Results for Cell cycle arrest

A review of the multiple targets and signalling pathways of ginsenosides in cancers.

Article Published Date : Dec 31, 2015
Study Type : Review
Additional Links
Substances : Ginsenosides : CK(1024) : AC(597)
Diseases : Cancers: All : CK(22165) : AC(7896)
Pharmacological Actions : Anti-Inflammatory Agents : CK(12461) : AC(4729), Anti-metastatic : CK(1284) : AC(927), Antiproliferative : CK(4773) : AC(3450), Cell cycle arrest : CK(1289) : AC(1006)
Additional Keywords : Anti-Inflammatory Agents, Anti-metastatic, Antiproliferative : CK(65) : AC(52), Cancers: All, Cell cycle arrest, Ginsenosides

An extract of Litchi seed has potential for development into a safe and potent alternative therapy for prostate cancer patients.

Article Published Date : Jan 29, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Litchi : CK(29) : AC(17)
Diseases : Prostate Cancer : CK(2097) : AC(687)
Pharmacological Actions : Anti-metastatic : CK(1284) : AC(927), Apoptotic : CK(5217) : AC(3846), Cell cycle arrest : CK(1289) : AC(1006), P21 Activation : CK(72) : AC(47)
Additional Keywords : Anti-metastatic, Apoptotic, Cell cycle arrest, Litchi, P21 Activation, Plant Extracts : CK(11762) : AC(4236), prostate cancer

Baicalein induces cancer cell apoptosis and cause cell cycle arrest.

Article Published Date : Jul 31, 2016
Study Type : Review
Additional Links
Substances : Baicalein : CK(106) : AC(75)
Diseases : Cancers: All : CK(22165) : AC(7896)
Pharmacological Actions : Antiproliferative : CK(4773) : AC(3450), Apoptotic : CK(5217) : AC(3846), Cell cycle arrest : CK(1289) : AC(1006)
Additional Keywords : Antiproliferative : CK(65) : AC(52), Apoptotic, Baicalein, Cancer : CK(1) : AC(1), Cell cycle arrest

Caffeic acid and caffeic acid phenethyl ester induce apoptosis and cell cycle arrest of breast cancer cells MDA-MB-231.

Article Published Date : Sep 14, 2017
Study Type : In Vitro Study
Additional Links
Substances : Caffeic Acid : CK(43) : AC(25), Caffeic acid phenethyl ester : CK(58) : AC(30)
Diseases : Breast Cancer: Triple Negative : CK(551) : AC(337)
Pharmacological Actions : Antiproliferative : CK(4773) : AC(3450), Apoptotic : CK(5217) : AC(3846), Cell cycle arrest : CK(1289) : AC(1006)
Additional Keywords : Antiproliferative : CK(65) : AC(52), Apoptotic, Breast Cancer: Triple Negative, Caffeic Acid, Caffeic acid phenethyl ester, Cell cycle arrest

Cinnamon extract from Sanyangxuedai may be effective for treating leukemia.

Article Published Date : Aug 18, 2016
Study Type : In Vitro Study
Additional Links
Substances : Cinnamon : CK(394) : AC(141)
Diseases : Leukemia : CK(1284) : AC(586)
Pharmacological Actions : Antiproliferative : CK(4773) : AC(3450), Apoptotic : CK(5217) : AC(3846), Cell cycle arrest : CK(1289) : AC(1006)
Additional Keywords : Antiproliferative : CK(65) : AC(52), Apoptotic, Cell cycle arrest, cinnamon, leukemia, Plant Extracts : CK(11762) : AC(4236)

Combined use of lower concentrations of jerantinine A and γ-tocotrienol induced potent cytotoxic effects on U87MG cancer cells.

Article Published Date : Jun 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Vitamin E: Gamma-tocotrienol : CK(44) : AC(28)
Diseases : Glioblastoma : CK(398) : AC(193)
Pharmacological Actions : Antiproliferative : CK(4773) : AC(3450), Apoptotic : CK(5217) : AC(3846), Cell cycle arrest : CK(1289) : AC(1006), Chemoprotective Agents : CK(356) : AC(146), Chemosensitizer : CK(772) : AC(577), Chemotherapeutic : CK(397) : AC(152), Tumor Suppressor Protein p53 Upregulation : CK(480) : AC(343)
Additional Keywords : Antiproliferative : CK(65) : AC(52), Apoptotic, Cell cycle arrest, Glioblastoma, Natural Substance/Drug Synergy : CK(352) : AC(142), Vitamin E: Gamma-tocotrienol

Diallyl trisulfide suppresses tumor growth and potentiates cisplatin efficacy in gastric cancer treatment.

Article Published Date : Mar 26, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Dimethyl trisulfide (DMTS) : CK(8) : AC(5)
Diseases : Gastric Cancer : CK(836) : AC(341)
Pharmacological Actions : Apoptotic : CK(5217) : AC(3846), Cell cycle arrest : CK(1289) : AC(1006), Chemosensitizer : CK(772) : AC(577)
Additional Keywords : Apoptotic, Cell cycle arrest, Chemosensitizer, Chemotherapeutic Synergy: Cisplatin : CK(137) : AC(103), Dimethyl trisulfide (DMTS), gastric cancer

Ethanol extract of Antrodia camphorata inhibits proliferation of HCT-8 human colorectal cancer cells.

Article Published Date : Sep 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Antrodia camphorata : CK(32) : AC(19)
Diseases : Colorectal Cancer : CK(2874) : AC(1192)
Pharmacological Actions : Antiproliferative : CK(4773) : AC(3450), Apoptotic : CK(5217) : AC(3846), Cell cycle arrest : CK(1289) : AC(1006)
Additional Keywords : Antiproliferative : CK(65) : AC(52), Antrodia camphorata, Apoptotic, Cell cycle arrest, COLORECTAL CANCER

Harmaline induces cell cycle arrest and apoptosis in SGC-7901 cells.

