Results for NF-kappaB Inhibitor

Allicin provides protection against arsenic trioxide induced liver injury.

Article Published Date : Feb 28, 2017
Study Type : Animal Study
Additional Links
Substances : Allicin : CK(360) : AC(196)
Diseases : Arsenic Poisoning : CK(364) : AC(125), Oxidative Stress : CK(13443) : AC(5362)
Pharmacological Actions : Antioxidants : CK(32218) : AC(13966), NF-kappaB Inhibitor : CK(5541) : AC(3333), Nrf2 activation : CK(2908) : AC(1749)
Additional Keywords : Allicin, Antioxidants : CK(303) : AC(126), Arsenic Poisoning, NF-kappaB Inhibitor, Nrf2 activation, oxidative stress
Problem Substances : Arsenic Trioxide : CK(43) : AC(26)

Arctigenin protects against ultraviolet-A-induced damage to stemness.

Article Published Date : Feb 24, 2018
Study Type : In Vitro Study
Additional Links
Substances : Arctigenin : CK(151) : AC(107)
Diseases : Ultraviolet Radiation Induced Damage : CK(742) : AC(311)
Pharmacological Actions : Anti-Inflammatory Agents : CK(35225) : AC(14960), NF-kappaB Inhibitor : CK(5541) : AC(3333), Photoprotective : CK(743) : AC(288)
Additional Keywords : Anti-Inflammatory Agents, Arctigenin, NF-kappaB Inhibitor, Photoprotective, Ultraviolet Radiation Induced Damage

Baicalein could be a lead compound for the modulation of inflammatory diseases as well as certain cancers.

Article Published Date : Oct 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Baicalein : CK(276) : AC(177)
Diseases : Cervical Cancer : CK(954) : AC(577), Inflammation : CK(15193) : AC(5122)
Pharmacological Actions : Anti-Inflammatory Agents : CK(35225) : AC(14960), NF-kappaB Inhibitor : CK(5541) : AC(3333), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(10605) : AC(4591)
Additional Keywords : Anti-Inflammatory Agents, Baicalein, Cervical Cancer, Gene Expression Regulation : CK(1387) : AC(615), NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Carnosic acid attenuates RANKL-induced oxidative stress and osteoclastogenesis.

Article Published Date : Sep 30, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Carnosic Acid : CK(165) : AC(111)
Diseases : Bone Diseases : CK(309) : AC(96)
Pharmacological Actions : Anti-Inflammatory Agents : CK(35225) : AC(14960), Antioxidants : CK(32218) : AC(13966), NF-kappaB Inhibitor : CK(5541) : AC(3333), Osteoprotective : CK(1865) : AC(666)
Additional Keywords : Anti-Inflammatory Agents, Antioxidants : CK(303) : AC(126), Bone Diseases, Carnosic Acid, NF-kappaB Inhibitor, Osteoprotective

Moracin M inhibited airway inflammation in vitro and in vivo, and it has therapeutic potential for treating lung inflammatory disorders.

Article Published Date : Jul 14, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : White Mulberry : CK(156) : AC(66)
Diseases : Experimental Lung Inflammation : CK(25) : AC(7), Inflammation : CK(15193) : AC(5122)
Pharmacological Actions : Anti-Inflammatory Agents : CK(35225) : AC(14960), NF-kappaB Inhibitor : CK(5541) : AC(3333)
Additional Keywords : Anti-Inflammatory Agents, Experimental Lung Inflammation, Inflammation : CK(128) : AC(57), NF-kappaB Inhibitor, White Mulberry

Oligonol has protective activity against oxidative stress-induced inflammation.

Article Published Date : Mar 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Lychee : CK(90) : AC(52)
Diseases : Inflammation : CK(15193) : AC(5122), Oxidative Stress : CK(13443) : AC(5362)
Pharmacological Actions : Anti-Inflammatory Agents : CK(35225) : AC(14960), Antioxidants : CK(32218) : AC(13966), Cyclooxygenase Inhibitors : CK(86) : AC(45), NF-kappaB Inhibitor : CK(5541) : AC(3333)
Additional Keywords : Anti-Inflammatory Agents, Antioxidants : CK(303) : AC(126), Cyclooxygenase Inhibitors, Inflammation : CK(128) : AC(57), Lychee, NF-kappaB Inhibitor, oxidative stress

Phloretin inhibits phorbol ester-induced tumor promotion and expression of cyclooxygenase-2 in mouse skin.

