Results for Cell cycle arrest

A review of the multiple targets and signalling pathways of ginsenosides in cancers.

Article Published Date : Dec 31, 2015
Study Type : Review
Additional Links
Substances : Ginsenosides : CK(2640) : AC(1452)
Diseases : Cancers: All : CK(36376) : AC(14347)
Pharmacological Actions : Anti-Inflammatory Agents : CK(39701) : AC(15834), Anti-metastatic : CK(2868) : AC(2180), Antiproliferative : CK(9993) : AC(7483), Cell cycle arrest : CK(2120) : AC(1715)
Additional Keywords : Anti-Inflammatory Agents, Anti-metastatic, Antiproliferative : CK(75) : AC(61), Cancers: All, Cell cycle arrest, Ginsenosides

An extract of Litchi seed has potential for development into a safe and potent alternative therapy for prostate cancer patients.

Article Published Date : Jan 29, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Litchi : CK(35) : AC(23)
Diseases : Prostate Cancer : CK(2794) : AC(1044)
Pharmacological Actions : Anti-metastatic : CK(2868) : AC(2180), Apoptotic : CK(9578) : AC(7374), Cell cycle arrest : CK(2120) : AC(1715), P21 Activation : CK(206) : AC(144)
Additional Keywords : Anti-metastatic, Apoptotic, Cell cycle arrest, Litchi, P21 Activation, Plant Extracts : CK(18759) : AC(6780), prostate cancer

Baicalein induces cancer cell apoptosis and cause cell cycle arrest.

Article Published Date : Jul 31, 2016
Study Type : Review
Additional Links
Substances : Baicalein : CK(312) : AC(202)
Diseases : Cancers: All : CK(36376) : AC(14347)
Pharmacological Actions : Antiproliferative : CK(9993) : AC(7483), Apoptotic : CK(9578) : AC(7374), Cell cycle arrest : CK(2120) : AC(1715)
Additional Keywords : Antiproliferative : CK(75) : AC(61), Apoptotic, Baicalein, Cancer : CK(50) : AC(12), Cell cycle arrest

Caffeic acid and caffeic acid phenethyl ester induce apoptosis and cell cycle arrest of breast cancer cells MDA-MB-231.

Article Published Date : Sep 14, 2017
Study Type : In Vitro Study
Additional Links
Substances : Caffeic Acid : CK(136) : AC(87), Caffeic acid phenethyl ester : CK(284) : AC(172)
Diseases : Breast Cancer: Triple Negative : CK(970) : AC(659)
Pharmacological Actions : Antiproliferative : CK(9993) : AC(7483), Apoptotic : CK(9578) : AC(7374), Cell cycle arrest : CK(2120) : AC(1715)
Additional Keywords : Antiproliferative : CK(75) : AC(61), Apoptotic, Breast Cancer: Triple Negative, Caffeic Acid, Caffeic acid phenethyl ester, Cell cycle arrest

Cinnamon extract from Sanyangxuedai may be effective for treating leukemia.

Article Published Date : Aug 18, 2016
Study Type : In Vitro Study
Additional Links
Substances : Cinnamon : CK(692) : AC(202)
Diseases : Leukemia : CK(2094) : AC(910)
Pharmacological Actions : Antiproliferative : CK(9993) : AC(7483), Apoptotic : CK(9578) : AC(7374), Cell cycle arrest : CK(2120) : AC(1715)
Additional Keywords : Antiproliferative : CK(75) : AC(61), Apoptotic, Cell cycle arrest, cinnamon, leukemia, Plant Extracts : CK(18759) : AC(6780)

Combined use of lower concentrations of jerantinine A and γ-tocotrienol induced potent cytotoxic effects on U87MG cancer cells.

Article Published Date : Jun 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Vitamin E: Gamma-tocotrienol : CK(51) : AC(33)
Diseases : Glioblastoma : CK(729) : AC(403)
Pharmacological Actions : Antiproliferative : CK(9993) : AC(7483), Apoptotic : CK(9578) : AC(7374), Cell cycle arrest : CK(2120) : AC(1715), Chemoprotective Agents : CK(4277) : AC(1620), Chemosensitizer : CK(1656) : AC(1269), Chemotherapeutic : CK(4386) : AC(1631), Tumor Suppressor Protein p53 Upregulation : CK(753) : AC(552)
Additional Keywords : Antiproliferative : CK(75) : AC(61), Apoptotic, Cell cycle arrest, Glioblastoma, Natural Substance/Drug Synergy : CK(1526) : AC(720), Vitamin E: Gamma-tocotrienol

Diallyl trisulfide suppresses tumor growth and potentiates cisplatin efficacy in gastric cancer treatment.

Article Published Date : Mar 26, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Dimethyl trisulfide (DMTS) : CK(14) : AC(8)
Diseases : Gastric Cancer : CK(1619) : AC(725)
Pharmacological Actions : Apoptotic : CK(9578) : AC(7374), Cell cycle arrest : CK(2120) : AC(1715), Chemosensitizer : CK(1656) : AC(1269)
Additional Keywords : Apoptotic, Cell cycle arrest, Chemosensitizer, Chemotherapeutic Synergy: Cisplatin : CK(430) : AC(339), Dimethyl trisulfide (DMTS), gastric cancer

Ethanol extract of Antrodia camphorata inhibits proliferation of HCT-8 human colorectal cancer cells.

Article Published Date : Sep 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Antrodia camphorata : CK(52) : AC(33)
Diseases : Colorectal Cancer : CK(4889) : AC(2276)
Pharmacological Actions : Antiproliferative : CK(9993) : AC(7483), Apoptotic : CK(9578) : AC(7374), Cell cycle arrest : CK(2120) : AC(1715)
Additional Keywords : Antiproliferative : CK(75) : AC(61), Antrodia camphorata, Apoptotic, Cell cycle arrest, COLORECTAL CANCER

Harmaline induces cell cycle arrest and apoptosis in SGC-7901 cells.

