Results for Lipid Peroxidation

A lipid peroxidation product of DHA regulates mitochondrial homeostasis and reduces apoptosis to reduce reperfusion damage in a rat model of ischemic reperfusion.

Article Published Date : Jan 01, 2017
Study Type : Animal Study
Additional Links
Substances : DHA (Docosahexaenoic Acid) : CK(1285) : AC(244), Omega-3 Fatty Acids : CK(5687) : AC(772)
Diseases : Myocardial Infarction : CK(2204) : AC(535), Tachycardia : CK(107) : AC(20)
Pharmacological Actions : Anti-Apoptotic : CK(6074) : AC(3446), Cardioprotective : CK(9870) : AC(3118)
Additional Keywords : Cardiovascular Activity, Lipid Peroxidation, Mitochondria : CK(17) : AC(9), Omega-3 Fatty Acid Metabolism : CK(30) : AC(8)

Acute exposure to sunscreen containing titanium induces an adaptive response and oxidative stress in Mytillus galloprovincialis.

Article Published Date : Feb 28, 2018
Study Type : Animal Study
Additional Links
Diseases : Lipid Peroxidation : CK(2142) : AC(856), Oxidative Stress : CK(16086) : AC(6323)
Additional Keywords : Environmental Pollution, Lipid Peroxidation, oxidative stress, Sunscreen : CK(5) : AC(3), Titanium Dioxide
Problem Substances : Sunscreen : CK(100) : AC(21), Titanium Dioxide : CK(194) : AC(91)

Chrysin possesses restorative effect against paracetamol induced hepatotoxicity.

Article Published Date : Oct 31, 2017
Study Type : Animal Study
Additional Links
Substances : Chrysin : CK(447) : AC(276)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(1446) : AC(495), Lipid Peroxidation : CK(2142) : AC(856)
Pharmacological Actions : Anti-Apoptotic : CK(6074) : AC(3446), Antioxidants : CK(36635) : AC(15422), Hepatoprotective : CK(9584) : AC(4067)
Additional Keywords : Acetaminophen (Tylenol) Toxicity, Anti-Apoptotic, Antioxidants : CK(303) : AC(126), Chrysin, Hepatoprotective, Lipid Peroxidation
Problem Substances : Acetaminophen, Paracetamol : CK(1400) : AC(428)

Dandelion extracts with their antioxidant activity may be beneficial for diseases-associated with oxidative stress, and with changes of hemostasis.

Article Published Date : Jan 24, 2017
Study Type : In Vitro Study
Additional Links
Substances : Dandelion : CK(411) : AC(222)
Diseases : Hydrogen Peroxide Induced Toxicity : CK(444) : AC(359), Lipid Peroxidation : CK(2142) : AC(856), Oxidative Stress : CK(16086) : AC(6323)
Pharmacological Actions : Antioxidants : CK(36635) : AC(15422)
Additional Keywords : Antioxidants : CK(303) : AC(126), Dandelion, Hydrogen Peroxide Induced Toxicity, Lipid Peroxidation, oxidative stress, Plant Extracts : CK(19331) : AC(7085)

DHA and its lipid peroxide products exhibit anti-cancer activity through apoptotic and anti-proliferative mechanisms.

Article Published Date : May 01, 2008
Study Type : Review
Additional Links
Substances : DHA (Docosahexaenoic Acid) : CK(1285) : AC(244), Omega-3 Fatty Acids : CK(5687) : AC(772)
Diseases : Cancers
Pharmacological Actions : Antineoplastic Agents : CK(2366) : AC(1618), Antiproliferative : CK(10605) : AC(8041), Apoptotic : CK(10032) : AC(7858)
Additional Keywords : Anti-cancer, Lipid Peroxidation, Omega-3 Fatty Acid Metabolism : CK(30) : AC(8)

Fisetin exerts neuroprotection against aluminum chloride induced brain pathology.

Article Published Date : Feb 28, 2013
Study Type : Animal Study
Additional Links
Substances : Fisetin : CK(442) : AC(276)
Diseases : Aluminum Toxicity : CK(752) : AC(327), Lipid Peroxidation : CK(2142) : AC(856)
Pharmacological Actions : Antioxidants : CK(36635) : AC(15422), Neuroprotective Agents : CK(21418) : AC(8516)
Additional Keywords : aluminum toxicity, Antioxidants : CK(303) : AC(126), Fisetin, Lipid Peroxidation, Neuroprotective Agents
Problem Substances : Aluminum Chloride : CK(204) : AC(101)

Modification in the quantity, composition, and peroxidation of sebaceous lipid are believed to play a signficant role in acne pathogenesis.

Article Published Date : Jan 01, 2010
Study Type : Review
Additional Links
Diseases : Acne : CK(956) : AC(172), Inflammation : CK(17012) : AC(5842), Oxidative Stress : CK(16086) : AC(6323)
Additional Keywords : Acne Treatment, Lipid Peroxidation, natural acne remedies

Oligonol improves Aβ(25-35)-induced memory deficit and cognition impairment.

Article Published Date : Jun 30, 2014
Study Type : Animal Study
Additional Links
Substances : Lychee : CK(90) : AC(52)
Diseases : Lipid Peroxidation : CK(2142) : AC(856), Memory Disorders : CK(2598) : AC(679)
Pharmacological Actions : Antioxidants : CK(36635) : AC(15422), Neuroprotective Agents : CK(21418) : AC(8516), Nitric Oxide Inhibitor : CK(718) : AC(363)
Additional Keywords : Antioxidants : CK(303) : AC(126), Lipid Peroxidation, Lychee, Memory Disorders, Phytotherapy : CK(4064) : AC(1065), Plant Extracts : CK(19331) : AC(7085)

Oligonol is effective in protecting against DSS-induced mouse colitis and colon carcinogenesis.

