Results for Liver Damage: Drug-Induced

Lycopene is a natural compound that was able to inhibit the production of ROS and mitigate the damage caused by acetaminophen.

Article Published Date : Jan 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Carotenoids : CK(4371) : AC(1221), Lycopene : CK(1267) : AC(372)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355), Liver Damage: Drug-Induced : CK(635) : AC(277), Oxidative Stress : CK(14393) : AC(5534)
Pharmacological Actions : Antioxidants : CK(34009) : AC(14223), Hepatoprotective : CK(8852) : AC(3772), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(936) : AC(583)
Additional Keywords : Acetaminophen (Tylenol) Toxicity, Antioxidants : CK(303) : AC(126), CAROTENOIDS, Hepatoprotective, Liver Damage: Drug-Induced, lycopene, Matrix metalloproteinase-2 (MMP-2) inhibitor, oxidative stress
Problem Substances : Acetaminophen, Paracetamol : CK(859) : AC(296)

Lycopene pretreatment improves hepatotoxicity induced by acetaminophen in mice.

Article Published Date : Jan 31, 2017
Study Type : Animal Study
Additional Links
Substances : Lycopene : CK(1267) : AC(372)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355), Liver Damage: Drug-Induced : CK(635) : AC(277)
Pharmacological Actions : Anti-Inflammatory Agents : CK(38583) : AC(15403), Hepatoprotective : CK(8852) : AC(3772), Interleukin-1 beta downregulation : CK(5903) : AC(2868), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(936) : AC(583)
Additional Keywords : Acetaminophen (Tylenol) Toxicity, Anti-Inflammatory Agents, Hepatoprotective, Liver Damage: Drug-Induced, lycopene
Problem Substances : Acetaminophen, Paracetamol : CK(859) : AC(296)

Protective effects of combined β-caryophyllene and silymarin against ketoprofen-induced hepatotoxicity.

Article Published Date : Jun 30, 2016
Study Type : Animal Study
Additional Links
Substances : Beta-Caryophyllene : CK(171) : AC(92), Silymarin : CK(453) : AC(111)
Diseases : Liver Damage: Drug-Induced : CK(635) : AC(277)
Pharmacological Actions : Hepatoprotective : CK(8852) : AC(3772)
Additional Keywords : Beta-Caryophyllene, Hepatoprotective, Liver Damage: Drug-Induced, Plant Extracts : CK(18617) : AC(6734), SILYMARIN
Problem Substances : Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) : CK(3217) : AC(649)

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