Results for Chemopreventive

A diet rich in healthy plant foods and especially total or raw vegetable may protect against prostate cancer.

Article Published Date : Jan 26, 2017
Study Type : Human Study
Additional Links
Diseases : Prostate Cancer : CK(2805) : AC(1046)
Pharmacological Actions : Chemopreventive : CK(6580) : AC(2166)
Additional Keywords : Chemopreventive, prostate cancer

A treatment approach including intravenous α-lipoic acid and low-dose naltrexone led to stable disease in this patient.

Article Published Date : Nov 30, 2017
Study Type : Human: Case Report
Additional Links
Substances : Alpha-Lipoic Acid : CK(1501) : AC(366), Vitamin C: Intravenous : CK(404) : AC(60)
Diseases : Kidney Cancer : CK(388) : AC(181)
Pharmacological Actions : Chemopreventive : CK(6580) : AC(2166), Chemotherapeutic : CK(4390) : AC(1635)
Additional Keywords : Alpha-Lipoic Acid, Chemopreventive, Chemotherapeutic, Kidney Cancer, Vitamin C: Intravenous

Adherence to the Mediterranean diet was associated with a reduced breast cancer risk.

Article Published Date : Mar 07, 2018
Study Type : Human Study
Additional Links
Diseases : Breast Cancer : CK(8297) : AC(3043)
Therapeutic Actions : Mediterranean diet
Pharmacological Actions : Chemopreventive : CK(6580) : AC(2166)
Additional Keywords : Breast Cancer : CK(113) : AC(34), Chemopreventive, Mediterranean diet, Risk Reduction : CK(17935) : AC(2006)

Adlay bran ethanolic extract suppressed 1,2-dimethylhydrazine-indued preneoplastic lesions of the colon.

Article Published Date : Jul 13, 2010
Study Type : Animal Study
Additional Links
Substances : Adlay : CK(128) : AC(79)
Diseases : Colon Cancer : CK(1920) : AC(1203)
Pharmacological Actions : Anti-Inflammatory Agents : CK(39739) : AC(15859), Chemopreventive : CK(6580) : AC(2166), Cyclooxygenase 2 Inhibitors : CK(2264) : AC(1327)
Additional Keywords : Adlay, Anti-Inflammatory Agents, Chemopreventive, COLON CANCER, Cyclooxygenase 2 Inhibitors, Plant Extracts : CK(18764) : AC(6783)

Adlay is a potential chemopreventive TCM to block multistage carcinogenesis with anti-initiation, promotion and progression properties.

Article Published Date : Sep 30, 2012
Study Type : Review
Additional Links
Substances : Adlay : CK(128) : AC(79)
Diseases : Cancers: All : CK(36404) : AC(14363)
Pharmacological Actions : Antioxidants : CK(34553) : AC(14500), Antiproliferative : CK(10001) : AC(7491), Chemopreventive : CK(6580) : AC(2166), Nrf2 activation : CK(3156) : AC(1794)
Additional Keywords : Adlay, Antioxidants : CK(303) : AC(126), Antiproliferative : CK(75) : AC(61), Cancers: All, Chemopreventive, Nrf2 activation

Antimutagenic constituents of adlay with potential cancer chemopreventive activity.

Article Published Date : Jun 21, 2011
Study Type : In Vitro Study
Additional Links
Substances : Adlay : CK(128) : AC(79)
Diseases : Cancers: All : CK(36404) : AC(14363)
Pharmacological Actions : Antimutagenic Agents : CK(218) : AC(138), Chemopreventive : CK(6580) : AC(2166)
Additional Keywords : Adlay, Antimutagenic Agents, Cancers: All, Chemopreventive

Baicalein is a potential treatment for reducing the risk of estrogen-dependent breast cancer.

Article Published Date : Jan 01, 2017
Study Type : In Vitro Study
Additional Links
Diseases : Breast Cancer : CK(8297) : AC(3043)
Pharmacological Actions : Anticarcinogenic Agents : CK(2152) : AC(1018), Chemopreventive : CK(6580) : AC(2166)
Additional Keywords : 17beta-estradiol, Anticarcinogenic Agents, Breast Cancer : CK(113) : AC(34), Chemopreventive
Problem Substances : 17beta-estradiol : CK(51) : AC(14)

Compounds isolated from lichens are possible candidates for the management of oxidative stress, and in the treatment of chronic diseases.