Article Published Date : Dec 17, 2015
Study Type : Animal Study
Additional Links
Substances : Syrian rue : CK(1) : AC(1)
Diseases : Gastric Cancer : CK(836) : AC(341)
Pharmacological Actions : Antiproliferative : CK(4773) : AC(3450), Apoptotic : CK(5217) : AC(3846), Cell cycle arrest : CK(1289) : AC(1006)
Additional Keywords : Antiproliferative : CK(65) : AC(52), Apoptotic, Cell cycle arrest, gastric cancer, Syrian rue

Honokiol is a good candidate for further studies as a possible treatment for malignant melanoma.

Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Honokiol : CK(103) : AC(63)
Diseases : Malignant Melanoma : CK(34) : AC(16)
Pharmacological Actions : Apoptotic : CK(5217) : AC(3846), Cell cycle arrest : CK(1289) : AC(1006)
Additional Keywords : Apoptotic, Cell cycle arrest, Honokiol, Malignant Melanoma

Tangeretin may be a therapeutic agent for glioblastoma treatment.

Article Published Date : Jun 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Tangeretin : CK(38) : AC(24)
Diseases : Glioblastoma : CK(398) : AC(193)
Pharmacological Actions : Antiproliferative : CK(4773) : AC(3450), Apoptotic : CK(5217) : AC(3846), Cell cycle arrest : CK(1289) : AC(1006)
Additional Keywords : Antiproliferative : CK(65) : AC(52), Apoptotic, Cell cycle arrest, Glioblastoma, Tangeretin

Tea polyphenols induce S phase arrest and apoptosis in gallbladder cancer cells.

Article Published Date : Feb 28, 2018
Study Type : Animal Study
Additional Links
Substances : Polyphenols : CK(1353) : AC(489)
Diseases : Gallbladder Cancer : CK(65) : AC(13)
Pharmacological Actions : Antiproliferative : CK(4773) : AC(3450), Apoptotic : CK(5217) : AC(3846), Cell cycle arrest : CK(1289) : AC(1006)
Additional Keywords : Antiproliferative : CK(65) : AC(52), Apoptotic, Cell cycle arrest, Gallbladder Cancer, POLYPHENOLS : CK(1) : AC(1)

Vitamin C with decitabine activates TET2 in leukemic cells and significantly improves overall survival in elderly patients with acute myeloid leukemia.

Article Published Date : Jan 01, 2018
Study Type : In Vitro Study
Additional Links
Substances : Vitamin C : CK(3397) : AC(792), Vitamin C: Intravenous : CK(147) : AC(25)
Diseases : Acute Myeloid Leukemia : CK(162) : AC(87)
Pharmacological Actions : Antiproliferative : CK(4773) : AC(3450), Apoptotic : CK(5217) : AC(3846), Cell cycle arrest : CK(1289) : AC(1006), Chemotherapeutic : CK(397) : AC(152)
Additional Keywords : Acute Myeloid Leukemia, Antiproliferative : CK(65) : AC(52), Apoptotic, Cell cycle arrest, Chemotherapeutic, Natural Substance/Drug Synergy : CK(352) : AC(142), Vitamin C : CK(1) : AC(1), Vitamin C: Intravenous

Wasabi compounds may possess activity against the growth and cancer stem cells phenotypes of human pancreatic cancer cells.

Article Published Date : Dec 31, 2013
Study Type : In Vitro Study
Additional Links
Substances : Isothiocyanates : CK(831) : AC(407), Wasabi : CK(23) : AC(18)
Diseases : Pancreatic Cancer : CK(1127) : AC(363)
Pharmacological Actions : Apoptotic : CK(5217) : AC(3846), Cell cycle arrest : CK(1289) : AC(1006)
Additional Keywords : Apoptotic, Cancer Stem Cells : CK(274) : AC(194), Cell cycle arrest, Pancreatic Cancer : CK(1) : AC(1)

Withaferin A directly inhibits the proliferation and metastatic activity of gastric cancer cells.

Article Published Date : Jun 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Ashwagandha : CK(289) : AC(121)
Diseases : Gastric Cancer : CK(836) : AC(341)
Pharmacological Actions : Anti-metastatic : CK(1284) : AC(927), Antiproliferative : CK(4773) : AC(3450), Apoptotic : CK(5217) : AC(3846), Cell cycle arrest : CK(1289) : AC(1006)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(65) : AC(52), Apoptotic, Ashwagandha, Cell cycle arrest, gastric cancer

Xanthones from Garcinia mangostana fruit hulls were cytotoxic against cancer cell lines.

Article Published Date : Jan 16, 2017
Study Type : In Vitro Study
Additional Links
Substances : Mangosteen : CK(111) : AC(50), Xanthones : CK(13) : AC(12)
Diseases : Breast Cancer : CK(5066) : AC(1738), Colorectal Cancer : CK(2874) : AC(1192), Liver Cancer : CK(1953) : AC(852)
Pharmacological Actions : Antiproliferative : CK(4773) : AC(3450), Apoptotic : CK(5217) : AC(3846), Cell cycle arrest : CK(1289) : AC(1006)
Additional Keywords : Antiproliferative : CK(65) : AC(52), Apoptotic, Breast Cancer : CK(2) : AC(1), Cell cycle arrest, COLORECTAL CANCER, liver cancer, Mangosteen, Xanthones : CK(50) : AC(29)

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