrix metalloproteinase-9 (MMP-9) inhibitor : CK(1118) : AC(706), NF-kappaB Inhibitor : CK(5828) : AC(3391)
Additional Keywords : Apoptotic, Bcl-2 protein down-regulation, COLON CANCER, Lotus, Plant Extracts : CK(18617) : AC(6734)

Carnosic acid cooperates with tamoxifen to induce apoptosis in breast cancer cells.

Article Published Date : Apr 30, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Carnosic Acid : CK(165) : AC(111)
Diseases : Breast Cancer : CK(8185) : AC(3005)
Pharmacological Actions : Apoptotic : CK(9480) : AC(7298), Bcl-2 protein down-regulation : CK(704) : AC(524), Bcl-xL down-regulation : CK(41) : AC(30)
Additional Keywords : Apoptotic, Bcl-2 protein down-regulation, Bcl-xL down-regulation, Breast Cancer : CK(113) : AC(34), Carnosic Acid, Synergy with Tamoxifen : CK(32) : AC(26)
Problem Substances : Tamoxifen : CK(401) : AC(68)

Ganoderma lucidum triterpenes induce apoptosis in MCF-7 cells and attenuate DMBA induced mammary and skin carcinomas.

Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Reishi Mushroom : CK(650) : AC(349)
Diseases : Breast Cancer : CK(8185) : AC(3005), Skin Cancer : CK(1725) : AC(822)
Pharmacological Actions : Anticarcinogenic Agents : CK(2134) : AC(1011), Apoptotic : CK(9480) : AC(7298), Bcl-2 protein down-regulation : CK(704) : AC(524), Bcl-xL down-regulation : CK(41) : AC(30), Chemopreventive : CK(6496) : AC(2135), Cyclin D1 Down-Regulation : CK(139) : AC(103)
Additional Keywords : Anticarcinogenic Agents, Apoptotic, Bcl-2 protein down-regulation, Bcl-xL down-regulation, Breast Cancer : CK(113) : AC(34), Chemopreventive, Cyclin D1 Down-Regulation, Reishi Mushroom, skin cancer

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