Article Published Date : Jul 09, 2013
Study Type : Animal Study
Additional Links
Substances : Lychee : CK(90) : AC(52)
Diseases : Colitis : CK(1666) : AC(793), Colon Cancer : CK(1963) : AC(1231), Inflammation : CK(17012) : AC(5842), Lipid Peroxidation : CK(2142) : AC(856), Oxidative Stress : CK(16086) : AC(6323)
Pharmacological Actions : Anticarcinogenic Agents : CK(2159) : AC(1024), Antioxidants : CK(36635) : AC(15422), Cyclooxygenase 2 Inhibitors : CK(2338) : AC(1379), Interleukin-1 beta downregulation : CK(6516) : AC(3190), NF-kappaB Inhibitor : CK(6346) : AC(3715), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(12396) : AC(5136)
Additional Keywords : Colitis, COLON CANCER, Inflammation : CK(128) : AC(57), Lipid Peroxidation, Lychee, oxidative stress

Protective effect of polyphenols extract of adlay on hypercholesterolemia-induced oxidative stress.

Article Published Date : Jul 25, 2012
Study Type : Animal Study
Additional Links
Substances : Adlay : CK(128) : AC(79)
Diseases : Hypercholesterolemia : CK(2740) : AC(493), Lipid Peroxidation : CK(2142) : AC(856), Oxidative Stress : CK(16086) : AC(6323)
Pharmacological Actions : Anticholesteremic Agents : CK(4183) : AC(685), Antioxidants : CK(36635) : AC(15422), Malondialdehyde Down-regulation : CK(3135) : AC(1026), Superoxide Dismutase Up-regulation : CK(2575) : AC(996)
Additional Keywords : Adlay, Anticholesteremic Agents, Antioxidants : CK(303) : AC(126), Hypercholesterolemia, Lipid Peroxidation, oxidative stress

Sucralose induces biochemical responses, including neurotoxicity, in Daphnia magna.

Article Published Date : Dec 31, 2013
Study Type : Insect Study
Additional Links
Diseases : Lipid Peroxidation : CK(2142) : AC(856)
Additional Keywords : Lipid Peroxidation, Splenda, Sucralose
Problem Substances : Sucralose (aka Splenda) : CK(109) : AC(35)
Adverse Pharmacological Actions : Neurotoxic : CK(3044) : AC(757)

Tangeretin not only enhanced cisplatin’s cytotoxic actions in Hep3B and HCT-116 human cancer cells but could protect against its harmful effects.

Article Published Date : Oct 24, 2016
Study Type : In Vitro Study
Additional Links
Substances : Tangeretin : CK(206) : AC(114)
Diseases : Chemotherapy-Induced Toxicity: Cisplatin : CK(1318) : AC(637), Inflammation : CK(17012) : AC(5842), Lipid Peroxidation : CK(2142) : AC(856), Oxidative Stress : CK(16086) : AC(6323)
Pharmacological Actions : Anti-Inflammatory Agents : CK(42487) : AC(17069), Antioxidants : CK(36635) : AC(15422), Chemoprotective Agents : CK(4497) : AC(1724), Interleukin-10 upregulation : CK(1406) : AC(476), NF-kappaB Inhibitor : CK(6346) : AC(3715), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(12396) : AC(5136)
Additional Keywords : Chemotherapeutic Synergy: Cisplatin : CK(447) : AC(360), Chemotherapy-Induced Toxicity: Cisplatin, Inflammation : CK(128) : AC(57), Lipid Peroxidation, oxidative stress, Tangeretin

This in vitro study indicates that oxidation of docosahexanoic acid (DHA) into potentially damaging 4-hydroxy hexenal (HHE) exhibits less toxicity over time.

Article Published Date : Oct 05, 2018
Study Type : Human In Vitro
Additional Links
Substances : DHA (Docosahexaenoic Acid) : CK(1285) : AC(244), Omega-3 Fatty Acids : CK(5687) : AC(772)
Additional Keywords : Healthy Fats, Lipid Peroxidation

This study points out that the peroxidation products of eicosapentaenoic acid are anti-inflammatory and anti-thrombotic and, thus, cardioprotective.

Article Published Date : Jan 01, 2016
Study Type : Human Study
Additional Links
Substances : Eicosapentaenoic acid (EPA) : CK(1044) : AC(154), Omega-3 Fatty Acids : CK(5687) : AC(772)
Diseases : C-Reactive Protein : CK(4054) : AC(403), Cardiovascular Diseases : CK(17835) : AC(2979), Oxidative Stress : CK(16086) : AC(6323)
Pharmacological Actions : Anti-Inflammatory Agents : CK(42487) : AC(17069), Anti-thrombotic : CK(79) : AC(34), Cardioprotective : CK(9870) : AC(3118)
Additional Keywords : Lipid Peroxidation, omega-3 fatty acids

Thymoquinone use may decrease the destructive effects of methotrexate on testicular tissue of patients using this agent.

Article Published Date : Jul 31, 2011
Study Type : Animal Study
Additional Links
Substances : Thymoquinone : CK(1203) : AC(706)
Diseases : Drug Toxicity: Methotrexate : CK(215) : AC(106), Lipid Peroxidation : CK(2142) : AC(856), Oxidative Stress : CK(16086) : AC(6323)
Pharmacological Actions : Antioxidants : CK(36635) : AC(15422)
Additional Keywords : Antioxidants : CK(303) : AC(126), Drug Toxicity: Methotrexate, Lipid Peroxidation, oxidative stress, thymoquinone

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