Results for Bcl-2 protein down-regulation

An extract of Lotus may be a powerful agent against colon cancer cells.

Article Published Date : Feb 28, 2017
Study Type : In Vitro Study
Additional Links
Substances : Lotus : CK(237) : AC(170)
Diseases : Colon Cancer : CK(1493) : AC(954)
Pharmacological Actions : Apoptotic : CK(6986) : AC(5304), Bcl-2 protein down-regulation : CK(553) : AC(407), Bcl-xL down-regulation : CK(35) : AC(26), Cyclooxygenase 2 Inhibitors : CK(1589) : AC(926), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(727) : AC(442), Matrix metalloproteinase-9 (MMP-9) inhibitor : CK(786) : AC(505), NF-kappaB Inhibitor : CK(3536) : AC(2098)
Additional Keywords : Apoptotic, Bcl-2 protein down-regulation, COLON CANCER, Lotus, Plant Extracts : CK(14140) : AC(5210)

Carnosic acid cooperates with tamoxifen to induce apoptosis in breast cancer cells.

Article Published Date : Apr 30, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Carnosic Acid : CK(121) : AC(82)
Diseases : Breast Cancer : CK(6327) : AC(2272)
Pharmacological Actions : Apoptotic : CK(6986) : AC(5304), Bcl-2 protein down-regulation : CK(553) : AC(407), Bcl-xL down-regulation : CK(35) : AC(26)
Additional Keywords : Apoptotic, Bcl-2 protein down-regulation, Bcl-xL down-regulation, Breast Cancer : CK(113) : AC(34), Carnosic Acid, Synergy with Tamoxifen : CK(6) : AC(5)
Problem Substances : Tamoxifen : CK(401) : AC(68)

Ganoderma lucidum triterpenes induce apoptosis in MCF-7 cells and attenuate DMBA induced mammary and skin carcinomas.

Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Reishi Mushroom : CK(406) : AC(202)
Diseases : Breast Cancer : CK(6327) : AC(2272), Skin Cancer : CK(1429) : AC(636)
Pharmacological Actions : Anticarcinogenic Agents : CK(1890) : AC(889), Apoptotic : CK(6986) : AC(5304), Bcl-2 protein down-regulation : CK(553) : AC(407), Bcl-xL down-regulation : CK(35) : AC(26), Chemopreventive : CK(5374) : AC(1717), Cyclin D1 Down-Regulation : CK(106) : AC(79)
Additional Keywords : Anticarcinogenic Agents, Apoptotic, Bcl-2 protein down-regulation, Bcl-xL down-regulation, Breast Cancer : CK(113) : AC(34), Chemopreventive, Cyclin D1 Down-Regulation, Reishi Mushroom, skin cancer

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