Results for Gut-liver axis

Alpha-linolenic acid ameliorates T2DM via reshaping gut-liver axis and inflammatory GPR120-NF-κB/NLRP3 pathway.

Article Published Date : Oct 31, 2025
Study Type : Animal Study
Additional Links
Diseases : Diabetes Mellitus: Type 2 : CK(13412) : AC(2666), Inflammation : CK(16913) : AC(5775), Insulin Resistance : CK(4958) : AC(1128)
Pharmacological Actions : Anti-Inflammatory Agents : CK(42224) : AC(16877), NF-kappaB Inhibitor : CK(6293) : AC(3650)
Additional Keywords : Gut-liver axis

Aluminum-induced oxidative stress promotes changes in the structure of the gut microbiota and liver deficiency.

Article Published Date : Aug 29, 2024
Study Type : Animal Study
Additional Links
Diseases : Aluminum Toxicity : CK(752) : AC(327), Inflammation : CK(16913) : AC(5775), Oxidative Stress : CK(15947) : AC(6229)
Additional Keywords : Gut-liver axis
Problem Substances : Aluminum : CK(1080) : AC(359)

Anti-inflammatory activities of green tea catechins along the gut-liver axis in nonalcoholic fatty liver disease.

Article Published Date : Aug 11, 2020
Study Type : Review
Additional Links
Substances : Catechin : CK(1032) : AC(331), Green Tea : CK(4545) : AC(1405)
Diseases : Lipopolysaccharide-Induced Toxicity : CK(3404) : AC(1979), Nonalcoholic fatty liver disease (NAFLD) : CK(3696) : AC(1036)
Pharmacological Actions : Anti-Inflammatory Agents : CK(42224) : AC(16877), NF-kappaB Inhibitor : CK(6293) : AC(3650)
Additional Keywords : Gut-liver axis

Anti-obesity effects of Spirulina platensis protein hydrolysate by modulating brain-liver axis in high-fat diet fed mice

Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Spirulina : CK(1018) : AC(293)
Diseases : Obesity : CK(11442) : AC(2769)
Additional Keywords : Anti-Obesity Agents : CK(5422) : AC(1374), Gut-liver axis

Arctic berry extracts target the gut-liver axis to alleviate metabolic endotoxaemia, insulin resistance and hepatic steatosis.

Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Berries: All : CK(5404) : AC(1663), Blueberry : CK(1186) : AC(347), Cloudberry : CK(16) : AC(5), Crowberry : CK(11) : AC(9), Lingonberry : CK(93) : AC(38)
Diseases : Endotoxemia : CK(378) : AC(134), Hepatic Steatosis : CK(436) : AC(181), Insulin Resistance : CK(4958) : AC(1128), Obesity : CK(11442) : AC(2769)
Pharmacological Actions : Hepatoprotective : CK(9540) : AC(4045)
Additional Keywords : Gut-liver axis, Plant Extracts : CK(19293) : AC(7058)

Astaxanthin, Haematococcus pluvialis and Haematococcus pluvialis residue alleviate liver injury in D-galactose-induced aging.

Article Published Date : Dec 31, 2023
Study Type : Animal Study
Additional Links
Substances : Astaxanthin : CK(1681) : AC(663)
Diseases : Aging : CK(6502) : AC(1588), Liver Damage : CK(4421) : AC(2000), Oxidative Stress : CK(15947) : AC(6229)
Additional Keywords : Gut-liver axis

Baicalin and the liver-gut system: Pharmacological bases explaining its therapeutic effects.

Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Flavonoids : CK(5088) : AC(2396)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(3696) : AC(1036)
Pharmacological Actions : Anti-Inflammatory Agents : CK(42224) : AC(16877), Gastrointestinal Agents : CK(8197) : AC(2474), NF-kappaB Inhibitor : CK(6293) : AC(3650)
Additional Keywords : Gut-liver axis

Bisphenol A exposure induces gut microbiota dysbiosis and consequent activation of gut-liver axis leading to hepatic steatosis.

Article Published Date : May 28, 2020
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(4436) : AC(1340), Dysbiosis : CK(2077) : AC(602), Hepatic Steatosis : CK(436) : AC(181)
Additional Keywords : Gut-liver axis
Problem Substances : Bisphenol A : CK(4590) : AC(1334)

Bisphenol F exposure induces depression-like changes.

