Results for NF-kappaB Inhibitor

Allicin provides protection against arsenic trioxide induced liver injury.

Article Published Date : Feb 28, 2017
Study Type : Animal Study
Additional Links
Substances : Allicin : CK(48) : AC(25)
Diseases : Arsenic Poisoning : CK(160) : AC(49), Oxidative Stress : CK(6519) : AC(2436)
Pharmacological Actions : Antioxidants : CK(14410) : AC(5758), NF-kappaB Inhibitor : CK(2446) : AC(1436), Nrf2 activation : CK(177) : AC(86)
Additional Keywords : Allicin, Antioxidants : CK(1) : AC(1), Arsenic Poisoning, NF-kappaB Inhibitor, Nrf2 activation, oxidative stress
Problem Substances : Arsenic Trioxide : CK(6) : AC(4)

Arctigenin protects against ultraviolet-A-induced damage to stemness.

Article Published Date : Feb 24, 2018
Study Type : In Vitro Study
Additional Links
Substances : Arctigenin : CK(16) : AC(11)
Diseases : Ultraviolet Radiation Induced Damage : CK(100) : AC(44)
Pharmacological Actions : Anti-Inflammatory Agents : CK(12461) : AC(4729), NF-kappaB Inhibitor : CK(2446) : AC(1436), Photoprotective : CK(74) : AC(27)
Additional Keywords : Anti-Inflammatory Agents, Arctigenin, NF-kappaB Inhibitor, Photoprotective, Ultraviolet Radiation Induced Damage

Baicalein could be a lead compound for the modulation of inflammatory diseases as well as certain cancers.

Article Published Date : Oct 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Baicalein : CK(106) : AC(75)
Diseases : Cervical Cancer : CK(594) : AC(288), Inflammation : CK(6531) : AC(1986)
Pharmacological Actions : Anti-Inflammatory Agents : CK(12461) : AC(4729), NF-kappaB Inhibitor : CK(2446) : AC(1436), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(4357) : AC(1763)
Additional Keywords : Anti-Inflammatory Agents, Baicalein, Cervical Cancer, Gene Expression Regulation : CK(431) : AC(214), NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Carnosic acid attenuates RANKL-induced oxidative stress and osteoclastogenesis.

Article Published Date : Sep 30, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Carnosic Acid : CK(39) : AC(27)
Diseases : Bone Diseases : CK(18) : AC(6)
Pharmacological Actions : Anti-Inflammatory Agents : CK(12461) : AC(4729), Antioxidants : CK(14410) : AC(5758), NF-kappaB Inhibitor : CK(2446) : AC(1436), Osteoprotective : CK(20) : AC(6)
Additional Keywords : Anti-Inflammatory Agents, Antioxidants : CK(1) : AC(1), Bone Diseases, Carnosic Acid, NF-kappaB Inhibitor, Osteoprotective

Moracin M inhibited airway inflammation in vitro and in vivo, and it has therapeutic potential for treating lung inflammatory disorders.

Article Published Date : Jul 14, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : White Mulberry : CK(94) : AC(34)
Diseases : Experimental Lung Inflammation : CK(10) : AC(1), Inflammation : CK(6531) : AC(1986)
Pharmacological Actions : Anti-Inflammatory Agents : CK(12461) : AC(4729), NF-kappaB Inhibitor : CK(2446) : AC(1436)
Additional Keywords : Anti-Inflammatory Agents, Experimental Lung Inflammation, Inflammation : CK(2) : AC(2), NF-kappaB Inhibitor, White Mulberry

Oligonol has protective activity against oxidative stress-induced inflammation.

Article Published Date : Mar 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Lychee : CK(56) : AC(29)
Diseases : Inflammation : CK(6531) : AC(1986), Oxidative Stress : CK(6519) : AC(2436)
Pharmacological Actions : Anti-Inflammatory Agents : CK(12461) : AC(4729), Antioxidants : CK(14410) : AC(5758), Cyclooxygenase Inhibitors : CK(71) : AC(39), NF-kappaB Inhibitor : CK(2446) : AC(1436)
Additional Keywords : Anti-Inflammatory Agents, Antioxidants : CK(1) : AC(1), Cyclooxygenase Inhibitors, Inflammation : CK(2) : AC(2), Lychee, NF-kappaB Inhibitor, oxidative stress

Phloretin inhibits phorbol ester-induced tumor promotion and expression of cyclooxygenase-2 in mouse skin.

