Results for Gut-liver axis

Aluminum-induced oxidative stress promotes changes in the structure of the gut microbiota and liver deficiency.

Article Published Date : Aug 29, 2024
Study Type : Animal Study
Additional Links
Diseases : Aluminum Toxicity : CK(742) : AC(322), Inflammation : CK(16210) : AC(5545), Oxidative Stress : CK(14925) : AC(5797)
Additional Keywords : Gut-liver axis
Problem Substances : Aluminum : CK(1076) : AC(358)

Anti-inflammatory activities of green tea catechins along the gut-liver axis in nonalcoholic fatty liver disease.

Article Published Date : Aug 11, 2020
Study Type : Review
Additional Links
Substances : Catechin : CK(986) : AC(314), Green Tea : CK(4499) : AC(1389)
Diseases : Lipopolysaccharide-Induced Toxicity : CK(3262) : AC(1895), Nonalcoholic fatty liver disease (NAFLD) : CK(3530) : AC(982)
Pharmacological Actions : Anti-Inflammatory Agents : CK(40040) : AC(16009), NF-kappaB Inhibitor : CK(5994) : AC(3492)
Additional Keywords : Gut-liver axis

Anti-obesity effects of Spirulina platensis protein hydrolysate by modulating brain-liver axis in high-fat diet fed mice

Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Spirulina : CK(1017) : AC(292)
Diseases : Obesity : CK(11075) : AC(2689)
Additional Keywords : Anti-Obesity Agents : CK(5211) : AC(1328), Gut-liver axis

Arctic berry extracts target the gut-liver axis to alleviate metabolic endotoxaemia, insulin resistance and hepatic steatosis.

Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Berries: All : CK(5404) : AC(1533), Blueberry : CK(1151) : AC(334), Cloudberry : CK(16) : AC(5), Crowberry : CK(11) : AC(9), Lingonberry : CK(92) : AC(37)
Diseases : Endotoxemia : CK(359) : AC(127), Hepatic Steatosis : CK(434) : AC(180), Insulin Resistance : CK(4892) : AC(1103), Obesity : CK(11075) : AC(2689)
Pharmacological Actions : Hepatoprotective : CK(9158) : AC(3874)
Additional Keywords : Gut-liver axis, Plant Extracts : CK(18861) : AC(6829)

Astaxanthin, Haematococcus pluvialis and Haematococcus pluvialis residue alleviate liver injury in D-galactose-induced aging.

Article Published Date : Dec 31, 2023
Study Type : Animal Study
Additional Links
Substances : Astaxanthin : CK(1629) : AC(649)
Diseases : Aging : CK(6258) : AC(1524), Liver Damage : CK(4163) : AC(1901), Oxidative Stress : CK(14925) : AC(5797)
Additional Keywords : Gut-liver axis

Baicalin and the liver-gut system: Pharmacological bases explaining its therapeutic effects.

Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Flavonoids : CK(4730) : AC(2192)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(3530) : AC(982)
Pharmacological Actions : Anti-Inflammatory Agents : CK(40040) : AC(16009), Gastrointestinal Agents : CK(7717) : AC(2300), NF-kappaB Inhibitor : CK(5994) : AC(3492)
Additional Keywords : Gut-liver axis

Bisphenol A exposure induces gut microbiota dysbiosis and consequent activation of gut-liver axis leading to hepatic steatosis.

Article Published Date : May 28, 2020
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(4416) : AC(1331), Dysbiosis : CK(2044) : AC(589), Hepatic Steatosis : CK(434) : AC(180)
Additional Keywords : Gut-liver axis
Problem Substances : Bisphenol A : CK(4573) : AC(1325)

Bisphenol F exposure induces depression-like changes.

Article Published Date : Jan 21, 2024
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(4416) : AC(1331), Depression : CK(9685) : AC(1776)
Additional Keywords : Gut-liver axis
Problem Substances : Bisphenol A : CK(4573) : AC(1325)

Blueberry attenuated liver fibrosis, protected intestinal epithelial barrier, and maintained the homeostasis of the gut microbiota.

Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Blueberry : CK(1151) : AC(334)
Diseases : Liver Fibrosis : CK(889) : AC(403)
Pharmacological Actions : Anti-Fibrotic : CK(2228) : AC(1066), Gastrointestinal Agents : CK(7717) : AC(2300), Gastroprotective : CK(1715) : AC(712), Hepatoprotective : CK(9158) : AC(3874)
Additional Keywords : Gut-liver axis

Coffee prevents fatty liver disease induced by a high-fat diet by modulating pathways of the gut-liver axis.

Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Coffee : CK(1669) : AC(209)
Diseases : High Fat Diet : CK(2061) : AC(995), Nonalcoholic fatty liver disease (NAFLD) : CK(3530) : AC(982)
Pharmacological Actions : Gastrointestinal Agents : CK(7717) : AC(2300), Hepatoprotective : CK(9158) : AC(3874)
Additional Keywords : Gut-liver axis

Continued alcohol misuse in human cirrhosis is associated with an impaired gut-liver axis.

Article Published Date : Sep 18, 2017
Study Type : Human Study
Additional Links
Diseases : Alcohol Toxicity : CK(1245) : AC(486), Cirrhosis: Liver : CK(740) : AC(210)
Additional Keywords : Gut-liver axis

Diallyl disulfide ameliorates ethanol-induced liver steatosis and inflammation by maintaining the fatty acid catabolism and regulating the gut-liver axis.

Article Published Date : May 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Organosulfur Compounds : CK(2174) : AC(1025)
Diseases : Alcohol Toxicity : CK(1245) : AC(486), Fatty Liver : CK(4391) : AC(1230), Inflammation : CK(16210) : AC(5545)
Pharmacological Actions : Anti-Inflammatory Agents : CK(40040) : AC(16009), Hepatoprotective : CK(9158) : AC(3874)
Additional Keywords : Gut-liver axis

Dietary approach and gut microbiota modulation for chronic hepatic encephalopathy in cirrhosis.

Article Published Date : Jun 26, 2019
Study Type : Review
Additional Links
Substances : Prebiotics : CK(441) : AC(113), Probiotics : CK(9740) : AC(1712)
Diseases : Cirrhosis : CK(826) : AC(225), Encephalopathy
Therapeutic Actions : Microbiota Transfer Therapy : CK(227) : AC(66)
Pharmacological Actions : Gastrointestinal Agents : CK(7717) : AC(2300)
Additional Keywords : Gut-liver axis, Microbiota : CK(1256) : AC(346)

Diosgenin alleviates nonalcoholic steatohepatitis through affecting liver-gut circulation.

Article Published Date : Dec 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Diosgenin : CK(245) : AC(146)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(3530) : AC(982)
Pharmacological Actions : Hepatoprotective : CK(9158) : AC(3874)
Additional Keywords : Gut-liver axis

Effects of Pu-erh and Dian Hong tea polyphenols on the gut-liver axis.

Article Published Date : Jun 01, 2023
Study Type : Animal Study
Additional Links
Substances : Black Tea : CK(1050) : AC(265)
Diseases : Gastrointestinal Complaints : CK(111) : AC(22)
Pharmacological Actions : Antioxidants : CK(34832) : AC(14627)
Additional Keywords : Gut-liver axis

Eugenol alleviated nonalcoholic fatty liver disease.

Article Published Date : Apr 30, 2022
Study Type : Animal Study
Additional Links
Substances : Eugenol : CK(221) : AC(134)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(3530) : AC(982)
Pharmacological Actions : Gastrointestinal Agents : CK(7717) : AC(2300), Hepatoprotective : CK(9158) : AC(3874), Hypolipidemic : CK(9280) : AC(2053)
Additional Keywords : Gut-brain Axis : CK(687) : AC(290), Gut-liver axis

Fecal microbiota transplantation from female donors restores gut permeability and reduces liver injury and inflammation in middle-aged male mice exposed to alcohol.

Article Published Date : Dec 31, 2023
Study Type : Animal Study
Additional Links
Diseases : Alcoholic Liver Disease : CK(612) : AC(284)
Therapeutic Actions : Microbiota Transfer Therapy : CK(227) : AC(66)
Pharmacological Actions : Hepatoprotective : CK(9158) : AC(3874)
Additional Keywords : Gut-liver axis

Fermented ginseng improved alcohol liver injury in association with changes in the gut microbiota of mice.

Article Published Date : Aug 31, 2019
Study Type : Animal Study
Additional Links
Substances : Fermented Foods and Beverages : CK(3369) : AC(831), Ginseng : CK(4190) : AC(1902)
Diseases : Alcoholic Liver Disease : CK(612) : AC(284)
Pharmacological Actions : Gastrointestinal Agents : CK(7717) : AC(2300), Hepatoprotective : CK(9158) : AC(3874)
Additional Keywords : Gut-liver axis

Folic acid ameliorates alcohol-induced liver injury via gut-liver axis homeostasis.

Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Folic Acid : CK(1317) : AC(206)
Diseases : Alcoholic Liver Disease : CK(612) : AC(284)
Pharmacological Actions : Gastrointestinal Agents : CK(7717) : AC(2300), Hepatoprotective : CK(9158) : AC(3874)
Additional Keywords : Gut-liver axis

Fu brick tea alleviates alcoholic liver injury by modulating the gut microbiota-liver axis.

Article Published Date : Sep 21, 2022
Study Type : Animal Study
Additional Links
Substances : Black Tea : CK(1050) : AC(265)
Diseases : Alcoholic Liver Disease : CK(612) : AC(284), Lipopolysaccharide-Induced Toxicity : CK(3262) : AC(1895)
Pharmacological Actions : Anti-Inflammatory Agents : CK(40040) : AC(16009), Antioxidants : CK(34832) : AC(14627), Gastrointestinal Agents : CK(7717) : AC(2300), Hepatoprotective : CK(9158) : AC(3874), NF-kappaB Inhibitor : CK(5994) : AC(3492)
Additional Keywords : Gut-liver axis

Fucoidan from Apostichopus japonicus ameliorates alcoholic liver disease by regulating gut-liver axis homeostasis.

Article Published Date : May 03, 2024
Study Type : Animal Study
Additional Links
Substances : Fucoidan : CK(866) : AC(451)
Diseases : Alcoholic Liver Disease : CK(612) : AC(284)
Pharmacological Actions : Hepatoprotective : CK(9158) : AC(3874)
Additional Keywords : Gut-liver axis

Ginsenoside Rh4 improves hepatic lipid metabolism and inflammation in a model of NAFLD.

Article Published Date : Jun 25, 2023
Study Type : Animal Study
Additional Links
Substances : Ginsenosides : CK(2640) : AC(1452)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(3530) : AC(982)
Pharmacological Actions : Hepatoprotective : CK(9158) : AC(3874), Hypolipidemic : CK(9280) : AC(2053)
Additional Keywords : Gut-liver axis

Glucopyranose from Pleurotus geesteranus prevent alcoholic liver diseases by regulating Nrf2/HO-1-TLR4/NF-κB signalling pathways and gut microbiota.

Article Published Date : Jan 19, 2022
Study Type : Animal Study
Additional Links
Substances : Medicinal Mushrooms : CK(2674) : AC(1265)
Diseases : Alcoholic Liver Disease : CK(612) : AC(284)
Pharmacological Actions : Antioxidants : CK(34832) : AC(14627), Gastrointestinal Agents : CK(7717) : AC(2300), Heme oxygenase-1 up-regulation : CK(1345) : AC(785), Nrf2 activation : CK(3171) : AC(1810)
Additional Keywords : Gut-liver axis

Gut microbiota and liver metabolomics reveal the potential mechanism of Lactobacillus rhamnosus GG modulating the liver toxicity caused by polystyrene microplastics.

Article Published Date : Dec 27, 2023
Study Type : Animal Study
Additional Links
Substances : Lactobacillus rhamnosus GG : CK(660) : AC(147)
Diseases : Chemically-Induced Liver Damage : CK(2325) : AC(1099), Microplastic Toxicity : CK(1286) : AC(608)
Pharmacological Actions : Anti-Inflammatory Agents : CK(40040) : AC(16009), Gastrointestinal Agents : CK(7717) : AC(2300), Hepatoprotective : CK(9158) : AC(3874), Interleukin-6 Downregulation : CK(9412) : AC(3642), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(11778) : AC(4846)
Additional Keywords : Gut-liver axis

Gut microbiota participates in polystyrene microplastics-induced hepatic injuries.

Article Published Date : Aug 07, 2023
Study Type : Animal Study
Additional Links
Diseases : Chemically-Induced Liver Damage : CK(2325) : AC(1099), Inflammation : CK(16210) : AC(5545), Microplastic Toxicity : CK(1286) : AC(608)
Pharmacological Actions : Gastroprotective : CK(1715) : AC(712)
Additional Keywords : Gut-liver axis
Problem Substances : Polystyrene nanoparticles : CK(582) : AC(295)

Gut-liver axis modulation of Panax notoginseng saponins in nonalcoholic fatty liver disease.