Article Published Date : Jan 21, 2024
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(4436) : AC(1340), Depression : CK(10051) : AC(1856)
Additional Keywords : Gut-liver axis
Problem Substances : Bisphenol A : CK(4590) : AC(1334)

Blueberry attenuated liver fibrosis, protected intestinal epithelial barrier, and maintained the homeostasis of the gut microbiota.

Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Blueberry : CK(1186) : AC(347)
Diseases : Liver Fibrosis : CK(922) : AC(419)
Pharmacological Actions : Anti-Fibrotic : CK(2393) : AC(1138), Gastrointestinal Agents : CK(8197) : AC(2474), Gastroprotective : CK(1777) : AC(743), Hepatoprotective : CK(9540) : AC(4045)
Additional Keywords : Gut-liver axis

Coffee prevents fatty liver disease induced by a high-fat diet by modulating pathways of the gut-liver axis.

Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Coffee : CK(1670) : AC(210)
Diseases : High Fat Diet : CK(2124) : AC(1021), Nonalcoholic fatty liver disease (NAFLD) : CK(3696) : AC(1036)
Pharmacological Actions : Gastrointestinal Agents : CK(8197) : AC(2474), Hepatoprotective : CK(9540) : AC(4045)
Additional Keywords : Gut-liver axis

Combined nicotinamide riboside and magnesium-l-theanine protects against chronic stress-induced gut-liver injury by modulating NAD⁺ and metabolic pathways.

Article Published Date : Oct 02, 2025
Study Type : Animal Study
Additional Links
Substances : Magnesium : CK(2969) : AC(389), Vitamin B-3 (Niacin) : CK(400) : AC(72)
Diseases : Liver Damage : CK(4421) : AC(2000)
Pharmacological Actions : Hepatoprotective : CK(9540) : AC(4045)
Additional Keywords : Gut-liver axis

Continued alcohol misuse in human cirrhosis is associated with an impaired gut-liver axis.

Article Published Date : Sep 18, 2017
Study Type : Human Study
Additional Links
Diseases : Alcohol Toxicity : CK(1277) : AC(500), Cirrhosis: Liver : CK(740) : AC(217)
Additional Keywords : Gut-liver axis

Diallyl disulfide ameliorates ethanol-induced liver steatosis and inflammation by maintaining the fatty acid catabolism and regulating the gut-liver axis.

Article Published Date : May 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Organosulfur Compounds : CK(2174) : AC(1025)
Diseases : Alcohol Toxicity : CK(1279) : AC(501), Fatty Liver : CK(4592) : AC(1296), Inflammation : CK(16913) : AC(5775)
Pharmacological Actions : Anti-Inflammatory Agents : CK(42224) : AC(16877), Hepatoprotective : CK(9540) : AC(4045)
Additional Keywords : Gut-liver axis

Dietary approach and gut microbiota modulation for chronic hepatic encephalopathy in cirrhosis.

Article Published Date : Jun 26, 2019
Study Type : Review
Additional Links
Substances : Prebiotics : CK(441) : AC(113), Probiotics : CK(9943) : AC(1781)
Diseases : Cirrhosis : CK(826) : AC(232), Encephalopathy
Therapeutic Actions : Microbiota Transfer Therapy : CK(227) : AC(66)
Pharmacological Actions : Gastrointestinal Agents : CK(8197) : AC(2474)
Additional Keywords : Gut-liver axis, Microbiota : CK(1256) : AC(346)

Diosgenin alleviates nonalcoholic steatohepatitis through affecting liver-gut circulation.

Article Published Date : Dec 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Diosgenin : CK(245) : AC(146)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(3696) : AC(1036)
Pharmacological Actions : Hepatoprotective : CK(9540) : AC(4045)
Additional Keywords : Gut-liver axis

Effects of Pu-erh and Dian Hong tea polyphenols on the gut-liver axis.

Article Published Date : Jun 01, 2023
Study Type : Animal Study
Additional Links
Substances : Black Tea : CK(1050) : AC(265)
Diseases : Gastrointestinal Complaints : CK(111) : AC(22)
Pharmacological Actions : Antioxidants : CK(36502) : AC(15304)
Additional Keywords : Gut-liver axis

Eugenol alleviated nonalcoholic fatty liver disease.

