Results for Brain-derived neurotrophic factor modulator

Lotus root might potentially improve neural function through the stimulation of BDNF production in glial cells.

Article Published Date : May 08, 2017
Study Type : In Vitro Study
Additional Links
Substances : Lotus : CK(398) : AC(258)
Pharmacological Actions : Brain-derived neurotrophic factor modulator : CK(745) : AC(280), Heme oxygenase-1 up-regulation : CK(1336) : AC(776)
Additional Keywords : Brain-derived neurotrophic factor modulator, Heme oxygenase-1 up-regulation, Lotus, Plant Extracts : CK(18764) : AC(6783)

Melatonin promotes brain-derived neurotrophic factor expression and anti-apoptotic effects in neonatal hemolytic hyperbilirubinemia.

Article Published Date : Dec 15, 2017
Study Type : Animal Study
Additional Links
Substances : Melatonin : CK(2891) : AC(911)
Diseases : Hyperbilirubinemia: Hereditary : CK(39) : AC(7)
Pharmacological Actions : Anti-Apoptotic : CK(5571) : AC(3161), Brain-derived neurotrophic factor modulator : CK(745) : AC(280)
Additional Keywords : Anti-Apoptotic, Brain-derived neurotrophic factor modulator, Hyperbilirubinemia: Hereditary, melatonin

Spirulina maxima administered together with other therapeutics may induce synergistic effects to ameliorate cognitive dysfunction.

Article Published Date : Nov 12, 2017
Study Type : Animal Study
Additional Links
Substances : Spirulina : CK(1017) : AC(292)
Diseases : Alzheimer's Disease : CK(5355) : AC(2210), Memory Disorders : CK(2443) : AC(640)
Pharmacological Actions : Brain-derived neurotrophic factor modulator : CK(745) : AC(280), Neuroprotective Agents : CK(20065) : AC(7951)
Additional Keywords : Alzheimer's disease, Brain-derived neurotrophic factor modulator, Memory Disorders, Neuroprotective Agents, Spirulina

Sulforaphane improves LPS-induced spatial learning and memory dysfunction, likely by upregulating neurogenesis through the BDNF-mTOR pathway.

Article Published Date : Jan 15, 2018
Study Type : Animal Study
Additional Links
Substances : Sulforaphane : CK(1344) : AC(630)
Diseases : Inflammation : CK(16108) : AC(5498), Lipopolysaccharide-Induced Toxicity : CK(3229) : AC(1875), Memory Disorders : CK(2443) : AC(640)
Pharmacological Actions : Anti-Inflammatory Agents : CK(39739) : AC(15859), Neurogenesis : CK(325) : AC(173)
Additional Keywords : Brain-derived neurotrophic factor modulator, Broccoli : CK(89) : AC(26), Broccoli Sprouts, Cruciferous Vegetables, Isothiocyanates : CK(254) : AC(104)

The current meta-analysis supports the use of melatonin for anti-nociception.

Article Published Date : Nov 20, 2017
Study Type : Meta Analysis, Review
Additional Links
Substances : Melatonin : CK(2891) : AC(911)
Diseases : Chronic Pain : CK(1524) : AC(284)
Pharmacological Actions : Antinoceceptive : CK(959) : AC(291), Brain-derived neurotrophic factor modulator : CK(745) : AC(280)
Additional Keywords : Antinoceceptive, Brain-derived neurotrophic factor modulator, Chronic Pain, melatonin

The data support a promising therapeutic profile for CBD as a new fast-acting antidepressant treatment.

Article Published Date : Jun 03, 2018
Study Type : Animal Study
Additional Links
Substances : Cannabidiol : CK(3371) : AC(1007)
Diseases : Depression
Pharmacological Actions : Antidepressive Agents : CK(7918) : AC(1467), Brain-derived neurotrophic factor modulator : CK(745) : AC(280)
Additional Keywords : Antidepressive Agents, Brain-derived neurotrophic factor modulator, Cannabidiol, Depression : CK(108) : AC(19)

The neuroprotective effects of quercetin may be at least partly due to its inducing effects on the expression levels of the BDNF mRNA.

Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Quercetin : CK(1876) : AC(855)
Pharmacological Actions : Brain-derived neurotrophic factor modulator : CK(745) : AC(280), Neuroprotective Agents : CK(20065) : AC(7951)
Additional Keywords : Brain-derived neurotrophic factor modulator, Neuroprotective Agents, QUERCETIN

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