Article Published Date : Feb 29, 2012
Study Type : Animal Study
Additional Links
Substances : Phloretin : CK(96) : AC(46)
Diseases : Skin Cancer : CK(1175) : AC(495)
Pharmacological Actions : Anticarcinogenic Agents : CK(1577) : AC(756), Cyclooxygenase 2 Inhibitors : CK(1114) : AC(645), NF-kappaB Inhibitor : CK(2446) : AC(1436)
Additional Keywords : Anticarcinogenic Agents, Cyclooxygenase 2 Inhibitors, NF-kappaB Inhibitor, Phloretin, skin cancer

Piceatannol provides remarkable renoprotection in diabetes by abrogating oxidative stress and NF-kB activation.

Article Published Date : Nov 25, 2016
Study Type : Animal Study
Additional Links
Substances : Piceatannol : CK(23) : AC(16)
Diseases : Diabetic Nephropathy : CK(394) : AC(151)
Pharmacological Actions : Anti-Inflammatory Agents : CK(12461) : AC(4729), Antioxidants : CK(14410) : AC(5758), NF-kappaB Inhibitor : CK(2446) : AC(1436), Renoprotective : CK(1308) : AC(593)
Additional Keywords : Anti-Inflammatory Agents, Antioxidants : CK(1) : AC(1), Diabetic Nephropathy, NF-kappaB Inhibitor, Piceatannol, Renoprotective

Pomegranate fruit extract significantly inhibits lung tumorigenesis in A/J mice.

Article Published Date : Mar 31, 2007
Study Type : Animal Study
Additional Links
Substances : Pomegranate : CK(968) : AC(315)
Diseases : Benzo[a]pyrene-induced Toxicity : CK(65) : AC(36), Lung Cancer : CK(1741) : AC(742)
Pharmacological Actions : Anticarcinogenic Agents : CK(1577) : AC(756), Chemopreventive : CK(4220) : AC(1326), NF-kappaB Inhibitor : CK(2446) : AC(1436)
Additional Keywords : Anticarcinogenic Agents, Chemopreventive, lung cancer, NF-kappaB Inhibitor, Phytotherapy : CK(2309) : AC(597), Plant Extracts : CK(11762) : AC(4236), pomegranate
Problem Substances : Benzo(a)pyrene : CK(19) : AC(10)

This report confirms the anti-inflammatory potential of this traditionally employed herbal medicine in vitro.

Article Published Date : Dec 31, 2011
Study Type : In Vitro Study
Additional Links
Substances : Justicia gendarussa : CK(1) : AC(1)
Diseases : Inflammation : CK(6531) : AC(1986), Lipopolysaccharide-Induced Toxicity : CK(1105) : AC(650)
Pharmacological Actions : 5-Lipoxygenase Inhibitor : CK(8) : AC(7), Anti-Inflammatory Agents : CK(12461) : AC(4729), Cyclooxygenase 2 Inhibitors : CK(1114) : AC(645), Interleukin-6 Downregulation : CK(3054) : AC(1144), NF-kappaB Inhibitor : CK(2446) : AC(1436)
Additional Keywords : 5-Lipoxygenase Inhibitor, Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Inflammation : CK(2) : AC(2), Interleukin-6 Downregulation, Justicia gendarussa, Lipopolysaccharide-Induced Toxicity, NF-kappaB Inhibitor, Plant Extracts : CK(11762) : AC(4236)

Vitamin K2 may be a potential therapeutic agent in the treatment of prostate cancer.

Article Published Date : Dec 31, 2012
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Vitamin K2 : CK(383) : AC(50)
Diseases : Prostate Cancer : CK(2097) : AC(687)
Pharmacological Actions : Angiogenesis Inhibitors : CK(114) : AC(62), Anti-Inflammatory Agents : CK(12461) : AC(4729), Anti-metastatic : CK(1284) : AC(927), Apoptotic : CK(5217) : AC(3846), NF-kappaB Inhibitor : CK(2446) : AC(1436)
Additional Keywords : Angiogenesis Inhibitors, Anti-Inflammatory Agents, Anti-metastatic, Apoptotic, NF-kappaB Inhibitor, prostate cancer, Vitamin K2 : CK(1) : AC(1)

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