Results for Bcl-2 protein down-regulation

An extract of Lotus may be a powerful agent against colon cancer cells.

Article Published Date : Feb 28, 2017
Study Type : In Vitro Study
Additional Links
Substances : Lotus : CK(398) : AC(258)
Diseases : Colon Cancer : CK(1942) : AC(1215)
Pharmacological Actions : Apoptotic : CK(9816) : AC(7572), Bcl-2 protein down-regulation : CK(723) : AC(534), Bcl-xL down-regulation : CK(41) : AC(30), Cyclooxygenase 2 Inhibitors : CK(2309) : AC(1355), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(956) : AC(596), Matrix metalloproteinase-9 (MMP-9) inhibitor : CK(1175) : AC(736), NF-kappaB Inhibitor : CK(6153) : AC(3581)
Additional Keywords : Apoptotic, Bcl-2 protein down-regulation, COLON CANCER, Lotus, Plant Extracts : CK(19049) : AC(6978)

Carnosic acid cooperates with tamoxifen to induce apoptosis in breast cancer cells.

Article Published Date : Apr 30, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Carnosic Acid : CK(167) : AC(112)
Diseases : Breast Cancer : CK(8442) : AC(3107)
Pharmacological Actions : Apoptotic : CK(9816) : AC(7572), Bcl-2 protein down-regulation : CK(723) : AC(534), Bcl-xL down-regulation : CK(41) : AC(30)
Additional Keywords : Apoptotic, Bcl-2 protein down-regulation, Bcl-xL down-regulation, Breast Cancer : CK(113) : AC(34), Carnosic Acid, Synergy with Tamoxifen : CK(36) : AC(29)
Problem Substances : Tamoxifen : CK(401) : AC(68)

Ganoderma lucidum triterpenes induce apoptosis in MCF-7 cells and attenuate DMBA induced mammary and skin carcinomas.

Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Reishi Mushroom : CK(651) : AC(350)
Diseases : Breast Cancer : CK(8442) : AC(3107), Skin Cancer : CK(1843) : AC(849)
Pharmacological Actions : Anticarcinogenic Agents : CK(2153) : AC(1019), Apoptotic : CK(9816) : AC(7572), Bcl-2 protein down-regulation : CK(723) : AC(534), Bcl-xL down-regulation : CK(41) : AC(30), Chemopreventive : CK(6642) : AC(2196), Cyclin D1 Down-Regulation : CK(146) : AC(107)
Additional Keywords : Anticarcinogenic Agents, Apoptotic, Bcl-2 protein down-regulation, Bcl-xL down-regulation, Breast Cancer : CK(113) : AC(34), Chemopreventive, Cyclin D1 Down-Regulation, Reishi Mushroom, skin cancer

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