Results for Lipid Peroxidation

A lipid peroxidation product of DHA regulates mitochondrial homeostasis and reduces apoptosis to reduce reperfusion damage in a rat model of ischemic reperfusion.

Article Published Date : Jan 01, 2017
Study Type : Animal Study
Additional Links
Substances : DHA (Docosahexaenoic Acid) : CK(1117) : AC(204), Omega-3 Fatty Acids : CK(4672) : AC(633)
Diseases : Myocardial Infarction : CK(1563) : AC(315), Tachycardia : CK(65) : AC(9)
Pharmacological Actions : Anti-Apoptotic : CK(2905) : AC(1672), Cardioprotective : CK(5377) : AC(1675)
Additional Keywords : Cardiovascular Activity, Lipid Peroxidation, Mitochondria : CK(3) : AC(3), Omega-3 Fatty Acid Metabolism : CK(20) : AC(2)

Acute exposure to sunscreen containing titanium induces an adaptive response and oxidative stress in Mytillus galloprovincialis.

Article Published Date : Feb 28, 2018
Study Type : Animal Study
Additional Links
Diseases : Lipid Peroxidation : CK(1632) : AC(631), Oxidative Stress : CK(9437) : AC(3550)
Additional Keywords : Environmental Pollution, Lipid Peroxidation, oxidative stress, Sunscreen : CK(1) : AC(1), Titanium Dioxide
Problem Substances : Sunscreen : CK(83) : AC(0), Titanium Dioxide : CK(67) : AC(31)

Chrysin possesses restorative effect against paracetamol induced hepatotoxicity.

Article Published Date : Oct 31, 2017
Study Type : Animal Study
Additional Links
Substances : Chrysin : CK(147) : AC(93)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(654) : AC(246), Lipid Peroxidation : CK(1632) : AC(631)
Pharmacological Actions : Anti-Apoptotic : CK(2905) : AC(1672), Antioxidants : CK(21528) : AC(8856), Hepatoprotective : CK(5098) : AC(2264)
Additional Keywords : Acetaminophen (Tylenol) Toxicity, Anti-Apoptotic, Antioxidants : CK(303) : AC(126), Chrysin, Hepatoprotective, Lipid Peroxidation
Problem Substances : Acetaminophen, Paracetamol : CK(546) : AC(202)

Dandelion extracts with their antioxidant activity may be beneficial for diseases-associated with oxidative stress, and with changes of hemostasis.

Article Published Date : Jan 24, 2017
Study Type : In Vitro Study
Additional Links
Substances : Dandelion : CK(262) : AC(134)
Diseases : Hydrogen Peroxide Induced Toxicity : CK(296) : AC(226), Lipid Peroxidation : CK(1632) : AC(631), Oxidative Stress : CK(9437) : AC(3550)
Pharmacological Actions : Antioxidants : CK(21528) : AC(8856)
Additional Keywords : Antioxidants : CK(303) : AC(126), Dandelion, Hydrogen Peroxide Induced Toxicity, Lipid Peroxidation, oxidative stress, Plant Extracts : CK(14140) : AC(5210)

DHA and its lipid peroxide products exhibit anti-cancer activity through apoptotic and anti-proliferative mechanisms.

Article Published Date : May 01, 2008
Study Type : Review
Additional Links
Substances : DHA (Docosahexaenoic Acid) : CK(1117) : AC(204), Omega-3 Fatty Acids : CK(4672) : AC(633)
Diseases : Cancers
Pharmacological Actions : Antineoplastic Agents : CK(1847) : AC(1170), Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304)
Additional Keywords : Anti-cancer, Lipid Peroxidation, Omega-3 Fatty Acid Metabolism : CK(20) : AC(2)

Fisetin exerts neuroprotection against aluminum chloride induced brain pathology.

Article Published Date : Feb 28, 2013
Study Type : Animal Study
Additional Links
Substances : Fisetin : CK(268) : AC(170)
Diseases : Aluminum Toxicity : CK(553) : AC(233), Lipid Peroxidation : CK(1632) : AC(631)
Pharmacological Actions : Antioxidants : CK(21528) : AC(8856), Neuroprotective Agents : CK(10404) : AC(4396)
Additional Keywords : aluminum toxicity, Antioxidants : CK(303) : AC(126), Fisetin, Lipid Peroxidation, Neuroprotective Agents
Problem Substances : Aluminum Chloride : CK(114) : AC(55)

Modification in the quantity, composition, and peroxidation of sebaceous lipid are believed to play a signficant role in acne pathogenesis.

Article Published Date : Jan 01, 2010
Study Type : Review
Additional Links
Diseases : Acne : CK(544) : AC(95), Inflammation : CK(9572) : AC(3089), Oxidative Stress : CK(9437) : AC(3550)
Additional Keywords : Acne Treatment, Lipid Peroxidation, natural acne remedies

Oligonol improves Aβ(25-35)-induced memory deficit and cognition impairment.

Article Published Date : Jun 30, 2014
Study Type : Animal Study
Additional Links
Substances : Lychee : CK(56) : AC(29)
Diseases : Lipid Peroxidation : CK(1632) : AC(631), Memory Disorders : CK(1067) : AC(339)
Pharmacological Actions : Antioxidants : CK(21528) : AC(8856), Neuroprotective Agents : CK(10404) : AC(4396), Nitric Oxide Inhibitor : CK(498) : AC(258)
Additional Keywords : Antioxidants : CK(303) : AC(126), Lipid Peroxidation, Lychee, Memory Disorders, Phytotherapy : CK(3062) : AC(812), Plant Extracts : CK(14140) : AC(5210)

Oligonol is effective in protecting against DSS-induced mouse colitis and colon carcinogenesis.