Article Published Date : Apr 30, 2022
Study Type : Animal Study
Additional Links
Substances : Eugenol : CK(223) : AC(135)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(3696) : AC(1036)
Pharmacological Actions : Gastrointestinal Agents : CK(8197) : AC(2474), Hepatoprotective : CK(9540) : AC(4045), Hypolipidemic : CK(9570) : AC(2137)
Additional Keywords : Gut-brain Axis : CK(718) : AC(302), Gut-liver axis

Fecal microbiota transplantation from female donors restores gut permeability and reduces liver injury and inflammation in middle-aged male mice exposed to alcohol.

Article Published Date : Dec 31, 2023
Study Type : Animal Study
Additional Links
Diseases : Alcoholic Liver Disease : CK(639) : AC(299)
Therapeutic Actions : Microbiota Transfer Therapy : CK(227) : AC(66)
Pharmacological Actions : Hepatoprotective : CK(9540) : AC(4045)
Additional Keywords : Gut-liver axis

Fermented ginseng improved alcohol liver injury in association with changes in the gut microbiota of mice.

Article Published Date : Aug 31, 2019
Study Type : Animal Study
Additional Links
Substances : Fermented Foods and Beverages : CK(3460) : AC(853), Ginseng : CK(4207) : AC(1913)
Diseases : Alcoholic Liver Disease : CK(639) : AC(299)
Pharmacological Actions : Gastrointestinal Agents : CK(8197) : AC(2474), Hepatoprotective : CK(9540) : AC(4045)
Additional Keywords : Gut-liver axis

Folic acid ameliorates alcohol-induced liver injury via gut-liver axis homeostasis.

Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Folic Acid : CK(1332) : AC(210)
Diseases : Alcoholic Liver Disease : CK(639) : AC(299)
Pharmacological Actions : Gastrointestinal Agents : CK(8197) : AC(2474), Hepatoprotective : CK(9540) : AC(4045)
Additional Keywords : Gut-liver axis

Fu brick tea alleviates alcoholic liver injury by modulating the gut microbiota-liver axis.

Article Published Date : Sep 21, 2022
Study Type : Animal Study
Additional Links
Substances : Black Tea : CK(1050) : AC(265)
Diseases : Alcoholic Liver Disease : CK(639) : AC(299), Lipopolysaccharide-Induced Toxicity : CK(3404) : AC(1979)
Pharmacological Actions : Anti-Inflammatory Agents : CK(42224) : AC(16877), Antioxidants : CK(36502) : AC(15304), Gastrointestinal Agents : CK(8197) : AC(2474), Hepatoprotective : CK(9540) : AC(4045), NF-kappaB Inhibitor : CK(6293) : AC(3650)
Additional Keywords : Gut-liver axis

Fucoidan from Apostichopus japonicus ameliorates alcoholic liver disease by regulating gut-liver axis homeostasis.

Article Published Date : May 03, 2024
Study Type : Animal Study
Additional Links
Substances : Fucoidan : CK(867) : AC(452)
Diseases : Alcoholic Liver Disease : CK(639) : AC(299)
Pharmacological Actions : Hepatoprotective : CK(9540) : AC(4045)
Additional Keywords : Gut-liver axis

Ginsenoside Rh4 improves hepatic lipid metabolism and inflammation in a model of NAFLD.

Article Published Date : Jun 25, 2023
Study Type : Animal Study
Additional Links
Substances : Ginsenosides : CK(2648) : AC(1456)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(3696) : AC(1036)
Pharmacological Actions : Hepatoprotective : CK(9540) : AC(4045), Hypolipidemic : CK(9570) : AC(2137)
Additional Keywords : Gut-liver axis

Glucopyranose from Pleurotus geesteranus prevent alcoholic liver diseases by regulating Nrf2/HO-1-TLR4/NF-κB signalling pathways and gut microbiota.

Article Published Date : Jan 19, 2022
Study Type : Animal Study
Additional Links
Substances : Medicinal Mushrooms : CK(2674) : AC(1330)
Diseases : Alcoholic Liver Disease : CK(639) : AC(299)
Pharmacological Actions : Antioxidants : CK(36502) : AC(15304), Gastrointestinal Agents : CK(8197) : AC(2474), Heme oxygenase-1 up-regulation : CK(1424) : AC(826), Nrf2 activation : CK(3345) : AC(1903)
Additional Keywords : Gut-liver axis

Gut microbiota and liver metabolomics reveal the potential mechanism of Lactobacillus rhamnosus GG modulating the liver toxicity caused by polystyrene microplastics.

