Results for Bloodroot

Sanguinarine as a potent inhibitor of dihydrofolate reductase, able to impair enzyme activity even in methotrexate resistant MDA-MB-231 cells.

Article Published Date : Jul 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Bloodroot : CK(37) : AC(13)
Diseases : Breast Cancer : CK(8291) : AC(3037), Breast Cancer: Drug Resistant : CK(22) : AC(14), Breast Cancer: Triple Negative : CK(970) : AC(659)
Pharmacological Actions : Antiproliferative : CK(9993) : AC(7483), Apoptotic : CK(9578) : AC(7374), Cyclin D1 Down-Regulation : CK(143) : AC(106), Enzyme Inhibitors : CK(846) : AC(399)
Additional Keywords : Bloodroot, Breast Cancer : CK(113) : AC(34), Breast Cancer: Drug Resistant, Breast Cancer: Triple Negative, Dose Response : CK(1770) : AC(700)

Sanguinarine sensitizes human gastric adenocarcinoma AGS cells to TRAIL-mediated apoptosis.

Article Published Date : Oct 31, 2009
Study Type : In Vitro Study
Additional Links
Substances : Bloodroot : CK(37) : AC(13)
Diseases : Gastric Cancer : CK(1619) : AC(725)
Pharmacological Actions : Apoptotic : CK(9578) : AC(7374), Caspase-3 Activation : CK(137) : AC(90), Chemosensitizer : CK(1656) : AC(1269)
Additional Keywords : Apoptotic, Bloodroot, Caspase-3 Activation, Chemosensitizer, gastric cancer

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