Results for NF-kappaB Inhibitor

Allicin provides protection against arsenic trioxide induced liver injury.

Article Published Date : Feb 28, 2017
Study Type : Animal Study
Additional Links
Substances : Allicin : CK(238) : AC(128)
Diseases : Arsenic Poisoning : CK(243) : AC(91), Oxidative Stress : CK(9437) : AC(3550)
Pharmacological Actions : Antioxidants : CK(21528) : AC(8856), NF-kappaB Inhibitor : CK(3536) : AC(2098), Nrf2 activation : CK(1584) : AC(916)
Additional Keywords : Allicin, Antioxidants : CK(303) : AC(126), Arsenic Poisoning, NF-kappaB Inhibitor, Nrf2 activation, oxidative stress
Problem Substances : Arsenic Trioxide : CK(6) : AC(4)

Arctigenin protects against ultraviolet-A-induced damage to stemness.

Article Published Date : Feb 24, 2018
Study Type : In Vitro Study
Additional Links
Substances : Arctigenin : CK(120) : AC(79)
Diseases : Ultraviolet Radiation Induced Damage : CK(461) : AC(215)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), NF-kappaB Inhibitor : CK(3536) : AC(2098), Photoprotective : CK(446) : AC(198)
Additional Keywords : Anti-Inflammatory Agents, Arctigenin, NF-kappaB Inhibitor, Photoprotective, Ultraviolet Radiation Induced Damage

Baicalein could be a lead compound for the modulation of inflammatory diseases as well as certain cancers.

Article Published Date : Oct 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Baicalein : CK(184) : AC(112)
Diseases : Cervical Cancer : CK(756) : AC(422), Inflammation : CK(9572) : AC(3089)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), NF-kappaB Inhibitor : CK(3536) : AC(2098), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(6736) : AC(2815)
Additional Keywords : Anti-Inflammatory Agents, Baicalein, Cervical Cancer, Gene Expression Regulation : CK(1141) : AC(501), NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Carnosic acid attenuates RANKL-induced oxidative stress and osteoclastogenesis.

Article Published Date : Sep 30, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Carnosic Acid : CK(121) : AC(82)
Diseases : Bone Diseases : CK(18) : AC(6)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856), NF-kappaB Inhibitor : CK(3536) : AC(2098), Osteoprotective : CK(971) : AC(351)
Additional Keywords : Anti-Inflammatory Agents, Antioxidants : CK(303) : AC(126), Bone Diseases, Carnosic Acid, NF-kappaB Inhibitor, Osteoprotective

Moracin M inhibited airway inflammation in vitro and in vivo, and it has therapeutic potential for treating lung inflammatory disorders.

Article Published Date : Jul 14, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : White Mulberry : CK(140) : AC(54)
Diseases : Experimental Lung Inflammation : CK(10) : AC(1), Inflammation : CK(9572) : AC(3089)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), NF-kappaB Inhibitor : CK(3536) : AC(2098)
Additional Keywords : Anti-Inflammatory Agents, Experimental Lung Inflammation, Inflammation : CK(128) : AC(57), NF-kappaB Inhibitor, White Mulberry

Oligonol has protective activity against oxidative stress-induced inflammation.

Article Published Date : Mar 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Lychee : CK(56) : AC(29)
Diseases : Inflammation : CK(9572) : AC(3089), Oxidative Stress : CK(9437) : AC(3550)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856), Cyclooxygenase Inhibitors : CK(74) : AC(42), NF-kappaB Inhibitor : CK(3536) : AC(2098)
Additional Keywords : Anti-Inflammatory Agents, Antioxidants : CK(303) : AC(126), Cyclooxygenase Inhibitors, Inflammation : CK(128) : AC(57), Lychee, NF-kappaB Inhibitor, oxidative stress

Phloretin inhibits phorbol ester-induced tumor promotion and expression of cyclooxygenase-2 in mouse skin.