Article Published Date : Mar 02, 2021
Study Type : Animal Study
Additional Links
Substances : Panax Notoginseng : CK(392) : AC(185)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(3530) : AC(982)
Pharmacological Actions : Hepatoprotective : CK(9158) : AC(3874)
Additional Keywords : Gut-liver axis

Hepatoprotective effect of curcumin against bisphenol A-induced hepatic steatosis.

Article Published Date : Jun 29, 2022
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(8139) : AC(3647)
Diseases : Bisphenol Toxicity : CK(4416) : AC(1331), Chemically-Induced Liver Damage : CK(2325) : AC(1099)
Pharmacological Actions : Hepatoprotective : CK(9158) : AC(3874)
Additional Keywords : Gut-liver axis
Problem Substances : Bisphenol A : CK(4573) : AC(1325)

Hepatoprotective effect of probiotic Lactobacillus rhamnosus GG in a model of alcoholic liver disease.

Article Published Date : Jun 25, 2019
Study Type : Animal Study
Additional Links
Substances : Lactobacillus rhamnosus GG : CK(660) : AC(147)
Diseases : Alcoholic Liver Disease : CK(612) : AC(284)
Pharmacological Actions : Gastrointestinal Agents : CK(7717) : AC(2300), Hepatoprotective : CK(9158) : AC(3874)
Additional Keywords : Gut-liver axis

Hericium erinaceus polysaccharides ameliorate nonalcoholic fatty liver disease.

Article Published Date : Jun 30, 2024
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus) : CK(262) : AC(136)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(3530) : AC(982)
Pharmacological Actions : Gastrointestinal Agents : CK(7717) : AC(2300)
Additional Keywords : Gut-liver axis, Polysaccharides : CK(1334) : AC(754)

Intermittent fasting, especially when associated with coconut oil, had effects comparable with caloric restriction in modulating the parameters of the gut-liver axis.

Article Published Date : Jan 31, 2024
Study Type : Animal Study
Additional Links
Substances : Coconut Oil : CK(478) : AC(106)
Diseases : Obesity : CK(11075) : AC(2689)
Therapeutic Actions : Fasting/Caloric Restriction : CK(830) : AC(177)
Additional Keywords : Gut-liver axis

L. reuteri ZJ617 inhibits inflammatory and autophagy signaling pathways in gut-liver axis in piglet induced by lipopolysaccharide.

Article Published Date : Oct 12, 2021
Study Type : Animal Study
Additional Links
Substances : Lactobacillus reuteri : CK(619) : AC(124)
Diseases : Lipopolysaccharide-Induced Toxicity : CK(3262) : AC(1895)
Pharmacological Actions : Anti-Inflammatory Agents : CK(40040) : AC(16009)
Additional Keywords : Gut-liver axis

Lactobacillus fermentum CQPC06 prevents non-alcoholic fatty liver disease by stabilizing the gut-liver axis.

Article Published Date : Oct 20, 2020
Study Type : Animal Study
Additional Links
Substances : Lactobacillus fermentum : CK(226) : AC(96)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(3530) : AC(982)
Pharmacological Actions : Gastrointestinal Agents : CK(7717) : AC(2300), Hepatoprotective : CK(9158) : AC(3874)
Additional Keywords : Gut-liver axis

Lactobacillus gasseri CKCC1913 mediated modulation of the gut-liver axis alleviated insulin resistance and liver damage induced by type 2 diabetes.

Article Published Date : Sep 18, 2023
Study Type : Animal Study
Additional Links
Substances : Lactobacillus gasseri : CK(209) : AC(46)
Diseases : Diabetes Mellitus: Type 2 : CK(12999) : AC(2591), Insulin Resistance : CK(4892) : AC(1103)
Pharmacological Actions : Antioxidants : CK(34832) : AC(14627), Hepatoprotective : CK(9158) : AC(3874)
Additional Keywords : Gut-liver axis

Lactobacillus plantarum 69-2 combined with galacto-oligosaccharides alleviates d-galactose-induced aging.

Article Published Date : Mar 09, 2021
Study Type : Animal Study
Additional Links
Substances : Galacto-oligosaccharides : CK(68) : AC(10), Lactobacillus plantarum : CK(1008) : AC(308)
Diseases : Aging : CK(6258) : AC(1524)
Pharmacological Actions : Antioxidants : CK(34832) : AC(14627), Gastrointestinal Agents : CK(7717) : AC(2300), Hepatoprotective : CK(9158) : AC(3874), SIRT1 Activator : CK(387) : AC(193)
Additional Keywords : Gut-liver axis

Lupeol improves bile acid metabolism and metabolic dysfunction-associated steatotic liver disease.