Article Published Date : Dec 27, 2023
Study Type : Animal Study
Additional Links
Substances : Lactobacillus rhamnosus GG : CK(704) : AC(155)
Diseases : Chemically-Induced Liver Damage : CK(2370) : AC(1124), Microplastic Toxicity : CK(1687) : AC(765)
Pharmacological Actions : Anti-Inflammatory Agents : CK(42224) : AC(16877), Gastrointestinal Agents : CK(8197) : AC(2474), Hepatoprotective : CK(9540) : AC(4045), Interleukin-6 Downregulation : CK(9848) : AC(3831), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(12294) : AC(5063)
Additional Keywords : Gut-liver axis

Gut microbiota participates in polystyrene microplastics-induced hepatic injuries.

Article Published Date : Aug 07, 2023
Study Type : Animal Study
Additional Links
Diseases : Chemically-Induced Liver Damage : CK(2370) : AC(1124), Inflammation : CK(16913) : AC(5775), Microplastic Toxicity : CK(1687) : AC(765)
Pharmacological Actions : Gastroprotective : CK(1777) : AC(743)
Additional Keywords : Gut-liver axis
Problem Substances : Polystyrene nanoparticles : CK(703) : AC(357)

Gut-liver axis mechanisms of Hippophae rhamnoides L. in non-alcoholic fatty liver disease prevention.

Article Published Date : Nov 30, 2025
Study Type : Animal Study
Additional Links
Substances : Sea buckthorn : CK(384) : AC(158)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(3696) : AC(1036)
Pharmacological Actions : Hepatoprotective : CK(9540) : AC(4045), Hypolipidemic : CK(9570) : AC(2137)
Additional Keywords : Gut-liver axis

Gut-liver axis modulation of Panax notoginseng saponins in nonalcoholic fatty liver disease.

Article Published Date : Mar 02, 2021
Study Type : Animal Study
Additional Links
Substances : Panax Notoginseng : CK(392) : AC(185)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(3696) : AC(1036)
Pharmacological Actions : Hepatoprotective : CK(9540) : AC(4045)
Additional Keywords : Gut-liver axis

Hepatoprotective and human gut microbiota modulation of polysaccharide-peptides in Pleurotus citrinopileatus.

Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Oyster Mushroom: Golden : CK(11) : AC(7)
Diseases : Liver Damage : CK(4421) : AC(2000)
Pharmacological Actions : Gastrointestinal Agents : CK(8197) : AC(2474), Hepatoprotective : CK(9540) : AC(4045)
Additional Keywords : Gut-liver axis, Polysaccharides : CK(1439) : AC(810)

Hepatoprotective effect of curcumin against bisphenol A-induced hepatic steatosis.

Article Published Date : Jun 29, 2022
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(8605) : AC(3791)
Diseases : Bisphenol Toxicity : CK(4436) : AC(1340), Chemically-Induced Liver Damage : CK(2370) : AC(1124)
Pharmacological Actions : Hepatoprotective : CK(9540) : AC(4045)
Additional Keywords : Gut-liver axis
Problem Substances : Bisphenol A : CK(4590) : AC(1334)

Hepatoprotective effect of probiotic Lactobacillus rhamnosus GG in a model of alcoholic liver disease.

Article Published Date : Jun 25, 2019
Study Type : Animal Study
Additional Links
Substances : Lactobacillus rhamnosus GG : CK(704) : AC(155)
Diseases : Alcoholic Liver Disease : CK(639) : AC(299)
Pharmacological Actions : Gastrointestinal Agents : CK(8197) : AC(2474), Hepatoprotective : CK(9540) : AC(4045)
Additional Keywords : Gut-liver axis

Hericium erinaceus polysaccharides ameliorate nonalcoholic fatty liver disease.

Article Published Date : Jun 30, 2024
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus) : CK(264) : AC(138)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(3696) : AC(1036)
Pharmacological Actions : Gastrointestinal Agents : CK(8197) : AC(2474)
Additional Keywords : Gut-liver axis, Polysaccharides : CK(1439) : AC(810)

Interaction between Per- and polyfluorinated substances (PFAS) and acetaminophen in disease exacerbation.

