Results for DNA damage

Antioxidant activity of CAPE in vitro can protect human sperm deoxyribonucleic acid from oxidative damage.

Article Published Date : Jan 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Caffeic acid phenethyl ester : CK(284) : AC(172)
Diseases : DNA damage : CK(2301) : AC(842)
Pharmacological Actions : Antioxidants : CK(34551) : AC(14499), Genoprotective : CK(522) : AC(203)
Additional Keywords : Antioxidants : CK(303) : AC(126), Caffeic acid phenethyl ester, DNA damage, Genoprotective

Caffeine actually protected mice from genotoxicity and mutagenicity attributed to aging.

Article Published Date : May 18, 2017
Study Type : Animal Study
Additional Links
Substances : Caffeine : CK(478) : AC(89)
Diseases : Aging : CK(6221) : AC(1510), DNA damage : CK(2301) : AC(842)
Pharmacological Actions : Antimutagenic Agents : CK(218) : AC(138), Genoprotective : CK(522) : AC(203)
Additional Keywords : Aging, Antimutagenic Agents, caffeine, DNA damage, Genoprotective

Grape seed extract were revealed to inhibit the oxidative induced DNA damage.

Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Anthocyanins : CK(1599) : AC(492), Catechin : CK(965) : AC(313), Grape Seed Extract : CK(1058) : AC(331)
Diseases : DNA damage : CK(2301) : AC(842)
Pharmacological Actions : Antioxidants : CK(34551) : AC(14499), Genoprotective : CK(522) : AC(203)
Additional Keywords : Anthocyanins : CK(11) : AC(9), Antioxidants : CK(303) : AC(126), Catechin, DNA damage, Genoprotective, Grape Seed Extract, Plant Extracts : CK(18762) : AC(6782)

Lactobacillus plantarum alleviates aflatoxins B1 and M1 induced disturbances in the intestinal genes expression and DNA fragmentation.

Article Published Date : Mar 20, 2018
Study Type : Animal Study
Additional Links
Substances : Lactobacillus plantarum : CK(1008) : AC(308)
Diseases : DNA damage : CK(2301) : AC(842)
Pharmacological Actions : Genoprotective : CK(522) : AC(203), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(11697) : AC(4806)
Additional Keywords : DNA damage, Gene Expression Regulation : CK(1401) : AC(623), Genoprotective, Lactobacillus plantarum, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Aflatoxin : CK(230) : AC(87)

Polysaccharide from Pleurotus nebrodensis induces apoptosis via a mitochondrial pathway in HepG2 cells.

Article Published Date : Dec 31, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Pleurotus nebrodensis : CK(9) : AC(6)
Diseases : DNA damage : CK(2301) : AC(842)
Pharmacological Actions : Antineoplastic Agents : CK(2235) : AC(1468), Apoptotic : CK(9585) : AC(7379)
Additional Keywords : Antineoplastic Agents : CK(78) : AC(35), Apoptotic, DNA damage, Pleurotus nebrodensis, Polysaccharides : CK(1326) : AC(748)

Talking on the phone for more than four hours per day and pocketing mobile phones could be a risk factor for sperm DNA fragmentation.

Article Published Date : Dec 01, 2013
Study Type : Human Study
Additional Links
Diseases : DNA damage : CK(2301) : AC(842), Infertility : CK(2828) : AC(702), Infertility: Male : CK(1757) : AC(452), Sperm Quality: Low : CK(688) : AC(136)
Additional Keywords : Cell Phones, DNA damage, electromagnetic fields, electromagnetic frequencies, electromagnetic radiation, EMF, Male Infertility and Cellular Phones, Radio Frequency Electromagnetic Radiation Exposure
Anti Therapeutic Actions : Electromagnetic Field Harms : CK(4896) : AC(1009), Electromagnetic Radiation : CK(4987) : AC(989), Microwave Radiation : CK(1562) : AC(229), Mobile Phone Radiation : CK(2408) : AC(424)
Problem Substances : Cell Phone Exposure : CK(1393) : AC(226)
Adverse Pharmacological Actions : Genotoxic : CK(545) : AC(184)

These results demonstrat the radioprotective effect of folic acid supplementation on low dose ionizing radiation-induced genomic instability in vitro.

Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Folic Acid : CK(1317) : AC(206)
Diseases : DNA damage : CK(2301) : AC(842)
Pharmacological Actions : Anti-Apoptotic : CK(5568) : AC(3160), Radioprotective : CK(2398) : AC(713)
Additional Keywords : Anti-Apoptotic, DNA damage, folic acid, Radioprotective
Anti Therapeutic Actions : Low Dose Ionizing Radiation : CK(61) : AC(30)

These results indicate a chemopreventive potential of in vitro fermented hazelnuts.

Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Fermented Foods and Beverages : CK(3367) : AC(829), Hazelnut : CK(100) : AC(23)
Diseases : Colon Cancer : CK(1920) : AC(1203), DNA damage : CK(2301) : AC(842)
Pharmacological Actions : Anticarcinogenic Agents : CK(2152) : AC(1018), Antineoplastic Agents : CK(2235) : AC(1468), Antiproliferative : CK(10001) : AC(7491), Apoptotic : CK(9585) : AC(7379)
Additional Keywords : Anticarcinogenic Agents, Antineoplastic Agents : CK(78) : AC(35), Antiproliferative : CK(75) : AC(61), Apoptotic, COLON CANCER, DNA damage, Fermented Foods and Beverages, Hazelnut

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