Article Published Date : Jun 16, 2024
Study Type : Animal Study
Additional Links
Substances : Lupeol : CK(122) : AC(68)
Diseases : Liver Disease : CK(390) : AC(119)
Pharmacological Actions : Hepatoprotective : CK(9158) : AC(3874)
Additional Keywords : Gut-liver axis

Lycopene attenuates western-diet-induced cognitive deficits via improving glycolipid metabolism dysfunction and inflammatory responses in gut-liver-brain axis.

Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Lycopene : CK(1267) : AC(372)
Diseases : Cognitive Decline/Dysfunction : CK(5542) : AC(1084)
Pharmacological Actions : Anti-Inflammatory Agents : CK(40040) : AC(16009)
Additional Keywords : Gut-brain Axis : CK(687) : AC(290), Gut-liver axis
Anti Therapeutic Actions : Western Diet : CK(601) : AC(151)

Melatonin improves cholestatic liver disease via the gut-liver axis.

Article Published Date : Dec 31, 2023
Study Type : Animal Study
Additional Links
Substances : Melatonin : CK(2902) : AC(913)
Diseases : Cholestasis : CK(163) : AC(53), Liver Cirrhosis : CK(919) : AC(230), Liver Disease : CK(390) : AC(119)
Pharmacological Actions : Gastrointestinal Agents : CK(7717) : AC(2300)
Additional Keywords : Gut-liver axis

microplastics and cadmium induced intestinal damage and liver inflammation in broilers.

Article Published Date : Mar 26, 2025
Study Type : Animal Study
Additional Links
Diseases : Cadmium Poisoning : CK(443) : AC(227), Microplastic Toxicity : CK(1286) : AC(608)
Additional Keywords : Gut-liver axis
Problem Substances : Cadmium : CK(604) : AC(270), Nano Plastic-and Micro-Particles : CK(768) : AC(357)

Morinda citrifolia extract prevents alcoholic fatty liver disease by improving gut health.

Article Published Date : Nov 30, 2022
Study Type : Animal Study
Additional Links
Substances : Noni : CK(242) : AC(104)
Diseases : Alcoholic Liver Disease : CK(612) : AC(284), Inflammation : CK(16210) : AC(5545)
Pharmacological Actions : Gastrointestinal Agents : CK(7717) : AC(2300), Hepatoprotective : CK(9158) : AC(3874)
Additional Keywords : Gut-liver axis

MUP1 mediates urolithin A alleviation of chronic alcohol-related liver disease via gut-microbiota-liver axis.

Article Published Date : Dec 31, 2023
Study Type : Animal Study
Additional Links
Substances : Urolithin A : CK(247) : AC(128)
Diseases : Alcoholic Liver Disease : CK(612) : AC(284)
Pharmacological Actions : Hepatoprotective : CK(9158) : AC(3874)
Additional Keywords : Gut-liver axis

Obesogenic polystyrene microplastic exposures disrupt the gut-liver-adipose axis.

Article Published Date : Mar 25, 2024
Study Type : Animal Study
Additional Links
Diseases : Microplastic Toxicity : CK(1286) : AC(608)
Additional Keywords : Gut-liver axis
Problem Substances : Nano Plastic-and Micro-Particles : CK(768) : AC(357), Polystyrene nanoparticles : CK(582) : AC(295)

Paeoniflorin recued hepatotoxicity under zinc oxide nanoparticles exposure.

Article Published Date : Sep 07, 2023
Study Type : Animal Study
Additional Links
Substances : Paeoniflorin : CK(600) : AC(364)
Diseases : Chemically-Induced Liver Damage : CK(2325) : AC(1099)
Pharmacological Actions : Hepatoprotective : CK(9158) : AC(3874)
Additional Keywords : Gut-liver axis
Problem Substances : Zinc Oxide : CK(30) : AC(15)

Phyllanthus emblica fruit improves obesity by reducing appetite and enhancing mucosal homeostasis.

Article Published Date : May 07, 2024
Study Type : Animal Study
Additional Links
Substances : Amla Fruit : CK(266) : AC(95)
Diseases : Obesity : CK(11075) : AC(2689)
Pharmacological Actions : Appetite Depressants : CK(84) : AC(14), Gastrointestinal Agents : CK(7717) : AC(2300)
Additional Keywords : Anti-Obesity Agents : CK(5211) : AC(1328), Gut-liver axis, Plant Extracts : CK(18861) : AC(6829)

Polystyrene nanoplastics exacerbate aflatoxin B1-induced hepatic injuries by modulating the gut-liver axis.