Article Published Date : Feb 29, 2012
Study Type : Animal Study
Additional Links
Substances : Phloretin : CK(177) : AC(101)
Diseases : Skin Cancer : CK(1429) : AC(636)
Pharmacological Actions : Anticarcinogenic Agents : CK(1890) : AC(889), Cyclooxygenase 2 Inhibitors : CK(1589) : AC(926), NF-kappaB Inhibitor : CK(3536) : AC(2098)
Additional Keywords : Anticarcinogenic Agents, Cyclooxygenase 2 Inhibitors, NF-kappaB Inhibitor, Phloretin, skin cancer

Piceatannol provides remarkable renoprotection in diabetes by abrogating oxidative stress and NF-kB activation.

Article Published Date : Nov 25, 2016
Study Type : Animal Study
Additional Links
Substances : Piceatannol : CK(23) : AC(0)
Diseases : Diabetic Nephropathy : CK(707) : AC(277)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856), NF-kappaB Inhibitor : CK(3536) : AC(2098), Renoprotective : CK(2404) : AC(1075)
Additional Keywords : Anti-Inflammatory Agents, Antioxidants : CK(303) : AC(126), Diabetic Nephropathy, NF-kappaB Inhibitor, Piceatannol, Renoprotective

Pomegranate fruit extract significantly inhibits lung tumorigenesis in A/J mice.

Article Published Date : Mar 31, 2007
Study Type : Animal Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Benzo[a]pyrene-induced Toxicity : CK(124) : AC(75), Lung Cancer : CK(2308) : AC(999)
Pharmacological Actions : Anticarcinogenic Agents : CK(1890) : AC(889), Chemopreventive : CK(5374) : AC(1717), NF-kappaB Inhibitor : CK(3536) : AC(2098)
Additional Keywords : Anticarcinogenic Agents, Chemopreventive, lung cancer, NF-kappaB Inhibitor, Phytotherapy : CK(3062) : AC(812), Plant Extracts : CK(14140) : AC(5210), pomegranate
Problem Substances : Benzo(a)pyrene : CK(19) : AC(10)

This report confirms the anti-inflammatory potential of this traditionally employed herbal medicine in vitro.

Article Published Date : Dec 31, 2011
Study Type : In Vitro Study
Additional Links
Substances : Justicia gendarussa : CK(1) : AC(1)
Diseases : Inflammation : CK(9572) : AC(3089), Lipopolysaccharide-Induced Toxicity : CK(1764) : AC(1073)
Pharmacological Actions : 5-Lipoxygenase Inhibitor : CK(35) : AC(21), Anti-Inflammatory Agents : CK(20859) : AC(8334), Cyclooxygenase 2 Inhibitors : CK(1589) : AC(926), Interleukin-6 Downregulation : CK(5029) : AC(1994), NF-kappaB Inhibitor : CK(3536) : AC(2098)
Additional Keywords : 5-Lipoxygenase Inhibitor, Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Inflammation : CK(128) : AC(57), Interleukin-6 Downregulation, Justicia gendarussa, Lipopolysaccharide-Induced Toxicity, NF-kappaB Inhibitor, Plant Extracts : CK(14140) : AC(5210)

Vitamin K2 may be a potential therapeutic agent in the treatment of prostate cancer.

Article Published Date : Dec 31, 2012
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Vitamin K2 : CK(462) : AC(74)
Diseases : Prostate Cancer : CK(2407) : AC(834)
Pharmacological Actions : Angiogenesis Inhibitors : CK(488) : AC(296), Anti-Inflammatory Agents : CK(20859) : AC(8334), Anti-metastatic : CK(1972) : AC(1481), Apoptotic : CK(6986) : AC(5304), NF-kappaB Inhibitor : CK(3536) : AC(2098)
Additional Keywords : Angiogenesis Inhibitors, Anti-Inflammatory Agents, Anti-metastatic, Apoptotic, NF-kappaB Inhibitor, prostate cancer, Vitamin K2 : CK(1) : AC(1)

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