Article Published Date : Jan 02, 2024
Study Type : Review
Additional Links
Diseases : Acetaminophen (Tylenol) Toxicity : CK(1446) : AC(495), Autism Spectrum Disorders : CK(3752) : AC(584)
Additional Keywords : Gut-liver axis
Problem Substances : Acetaminophen, Paracetamol : CK(1400) : AC(428)

Intermittent fasting, especially when associated with coconut oil, had effects comparable with caloric restriction in modulating the parameters of the gut-liver axis.

Article Published Date : Jan 31, 2024
Study Type : Animal Study
Additional Links
Substances : Coconut Oil : CK(484) : AC(109)
Diseases : Obesity : CK(11442) : AC(2769)
Therapeutic Actions : Fasting/Caloric Restriction : CK(840) : AC(178)
Additional Keywords : Gut-liver axis

L. reuteri ZJ617 inhibits inflammatory and autophagy signaling pathways in gut-liver axis in piglet induced by lipopolysaccharide.

Article Published Date : Oct 12, 2021
Study Type : Animal Study
Additional Links
Substances : Lactobacillus reuteri : CK(623) : AC(127)
Diseases : Lipopolysaccharide-Induced Toxicity : CK(3404) : AC(1979)
Pharmacological Actions : Anti-Inflammatory Agents : CK(42224) : AC(16877)
Additional Keywords : Gut-liver axis

Lactobacillus fermentum CQPC06 prevents non-alcoholic fatty liver disease by stabilizing the gut-liver axis.

Article Published Date : Oct 20, 2020
Study Type : Animal Study
Additional Links
Substances : Lactobacillus fermentum : CK(226) : AC(96)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(3696) : AC(1036)
Pharmacological Actions : Gastrointestinal Agents : CK(8197) : AC(2474), Hepatoprotective : CK(9540) : AC(4045)
Additional Keywords : Gut-liver axis

Lactobacillus gasseri CKCC1913 mediated modulation of the gut-liver axis alleviated insulin resistance and liver damage induced by type 2 diabetes.

Article Published Date : Sep 18, 2023
Study Type : Animal Study
Additional Links
Substances : Lactobacillus gasseri : CK(209) : AC(46)
Diseases : Diabetes Mellitus: Type 2 : CK(13412) : AC(2666), Insulin Resistance : CK(4958) : AC(1128)
Pharmacological Actions : Antioxidants : CK(36502) : AC(15304), Hepatoprotective : CK(9540) : AC(4045)
Additional Keywords : Gut-liver axis

Lactobacillus plantarum 69-2 combined with galacto-oligosaccharides alleviates d-galactose-induced aging.

Article Published Date : Mar 09, 2021
Study Type : Animal Study
Additional Links
Substances : Galacto-oligosaccharides : CK(68) : AC(10), Lactobacillus plantarum : CK(1050) : AC(334)
Diseases : Aging : CK(6502) : AC(1588)
Pharmacological Actions : Antioxidants : CK(36502) : AC(15304), Gastrointestinal Agents : CK(8197) : AC(2474), Hepatoprotective : CK(9540) : AC(4045), SIRT1 Activator : CK(403) : AC(204)
Additional Keywords : Gut-liver axis

Lupeol improves bile acid metabolism and metabolic dysfunction-associated steatotic liver disease.

Article Published Date : Jun 16, 2024
Study Type : Animal Study
Additional Links
Substances : Lupeol : CK(122) : AC(68)
Diseases : Liver Disease : CK(392) : AC(120)
Pharmacological Actions : Hepatoprotective : CK(9540) : AC(4045)
Additional Keywords : Gut-liver axis

Lycium barbarum L. polyphenols improve HFD-induced NAFLD through liver and colon metabolism and intestinal microbiota.

Article Published Date : Oct 24, 2025
Study Type : Animal Study
Additional Links
Substances : Goji : CK(610) : AC(269), Polyphenols : CK(2939) : AC(1089)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(3696) : AC(1036)
Pharmacological Actions : Gastrointestinal Agents : CK(8197) : AC(2474), Hepatoprotective : CK(9540) : AC(4045)
Additional Keywords : Gut-liver axis

Lycopene attenuates western-diet-induced cognitive deficits via improving glycolipid metabolism dysfunction and inflammatory responses in gut-liver-brain axis.

Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Lycopene : CK(1268) : AC(373)
Diseases : Cognitive Decline/Dysfunction : CK(5716) : AC(1139)
Pharmacological Actions : Anti-Inflammatory Agents : CK(42224) : AC(16877)
Additional Keywords : Gut-brain Axis : CK(718) : AC(302), Gut-liver axis
Anti Therapeutic Actions : Western Diet : CK(601) : AC(151)

Melatonin improves cholestatic liver disease via the gut-liver axis.

Article Published Date : Dec 31, 2023
Study Type : Animal Study
Additional Links
Substances : Melatonin : CK(2954) : AC(923)
Diseases : Cholestasis : CK(167) : AC(55), Liver Cirrhosis : CK(960) : AC(238), Liver Disease : CK(392) : AC(120)
Pharmacological Actions : Gastrointestinal Agents : CK(8197) : AC(2474)
Additional Keywords : Gut-liver axis

microplastics and cadmium induced intestinal damage and liver inflammation in broilers.

Article Published Date : Mar 26, 2025
Study Type : Animal Study
Additional Links
Diseases : Cadmium Poisoning : CK(458) : AC(236), Microplastic Toxicity : CK(1687) : AC(765)
Additional Keywords : Gut-liver axis
Problem Substances : Cadmium : CK(619) : AC(278), Nano Plastic-and Micro-Particles : CK(1165) : AC(512)

Morinda citrifolia extract prevents alcoholic fatty liver disease by improving gut health.

Article Published Date : Nov 30, 2022
Study Type : Animal Study
Additional Links
Substances : Noni : CK(242) : AC(104)
Diseases : Alcoholic Liver Disease : CK(639) : AC(299), Inflammation : CK(16913) : AC(5775)
Pharmacological Actions : Gastrointestinal Agents : CK(8197) : AC(2474), Hepatoprotective : CK(9540) : AC(4045)
Additional Keywords : Gut-liver axis

MUP1 mediates urolithin A alleviation of chronic alcohol-related liver disease via gut-microbiota-liver axis.

Article Published Date : Dec 31, 2023
Study Type : Animal Study
Additional Links
Substances : Urolithin A : CK(271) : AC(137)
Diseases : Alcoholic Liver Disease : CK(639) : AC(299)
Pharmacological Actions : Hepatoprotective : CK(9540) : AC(4045)
Additional Keywords : Gut-liver axis

Obesogenic polystyrene microplastic exposures disrupt the gut-liver-adipose axis.

Article Published Date : Mar 25, 2024
Study Type : Animal Study
Additional Links
Diseases : Microplastic Toxicity : CK(1687) : AC(765)
Additional Keywords : Gut-liver axis
Problem Substances : Nano Plastic-and Micro-Particles : CK(1165) : AC(512), Polystyrene nanoparticles : CK(703) : AC(357)

Oral exposure to PLA microplastics induces time-dependent nanotoxicity via the gut-liver axis.

Article Published Date : Sep 04, 2025
Study Type : In Vitro Study
Additional Links
Diseases : Inflammation : CK(16913) : AC(5775), Liver Damage : CK(4421) : AC(2000), Microplastic Toxicity : CK(1687) : AC(765)
Additional Keywords : Gut-liver axis
Problem Substances : Nano Plastic-and Micro-Particles : CK(1165) : AC(512)
Adverse Pharmacological Actions : Gastrotoxic : CK(223) : AC(87), Inflammatory : CK(585) : AC(185)

Paeoniflorin recued hepatotoxicity under zinc oxide nanoparticles exposure.

Article Published Date : Sep 07, 2023
Study Type : Animal Study
Additional Links
Substances : Paeoniflorin : CK(658) : AC(397)
Diseases : Chemically-Induced Liver Damage : CK(2370) : AC(1124)
Pharmacological Actions : Hepatoprotective : CK(9540) : AC(4045)
Additional Keywords : Gut-liver axis
Problem Substances : Zinc Oxide : CK(30) : AC(15)

Phyllanthus emblica fruit improves obesity by reducing appetite and enhancing mucosal homeostasis.

Article Published Date : May 07, 2024
Study Type : Animal Study
Additional Links
Substances : Amla Fruit : CK(278) : AC(103)
Diseases : Obesity : CK(11442) : AC(2769)
Pharmacological Actions : Appetite Depressants : CK(84) : AC(14), Gastrointestinal Agents : CK(8197) : AC(2474)
Additional Keywords : Anti-Obesity Agents : CK(5422) : AC(1374), Gut-liver axis, Plant Extracts : CK(19293) : AC(7058)

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