Article Published Date : Sep 11, 2014
Study Type : Review
Additional Links
Substances : Lichens : CK(78) : AC(55)
Diseases : Cancers: All : CK(36404) : AC(14363), Chronic Disease : CK(216) : AC(57), Oxidative Stress : CK(14760) : AC(5717)
Pharmacological Actions : Antioxidants : CK(34553) : AC(14500), Chemopreventive : CK(6580) : AC(2166)
Additional Keywords : Antioxidants : CK(303) : AC(126), Cancers: All, Chemopreventive, chronic disease, Lichens, oxidative stress

Delta-tocotrienol inhibits pancreatic cancer stem-like cells and prevents pancreatic cancer metastasis.

Article Published Date : May 08, 2017
Study Type : In Vitro Study
Additional Links
Substances : Tocotrienol: Delta : CK(74) : AC(33), Vitamin E : CK(3040) : AC(571)
Diseases : Pancreatic Cancer : CK(1547) : AC(564)
Pharmacological Actions : Anti-metastatic : CK(2870) : AC(2182), Antiproliferative : CK(10001) : AC(7491), Chemopreventive : CK(6580) : AC(2166)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(75) : AC(61), Cancer Stem Cells : CK(501) : AC(365), Chemopreventive, Pancreatic Cancer : CK(2) : AC(2), Tocotrienol: Delta, VITAMIN E

Fasting selectively blocks development of acute lymphoblastic leukemia.

Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Diseases : Acute lymphoblastic leukemia (ALL) : CK(258) : AC(96), Acute T cell Leukemias : CK(48) : AC(45)
Therapeutic Actions : Fasting/Caloric Restriction : CK(820) : AC(176)
Pharmacological Actions : Antiproliferative : CK(10001) : AC(7491), Chemopreventive : CK(6580) : AC(2166)
Additional Keywords : Acute lymphoblastic leukemia (ALL), Acute T cell Leukemias, Antiproliferative : CK(75) : AC(61), Chemopreventive, Fasting/Caloric Restriction, Gene Exprsession Regulation, Selective Antiproliferation : CK(47) : AC(40)

Gallic acid remarkably ameliorated the destabilization of liver tissue architecture caused by N-nitrosodiethylamine.

Article Published Date : May 31, 2017
Study Type : Animal Study
Additional Links
Substances : Gallic Acid : CK(341) : AC(212)
Diseases : Liver Cancer : CK(3119) : AC(1641)
Pharmacological Actions : Anti-Inflammatory Agents : CK(39739) : AC(15859), Anticarcinogenic Agents : CK(2152) : AC(1018), Antioxidants : CK(34553) : AC(14500), Apoptotic : CK(9585) : AC(7379), Chemopreventive : CK(6580) : AC(2166)
Additional Keywords : Anti-Inflammatory Agents, Anticarcinogenic Agents, Antioxidants : CK(303) : AC(126), Apoptotic, Chemopreventive, Gallic Acid, liver cancer
Problem Substances : N-nitrosodiethylamine : CK(10) : AC(5)

Ganoderma lucidum triterpenes induce apoptosis in MCF-7 cells and attenuate DMBA induced mammary and skin carcinomas.

Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Reishi Mushroom : CK(650) : AC(349)
Diseases : Breast Cancer : CK(8297) : AC(3043), Skin Cancer : CK(1759) : AC(833)
Pharmacological Actions : Anticarcinogenic Agents : CK(2152) : AC(1018), Apoptotic : CK(9585) : AC(7379), Bcl-2 protein down-regulation : CK(711) : AC(529), Bcl-xL down-regulation : CK(41) : AC(30), Chemopreventive : CK(6580) : AC(2166), Cyclin D1 Down-Regulation : CK(143) : AC(106)
Additional Keywords : Anticarcinogenic Agents, Apoptotic, Bcl-2 protein down-regulation, Bcl-xL down-regulation, Breast Cancer : CK(113) : AC(34), Chemopreventive, Cyclin D1 Down-Regulation, Reishi Mushroom, skin cancer

Grain and sweet sorghum serves as a novel source of bioactive compounds for human health.

Article Published Date : Jun 28, 2017
Study Type : Review
Additional Links
Substances : Sorghum : CK(11) : AC(2)
Diseases : Colon Cancer : CK(1920) : AC(1203), Inflammation : CK(16108) : AC(5498)
Pharmacological Actions : Anti-Inflammatory Agents : CK(39739) : AC(15859), Antioxidants : CK(34553) : AC(14500), Chemopreventive : CK(6580) : AC(2166), Immunomodulatory : CK(6531) : AC(2360)
Additional Keywords : Anti-Inflammatory Agents, Antioxidants : CK(303) : AC(126), Chemopreventive, COLON CANCER, Immunomodulatory, Inflammation : CK(128) : AC(57), Sorghum

Higher consumption of nuts may be associated with a significantly reduced incidence of cancer recurrence and death in patients with stage III colon cancer.