Article Published Date : Dec 17, 2015
Study Type : Animal Study
Additional Links
Substances : Syrian rue : CK(84) : AC(51)
Diseases : Gastric Cancer : CK(1619) : AC(725)
Pharmacological Actions : Antiproliferative : CK(9993) : AC(7483), Apoptotic : CK(9578) : AC(7374), Cell cycle arrest : CK(2120) : AC(1715)
Additional Keywords : Antiproliferative : CK(75) : AC(61), Apoptotic, Cell cycle arrest, gastric cancer, Syrian rue

Honokiol is a good candidate for further studies as a possible treatment for malignant melanoma.

Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Honokiol : CK(435) : AC(271)
Diseases : Malignant Melanoma : CK(97) : AC(48)
Pharmacological Actions : Apoptotic : CK(9578) : AC(7374), Cell cycle arrest : CK(2120) : AC(1715)
Additional Keywords : Apoptotic, Cell cycle arrest, Honokiol, Malignant Melanoma

Tangeretin may be a therapeutic agent for glioblastoma treatment.

Article Published Date : Jun 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Tangeretin : CK(163) : AC(93)
Diseases : Glioblastoma : CK(729) : AC(403)
Pharmacological Actions : Antiproliferative : CK(9993) : AC(7483), Apoptotic : CK(9578) : AC(7374), Cell cycle arrest : CK(2120) : AC(1715)
Additional Keywords : Antiproliferative : CK(75) : AC(61), Apoptotic, Cell cycle arrest, Glioblastoma, Tangeretin

Tea polyphenols induce S phase arrest and apoptosis in gallbladder cancer cells.

Article Published Date : Feb 28, 2018
Study Type : Animal Study
Additional Links
Substances : Polyphenols : CK(2736) : AC(1003)
Diseases : Gallbladder Cancer : CK(115) : AC(37)
Pharmacological Actions : Antiproliferative : CK(9993) : AC(7483), Apoptotic : CK(9578) : AC(7374), Cell cycle arrest : CK(2120) : AC(1715)
Additional Keywords : Antiproliferative : CK(75) : AC(61), Apoptotic, Cell cycle arrest, Gallbladder Cancer, POLYPHENOLS : CK(16) : AC(5)

Vitamin C with decitabine activates TET2 in leukemic cells and significantly improves overall survival in elderly patients with acute myeloid leukemia.

Article Published Date : Jan 01, 2018
Study Type : In Vitro Study
Additional Links
Substances : Vitamin C : CK(6065) : AC(1407), Vitamin C: Intravenous : CK(404) : AC(60)
Diseases : Acute Myeloid Leukemia : CK(300) : AC(152)
Pharmacological Actions : Antiproliferative : CK(9993) : AC(7483), Apoptotic : CK(9578) : AC(7374), Cell cycle arrest : CK(2120) : AC(1715), Chemotherapeutic : CK(4386) : AC(1631)
Additional Keywords : Acute Myeloid Leukemia, Antiproliferative : CK(75) : AC(61), Apoptotic, Cell cycle arrest, Chemotherapeutic, Natural Substance/Drug Synergy : CK(1526) : AC(720), Vitamin C : CK(48) : AC(13), Vitamin C: Intravenous

Wasabi compounds may possess activity against the growth and cancer stem cells phenotypes of human pancreatic cancer cells.

Article Published Date : Dec 31, 2013
Study Type : In Vitro Study
Additional Links
Substances : Isothiocyanates : CK(1659) : AC(819), Wasabi : CK(47) : AC(23)
Diseases : Pancreatic Cancer : CK(1547) : AC(564)
Pharmacological Actions : Apoptotic : CK(9578) : AC(7374), Cell cycle arrest : CK(2120) : AC(1715)
Additional Keywords : Apoptotic, Cancer Stem Cells : CK(501) : AC(365), Cell cycle arrest, Pancreatic Cancer : CK(2) : AC(2)

Withaferin A directly inhibits the proliferation and metastatic activity of gastric cancer cells.

Article Published Date : Jun 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Ashwagandha : CK(748) : AC(301)
Diseases : Gastric Cancer : CK(1619) : AC(725)
Pharmacological Actions : Anti-metastatic : CK(2868) : AC(2180), Antiproliferative : CK(9993) : AC(7483), Apoptotic : CK(9578) : AC(7374), Cell cycle arrest : CK(2120) : AC(1715)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(75) : AC(61), Apoptotic, Ashwagandha, Cell cycle arrest, gastric cancer

Xanthones from Garcinia mangostana fruit hulls were cytotoxic against cancer cell lines.

Article Published Date : Jan 16, 2017
Study Type : In Vitro Study
Additional Links
Substances : Mangosteen : CK(261) : AC(133), Xanthones : CK(84) : AC(66)
Diseases : Breast Cancer : CK(8291) : AC(3037), Colorectal Cancer : CK(4889) : AC(2276), Liver Cancer : CK(3115) : AC(1639)
Pharmacological Actions : Antiproliferative : CK(9993) : AC(7483), Apoptotic : CK(9578) : AC(7374), Cell cycle arrest : CK(2120) : AC(1715)
Additional Keywords : Antiproliferative : CK(75) : AC(61), Apoptotic, Breast Cancer : CK(113) : AC(34), Cell cycle arrest, COLORECTAL CANCER, liver cancer, Mangosteen, Xanthones : CK(86) : AC(57)

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