Results for Interleukin-1 beta downregulation

Curcumin and piperine afforded a better neuroprotective effect compared to each of them alone.

Article Published Date : Nov 15, 2016
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(7239) : AC(3319), Piperine : CK(600) : AC(258)
Diseases : Brain Inflammation : CK(1784) : AC(928), Parkinson's Disease : CK(3012) : AC(1116)
Pharmacological Actions : Anti-Inflammatory Agents : CK(39737) : AC(15858), Interleukin-1 beta downregulation : CK(6063) : AC(2940), Interleukin-6 Downregulation : CK(9337) : AC(3613), Neuroprotective Agents : CK(20061) : AC(7949), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(11697) : AC(4806)
Additional Keywords : Anti-Inflammatory Agents, Brain Inflammation, CURCUMIN : CK(25) : AC(18), Interleukin-1 beta downregulation, Natural Substance Synergy : CK(1400) : AC(669), Parkinson's disease, Piperine

Piperine inhibited LPS-induced inflammatory response by activating Nrf2 signaling pathway.

Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Piperine : CK(600) : AC(258)
Diseases : Inflammation : CK(16108) : AC(5498), Lipopolysaccharide-Induced Toxicity : CK(3229) : AC(1875)
Pharmacological Actions : Anti-Inflammatory Agents : CK(39737) : AC(15858), Interleukin-1 beta downregulation : CK(6063) : AC(2940), Interleukin-6 Downregulation : CK(9337) : AC(3613), Nrf2 activation : CK(3156) : AC(1794), Prostaglandin PGE2 downregulation : CK(194) : AC(89), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(11697) : AC(4806)
Additional Keywords : Anti-Inflammatory Agents, Inflammation : CK(128) : AC(57), Interleukin-1 beta downregulation, Lipopolysaccharide-Induced Toxicity, Piperine

Piperine may become a potential therapeutic agent against bacterial sepsis.

Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Piperine : CK(600) : AC(258)
Diseases : Escherichia coli Infections : CK(603) : AC(450), Sepsis : CK(1436) : AC(491)
Pharmacological Actions : Anti-Inflammatory Agents : CK(39737) : AC(15858), Interleukin-1 beta downregulation : CK(6063) : AC(2940)
Additional Keywords : Anti-Inflammatory Agents, Dose Response : CK(1770) : AC(700), Escherichia coli Infections, Interleukin-1 beta downregulation, Piperine, sepsis

Resveratrol might be a promising therapeutic treatment for obesity-related osteoarthritis.

Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Resveratrol : CK(3228) : AC(1513)
Diseases : High Fat Diet : CK(2040) : AC(984), Osteoarthritis : CK(2225) : AC(627)
Pharmacological Actions : Anti-Inflammatory Agents : CK(39737) : AC(15858), Interleukin-1 beta downregulation : CK(6063) : AC(2940)
Additional Keywords : Anti-Inflammatory Agents, high fat diet, Interleukin-1 beta downregulation, osteoarthritis, RESVERATROL

The dietary ingestion of Aloe sterols protected against chronic UVB damage in mouse skin.

Article Published Date : Dec 19, 2016
Study Type : Animal Study
Additional Links
Substances : Aloe Vera : CK(940) : AC(254)
Diseases : Ultraviolet Radiation Induced Damage : CK(788) : AC(332)
Pharmacological Actions : Anti-Inflammatory Agents : CK(39737) : AC(15858), Interleukin-1 beta downregulation : CK(6063) : AC(2940), Matrix Metalloproteinase-12 (MMP-12) Inhibitor : CK(21) : AC(11), Matrix Metalloproteinase-13 (MMP-13) Inhibitor : CK(229) : AC(104), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(944) : AC(588), Matrix metalloproteinase-9 (MMP-9) inhibitor : CK(1141) : AC(720), Photoprotective : CK(778) : AC(304), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(11697) : AC(4806)
Additional Keywords : Aloe vera, Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Ultraviolet Radiation Induced Damage

These findings strongly suggest that the anti-inflammatory actions of Thymoquinone are caused by suppression of IRAK-linked AP-1/NF-κB pathways.

Article Published Date : Feb 19, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Thymoquinone : CK(1178) : AC(692)
Diseases : Inflammation : CK(16108) : AC(5498)
Pharmacological Actions : Anti-Inflammatory Agents : CK(39737) : AC(15858), Cyclooxygenase 2 Inhibitors : CK(2264) : AC(1327), Interleukin-1 beta downregulation : CK(6063) : AC(2940), Interleukin-6 Downregulation : CK(9337) : AC(3613), NF-kappaB Inhibitor : CK(5952) : AC(3464), Nitric Oxide Inhibitor : CK(705) : AC(356), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(11697) : AC(4806)
Additional Keywords : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Inflammation : CK(128) : AC(57), Interleukin-1 beta downregulation, thymoquinone

This study demonstrated that melatonin pretreatment attenuated lung ischaemia-reperfusion injury.

Article Published Date : Jan 14, 2018
Study Type : Animal Study
Additional Links
Substances : Melatonin : CK(2891) : AC(911)
Diseases : Ischemia : CK(626) : AC(325)
Pharmacological Actions : Anti-Inflammatory Agents : CK(39737) : AC(15858), Interleukin-1 beta downregulation : CK(6063) : AC(2940), NF-kappaB Inhibitor : CK(5952) : AC(3464), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(11697) : AC(4806)
Additional Keywords : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Ischemia, melatonin

Connect with GreenMedInfo