Article Published Date : Feb 27, 2018
Study Type : Human Study
Additional Links
Substances : Nuts : CK(3250) : AC(485)
Diseases : Colon Cancer : CK(1920) : AC(1203)
Pharmacological Actions : Chemopreventive : CK(6580) : AC(2166)
Additional Keywords : Chemopreventive, COLON CANCER, nuts, Risk Reduction : CK(17935) : AC(2006)

Maternal folic acid supplementation before and during pregnancy seems to confer protection against the risk of childhood leukaemia in the offspring.

Article Published Date : Dec 31, 2016
Study Type : Review
Additional Links
Substances : Folic Acid : CK(1317) : AC(206)
Diseases : Folic Acid/Folate Deficiency : CK(266) : AC(40), Leukemia : CK(2094) : AC(910)
Pharmacological Actions : Chemopreventive : CK(6580) : AC(2166)
Additional Keywords : Chemopreventive, folic acid, Folic Acid/Folate Deficiency, leukemia, Risk Reduction : CK(17935) : AC(2006)

Mediterranean dietary pattern is associated to low risk of aggressive prostate cancer.

Article Published Date : Aug 21, 2017
Study Type : Human Study
Additional Links
Diseases : Prostate Cancer : CK(2805) : AC(1046)
Therapeutic Actions : Dietary Modification: Mediterranean Diet : CK(1804) : AC(216)
Pharmacological Actions : Chemopreventive : CK(6580) : AC(2166)
Additional Keywords : Chemopreventive, Dietary Modification: Mediterranean Diet, prostate cancer, Risk Reduction : CK(17935) : AC(2006)

Phloretin has a strong chemopreventive effect against aflatoxin B1.

Article Published Date : Dec 31, 2011
Study Type : In Vitro Study
Additional Links
Substances : Phloretin : CK(232) : AC(137)
Diseases : Liver Damage: Aflatoxin-Induced : CK(104) : AC(48)
Pharmacological Actions : Chemopreventive : CK(6580) : AC(2166), Nrf2 activation : CK(3156) : AC(1794)
Additional Keywords : Chemopreventive, Dose Response : CK(1770) : AC(700), Liver Damage: Aflatoxin-Induced, Nrf2 activation, Phloretin
Problem Substances : Aflatoxin : CK(230) : AC(87)

Pomegranate fruit extract significantly inhibits lung tumorigenesis in A/J mice.

Article Published Date : Mar 31, 2007
Study Type : Animal Study
Additional Links
Substances : Pomegranate : CK(1800) : AC(573)
Diseases : Benzo[a]pyrene-induced Toxicity : CK(215) : AC(129), Lung Cancer : CK(3063) : AC(1429)
Pharmacological Actions : Anticarcinogenic Agents : CK(2152) : AC(1018), Chemopreventive : CK(6580) : AC(2166), NF-kappaB Inhibitor : CK(5952) : AC(3464)
Additional Keywords : Anticarcinogenic Agents, Chemopreventive, lung cancer, NF-kappaB Inhibitor, Phytotherapy : CK(4003) : AC(1031), Plant Extracts : CK(18764) : AC(6783), pomegranate
Problem Substances : Benzo(a)pyrene : CK(184) : AC(108)

The antioxidant and immunomodulatory activities of royal jelly serve an important role on antitumor growth.

Article Published Date : Nov 30, 2017
Study Type : Animal Study
Additional Links
Substances : Royal Jelly : CK(636) : AC(235)
Diseases : Breast Cancer : CK(8297) : AC(3043)
Pharmacological Actions : Antioxidants : CK(34553) : AC(14500), Antiproliferative : CK(10001) : AC(7491), Chemopreventive : CK(6580) : AC(2166), Immunomodulatory : CK(6531) : AC(2360)
Additional Keywords : Antioxidants : CK(303) : AC(126), Antiproliferative : CK(75) : AC(61), Breast Cancer : CK(113) : AC(34), Chemopreventive, Immunomodulatory, Royal Jelly

The present results confirm a chemopreventive potential of pistachios.

Article Published Date : Dec 17, 2017
Study Type : In Vitro Study
Additional Links
Substances : pistachios
Diseases : Colon Cancer : CK(1920) : AC(1203)
Pharmacological Actions : Chemopreventive : CK(6580) : AC(2166)
Additional Keywords : Chemopreventive, COLON CANCER, pistachios

The present study shows that lichen compounds demonstrated strong antioxidant, antimicrobial, and anticancer properties.

