Results for NF-kappaB Inhibitor

Allicin provides protection against arsenic trioxide induced liver injury.

Article Published Date : Feb 28, 2017
Study Type : Animal Study
Additional Links
Substances : Allicin : CK(361) : AC(197)
Diseases : Arsenic Poisoning : CK(414) : AC(137), Oxidative Stress : CK(16183) : AC(6369)
Pharmacological Actions : Antioxidants : CK(36960) : AC(15513), NF-kappaB Inhibitor : CK(6453) : AC(3744), Nrf2 activation : CK(3405) : AC(1942)
Additional Keywords : Allicin, Antioxidants : CK(303) : AC(126), Arsenic Poisoning, NF-kappaB Inhibitor, Nrf2 activation, oxidative stress
Problem Substances : Arsenic Trioxide : CK(45) : AC(27)

Arctigenin protects against ultraviolet-A-induced damage to stemness.

Article Published Date : Feb 24, 2018
Study Type : In Vitro Study
Additional Links
Substances : Arctigenin : CK(180) : AC(118)
Diseases : Ultraviolet Radiation Induced Damage : CK(830) : AC(355)
Pharmacological Actions : Anti-Inflammatory Agents : CK(42985) : AC(17177), NF-kappaB Inhibitor : CK(6453) : AC(3744), Photoprotective : CK(809) : AC(319)
Additional Keywords : Anti-Inflammatory Agents, Arctigenin, NF-kappaB Inhibitor, Photoprotective, Ultraviolet Radiation Induced Damage

Baicalein could be a lead compound for the modulation of inflammatory diseases as well as certain cancers.

Article Published Date : Oct 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Baicalein : CK(370) : AC(242)
Diseases : Cervical Cancer : CK(1024) : AC(627), Inflammation : CK(17054) : AC(5865)
Pharmacological Actions : Anti-Inflammatory Agents : CK(42985) : AC(17177), NF-kappaB Inhibitor : CK(6453) : AC(3744), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(12567) : AC(5162)
Additional Keywords : Anti-Inflammatory Agents, Baicalein, Cervical Cancer, Gene Expression Regulation : CK(1435) : AC(630), NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Carnosic acid attenuates RANKL-induced oxidative stress and osteoclastogenesis.

Article Published Date : Sep 30, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Carnosic Acid : CK(167) : AC(112)
Diseases : Bone Diseases : CK(345) : AC(112)
Pharmacological Actions : Anti-Inflammatory Agents : CK(42985) : AC(17177), Antioxidants : CK(36960) : AC(15513), NF-kappaB Inhibitor : CK(6453) : AC(3744), Osteoprotective : CK(2226) : AC(749)
Additional Keywords : Anti-Inflammatory Agents, Antioxidants : CK(303) : AC(126), Bone Diseases, Carnosic Acid, NF-kappaB Inhibitor, Osteoprotective

Moracin M inhibited airway inflammation in vitro and in vivo, and it has therapeutic potential for treating lung inflammatory disorders.

Article Published Date : Jul 14, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : White Mulberry : CK(156) : AC(66)
Diseases : Experimental Lung Inflammation : CK(25) : AC(7), Inflammation : CK(17054) : AC(5865)
Pharmacological Actions : Anti-Inflammatory Agents : CK(42985) : AC(17177), NF-kappaB Inhibitor : CK(6453) : AC(3744)
Additional Keywords : Anti-Inflammatory Agents, Experimental Lung Inflammation, Inflammation : CK(128) : AC(57), NF-kappaB Inhibitor, White Mulberry

Oligonol has protective activity against oxidative stress-induced inflammation.

Article Published Date : Mar 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Lychee : CK(90) : AC(52)
Diseases : Inflammation : CK(17054) : AC(5865), Oxidative Stress : CK(16183) : AC(6369)
Pharmacological Actions : Anti-Inflammatory Agents : CK(42985) : AC(17177), Antioxidants : CK(36960) : AC(15513), Cyclooxygenase Inhibitors : CK(86) : AC(45), NF-kappaB Inhibitor : CK(6453) : AC(3744)
Additional Keywords : Anti-Inflammatory Agents, Antioxidants : CK(303) : AC(126), Cyclooxygenase Inhibitors, Inflammation : CK(128) : AC(57), Lychee, NF-kappaB Inhibitor, oxidative stress

Phloretin inhibits phorbol ester-induced tumor promotion and expression of cyclooxygenase-2 in mouse skin.

