Results for Chemotherapeutic

A comprehensive review on anticancer mechanisms of crocin.

Article Published Date : Jul 02, 2017
Study Type : Review
Additional Links
Substances : Crocin : CK(745) : AC(319)
Diseases : Cancers: All : CK(38021) : AC(15295)
Pharmacological Actions : Anti-metastatic : CK(3105) : AC(2360), Antiproliferative : CK(11104) : AC(8317), Apoptotic : CK(10518) : AC(8130), Chemotherapeutic : CK(4561) : AC(1707), Telomerase Inhibitor : CK(104) : AC(71)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(75) : AC(61), Apoptotic, Cancers: All, Chemotherapeutic, Crocin, Telomerase Inhibitor

A treatment approach including intravenous α-lipoic acid and low-dose naltrexone led to stable disease in this patient.

Article Published Date : Nov 30, 2017
Study Type : Human: Case Report
Additional Links
Substances : Alpha-Lipoic Acid : CK(1551) : AC(379), Vitamin C: Intravenous : CK(404) : AC(60)
Diseases : Kidney Cancer : CK(405) : AC(193)
Pharmacological Actions : Chemopreventive : CK(6690) : AC(2222), Chemotherapeutic : CK(4561) : AC(1707)
Additional Keywords : Alpha-Lipoic Acid, Chemopreventive, Chemotherapeutic, Kidney Cancer, Vitamin C: Intravenous

Arctigenin results in autophagic cell death and decreased ER expression in ER-positive human breast cancer cells.

Article Published Date : Feb 08, 2018
Study Type : In Vitro Study
Additional Links
Substances : Arctigenin : CK(180) : AC(118)
Diseases : Breast Cancer : CK(8563) : AC(3201)
Pharmacological Actions : Chemotherapeutic : CK(4561) : AC(1707)
Additional Keywords : Arctigenin, Breast Cancer : CK(113) : AC(34), Chemotherapeutic, Natural Substance/Drug Synergy : CK(1675) : AC(775)

Genistein intake mimicking Asian consumption patterns improved response of mammary tumors to tamoxifen therapy.

Article Published Date : Jan 31, 2017
Study Type : Animal Study
Additional Links
Substances : Genistein : CK(951) : AC(439)
Diseases : Breast Cancer : CK(8563) : AC(3201)
Pharmacological Actions : Chemotherapeutic : CK(4561) : AC(1707), Immunomodulatory : CK(6995) : AC(2532)
Additional Keywords : Breast Cancer : CK(113) : AC(34), Chemotherapeutic, Gene Expression Regulation : CK(1435) : AC(630), Genistein, Immunomodulatory

Iscador Qu inhibits doxorubicin-induced senescence of MCF7 cells.

Article Published Date : Jun 18, 2017
Study Type : In Vitro Study
Additional Links
Substances : Mistletoe : CK(243) : AC(61)
Diseases : Breast Cancer : CK(8563) : AC(3201)
Pharmacological Actions : Chemotherapeutic : CK(4561) : AC(1707)
Additional Keywords : Breast Cancer : CK(113) : AC(34), Chemotherapeutic, Chemotherapeutic Synergy: Doxorubicin : CK(394) : AC(299), Mistletoe

Low-molecular-weight fucoidan combined with chemotarget agents significantly improved the disease control rate.

Article Published Date : Apr 20, 2017
Study Type : Human Study
Additional Links
Substances : Fucoidan : CK(888) : AC(453)
Diseases : Colorectal Cancer : CK(5144) : AC(2441)
Pharmacological Actions : Chemotherapeutic : CK(4561) : AC(1707)
Additional Keywords : Chemotherapeutic, COLORECTAL CANCER, Fucoidan

Melatonin could be used as an adjuvant agent with rapamycin in head and neck cancers.

Article Published Date : Dec 15, 2017
Study Type : In Vitro Study
Additional Links
Substances : Melatonin : CK(2959) : AC(926)
Diseases : Head and Neck Cancer : CK(825) : AC(197)
Pharmacological Actions : Chemoprotective Agents : CK(4587) : AC(1758), Chemotherapeutic : CK(4561) : AC(1707)
Additional Keywords : Chemoprotective Agents, Chemotherapeutic, Head and Neck Cancer, melatonin, Natural Substance/Drug Synergy : CK(1675) : AC(775)

Neferine augments the therapeutic efficacy of cisplatin in human lung adenocarcinoma cells.

Article Published Date : Apr 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Lotus : CK(454) : AC(291)
Diseases : Lung Cancer : CK(3253) : AC(1546)
Pharmacological Actions : Autophagy Up-regulation : CK(926) : AC(610), Chemotherapeutic : CK(4561) : AC(1707)
Additional Keywords : Autophagy Up-regulation, Chemotherapeutic, Chemotherapeutic Synergy: Cisplatin : CK(457) : AC(363), Lotus, lung cancer

Neferine revealed higher toxicity toward paclitaxel and doxorubicin-resistant breast, lung or colon cancer cells.

Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Lotus : CK(454) : AC(291)
Diseases : Breast Cancer : CK(8563) : AC(3201), Cancers: Multi-Drug Resistant : CK(202) : AC(162), Colon Cancer : CK(1977) : AC(1242), Lung Cancer : CK(3253) : AC(1546)
Pharmacological Actions : Chemosensitizer : CK(1772) : AC(1353), Chemotherapeutic : CK(4561) : AC(1707)
Additional Keywords : Breast Cancer : CK(113) : AC(34), Cancers: Multi-Drug Resistant, Chemosensitizer, Chemotherapeutic, COLON CANCER, Lotus, lung cancer

Phytochemistry, pharmacology, and therapeutic uses of black seed (Nigella sativa).

Article Published Date : Sep 30, 2016
Study Type : Review
Additional Links
Substances : Nigella sativa (aka Black Seed) : CK(2061) : AC(526)
Pharmacological Actions : Analgesics : CK(10210) : AC(1568), Anti-Inflammatory Agents : CK(43674) : AC(17512), Anticonvulsants : CK(1204) : AC(312), Antihypertensive Agents : CK(7484) : AC(1086), Antimicrobial : CK(1668) : AC(837), Antioxidants : CK(37417) : AC(15721), Chemotherapeutic : CK(4561) : AC(1707), Hypoglycemic Agents : CK(9853) : AC(2199), Hypolipidemic : CK(9799) : AC(2184)
Additional Keywords : Analgesics, Anti-Inflammatory Agents, Anticonvulsants, Antihypertensive Agents, Antimicrobial, Antioxidants : CK(303) : AC(126), Chemotherapeutic, Nigella sativa (aka Black Seed), Plant Extracts : CK(19783) : AC(7256)

Structural optimization of mangiferin binding to cancer molecular targets.

Article Published Date : Mar 19, 2018
Study Type : In Vitro Study
Additional Links
Substances : Mangiferin : CK(376) : AC(223)
Diseases : Cancers: All : CK(38021) : AC(15295)
Pharmacological Actions : Chemotherapeutic : CK(4561) : AC(1707)
Additional Keywords : Cancers: All, Chemotherapeutic, Mangiferin

These results suggest fisetin in combination with gemcitabine as a candidate for use in improved anticancer regimens.

Article Published Date : Jan 10, 2016
Study Type : In Vitro Study
Additional Links
Substances : Fisetin : CK(442) : AC(276), Flavonoids : CK(5535) : AC(2653)
Diseases : Cholangiocarcinoma : CK(223) : AC(97)
Pharmacological Actions : Antiproliferative : CK(11104) : AC(8317), Apoptotic : CK(10518) : AC(8130), Chemotherapeutic : CK(4561) : AC(1707)
Additional Keywords : Antiproliferative : CK(75) : AC(61), Apoptotic, Chemotherapeutic, Chemotherapeutic Synergy: Gemcitabine : CK(140) : AC(93), Cholangiocarcinoma, Fisetin, Flavonoids

This study confirms the potential of modified pectin to improve chemotherapeutic cancer treatments.

Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Modified Citrus Pectin : CK(120) : AC(33)
Diseases : Liver Cancer : CK(3345) : AC(1783), Lung Cancer : CK(3253) : AC(1546)
Pharmacological Actions : Apoptotic : CK(10518) : AC(8130), Chemotherapeutic : CK(4561) : AC(1707)
Additional Keywords : Apoptotic, Chemotherapeutic, liver cancer, lung cancer, Modified Citrus Pectin

This study provides evidence that blueberries may be unique sources for anti-AML therapy.

Article Published Date : Dec 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Blueberry : CK(1197) : AC(349)
Diseases : Acute Myeloid Leukemia : CK(308) : AC(157)
Pharmacological Actions : Chemotherapeutic : CK(4561) : AC(1707)
Additional Keywords : Acute Myeloid Leukemia, Blueberry, Chemotherapeutic

Vitamin C with decitabine activates TET2 in leukemic cells and significantly improves overall survival in elderly patients with acute myeloid leukemia.

Article Published Date : Jan 01, 2018
Study Type : In Vitro Study
Additional Links
Substances : Vitamin C : CK(6209) : AC(1438), Vitamin C: Intravenous : CK(404) : AC(60)
Diseases : Acute Myeloid Leukemia : CK(308) : AC(157)
Pharmacological Actions : Antiproliferative : CK(11104) : AC(8317), Apoptotic : CK(10518) : AC(8130), Cell cycle arrest : CK(2269) : AC(1841), Chemotherapeutic : CK(4561) : AC(1707)
Additional Keywords : Acute Myeloid Leukemia, Antiproliferative : CK(75) : AC(61), Apoptotic, Cell cycle arrest, Chemotherapeutic, Natural Substance/Drug Synergy : CK(1675) : AC(775), Vitamin C : CK(48) : AC(13), Vitamin C: Intravenous

Vitamin K has been shown to suppress the growth of liver cancer cells.

Article Published Date : Oct 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Vitamin K2 : CK(560) : AC(91)
Diseases : Liver Cancer : CK(3345) : AC(1783)
Pharmacological Actions : Antineoplastic Agents : CK(2510) : AC(1686), Apoptotic : CK(10518) : AC(8130), Chemotherapeutic : CK(4561) : AC(1707)
Additional Keywords : Antineoplastic Agents : CK(78) : AC(35), Apoptotic, Chemotherapeutic, liver cancer, Natural Substance/Drug Synergy : CK(1675) : AC(775), Vitamin K2 : CK(16) : AC(6)

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