Article Published Date : Oct 14, 2012
Study Type : Human In Vitro
Additional Links
Substances : Lichens : CK(78) : AC(55)
Diseases : Colon Cancer : CK(1920) : AC(1203), Melanoma : CK(924) : AC(552)
Pharmacological Actions : Antimicrobial : CK(1577) : AC(790), Antioxidants : CK(34553) : AC(14500), Chemopreventive : CK(6580) : AC(2166)
Additional Keywords : Antimicrobial, Antioxidants : CK(303) : AC(126), Chemopreventive, COLON CANCER, Lichens, melanoma

The results suggest that peptides from common bean cv. Azufrado Higuera could prevent colitis-associated colon carcinogenesis.

Article Published Date : Nov 30, 2017
Study Type : Animal Study
Additional Links
Substances : Common bean : CK(34) : AC(21)
Diseases : Colitis : CK(1542) : AC(735), Colon Cancer : CK(1920) : AC(1203)
Pharmacological Actions : Anticarcinogenic Agents : CK(2152) : AC(1018), Chemopreventive : CK(6580) : AC(2166)
Additional Keywords : Anticarcinogenic Agents, Chemopreventive, Colitis, COLON CANCER, Common bean

These findings suggest the possibility that adlay bran and its ethanolic extract and residue inhibit colonic preneoplastic lesions in an early stage.

Article Published Date : Jan 31, 2011
Study Type : Animal Study
Additional Links
Substances : Adlay : CK(128) : AC(79)
Diseases : Colon Cancer : CK(1920) : AC(1203)
Pharmacological Actions : Anticarcinogenic Agents : CK(2152) : AC(1018), Chemopreventive : CK(6580) : AC(2166)
Additional Keywords : Adlay, Anticarcinogenic Agents, Chemopreventive, COLON CANCER, Plant Extracts : CK(18764) : AC(6783)

This concludes Piper nigrum as a novel therapeutic spice for the treatment of colorectal carcinoma.

Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Black Pepper : CK(735) : AC(334)
Diseases : Colorectal Cancer : CK(4889) : AC(2276)
Pharmacological Actions : Antiproliferative : CK(10001) : AC(7491), Chemopreventive : CK(6580) : AC(2166)
Additional Keywords : Antiproliferative : CK(75) : AC(61), Black Pepper, Chemopreventive, COLORECTAL CANCER, Dose Response : CK(1770) : AC(700)

This study demonstrates the anti-metastatic and anti-EMT activities of Antrodia camphorate.

Article Published Date : Aug 16, 2017
Study Type : In Vitro Study
Additional Links
Substances : Antrodia camphorata : CK(52) : AC(33)
Diseases : Colon Cancer : CK(1920) : AC(1203)
Pharmacological Actions : Anti-metastatic : CK(2870) : AC(2182), Antineoplastic Agents : CK(2235) : AC(1468), Antiproliferative : CK(10001) : AC(7491), Chemopreventive : CK(6580) : AC(2166)
Additional Keywords : Anti-metastatic, Antineoplastic Agents : CK(78) : AC(35), Antiproliferative : CK(75) : AC(61), Antrodia camphorata, Chemopreventive, COLON CANCER

Vitamin C promotes apoptosis in breast cancer cells by increasing TRAIL expression.

Article Published Date : Mar 27, 2018
Study Type : In Vitro Study
Additional Links
Substances : Vitamin C : CK(6066) : AC(1408)
Diseases : Breast Cancer : CK(8297) : AC(3043), Breast Cancer: Triple Negative : CK(970) : AC(659)
Pharmacological Actions : Apoptotic : CK(9585) : AC(7379), Chemopreventive : CK(6580) : AC(2166)
Additional Keywords : Apoptotic, Breast Cancer : CK(113) : AC(34), Breast Cancer: Triple Negative, Chemopreventive, Vitamin C : CK(48) : AC(13)

Walnuts exhibit chemopreventive effects regarding the risk for colon cancer development by inducing expression of genes involved in detoxification.

Article Published Date : Oct 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Walnut : CK(803) : AC(198)
Diseases : Colon Cancer : CK(1920) : AC(1203)
Pharmacological Actions : Antiproliferative : CK(10001) : AC(7491), Apoptotic : CK(9585) : AC(7379), Chemopreventive : CK(6580) : AC(2166)
Additional Keywords : Antiproliferative : CK(75) : AC(61), Apoptotic, Chemopreventive, COLON CANCER, Gene Expression Regulation : CK(1401) : AC(623), Walnut

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