Article Published Date : Jul 19, 2024
Study Type : Animal Study
Additional Links
Diseases : Chemically-Induced Liver Damage : CK(2325) : AC(1099), Liver Damage: Aflatoxin-Induced : CK(106) : AC(49), Microplastic Toxicity : CK(1286) : AC(608)
Additional Keywords : Gut-liver axis, Increased Risk : CK(8788) : AC(1125)
Problem Substances : Nano Plastic-and Micro-Particles : CK(768) : AC(357), Polystyrene nanoparticles : CK(582) : AC(295)

Polystyrene nanoplastics induce intestinal and hepatic inflammation through activation of NF-κB/NLRP3 pathways and related gut-liver axis.

Article Published Date : Jul 19, 2024
Study Type : Animal Study
Additional Links
Diseases : Chemically-Induced Liver Damage : CK(2325) : AC(1099), Inflammation : CK(16210) : AC(5545), Microplastic Toxicity : CK(1286) : AC(608)
Additional Keywords : Gut-liver axis
Problem Substances : Nano Plastic-and Micro-Particles : CK(768) : AC(357), Polystyrene nanoparticles : CK(582) : AC(295)

Seabuckthorn polysaccharide ameliorates high-fat diet-induced obesity.

Article Published Date : Mar 06, 2022
Study Type : Animal Study
Additional Links
Substances : Sea buckthorn : CK(368) : AC(147)
Diseases : Obesity : CK(11075) : AC(2689)
Pharmacological Actions : Gastrointestinal Agents : CK(7717) : AC(2300)
Additional Keywords : Anti-Obesity Agents : CK(5211) : AC(1328), Gut-liver axis

sesamol could be a potential neuroprotective agent during aging process due to its beneficial effects on liver-brain axis.

Article Published Date : Nov 13, 2018
Study Type : Animal Study
Additional Links
Substances : Sesamol : CK(229) : AC(136)
Diseases : Brain: Oxidative Stress : CK(645) : AC(348), Cognitive Decline/Dysfunction : CK(5542) : AC(1084)
Pharmacological Actions : Antioxidants : CK(34832) : AC(14627), Brain-derived neurotrophic factor modulator : CK(751) : AC(284), Interleukin-1 beta downregulation : CK(6105) : AC(2965), Neuroprotective Agents : CK(20284) : AC(8048), Nrf2 activation : CK(3171) : AC(1810), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(11778) : AC(4846)
Additional Keywords : Gut-liver axis

Silibinin decreases hepatic glucose production through the activation of gut-brain-liver axis in diabetic rats.

Article Published Date : Sep 18, 2018
Study Type : Animal Study
Additional Links
Substances : Silibinin : CK(460) : AC(231)
Diseases : Diabetes Mellitus: Type 2 : CK(12999) : AC(2591), Obesity : CK(11075) : AC(2689)
Pharmacological Actions : Hypoglycemic Agents : CK(9365) : AC(2096)
Additional Keywords : Gut-liver axis

Sulforaphane ameliorates nonalcoholic fatty liver disease induced by high-fat and high-fructose diet.

Article Published Date : Jan 31, 2023
Study Type : Animal Study
Additional Links
Substances : Sulforaphane : CK(1345) : AC(631)
Diseases : High Fat Diet : CK(2061) : AC(995), High Sugar Diet : CK(480) : AC(125), Inflammation : CK(16210) : AC(5545), Lipopolysaccharide-Induced Toxicity : CK(3262) : AC(1895), Nonalcoholic fatty liver disease (NAFLD) : CK(3530) : AC(982)
Pharmacological Actions : Anti-Inflammatory Agents : CK(40040) : AC(16009), Hepatoprotective : CK(9158) : AC(3874)
Additional Keywords : Gut-liver axis, Risk Reduction : CK(17955) : AC(2008)

The improvement of intestinal dysbiosis and hepatic metabolic dysfunction in dextran sulfate sodium-induced colitis.

Article Published Date : Jul 31, 2023
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(8139) : AC(3647)
Diseases : Colitis : CK(1562) : AC(746), Inflammatory Bowel Diseases : CK(3268) : AC(948)
Pharmacological Actions : Gastrointestinal Agents : CK(7717) : AC(2300), Hepatoprotective : CK(9158) : AC(3874)
Additional Keywords : Gut-liver axis

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