Article Published Date : Feb 29, 2012
Study Type : Animal Study
Additional Links
Substances : Phloretin : CK(275) : AC(165)
Diseases : Skin Cancer : CK(1881) : AC(876)
Pharmacological Actions : Anticarcinogenic Agents : CK(2161) : AC(1024), Cyclooxygenase 2 Inhibitors : CK(2357) : AC(1386), NF-kappaB Inhibitor : CK(6453) : AC(3744)
Additional Keywords : Anticarcinogenic Agents, Cyclooxygenase 2 Inhibitors, NF-kappaB Inhibitor, Phloretin, skin cancer

Piceatannol provides remarkable renoprotection in diabetes by abrogating oxidative stress and NF-kB activation.

Article Published Date : Nov 25, 2016
Study Type : Animal Study
Additional Links
Substances : Piceatannol : CK(189) : AC(126)
Diseases : Diabetic Nephropathy : CK(1535) : AC(580)
Pharmacological Actions : Anti-Inflammatory Agents : CK(42985) : AC(17177), Antioxidants : CK(36960) : AC(15513), NF-kappaB Inhibitor : CK(6453) : AC(3744), Renoprotective : CK(4870) : AC(2117)
Additional Keywords : Anti-Inflammatory Agents, Antioxidants : CK(303) : AC(126), Diabetic Nephropathy, NF-kappaB Inhibitor, Piceatannol, Renoprotective

Pomegranate fruit extract significantly inhibits lung tumorigenesis in A/J mice.

Article Published Date : Mar 31, 2007
Study Type : Animal Study
Additional Links
Substances : Pomegranate : CK(1828) : AC(580)
Diseases : Benzo[a]pyrene-induced Toxicity : CK(217) : AC(131), Lung Cancer : CK(3206) : AC(1514)
Pharmacological Actions : Anticarcinogenic Agents : CK(2161) : AC(1024), Chemopreventive : CK(6666) : AC(2213), NF-kappaB Inhibitor : CK(6453) : AC(3744)
Additional Keywords : Anticarcinogenic Agents, Chemopreventive, lung cancer, NF-kappaB Inhibitor, Phytotherapy : CK(4085) : AC(1068), Plant Extracts : CK(19519) : AC(7134), pomegranate
Problem Substances : Benzo(a)pyrene : CK(186) : AC(110)

This report confirms the anti-inflammatory potential of this traditionally employed herbal medicine in vitro.

Article Published Date : Dec 31, 2011
Study Type : In Vitro Study
Additional Links
Substances : Justicia gendarussa : CK(10) : AC(8)
Diseases : Inflammation : CK(17054) : AC(5865), Lipopolysaccharide-Induced Toxicity : CK(3477) : AC(2023)
Pharmacological Actions : 5-Lipoxygenase Inhibitor : CK(49) : AC(32), Anti-Inflammatory Agents : CK(42985) : AC(17177), Cyclooxygenase 2 Inhibitors : CK(2357) : AC(1386), Interleukin-6 Downregulation : CK(10078) : AC(3912), NF-kappaB Inhibitor : CK(6453) : AC(3744)
Additional Keywords : 5-Lipoxygenase Inhibitor, Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Inflammation : CK(128) : AC(57), Interleukin-6 Downregulation, Justicia gendarussa, Lipopolysaccharide-Induced Toxicity, NF-kappaB Inhibitor, Plant Extracts : CK(19519) : AC(7134)

Vitamin K2 may be a potential therapeutic agent in the treatment of prostate cancer.

Article Published Date : Dec 31, 2012
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Vitamin K2 : CK(560) : AC(91)
Diseases : Prostate Cancer : CK(2893) : AC(1088)
Pharmacological Actions : Angiogenesis Inhibitors : CK(758) : AC(506), Anti-Inflammatory Agents : CK(42985) : AC(17177), Anti-metastatic : CK(3046) : AC(2316), Apoptotic : CK(10232) : AC(7920), NF-kappaB Inhibitor : CK(6453) : AC(3744)
Additional Keywords : Angiogenesis Inhibitors, Anti-Inflammatory Agents, Anti-metastatic, Apoptotic, NF-kappaB Inhibitor, prostate cancer, Vitamin K2 : CK(16) : AC(6)

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