Results for Gut-liver axis

Anti-inflammatory activities of green tea catechins along the gut-liver axis in nonalcoholic fatty liver disease.

Article Published Date : Aug 11, 2020
Study Type : Review
Additional Links
Substances : Catechin : CK(718) : AC(253), Green Tea : CK(3450) : AC(1057)
Diseases : Lipopolysaccharide-Induced Toxicity : CK(1764) : AC(1073), Nonalcoholic fatty liver disease (NAFLD) : CK(1862) : AC(521)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), NF-kappaB Inhibitor : CK(3536) : AC(2098)
Additional Keywords : Gut-liver axis

Anti-obesity effects of Spirulina platensis protein hydrolysate by modulating brain-liver axis in high-fat diet fed mice

Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Spirulina : CK(660) : AC(203)
Diseases : Obesity : CK(6879) : AC(1686)
Additional Keywords : Anti-Obesity Agents : CK(2925) : AC(774), Gut-liver axis

Arctic berry extracts target the gut-liver axis to alleviate metabolic endotoxaemia, insulin resistance and hepatic steatosis.

Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Berries: All : CK(3814) : AC(1087), Blueberry : CK(721) : AC(250), Cloudberry : CK(16) : AC(5), Crowberry : CK(11) : AC(9), Lingonberry : CK(54) : AC(22)
Diseases : Endotoxemia : CK(219) : AC(91), Hepatic Steatosis : CK(325) : AC(124), Insulin Resistance : CK(3522) : AC(792), Obesity : CK(6879) : AC(1686)
Pharmacological Actions : Hepatoprotective : CK(5098) : AC(2264)
Additional Keywords : Gut-liver axis, Plant Extracts : CK(14140) : AC(5210)

Baicalin and the liver-gut system: Pharmacological bases explaining its therapeutic effects.

Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Flavonoids : CK(2352) : AC(870)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(1862) : AC(521)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Gastrointestinal Agents : CK(3145) : AC(843), NF-kappaB Inhibitor : CK(3536) : AC(2098)
Additional Keywords : Gut-liver axis

Bisphenol A exposure induces gut microbiota dysbiosis and consequent activation of gut-liver axis leading to hepatic steatosis.

Article Published Date : May 28, 2020
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(2930) : AC(882), Dysbiosis : CK(1527) : AC(422), Hepatic Steatosis : CK(325) : AC(124)
Additional Keywords : Gut-liver axis
Problem Substances : Bisphenol A : CK(3250) : AC(951)

Blueberry attenuated liver fibrosis, protected intestinal epithelial barrier, and maintained the homeostasis of the gut microbiota.

Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Blueberry : CK(721) : AC(250)
Diseases : Liver Fibrosis : CK(560) : AC(253)
Pharmacological Actions : Anti-Fibrotic : CK(924) : AC(463), Gastrointestinal Agents : CK(3145) : AC(843), Gastroprotective : CK(955) : AC(388), Hepatoprotective : CK(5098) : AC(2264)
Additional Keywords : Gut-liver axis

Coffee prevents fatty liver disease induced by a high-fat diet by modulating pathways of the gut-liver axis.

Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Coffee : CK(1460) : AC(180)
Diseases : High Fat Diet : CK(1267) : AC(602), Nonalcoholic fatty liver disease (NAFLD) : CK(1862) : AC(521)
Pharmacological Actions : Gastrointestinal Agents : CK(3145) : AC(843), Hepatoprotective : CK(5098) : AC(2264)
Additional Keywords : Gut-liver axis

Continued alcohol misuse in human cirrhosis is associated with an impaired gut-liver axis.

Article Published Date : Sep 18, 2017
Study Type : Human Study
Additional Links
Diseases : Alcohol Toxicity : CK(855) : AC(332), Cirrhosis: Liver : CK(568) : AC(120)
Additional Keywords : Gut-liver axis

Diallyl disulfide ameliorates ethanol-induced liver steatosis and inflammation by maintaining the fatty acid catabolism and regulating the gut-liver axis.

Article Published Date : May 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Organosulfur Compounds : CK(1077) : AC(481)
Diseases : Alcohol Toxicity : CK(855) : AC(332), Fatty Liver : CK(2522) : AC(701), Inflammation : CK(9572) : AC(3089)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Hepatoprotective : CK(5098) : AC(2264)
Additional Keywords : Gut-liver axis

Dietary approach and gut microbiota modulation for chronic hepatic encephalopathy in cirrhosis.

Article Published Date : Jun 26, 2019
Study Type : Review
Additional Links
Substances : Prebiotics : CK(349) : AC(90), Probiotics : CK(7680) : AC(1196)
Diseases : Cirrhosis : CK(650) : AC(133), Encephalopathy
Therapeutic Actions : Microbiota Transfer Therapy : CK(162) : AC(43)
Pharmacological Actions : Gastrointestinal Agents : CK(3145) : AC(843)
Additional Keywords : Gut-liver axis, Microbiota : CK(1256) : AC(346)

Eugenol alleviated nonalcoholic fatty liver disease.

