Results for Chemotherapeutic

A comprehensive review on anticancer mechanisms of crocin.

Article Published Date : Jul 02, 2017
Study Type : Review
Additional Links
Substances : Crocin : CK(732) : AC(311)
Diseases : Cancers: All : CK(36404) : AC(14363)
Pharmacological Actions : Anti-metastatic : CK(2870) : AC(2182), Antiproliferative : CK(10001) : AC(7491), Apoptotic : CK(9585) : AC(7379), Chemotherapeutic : CK(4390) : AC(1635), Telomerase Inhibitor : CK(98) : AC(65)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(75) : AC(61), Apoptotic, Cancers: All, Chemotherapeutic, Crocin, Telomerase Inhibitor

A treatment approach including intravenous α-lipoic acid and low-dose naltrexone led to stable disease in this patient.

Article Published Date : Nov 30, 2017
Study Type : Human: Case Report
Additional Links
Substances : Alpha-Lipoic Acid : CK(1501) : AC(366), Vitamin C: Intravenous : CK(404) : AC(60)
Diseases : Kidney Cancer : CK(388) : AC(181)
Pharmacological Actions : Chemopreventive : CK(6580) : AC(2166), Chemotherapeutic : CK(4390) : AC(1635)
Additional Keywords : Alpha-Lipoic Acid, Chemopreventive, Chemotherapeutic, Kidney Cancer, Vitamin C: Intravenous

Arctigenin results in autophagic cell death and decreased ER expression in ER-positive human breast cancer cells.

Article Published Date : Feb 08, 2018
Study Type : In Vitro Study
Additional Links
Substances : Arctigenin : CK(160) : AC(107)
Diseases : Breast Cancer : CK(8297) : AC(3043)
Pharmacological Actions : Chemotherapeutic : CK(4390) : AC(1635)
Additional Keywords : Arctigenin, Breast Cancer : CK(113) : AC(34), Chemotherapeutic, Natural Substance/Drug Synergy : CK(1526) : AC(720)

Genistein intake mimicking Asian consumption patterns improved response of mammary tumors to tamoxifen therapy.

Article Published Date : Jan 31, 2017
Study Type : Animal Study
Additional Links
Substances : Genistein : CK(945) : AC(434)
Diseases : Breast Cancer : CK(8297) : AC(3043)
Pharmacological Actions : Chemotherapeutic : CK(4390) : AC(1635), Immunomodulatory : CK(6531) : AC(2360)
Additional Keywords : Breast Cancer : CK(113) : AC(34), Chemotherapeutic, Gene Expression Regulation : CK(1401) : AC(623), Genistein, Immunomodulatory

Iscador Qu inhibits doxorubicin-induced senescence of MCF7 cells.

Article Published Date : Jun 18, 2017
Study Type : In Vitro Study
Additional Links
Substances : Mistletoe : CK(243) : AC(61)
Diseases : Breast Cancer : CK(8297) : AC(3043)
Pharmacological Actions : Chemotherapeutic : CK(4390) : AC(1635)
Additional Keywords : Breast Cancer : CK(113) : AC(34), Chemotherapeutic, Chemotherapeutic Synergy: Doxorubicin : CK(347) : AC(266), Mistletoe

Low-molecular-weight fucoidan combined with chemotarget agents significantly improved the disease control rate.

Article Published Date : Apr 20, 2017
Study Type : Human Study
Additional Links
Substances : Fucoidan : CK(866) : AC(451)
Diseases : Colorectal Cancer : CK(4889) : AC(2276)
Pharmacological Actions : Chemotherapeutic : CK(4390) : AC(1635)
Additional Keywords : Chemotherapeutic, COLORECTAL CANCER, Fucoidan

Melatonin could be used as an adjuvant agent with rapamycin in head and neck cancers.

Article Published Date : Dec 15, 2017
Study Type : In Vitro Study
Additional Links
Substances : Melatonin : CK(2891) : AC(911)
Diseases : Head and Neck Cancer : CK(797) : AC(189)
Pharmacological Actions : Chemoprotective Agents : CK(4278) : AC(1621), Chemotherapeutic : CK(4390) : AC(1635)
Additional Keywords : Chemoprotective Agents, Chemotherapeutic, Head and Neck Cancer, melatonin, Natural Substance/Drug Synergy : CK(1526) : AC(720)

Neferine augments the therapeutic efficacy of cisplatin in human lung adenocarcinoma cells.

Article Published Date : Apr 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Lotus : CK(398) : AC(258)
Diseases : Lung Cancer : CK(3063) : AC(1429)
Pharmacological Actions : Autophagy Up-regulation : CK(838) : AC(559), Chemotherapeutic : CK(4390) : AC(1635)
Additional Keywords : Autophagy Up-regulation, Chemotherapeutic, Chemotherapeutic Synergy: Cisplatin : CK(430) : AC(339), Lotus, lung cancer

Neferine revealed higher toxicity toward paclitaxel and doxorubicin-resistant breast, lung or colon cancer cells.

Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Lotus : CK(398) : AC(258)
Diseases : Breast Cancer : CK(8297) : AC(3043), Cancers: Multi-Drug Resistant : CK(194) : AC(156), Colon Cancer : CK(1920) : AC(1203), Lung Cancer : CK(3063) : AC(1429)
Pharmacological Actions : Chemosensitizer : CK(1659) : AC(1271), Chemotherapeutic : CK(4390) : AC(1635)
Additional Keywords : Breast Cancer : CK(113) : AC(34), Cancers: Multi-Drug Resistant, Chemosensitizer, Chemotherapeutic, COLON CANCER, Lotus, lung cancer

Phytochemistry, pharmacology, and therapeutic uses of black seed (Nigella sativa).

Article Published Date : Sep 30, 2016
Study Type : Review
Additional Links
Substances : Nigella sativa (aka Black Seed) : CK(1912) : AC(494)
Pharmacological Actions : Analgesics : CK(9680) : AC(1472), Anti-Inflammatory Agents : CK(39739) : AC(15859), Anticonvulsants : CK(1163) : AC(299), Antihypertensive Agents : CK(7081) : AC(1029), Antimicrobial : CK(1577) : AC(790), Antioxidants : CK(34553) : AC(14500), Chemotherapeutic : CK(4390) : AC(1635), Hypoglycemic Agents : CK(9221) : AC(2076), Hypolipidemic : CK(9173) : AC(2038)
Additional Keywords : Analgesics, Anti-Inflammatory Agents, Anticonvulsants, Antihypertensive Agents, Antimicrobial, Antioxidants : CK(303) : AC(126), Chemotherapeutic, Nigella sativa (aka Black Seed), Plant Extracts : CK(18764) : AC(6783)

Structural optimization of mangiferin binding to cancer molecular targets.

Article Published Date : Mar 19, 2018
Study Type : In Vitro Study
Additional Links
Substances : Mangiferin : CK(376) : AC(223)
Diseases : Cancers: All : CK(36404) : AC(14363)
Pharmacological Actions : Chemotherapeutic : CK(4390) : AC(1635)
Additional Keywords : Cancers: All, Chemotherapeutic, Mangiferin

These results suggest fisetin in combination with gemcitabine as a candidate for use in improved anticancer regimens.

Article Published Date : Jan 10, 2016
Study Type : In Vitro Study
Additional Links
Substances : Fisetin : CK(441) : AC(275), Flavonoids : CK(4698) : AC(2176)
Diseases : Cholangiocarcinoma : CK(213) : AC(91)
Pharmacological Actions : Antiproliferative : CK(10001) : AC(7491), Apoptotic : CK(9585) : AC(7379), Chemotherapeutic : CK(4390) : AC(1635)
Additional Keywords : Antiproliferative : CK(75) : AC(61), Apoptotic, Chemotherapeutic, Chemotherapeutic Synergy: Gemcitabine : CK(126) : AC(85), Cholangiocarcinoma, Fisetin, Flavonoids

This study confirms the potential of modified pectin to improve chemotherapeutic cancer treatments.

Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Modified Citrus Pectin : CK(120) : AC(33)
Diseases : Liver Cancer : CK(3119) : AC(1641), Lung Cancer : CK(3063) : AC(1429)
Pharmacological Actions : Apoptotic : CK(9585) : AC(7379), Chemotherapeutic : CK(4390) : AC(1635)
Additional Keywords : Apoptotic, Chemotherapeutic, liver cancer, lung cancer, Modified Citrus Pectin

This study provides evidence that blueberries may be unique sources for anti-AML therapy.

Article Published Date : Dec 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Blueberry : CK(1151) : AC(334)
Diseases : Acute Myeloid Leukemia : CK(300) : AC(152)
Pharmacological Actions : Chemotherapeutic : CK(4390) : AC(1635)
Additional Keywords : Acute Myeloid Leukemia, Blueberry, Chemotherapeutic

Vitamin C with decitabine activates TET2 in leukemic cells and significantly improves overall survival in elderly patients with acute myeloid leukemia.

Article Published Date : Jan 01, 2018
Study Type : In Vitro Study
Additional Links
Substances : Vitamin C : CK(6066) : AC(1408), Vitamin C: Intravenous : CK(404) : AC(60)
Diseases : Acute Myeloid Leukemia : CK(300) : AC(152)
Pharmacological Actions : Antiproliferative : CK(10001) : AC(7491), Apoptotic : CK(9585) : AC(7379), Cell cycle arrest : CK(2120) : AC(1715), Chemotherapeutic : CK(4390) : AC(1635)
Additional Keywords : Acute Myeloid Leukemia, Antiproliferative : CK(75) : AC(61), Apoptotic, Cell cycle arrest, Chemotherapeutic, Natural Substance/Drug Synergy : CK(1526) : AC(720), Vitamin C : CK(48) : AC(13), Vitamin C: Intravenous

Vitamin K has been shown to suppress the growth of liver cancer cells.

Article Published Date : Oct 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Vitamin K2 : CK(560) : AC(91)
Diseases : Liver Cancer : CK(3119) : AC(1641)
Pharmacological Actions : Antineoplastic Agents : CK(2235) : AC(1468), Apoptotic : CK(9585) : AC(7379), Chemotherapeutic : CK(4390) : AC(1635)
Additional Keywords : Antineoplastic Agents : CK(78) : AC(35), Apoptotic, Chemotherapeutic, liver cancer, Natural Substance/Drug Synergy : CK(1526) : AC(720), Vitamin K2 : CK(16) : AC(6)

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