Article Published Date : Feb 29, 2012
Study Type : Animal Study
Additional Links
Substances : Phloretin : CK(232) : AC(137)
Diseases : Skin Cancer : CK(1664) : AC(806)
Pharmacological Actions : Anticarcinogenic Agents : CK(2126) : AC(1010), Cyclooxygenase 2 Inhibitors : CK(2067) : AC(1256), NF-kappaB Inhibitor : CK(5541) : AC(3333)
Additional Keywords : Anticarcinogenic Agents, Cyclooxygenase 2 Inhibitors, NF-kappaB Inhibitor, Phloretin, skin cancer

Piceatannol provides remarkable renoprotection in diabetes by abrogating oxidative stress and NF-kB activation.

Article Published Date : Nov 25, 2016
Study Type : Animal Study
Additional Links
Substances : Piceatannol : CK(187) : AC(124)
Diseases : Diabetic Nephropathy : CK(1356) : AC(518)
Pharmacological Actions : Anti-Inflammatory Agents : CK(35225) : AC(14960), Antioxidants : CK(32218) : AC(13966), NF-kappaB Inhibitor : CK(5541) : AC(3333), Renoprotective : CK(4133) : AC(1900)
Additional Keywords : Anti-Inflammatory Agents, Antioxidants : CK(303) : AC(126), Diabetic Nephropathy, NF-kappaB Inhibitor, Piceatannol, Renoprotective

Pomegranate fruit extract significantly inhibits lung tumorigenesis in A/J mice.

Article Published Date : Mar 31, 2007
Study Type : Animal Study
Additional Links
Substances : Pomegranate : CK(1762) : AC(565)
Diseases : Benzo[a]pyrene-induced Toxicity : CK(202) : AC(122), Lung Cancer : CK(2971) : AC(1387)
Pharmacological Actions : Anticarcinogenic Agents : CK(2126) : AC(1010), Chemopreventive : CK(6381) : AC(2130), NF-kappaB Inhibitor : CK(5541) : AC(3333)
Additional Keywords : Anticarcinogenic Agents, Chemopreventive, lung cancer, NF-kappaB Inhibitor, Phytotherapy : CK(3908) : AC(1013), Plant Extracts : CK(18030) : AC(6690), pomegranate
Problem Substances : Benzo(a)pyrene : CK(174) : AC(104)

This report confirms the anti-inflammatory potential of this traditionally employed herbal medicine in vitro.

Article Published Date : Dec 31, 2011
Study Type : In Vitro Study
Additional Links
Substances : Justicia gendarussa : CK(10) : AC(8)
Diseases : Inflammation : CK(15193) : AC(5122), Lipopolysaccharide-Induced Toxicity : CK(2918) : AC(1800)
Pharmacological Actions : 5-Lipoxygenase Inhibitor : CK(47) : AC(30), Anti-Inflammatory Agents : CK(35225) : AC(14960), Cyclooxygenase 2 Inhibitors : CK(2067) : AC(1256), Interleukin-6 Downregulation : CK(8987) : AC(3465), NF-kappaB Inhibitor : CK(5541) : AC(3333)
Additional Keywords : 5-Lipoxygenase Inhibitor, Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Inflammation : CK(128) : AC(57), Interleukin-6 Downregulation, Justicia gendarussa, Lipopolysaccharide-Induced Toxicity, NF-kappaB Inhibitor, Plant Extracts : CK(18030) : AC(6690)

Vitamin K2 may be a potential therapeutic agent in the treatment of prostate cancer.

Article Published Date : Dec 31, 2012
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Vitamin K2 : CK(560) : AC(91)
Diseases : Prostate Cancer : CK(2762) : AC(1026)
Pharmacological Actions : Angiogenesis Inhibitors : CK(712) : AC(472), Anti-Inflammatory Agents : CK(35225) : AC(14960), Anti-metastatic : CK(2811) : AC(2130), Apoptotic : CK(9052) : AC(7189), NF-kappaB Inhibitor : CK(5541) : AC(3333)
Additional Keywords : Angiogenesis Inhibitors, Anti-Inflammatory Agents, Anti-metastatic, Apoptotic, NF-kappaB Inhibitor, prostate cancer, Vitamin K2 : CK(16) : AC(6)

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