Results for Cell cycle arrest

A review of the multiple targets and signalling pathways of ginsenosides in cancers.

Article Published Date : Dec 31, 2015
Study Type : Review
Additional Links
Substances : Ginsenosides : CK(2639) : AC(1451)
Diseases : Cancers: All : CK(34182) : AC(13958)
Pharmacological Actions : Anti-Inflammatory Agents : CK(35225) : AC(14988), Anti-metastatic : CK(2811) : AC(2130), Antiproliferative : CK(9389) : AC(7276), Cell cycle arrest : CK(2100) : AC(1696)
Additional Keywords : Anti-Inflammatory Agents, Anti-metastatic, Antiproliferative : CK(75) : AC(61), Cancers: All, Cell cycle arrest, Ginsenosides

An extract of Litchi seed has potential for development into a safe and potent alternative therapy for prostate cancer patients.

Article Published Date : Jan 29, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Litchi : CK(35) : AC(23)
Diseases : Prostate Cancer : CK(2763) : AC(1027)
Pharmacological Actions : Anti-metastatic : CK(2811) : AC(2130), Apoptotic : CK(9052) : AC(7195), Cell cycle arrest : CK(2100) : AC(1696), P21 Activation : CK(197) : AC(142)
Additional Keywords : Anti-metastatic, Apoptotic, Cell cycle arrest, Litchi, P21 Activation, Plant Extracts : CK(18030) : AC(6692), prostate cancer

Baicalein induces cancer cell apoptosis and cause cell cycle arrest.

Article Published Date : Jul 31, 2016
Study Type : Review
Additional Links
Substances : Baicalein : CK(276) : AC(177)
Diseases : Cancers: All : CK(34182) : AC(13958)
Pharmacological Actions : Antiproliferative : CK(9389) : AC(7276), Apoptotic : CK(9052) : AC(7195), Cell cycle arrest : CK(2100) : AC(1696)
Additional Keywords : Antiproliferative : CK(75) : AC(61), Apoptotic, Baicalein, Cancer : CK(50) : AC(12), Cell cycle arrest

Caffeic acid and caffeic acid phenethyl ester induce apoptosis and cell cycle arrest of breast cancer cells MDA-MB-231.

Article Published Date : Sep 14, 2017
Study Type : In Vitro Study
Additional Links
Substances : Caffeic Acid : CK(135) : AC(86), Caffeic acid phenethyl ester : CK(284) : AC(172)
Diseases : Breast Cancer: Triple Negative : CK(943) : AC(639)
Pharmacological Actions : Antiproliferative : CK(9389) : AC(7276), Apoptotic : CK(9052) : AC(7195), Cell cycle arrest : CK(2100) : AC(1696)
Additional Keywords : Antiproliferative : CK(75) : AC(61), Apoptotic, Breast Cancer: Triple Negative, Caffeic Acid, Caffeic acid phenethyl ester, Cell cycle arrest

Cinnamon extract from Sanyangxuedai may be effective for treating leukemia.

Article Published Date : Aug 18, 2016
Study Type : In Vitro Study
Additional Links
Substances : Cinnamon : CK(691) : AC(201)
Diseases : Leukemia : CK(1974) : AC(887)
Pharmacological Actions : Antiproliferative : CK(9389) : AC(7276), Apoptotic : CK(9052) : AC(7195), Cell cycle arrest : CK(2100) : AC(1696)
Additional Keywords : Antiproliferative : CK(75) : AC(61), Apoptotic, Cell cycle arrest, cinnamon, leukemia, Plant Extracts : CK(18030) : AC(6692)

Combined use of lower concentrations of jerantinine A and γ-tocotrienol induced potent cytotoxic effects on U87MG cancer cells.

Article Published Date : Jun 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Vitamin E: Gamma-tocotrienol : CK(51) : AC(33)
Diseases : Glioblastoma : CK(673) : AC(384)
Pharmacological Actions : Antiproliferative : CK(9389) : AC(7276), Apoptotic : CK(9052) : AC(7195), Cell cycle arrest : CK(2100) : AC(1696), Chemoprotective Agents : CK(3736) : AC(1543), Chemosensitizer : CK(1616) : AC(1247), Chemotherapeutic : CK(3533) : AC(1480), Tumor Suppressor Protein p53 Upregulation : CK(742) : AC(544)
Additional Keywords : Antiproliferative : CK(75) : AC(61), Apoptotic, Cell cycle arrest, Glioblastoma, Natural Substance/Drug Synergy : CK(1463) : AC(697), Vitamin E: Gamma-tocotrienol

Diallyl trisulfide suppresses tumor growth and potentiates cisplatin efficacy in gastric cancer treatment.

Article Published Date : Mar 26, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Dimethyl trisulfide (DMTS) : CK(14) : AC(8)
Diseases : Gastric Cancer : CK(1576) : AC(713)
Pharmacological Actions : Apoptotic : CK(9052) : AC(7195), Cell cycle arrest : CK(2100) : AC(1696), Chemosensitizer : CK(1616) : AC(1247)
Additional Keywords : Apoptotic, Cell cycle arrest, Chemosensitizer, Chemotherapeutic Synergy: Cisplatin : CK(420) : AC(332), Dimethyl trisulfide (DMTS), gastric cancer

Ethanol extract of Antrodia camphorata inhibits proliferation of HCT-8 human colorectal cancer cells.

Article Published Date : Sep 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Antrodia camphorata : CK(52) : AC(33)
Diseases : Colorectal Cancer : CK(4802) : AC(2225)
Pharmacological Actions : Antiproliferative : CK(9389) : AC(7276), Apoptotic : CK(9052) : AC(7195), Cell cycle arrest : CK(2100) : AC(1696)
Additional Keywords : Antiproliferative : CK(75) : AC(61), Antrodia camphorata, Apoptotic, Cell cycle arrest, COLORECTAL CANCER

Harmaline induces cell cycle arrest and apoptosis in SGC-7901 cells.