Article Published Date : Apr 30, 2022
Study Type : Animal Study
Additional Links
Substances : Eugenol : CK(128) : AC(74)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(1862) : AC(521)
Pharmacological Actions : Gastrointestinal Agents : CK(3145) : AC(843), Hepatoprotective : CK(5098) : AC(2264), Hypolipidemic : CK(5358) : AC(1221)
Additional Keywords : Gut-brain Axis : CK(392) : AC(177), Gut-liver axis

Fermented ginseng improved alcohol liver injury in association with changes in the gut microbiota of mice.

Article Published Date : Aug 31, 2019
Study Type : Animal Study
Additional Links
Substances : Fermented Foods and Beverages : CK(2588) : AC(607), Ginseng : CK(2684) : AC(1192)
Diseases : Alcoholic Liver Disease : CK(389) : AC(168)
Pharmacological Actions : Gastrointestinal Agents : CK(3145) : AC(843), Hepatoprotective : CK(5098) : AC(2264)
Additional Keywords : Gut-liver axis

Folic acid ameliorates alcohol-induced liver injury via gut-liver axis homeostasis.

Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Folic Acid : CK(1047) : AC(168)
Diseases : Alcoholic Liver Disease : CK(389) : AC(168)
Pharmacological Actions : Gastrointestinal Agents : CK(3145) : AC(843), Hepatoprotective : CK(5098) : AC(2264)
Additional Keywords : Gut-liver axis

Glucopyranose from Pleurotus geesteranus prevent alcoholic liver diseases by regulating Nrf2/HO-1-TLR4/NF-κB signalling pathways and gut microbiota.

Article Published Date : Jan 19, 2022
Study Type : Animal Study
Additional Links
Substances : Medicinal Mushrooms : CK(1715) : AC(797)
Diseases : Alcoholic Liver Disease : CK(389) : AC(168)
Pharmacological Actions : Antioxidants : CK(21528) : AC(8856), Gastrointestinal Agents : CK(3145) : AC(843), Heme oxygenase-1 up-regulation : CK(624) : AC(373), Nrf2 activation : CK(1584) : AC(916)
Additional Keywords : Gut-liver axis

Gut-liver axis modulation of Panax notoginseng saponins in nonalcoholic fatty liver disease.

Article Published Date : Mar 02, 2021
Study Type : Animal Study
Additional Links
Substances : Panax Notoginseng : CK(225) : AC(100)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(1862) : AC(521)
Pharmacological Actions : Hepatoprotective : CK(5098) : AC(2264)
Additional Keywords : Gut-liver axis

Hepatoprotective effect of curcumin against bisphenol A-induced hepatic steatosis.

Article Published Date : Jun 29, 2022
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(5598) : AC(2788)
Diseases : Bisphenol Toxicity : CK(2930) : AC(882), Chemically-Induced Liver Damage : CK(1565) : AC(721)
Pharmacological Actions : Hepatoprotective : CK(5098) : AC(2264)
Additional Keywords : Gut-liver axis
Problem Substances : Bisphenol A : CK(3250) : AC(951)

Hepatoprotective effect of probiotic Lactobacillus rhamnosus GG in a model of alcoholic liver disease.

Article Published Date : Jun 25, 2019
Study Type : Animal Study
Additional Links
Substances : Lactobacillus rhamnosus GG : CK(466) : AC(98)
Diseases : Alcoholic Liver Disease : CK(389) : AC(168)
Pharmacological Actions : Gastrointestinal Agents : CK(3145) : AC(843), Hepatoprotective : CK(5098) : AC(2264)
Additional Keywords : Gut-liver axis

L. reuteri ZJ617 inhibits inflammatory and autophagy signaling pathways in gut-liver axis in piglet induced by lipopolysaccharide.

Article Published Date : Oct 12, 2021
Study Type : Animal Study
Additional Links
Substances : Lactobacillus reuteri : CK(473) : AC(77)
Diseases : Lipopolysaccharide-Induced Toxicity : CK(1764) : AC(1073)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334)
Additional Keywords : Gut-liver axis

Lactobacillus fermentum CQPC06 prevents non-alcoholic fatty liver disease by stabilizing the gut-liver axis.

Article Published Date : Oct 20, 2020
Study Type : Animal Study
Additional Links
Substances : Lactobacillus fermentum : CK(35) : AC(12)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(1862) : AC(521)
Pharmacological Actions : Gastrointestinal Agents : CK(3145) : AC(843), Hepatoprotective : CK(5098) : AC(2264)
Additional Keywords : Gut-liver axis

Lactobacillus plantarum 69-2 combined with galacto-oligosaccharides alleviates d-galactose-induced aging.

