Results for DNA damage

Antioxidant activity of CAPE in vitro can protect human sperm deoxyribonucleic acid from oxidative damage.

Article Published Date : Jan 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Caffeic acid phenethyl ester : CK(172) : AC(99)
Diseases : DNA damage : CK(1997) : AC(713)
Pharmacological Actions : Antioxidants : CK(21528) : AC(8856), Genoprotective : CK(477) : AC(177)
Additional Keywords : Antioxidants : CK(303) : AC(126), Caffeic acid phenethyl ester, DNA damage, Genoprotective

Caffeine actually protected mice from genotoxicity and mutagenicity attributed to aging.

Article Published Date : May 18, 2017
Study Type : Animal Study
Additional Links
Substances : Caffeine : CK(411) : AC(75)
Diseases : Aging : CK(3728) : AC(933), DNA damage : CK(1997) : AC(713)
Pharmacological Actions : Antimutagenic Agents : CK(164) : AC(99), Genoprotective : CK(477) : AC(177)
Additional Keywords : Aging, Antimutagenic Agents, caffeine, DNA damage, Genoprotective

Grape seed extract were revealed to inhibit the oxidative induced DNA damage.

Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Anthocyanins : CK(938) : AC(334), Catechin : CK(718) : AC(253), Grape Seed Extract : CK(746) : AC(243)
Diseases : DNA damage : CK(1997) : AC(713)
Pharmacological Actions : Antioxidants : CK(21528) : AC(8856), Genoprotective : CK(477) : AC(177)
Additional Keywords : Anthocyanins : CK(7) : AC(6), Antioxidants : CK(303) : AC(126), Catechin, DNA damage, Genoprotective, Grape Seed Extract, Plant Extracts : CK(14140) : AC(5210)

Lactobacillus plantarum alleviates aflatoxins B1 and M1 induced disturbances in the intestinal genes expression and DNA fragmentation.

Article Published Date : Mar 20, 2018
Study Type : Animal Study
Additional Links
Substances : Lactobacillus plantarum : CK(674) : AC(194)
Diseases : DNA damage : CK(1997) : AC(713)
Pharmacological Actions : Genoprotective : CK(477) : AC(177), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(6736) : AC(2815)
Additional Keywords : DNA damage, Gene Expression Regulation : CK(1141) : AC(501), Genoprotective, Lactobacillus plantarum, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Aflatoxin : CK(56) : AC(8)

Polysaccharide from Pleurotus nebrodensis induces apoptosis via a mitochondrial pathway in HepG2 cells.

Article Published Date : Dec 31, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Pleurotus nebrodensis : CK(3) : AC(2)
Diseases : DNA damage : CK(1997) : AC(713)
Pharmacological Actions : Antineoplastic Agents : CK(1847) : AC(1170), Apoptotic : CK(6986) : AC(5304)
Additional Keywords : Antineoplastic Agents : CK(78) : AC(35), Apoptotic, DNA damage, Pleurotus nebrodensis, Polysaccharides : CK(625) : AC(392)

Talking on the phone for more than four hours per day and pocketing mobile phones could be a risk factor for sperm DNA fragmentation.

Article Published Date : Dec 01, 2013
Study Type : Human Study
Additional Links
Diseases : DNA damage : CK(1997) : AC(713), Infertility : CK(2080) : AC(496), Infertility: Male : CK(1286) : AC(320), Sperm Quality: Low : CK(536) : AC(100)
Additional Keywords : Cell Phones, DNA damage, electromagnetic fields, electromagnetic frequencies, electromagnetic radiation, EMF, Male Infertility and Cellular Phones, Radio Frequency Electromagnetic Radiation Exposure
Anti Therapeutic Actions : Electromagnetic Field Harms : CK(4876) : AC(1003), Electromagnetic Radiation : CK(4965) : AC(982), Microwave Radiation : CK(1562) : AC(229), Mobile Phone Radiation : CK(2405) : AC(422)
Problem Substances : Cell Phone Exposure : CK(1393) : AC(226)
Adverse Pharmacological Actions : Genotoxic : CK(540) : AC(179)

These results demonstrat the radioprotective effect of folic acid supplementation on low dose ionizing radiation-induced genomic instability in vitro.

Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Folic Acid : CK(1047) : AC(168)
Diseases : DNA damage : CK(1997) : AC(713)
Pharmacological Actions : Anti-Apoptotic : CK(2905) : AC(1672), Radioprotective : CK(1668) : AC(521)
Additional Keywords : Anti-Apoptotic, DNA damage, folic acid, Radioprotective
Anti Therapeutic Actions : Low Dose Ionizing Radiation : CK(61) : AC(30)

These results indicate a chemopreventive potential of in vitro fermented hazelnuts.

Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Fermented Foods and Beverages : CK(2588) : AC(607), Hazelnut : CK(46) : AC(8)
Diseases : Colon Cancer : CK(1493) : AC(954), DNA damage : CK(1997) : AC(713)
Pharmacological Actions : Anticarcinogenic Agents : CK(1890) : AC(889), Antineoplastic Agents : CK(1847) : AC(1170), Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304)
Additional Keywords : Anticarcinogenic Agents, Antineoplastic Agents : CK(78) : AC(35), Antiproliferative : CK(65) : AC(52), Apoptotic, COLON CANCER, DNA damage, Fermented Foods and Beverages, Hazelnut

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