Results for Bcl-2 protein down-regulation

An extract of Lotus may be a powerful agent against colon cancer cells.

Article Published Date : Feb 28, 2017
Study Type : In Vitro Study
Additional Links
Substances : Lotus : CK(522) : AC(325)
Diseases : Colon Cancer : CK(1989) : AC(1248)
Pharmacological Actions : Apoptotic : CK(10593) : AC(8189), Bcl-2 protein down-regulation : CK(786) : AC(583), Bcl-xL down-regulation : CK(41) : AC(30), Cyclooxygenase 2 Inhibitors : CK(2433) : AC(1429), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(1018) : AC(637), Matrix metalloproteinase-9 (MMP-9) inhibitor : CK(1242) : AC(783), NF-kappaB Inhibitor : CK(6728) : AC(3903)
Additional Keywords : Apoptotic, Bcl-2 protein down-regulation, COLON CANCER, Lotus, Plant Extracts : CK(19928) : AC(7324)

Carnosic acid cooperates with tamoxifen to induce apoptosis in breast cancer cells.

Article Published Date : Apr 30, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Carnosic Acid : CK(167) : AC(112)
Diseases : Breast Cancer : CK(8603) : AC(3216)
Pharmacological Actions : Apoptotic : CK(10593) : AC(8189), Bcl-2 protein down-regulation : CK(786) : AC(583), Bcl-xL down-regulation : CK(41) : AC(30)
Additional Keywords : Apoptotic, Bcl-2 protein down-regulation, Bcl-xL down-regulation, Breast Cancer : CK(113) : AC(34), Carnosic Acid, Synergy with Tamoxifen : CK(38) : AC(31)
Problem Substances : Tamoxifen : CK(401) : AC(68)

Ganoderma lucidum triterpenes induce apoptosis in MCF-7 cells and attenuate DMBA induced mammary and skin carcinomas.

Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Reishi Mushroom : CK(670) : AC(358)
Diseases : Breast Cancer : CK(8603) : AC(3216), Skin Cancer : CK(1904) : AC(890)
Pharmacological Actions : Anticarcinogenic Agents : CK(2163) : AC(1025), Apoptotic : CK(10593) : AC(8189), Bcl-2 protein down-regulation : CK(786) : AC(583), Bcl-xL down-regulation : CK(41) : AC(30), Chemopreventive : CK(6697) : AC(2227), Cyclin D1 Down-Regulation : CK(156) : AC(115)
Additional Keywords : Anticarcinogenic Agents, Apoptotic, Bcl-2 protein down-regulation, Bcl-xL down-regulation, Breast Cancer : CK(113) : AC(34), Chemopreventive, Cyclin D1 Down-Regulation, Reishi Mushroom, skin cancer

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