Results for DNA damage

Antioxidant activity of CAPE in vitro can protect human sperm deoxyribonucleic acid from oxidative damage.

Article Published Date : Jan 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Caffeic acid phenethyl ester : CK(58) : AC(30)
Diseases : DNA damage : CK(1482) : AC(545)
Pharmacological Actions : Antioxidants : CK(14410) : AC(5758), Genoprotective : CK(413) : AC(148)
Additional Keywords : Antioxidants : CK(1) : AC(1), Caffeic acid phenethyl ester, DNA damage, Genoprotective

Caffeine actually protected mice from genotoxicity and mutagenicity attributed to aging.

Article Published Date : May 18, 2017
Study Type : Animal Study
Additional Links
Substances : Caffeine : CK(245) : AC(40)
Diseases : Aging : CK(2716) : AC(676), DNA damage : CK(1482) : AC(545)
Pharmacological Actions : Antimutagenic Agents : CK(164) : AC(99), Genoprotective : CK(413) : AC(148)
Additional Keywords : Aging, Antimutagenic Agents, caffeine, DNA damage, Genoprotective

Grape seed extract were revealed to inhibit the oxidative induced DNA damage.

Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Anthocyanins : CK(610) : AC(230), Catechin : CK(565) : AC(191), Grape Seed Extract : CK(544) : AC(177)
Diseases : DNA damage : CK(1482) : AC(545)
Pharmacological Actions : Antioxidants : CK(14410) : AC(5758), Genoprotective : CK(413) : AC(148)
Additional Keywords : Anthocyanins : CK(7) : AC(6), Antioxidants : CK(1) : AC(1), Catechin, DNA damage, Genoprotective, Grape Seed Extract, Plant Extracts : CK(11762) : AC(4236)

Lactobacillus plantarum alleviates aflatoxins B1 and M1 induced disturbances in the intestinal genes expression and DNA fragmentation.

Article Published Date : Mar 20, 2018
Study Type : Animal Study
Additional Links
Substances : Lactobacillus plantarum : CK(415) : AC(113)
Diseases : DNA damage : CK(1482) : AC(545)
Pharmacological Actions : Genoprotective : CK(413) : AC(148), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(4357) : AC(1763)
Additional Keywords : DNA damage, Gene Expression Regulation : CK(431) : AC(214), Genoprotective, Lactobacillus plantarum, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Aflatoxin : CK(56) : AC(8)

Polysaccharide from Pleurotus nebrodensis induces apoptosis via a mitochondrial pathway in HepG2 cells.

Article Published Date : Dec 31, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Pleurotus nebrodensis : CK(3) : AC(2)
Diseases : DNA damage : CK(1482) : AC(545)
Pharmacological Actions : Antineoplastic Agents : CK(1594) : AC(982), Apoptotic : CK(5217) : AC(3846)
Additional Keywords : Antineoplastic Agents : CK(75) : AC(33), Apoptotic, DNA damage, Pleurotus nebrodensis, Polysaccharides : CK(5) : AC(3)

Talking on the phone for more than four hours per day and pocketing mobile phones could be a risk factor for sperm DNA fragmentation.

Article Published Date : Dec 01, 2013
Study Type : Human Study
Additional Links
Diseases : DNA damage : CK(1482) : AC(545), Infertility : CK(1359) : AC(316), Infertility: Male : CK(802) : AC(194), Sperm Quality: Low : CK(222) : AC(48)
Additional Keywords : Cell Phones, DNA damage, electromagnetic fields, electromagnetic frequencies, electromagnetic radiation, EMF, Male Infertility and Cellular Phones, Radio Frequency Electromagnetic Radiation Exposure
Anti Therapeutic Actions : Electromagnetic Field Harms : CK(4876) : AC(1003), Electromagnetic Radiation : CK(80) : AC(42), Microwave Radiation : CK(8) : AC(4), Mobile Phone Radiation : CK(64) : AC(13)
Problem Substances : Cell Phone Exposure : CK(19) : AC(4)
Adverse Pharmacological Actions : Genotoxic : CK(201) : AC(78)

These results demonstrat the radioprotective effect of folic acid supplementation on low dose ionizing radiation-induced genomic instability in vitro.

Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Folic Acid : CK(900) : AC(135)
Diseases : DNA damage : CK(1482) : AC(545)
Pharmacological Actions : Anti-Apoptotic : CK(1620) : AC(932), Radioprotective : CK(1247) : AC(406)
Additional Keywords : Anti-Apoptotic, DNA damage, folic acid, Radioprotective
Anti Therapeutic Actions : Low Dose Ionizing Radiation : CK(52) : AC(24)

These results indicate a chemopreventive potential of in vitro fermented hazelnuts.

Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Fermented Foods and Beverages : CK(1673) : AC(386), Hazelnut : CK(46) : AC(8)
Diseases : Colon Cancer : CK(1217) : AC(742), DNA damage : CK(1482) : AC(545)
Pharmacological Actions : Anticarcinogenic Agents : CK(1577) : AC(756), Antineoplastic Agents : CK(1594) : AC(982), Antiproliferative : CK(4773) : AC(3450), Apoptotic : CK(5217) : AC(3846)
Additional Keywords : Anticarcinogenic Agents, Antineoplastic Agents : CK(75) : AC(33), Antiproliferative : CK(65) : AC(52), Apoptotic, COLON CANCER, DNA damage, Fermented Foods and Beverages, Hazelnut

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