Article Published Date : Dec 17, 2015
Study Type : Animal Study
Additional Links
Substances : Syrian rue : CK(76) : AC(46)
Diseases : Gastric Cancer : CK(1576) : AC(713)
Pharmacological Actions : Antiproliferative : CK(9389) : AC(7276), Apoptotic : CK(9052) : AC(7195), Cell cycle arrest : CK(2100) : AC(1696)
Additional Keywords : Antiproliferative : CK(75) : AC(61), Apoptotic, Cell cycle arrest, gastric cancer, Syrian rue

Honokiol is a good candidate for further studies as a possible treatment for malignant melanoma.

Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Honokiol : CK(429) : AC(267)
Diseases : Malignant Melanoma : CK(96) : AC(47)
Pharmacological Actions : Apoptotic : CK(9052) : AC(7195), Cell cycle arrest : CK(2100) : AC(1696)
Additional Keywords : Apoptotic, Cell cycle arrest, Honokiol, Malignant Melanoma

Tangeretin may be a therapeutic agent for glioblastoma treatment.

Article Published Date : Jun 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Tangeretin : CK(163) : AC(93)
Diseases : Glioblastoma : CK(673) : AC(384)
Pharmacological Actions : Antiproliferative : CK(9389) : AC(7276), Apoptotic : CK(9052) : AC(7195), Cell cycle arrest : CK(2100) : AC(1696)
Additional Keywords : Antiproliferative : CK(75) : AC(61), Apoptotic, Cell cycle arrest, Glioblastoma, Tangeretin

Tea polyphenols induce S phase arrest and apoptosis in gallbladder cancer cells.

Article Published Date : Feb 28, 2018
Study Type : Animal Study
Additional Links
Substances : Polyphenols : CK(2723) : AC(992)
Diseases : Gallbladder Cancer : CK(103) : AC(34)
Pharmacological Actions : Antiproliferative : CK(9389) : AC(7276), Apoptotic : CK(9052) : AC(7195), Cell cycle arrest : CK(2100) : AC(1696)
Additional Keywords : Antiproliferative : CK(75) : AC(61), Apoptotic, Cell cycle arrest, Gallbladder Cancer, POLYPHENOLS : CK(16) : AC(5)

Vitamin C with decitabine activates TET2 in leukemic cells and significantly improves overall survival in elderly patients with acute myeloid leukemia.

Article Published Date : Jan 01, 2018
Study Type : In Vitro Study
Additional Links
Substances : Vitamin C : CK(6013) : AC(1395), Vitamin C: Intravenous : CK(404) : AC(60)
Diseases : Acute Myeloid Leukemia : CK(289) : AC(150)
Pharmacological Actions : Antiproliferative : CK(9389) : AC(7276), Apoptotic : CK(9052) : AC(7195), Cell cycle arrest : CK(2100) : AC(1696), Chemotherapeutic : CK(3533) : AC(1480)
Additional Keywords : Acute Myeloid Leukemia, Antiproliferative : CK(75) : AC(61), Apoptotic, Cell cycle arrest, Chemotherapeutic, Natural Substance/Drug Synergy : CK(1463) : AC(697), Vitamin C : CK(48) : AC(13), Vitamin C: Intravenous

Wasabi compounds may possess activity against the growth and cancer stem cells phenotypes of human pancreatic cancer cells.

Article Published Date : Dec 31, 2013
Study Type : In Vitro Study
Additional Links
Substances : Isothiocyanates : CK(1659) : AC(804), Wasabi : CK(47) : AC(23)
Diseases : Pancreatic Cancer : CK(1504) : AC(557)
Pharmacological Actions : Apoptotic : CK(9052) : AC(7195), Cell cycle arrest : CK(2100) : AC(1696)
Additional Keywords : Apoptotic, Cancer Stem Cells : CK(492) : AC(362), Cell cycle arrest, Pancreatic Cancer : CK(2) : AC(2)

Withaferin A directly inhibits the proliferation and metastatic activity of gastric cancer cells.

Article Published Date : Jun 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Ashwagandha : CK(694) : AC(300)
Diseases : Gastric Cancer : CK(1576) : AC(713)
Pharmacological Actions : Anti-metastatic : CK(2811) : AC(2130), Antiproliferative : CK(9389) : AC(7276), Apoptotic : CK(9052) : AC(7195), Cell cycle arrest : CK(2100) : AC(1696)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(75) : AC(61), Apoptotic, Ashwagandha, Cell cycle arrest, gastric cancer

Xanthones from Garcinia mangostana fruit hulls were cytotoxic against cancer cell lines.

Article Published Date : Jan 16, 2017
Study Type : In Vitro Study
Additional Links
Substances : Mangosteen : CK(249) : AC(130), Xanthones : CK(52) : AC(44)
Diseases : Breast Cancer : CK(7730) : AC(2951), Colorectal Cancer : CK(4802) : AC(2225), Liver Cancer : CK(3026) : AC(1608)
Pharmacological Actions : Antiproliferative : CK(9389) : AC(7276), Apoptotic : CK(9052) : AC(7195), Cell cycle arrest : CK(2100) : AC(1696)
Additional Keywords : Antiproliferative : CK(75) : AC(61), Apoptotic, Breast Cancer : CK(113) : AC(34), Cell cycle arrest, COLORECTAL CANCER, liver cancer, Mangosteen, Xanthones : CK(82) : AC(54)

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