Article Published Date : Mar 09, 2021
Study Type : Animal Study
Additional Links
Substances : Galacto-oligosaccharides : CK(30) : AC(3), Lactobacillus plantarum : CK(674) : AC(194)
Diseases : Aging : CK(3728) : AC(933)
Pharmacological Actions : Antioxidants : CK(21528) : AC(8856), Gastrointestinal Agents : CK(3145) : AC(843), Hepatoprotective : CK(5098) : AC(2264), SIRT1 Activator : CK(39) : AC(23)
Additional Keywords : Gut-liver axis

Lycopene attenuates western-diet-induced cognitive deficits via improving glycolipid metabolism dysfunction and inflammatory responses in gut-liver-brain axis.

Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Lycopene : CK(886) : AC(249)
Diseases : Cognitive Decline/Dysfunction : CK(3236) : AC(654)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334)
Additional Keywords : Gut-brain Axis : CK(392) : AC(177), Gut-liver axis
Anti Therapeutic Actions : Western Diet : CK(416) : AC(121)

Morinda citrifolia extract prevents alcoholic fatty liver disease by improving gut health.

Article Published Date : Nov 30, 2022
Study Type : Animal Study
Additional Links
Substances : Noni : CK(206) : AC(93)
Diseases : Alcoholic Liver Disease : CK(389) : AC(168), Inflammation : CK(9572) : AC(3089)
Pharmacological Actions : Gastrointestinal Agents : CK(3145) : AC(843), Hepatoprotective : CK(5098) : AC(2264)
Additional Keywords : Gut-liver axis

Seabuckthorn polysaccharide ameliorates high-fat diet-induced obesity.

Article Published Date : Mar 06, 2022
Study Type : Animal Study
Additional Links
Substances : Sea buckthorn : CK(245) : AC(88)
Diseases : Obesity : CK(6879) : AC(1686)
Pharmacological Actions : Gastrointestinal Agents : CK(3145) : AC(843)
Additional Keywords : Anti-Obesity Agents : CK(2925) : AC(774), Gut-liver axis

sesamol could be a potential neuroprotective agent during aging process due to its beneficial effects on liver-brain axis.

Article Published Date : Nov 13, 2018
Study Type : Animal Study
Additional Links
Substances : Sesamol : CK(145) : AC(86)
Diseases : Brain: Oxidative Stress : CK(438) : AC(244), Cognitive Decline/Dysfunction : CK(3236) : AC(654)
Pharmacological Actions : Antioxidants : CK(21528) : AC(8856), Brain-derived neurotrophic factor modulator : CK(458) : AC(166), Interleukin-1 beta downregulation : CK(3041) : AC(1567), Neuroprotective Agents : CK(10404) : AC(4396), Nrf2 activation : CK(1584) : AC(916), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(6736) : AC(2815)
Additional Keywords : Gut-liver axis

Silibinin decreases hepatic glucose production through the activation of gut-brain-liver axis in diabetic rats.

Article Published Date : Sep 18, 2018
Study Type : Animal Study
Additional Links
Substances : Silibinin : CK(255) : AC(133)
Diseases : Diabetes Mellitus: Type 2 : CK(8552) : AC(1714), Obesity : CK(6879) : AC(1686)
Pharmacological Actions : Hypoglycemic Agents : CK(5366) : AC(1338)
Additional Keywords : Gut-liver axis

Sulforaphane ameliorates nonalcoholic fatty liver disease induced by high-fat and high-fructose diet.

Article Published Date : Jan 31, 2023
Study Type : Animal Study
Additional Links
Substances : Sulforaphane : CK(930) : AC(452)
Diseases : High Fat Diet : CK(1267) : AC(602), High Sugar Diet : CK(313) : AC(80), Inflammation : CK(9572) : AC(3089), Lipopolysaccharide-Induced Toxicity : CK(1764) : AC(1073), Nonalcoholic fatty liver disease (NAFLD) : CK(1862) : AC(521)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Hepatoprotective : CK(5098) : AC(2264)
Additional Keywords : Gut-liver axis, Risk Reduction : CK(15144) : AC(1708)

The links between the gut microbiome and non-alcoholic fatty liver disease (NAFLD).

Article Published Date : Jan 24, 2019
Study Type : Review
Additional Links
Substances : Probiotics : CK(7680) : AC(1196)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(1862) : AC(521)
Additional Keywords : Gut-liver axis

These results suggest a potential relevance of vitamin D as a therapeutic agent acting on the gut-liver axis.

Article Published Date : Jan 02, 2019
Study Type : Animal Study
Additional Links
Substances : Vitamin D : CK(8897) : AC(1260)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(1862) : AC(521)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Hepatoprotective : CK(5098) : AC(2264)
Additional Keywords : Gut-liver axis

This review will highlight the emerging role of the oral-gut-liver axis.

Article Published Date : Oct 04, 2017
Study Type : Review
Additional Links
Diseases : Dysbiosis : CK(1527) : AC(422), Liver Cirrhosis : CK(516) : AC(101)
Additional Keywords : Gut-liver axis

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