Article Published Date : Jul 09, 2013
Study Type : Animal Study
Additional Links
Substances : Lychee : CK(56) : AC(29)
Diseases : Colitis : CK(840) : AC(406), Colon Cancer : CK(1493) : AC(954), Inflammation : CK(9572) : AC(3089), Lipid Peroxidation : CK(1632) : AC(631), Oxidative Stress : CK(9437) : AC(3550)
Pharmacological Actions : Anticarcinogenic Agents : CK(1890) : AC(889), Antioxidants : CK(21528) : AC(8856), Cyclooxygenase 2 Inhibitors : CK(1589) : AC(926), Interleukin-1 beta downregulation : CK(3041) : AC(1567), NF-kappaB Inhibitor : CK(3536) : AC(2098), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(6736) : AC(2815)
Additional Keywords : Colitis, COLON CANCER, Inflammation : CK(128) : AC(57), Lipid Peroxidation, Lychee, oxidative stress

Protective effect of polyphenols extract of adlay on hypercholesterolemia-induced oxidative stress.

Article Published Date : Jul 25, 2012
Study Type : Animal Study
Additional Links
Substances : Adlay : CK(1) : AC(1)
Diseases : Hypercholesterolemia : CK(2333) : AC(408), Lipid Peroxidation : CK(1632) : AC(631), Oxidative Stress : CK(9437) : AC(3550)
Pharmacological Actions : Anticholesteremic Agents : CK(3078) : AC(530), Antioxidants : CK(21528) : AC(8856), Malondialdehyde Down-regulation : CK(2065) : AC(678), Superoxide Dismutase Up-regulation : CK(1403) : AC(551)
Additional Keywords : Adlay, Anticholesteremic Agents, Antioxidants : CK(303) : AC(126), Hypercholesterolemia, Lipid Peroxidation, oxidative stress

Sucralose induces biochemical responses, including neurotoxicity, in Daphnia magna.

Article Published Date : Dec 31, 2013
Study Type : Insect Study
Additional Links
Diseases : Lipid Peroxidation : CK(1632) : AC(631)
Additional Keywords : Lipid Peroxidation, Splenda, Sucralose
Problem Substances : Sucralose (aka Splenda) : CK(57) : AC(0)
Adverse Pharmacological Actions : Neurotoxic : CK(2424) : AC(562)

Tangeretin not only enhanced cisplatin’s cytotoxic actions in Hep3B and HCT-116 human cancer cells but could protect against its harmful effects.

Article Published Date : Oct 24, 2016
Study Type : In Vitro Study
Additional Links
Substances : Tangeretin : CK(38) : AC(24)
Diseases : Chemotherapy-Induced Toxicity: Cisplatin : CK(881) : AC(388), Inflammation : CK(9572) : AC(3089), Lipid Peroxidation : CK(1632) : AC(631), Oxidative Stress : CK(9437) : AC(3550)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856), Chemoprotective Agents : CK(2322) : AC(906), Interleukin-10 upregulation : CK(105) : AC(24), NF-kappaB Inhibitor : CK(3536) : AC(2098), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(6736) : AC(2815)
Additional Keywords : Chemotherapeutic Synergy: Cisplatin : CK(290) : AC(232), Chemotherapy-Induced Toxicity: Cisplatin, Inflammation : CK(128) : AC(57), Lipid Peroxidation, oxidative stress, Tangeretin

This in vitro study indicates that oxidation of docosahexanoic acid (DHA) into potentially damaging 4-hydroxy hexenal (HHE) exhibits less toxicity over time.

Article Published Date : Oct 05, 2018
Study Type : Human In Vitro
Additional Links
Substances : DHA (Docosahexaenoic Acid) : CK(1117) : AC(204), Omega-3 Fatty Acids : CK(4672) : AC(633)
Additional Keywords : Healthy Fats, Lipid Peroxidation

This study points out that the peroxidation products of eicosapentaenoic acid are anti-inflammatory and anti-thrombotic and, thus, cardioprotective.

Article Published Date : Jan 01, 2016
Study Type : Human Study
Additional Links
Substances : Eicosapentaenoic acid (EPA) : CK(974) : AC(140), Omega-3 Fatty Acids : CK(4672) : AC(633)
Diseases : C-Reactive Protein : CK(3134) : AC(310), Cardiovascular Diseases : CK(12780) : AC(1983), Oxidative Stress : CK(9437) : AC(3550)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Anti-thrombotic : CK(76) : AC(32), Cardioprotective : CK(5377) : AC(1675)
Additional Keywords : Lipid Peroxidation, omega-3 fatty acids

Thymoquinone use may decrease the destructive effects of methotrexate on testicular tissue of patients using this agent.

Article Published Date : Jul 31, 2011
Study Type : Animal Study
Additional Links
Substances : Thymoquinone : CK(774) : AC(451)
Diseases : Drug Toxicity: Methotrexate : CK(99) : AC(49), Lipid Peroxidation : CK(1632) : AC(631), Oxidative Stress : CK(9437) : AC(3550)
Pharmacological Actions : Antioxidants : CK(21528) : AC(8856)
Additional Keywords : Antioxidants : CK(303) : AC(126), Drug Toxicity: Methotrexate, Lipid Peroxidation, oxidative stress, thymoquinone

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