Results for Cell cycle arrest

A review of the multiple targets and signalling pathways of ginsenosides in cancers.

Article Published Date : Dec 31, 2015
Study Type : Review
Additional Links
Substances : Ginsenosides : CK(1550) : AC(873)
Diseases : Cancers: All : CK(28241) : AC(10590)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Anti-metastatic : CK(1972) : AC(1481), Antiproliferative : CK(6801) : AC(5032), Cell cycle arrest : CK(1678) : AC(1348)
Additional Keywords : Anti-Inflammatory Agents, Anti-metastatic, Antiproliferative : CK(65) : AC(52), Cancers: All, Cell cycle arrest, Ginsenosides

An extract of Litchi seed has potential for development into a safe and potent alternative therapy for prostate cancer patients.

Article Published Date : Jan 29, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Litchi : CK(29) : AC(17)
Diseases : Prostate Cancer : CK(2407) : AC(834)
Pharmacological Actions : Anti-metastatic : CK(1972) : AC(1481), Apoptotic : CK(6986) : AC(5304), Cell cycle arrest : CK(1678) : AC(1348), P21 Activation : CK(160) : AC(119)
Additional Keywords : Anti-metastatic, Apoptotic, Cell cycle arrest, Litchi, P21 Activation, Plant Extracts : CK(14140) : AC(5210), prostate cancer

Baicalein induces cancer cell apoptosis and cause cell cycle arrest.

Article Published Date : Jul 31, 2016
Study Type : Review
Additional Links
Substances : Baicalein : CK(184) : AC(112)
Diseases : Cancers: All : CK(28241) : AC(10590)
Pharmacological Actions : Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304), Cell cycle arrest : CK(1678) : AC(1348)
Additional Keywords : Antiproliferative : CK(65) : AC(52), Apoptotic, Baicalein, Cancer : CK(50) : AC(12), Cell cycle arrest

Caffeic acid and caffeic acid phenethyl ester induce apoptosis and cell cycle arrest of breast cancer cells MDA-MB-231.

Article Published Date : Sep 14, 2017
Study Type : In Vitro Study
Additional Links
Substances : Caffeic Acid : CK(96) : AC(61), Caffeic acid phenethyl ester : CK(172) : AC(99)
Diseases : Breast Cancer: Triple Negative : CK(708) : AC(466)
Pharmacological Actions : Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304), Cell cycle arrest : CK(1678) : AC(1348)
Additional Keywords : Antiproliferative : CK(65) : AC(52), Apoptotic, Breast Cancer: Triple Negative, Caffeic Acid, Caffeic acid phenethyl ester, Cell cycle arrest

Cinnamon extract from Sanyangxuedai may be effective for treating leukemia.

Article Published Date : Aug 18, 2016
Study Type : In Vitro Study
Additional Links
Substances : Cinnamon : CK(406) : AC(150)
Diseases : Leukemia : CK(1709) : AC(739)
Pharmacological Actions : Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304), Cell cycle arrest : CK(1678) : AC(1348)
Additional Keywords : Antiproliferative : CK(65) : AC(52), Apoptotic, Cell cycle arrest, cinnamon, leukemia, Plant Extracts : CK(14140) : AC(5210)

Combined use of lower concentrations of jerantinine A and γ-tocotrienol induced potent cytotoxic effects on U87MG cancer cells.

Article Published Date : Jun 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Vitamin E: Gamma-tocotrienol : CK(51) : AC(33)
Diseases : Glioblastoma : CK(545) : AC(272)
Pharmacological Actions : Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304), Cell cycle arrest : CK(1678) : AC(1348), Chemoprotective Agents : CK(2322) : AC(906), Chemosensitizer : CK(1124) : AC(854), Chemotherapeutic : CK(2328) : AC(1086), Tumor Suppressor Protein p53 Upregulation : CK(585) : AC(431)
Additional Keywords : Antiproliferative : CK(65) : AC(52), Apoptotic, Cell cycle arrest, Glioblastoma, Natural Substance/Drug Synergy : CK(957) : AC(485), Vitamin E: Gamma-tocotrienol

Diallyl trisulfide suppresses tumor growth and potentiates cisplatin efficacy in gastric cancer treatment.

Article Published Date : Mar 26, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Dimethyl trisulfide (DMTS) : CK(8) : AC(5)
Diseases : Gastric Cancer : CK(1165) : AC(504)
Pharmacological Actions : Apoptotic : CK(6986) : AC(5304), Cell cycle arrest : CK(1678) : AC(1348), Chemosensitizer : CK(1124) : AC(854)
Additional Keywords : Apoptotic, Cell cycle arrest, Chemosensitizer, Chemotherapeutic Synergy: Cisplatin : CK(290) : AC(232), Dimethyl trisulfide (DMTS), gastric cancer

Ethanol extract of Antrodia camphorata inhibits proliferation of HCT-8 human colorectal cancer cells.

Article Published Date : Sep 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Antrodia camphorata : CK(52) : AC(33)
Diseases : Colorectal Cancer : CK(3666) : AC(1651)
Pharmacological Actions : Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304), Cell cycle arrest : CK(1678) : AC(1348)
Additional Keywords : Antiproliferative : CK(65) : AC(52), Antrodia camphorata, Apoptotic, Cell cycle arrest, COLORECTAL CANCER

Harmaline induces cell cycle arrest and apoptosis in SGC-7901 cells.

Article Published Date : Dec 17, 2015
Study Type : Animal Study
Additional Links
Substances : Syrian rue : CK(1) : AC(1)
Diseases : Gastric Cancer : CK(1165) : AC(504)
Pharmacological Actions : Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304), Cell cycle arrest : CK(1678) : AC(1348)
Additional Keywords : Antiproliferative : CK(65) : AC(52), Apoptotic, Cell cycle arrest, gastric cancer, Syrian rue

Honokiol is a good candidate for further studies as a possible treatment for malignant melanoma.

Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Honokiol : CK(260) : AC(168)
Diseases : Malignant Melanoma : CK(87) : AC(38)
Pharmacological Actions : Apoptotic : CK(6986) : AC(5304), Cell cycle arrest : CK(1678) : AC(1348)
Additional Keywords : Apoptotic, Cell cycle arrest, Honokiol, Malignant Melanoma

Tangeretin may be a therapeutic agent for glioblastoma treatment.

Article Published Date : Jun 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Tangeretin : CK(38) : AC(24)
Diseases : Glioblastoma : CK(545) : AC(272)
Pharmacological Actions : Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304), Cell cycle arrest : CK(1678) : AC(1348)
Additional Keywords : Antiproliferative : CK(65) : AC(52), Apoptotic, Cell cycle arrest, Glioblastoma, Tangeretin

Tea polyphenols induce S phase arrest and apoptosis in gallbladder cancer cells.

Article Published Date : Feb 28, 2018
Study Type : Animal Study
Additional Links
Substances : Polyphenols : CK(1878) : AC(700)
Diseases : Gallbladder Cancer : CK(96) : AC(29)
Pharmacological Actions : Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304), Cell cycle arrest : CK(1678) : AC(1348)
Additional Keywords : Antiproliferative : CK(65) : AC(52), Apoptotic, Cell cycle arrest, Gallbladder Cancer, POLYPHENOLS : CK(1) : AC(1)

Vitamin C with decitabine activates TET2 in leukemic cells and significantly improves overall survival in elderly patients with acute myeloid leukemia.

Article Published Date : Jan 01, 2018
Study Type : In Vitro Study
Additional Links
Substances : Vitamin C : CK(4687) : AC(1149), Vitamin C: Intravenous : CK(290) : AC(48)
Diseases : Acute Myeloid Leukemia : CK(242) : AC(115)
Pharmacological Actions : Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304), Cell cycle arrest : CK(1678) : AC(1348), Chemotherapeutic : CK(2328) : AC(1086)
Additional Keywords : Acute Myeloid Leukemia, Antiproliferative : CK(65) : AC(52), Apoptotic, Cell cycle arrest, Chemotherapeutic, Natural Substance/Drug Synergy : CK(957) : AC(485), Vitamin C : CK(1) : AC(1), Vitamin C: Intravenous

Wasabi compounds may possess activity against the growth and cancer stem cells phenotypes of human pancreatic cancer cells.

Article Published Date : Dec 31, 2013
Study Type : In Vitro Study
Additional Links
Substances : Isothiocyanates : CK(1203) : AC(596), Wasabi : CK(24) : AC(19)
Diseases : Pancreatic Cancer : CK(1307) : AC(451)
Pharmacological Actions : Apoptotic : CK(6986) : AC(5304), Cell cycle arrest : CK(1678) : AC(1348)
Additional Keywords : Apoptotic, Cancer Stem Cells : CK(375) : AC(276), Cell cycle arrest, Pancreatic Cancer : CK(1) : AC(1)

Withaferin A directly inhibits the proliferation and metastatic activity of gastric cancer cells.

Article Published Date : Jun 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Ashwagandha : CK(418) : AC(173)
Diseases : Gastric Cancer : CK(1165) : AC(504)
Pharmacological Actions : Anti-metastatic : CK(1972) : AC(1481), Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304), Cell cycle arrest : CK(1678) : AC(1348)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(65) : AC(52), Apoptotic, Ashwagandha, Cell cycle arrest, gastric cancer

Xanthones from Garcinia mangostana fruit hulls were cytotoxic against cancer cell lines.

Article Published Date : Jan 16, 2017
Study Type : In Vitro Study
Additional Links
Substances : Mangosteen : CK(152) : AC(77), Xanthones : CK(32) : AC(24)
Diseases : Breast Cancer : CK(6327) : AC(2272), Colorectal Cancer : CK(3666) : AC(1651), Liver Cancer : CK(2460) : AC(1189)
Pharmacological Actions : Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304), Cell cycle arrest : CK(1678) : AC(1348)
Additional Keywords : Antiproliferative : CK(65) : AC(52), Apoptotic, Breast Cancer : CK(113) : AC(34), Cell cycle arrest, COLORECTAL CANCER, liver cancer, Mangosteen, Xanthones : CK(64) : AC(40)

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