Results for NF-kappaB Inhibitor

Allicin provides protection against arsenic trioxide induced liver injury.

Article Published Date : Feb 28, 2017
Study Type : Animal Study
Additional Links
Substances : Allicin : CK(361) : AC(197)
Diseases : Arsenic Poisoning : CK(383) : AC(129), Oxidative Stress : CK(14883) : AC(5770)
Pharmacological Actions : Antioxidants : CK(34731) : AC(14567), NF-kappaB Inhibitor : CK(5977) : AC(3479), Nrf2 activation : CK(3163) : AC(1798)
Additional Keywords : Allicin, Antioxidants : CK(303) : AC(126), Arsenic Poisoning, NF-kappaB Inhibitor, Nrf2 activation, oxidative stress
Problem Substances : Arsenic Trioxide : CK(45) : AC(27)

Arctigenin protects against ultraviolet-A-induced damage to stemness.

Article Published Date : Feb 24, 2018
Study Type : In Vitro Study
Additional Links
Substances : Arctigenin : CK(160) : AC(107)
Diseases : Ultraviolet Radiation Induced Damage : CK(790) : AC(333)
Pharmacological Actions : Anti-Inflammatory Agents : CK(39913) : AC(15933), NF-kappaB Inhibitor : CK(5977) : AC(3479), Photoprotective : CK(780) : AC(305)
Additional Keywords : Anti-Inflammatory Agents, Arctigenin, NF-kappaB Inhibitor, Photoprotective, Ultraviolet Radiation Induced Damage

Baicalein could be a lead compound for the modulation of inflammatory diseases as well as certain cancers.

Article Published Date : Oct 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Baicalein : CK(312) : AC(202)
Diseases : Cervical Cancer : CK(983) : AC(602), Inflammation : CK(16154) : AC(5522)
Pharmacological Actions : Anti-Inflammatory Agents : CK(39913) : AC(15933), NF-kappaB Inhibitor : CK(5977) : AC(3479), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(11743) : AC(4824)
Additional Keywords : Anti-Inflammatory Agents, Baicalein, Cervical Cancer, Gene Expression Regulation : CK(1412) : AC(625), NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Carnosic acid attenuates RANKL-induced oxidative stress and osteoclastogenesis.

Article Published Date : Sep 30, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Carnosic Acid : CK(167) : AC(112)
Diseases : Bone Diseases : CK(335) : AC(106)
Pharmacological Actions : Anti-Inflammatory Agents : CK(39913) : AC(15933), Antioxidants : CK(34731) : AC(14567), NF-kappaB Inhibitor : CK(5977) : AC(3479), Osteoprotective : CK(2057) : AC(692)
Additional Keywords : Anti-Inflammatory Agents, Antioxidants : CK(303) : AC(126), Bone Diseases, Carnosic Acid, NF-kappaB Inhibitor, Osteoprotective

Moracin M inhibited airway inflammation in vitro and in vivo, and it has therapeutic potential for treating lung inflammatory disorders.

Article Published Date : Jul 14, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : White Mulberry : CK(156) : AC(66)
Diseases : Experimental Lung Inflammation : CK(25) : AC(7), Inflammation : CK(16154) : AC(5522)
Pharmacological Actions : Anti-Inflammatory Agents : CK(39913) : AC(15933), NF-kappaB Inhibitor : CK(5977) : AC(3479)
Additional Keywords : Anti-Inflammatory Agents, Experimental Lung Inflammation, Inflammation : CK(128) : AC(57), NF-kappaB Inhibitor, White Mulberry

Oligonol has protective activity against oxidative stress-induced inflammation.

Article Published Date : Mar 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Lychee : CK(90) : AC(52)
Diseases : Inflammation : CK(16154) : AC(5522), Oxidative Stress : CK(14883) : AC(5770)
Pharmacological Actions : Anti-Inflammatory Agents : CK(39913) : AC(15933), Antioxidants : CK(34731) : AC(14567), Cyclooxygenase Inhibitors : CK(86) : AC(45), NF-kappaB Inhibitor : CK(5977) : AC(3479)
Additional Keywords : Anti-Inflammatory Agents, Antioxidants : CK(303) : AC(126), Cyclooxygenase Inhibitors, Inflammation : CK(128) : AC(57), Lychee, NF-kappaB Inhibitor, oxidative stress

Phloretin inhibits phorbol ester-induced tumor promotion and expression of cyclooxygenase-2 in mouse skin.

Article Published Date : Feb 29, 2012
Study Type : Animal Study
Additional Links
Substances : Phloretin : CK(232) : AC(137)
Diseases : Skin Cancer : CK(1808) : AC(838)
Pharmacological Actions : Anticarcinogenic Agents : CK(2152) : AC(1018), Cyclooxygenase 2 Inhibitors : CK(2268) : AC(1330), NF-kappaB Inhibitor : CK(5977) : AC(3479)
Additional Keywords : Anticarcinogenic Agents, Cyclooxygenase 2 Inhibitors, NF-kappaB Inhibitor, Phloretin, skin cancer

Piceatannol provides remarkable renoprotection in diabetes by abrogating oxidative stress and NF-kB activation.

Article Published Date : Nov 25, 2016
Study Type : Animal Study
Additional Links
Substances : Piceatannol : CK(188) : AC(125)
Diseases : Diabetic Nephropathy : CK(1407) : AC(541)
Pharmacological Actions : Anti-Inflammatory Agents : CK(39913) : AC(15933), Antioxidants : CK(34731) : AC(14567), NF-kappaB Inhibitor : CK(5977) : AC(3479), Renoprotective : CK(4566) : AC(1978)
Additional Keywords : Anti-Inflammatory Agents, Antioxidants : CK(303) : AC(126), Diabetic Nephropathy, NF-kappaB Inhibitor, Piceatannol, Renoprotective

Pomegranate fruit extract significantly inhibits lung tumorigenesis in A/J mice.

Article Published Date : Mar 31, 2007
Study Type : Animal Study
Additional Links
Substances : Pomegranate : CK(1800) : AC(573)
Diseases : Benzo[a]pyrene-induced Toxicity : CK(216) : AC(130), Lung Cancer : CK(3068) : AC(1434)
Pharmacological Actions : Anticarcinogenic Agents : CK(2152) : AC(1018), Chemopreventive : CK(6613) : AC(2176), NF-kappaB Inhibitor : CK(5977) : AC(3479)
Additional Keywords : Anticarcinogenic Agents, Chemopreventive, lung cancer, NF-kappaB Inhibitor, Phytotherapy : CK(4004) : AC(1032), Plant Extracts : CK(18767) : AC(6786), pomegranate
Problem Substances : Benzo(a)pyrene : CK(185) : AC(109)

This report confirms the anti-inflammatory potential of this traditionally employed herbal medicine in vitro.

Article Published Date : Dec 31, 2011
Study Type : In Vitro Study
Additional Links
Substances : Justicia gendarussa : CK(10) : AC(8)
Diseases : Inflammation : CK(16154) : AC(5522), Lipopolysaccharide-Induced Toxicity : CK(3245) : AC(1884)
Pharmacological Actions : 5-Lipoxygenase Inhibitor : CK(48) : AC(31), Anti-Inflammatory Agents : CK(39913) : AC(15933), Cyclooxygenase 2 Inhibitors : CK(2268) : AC(1330), Interleukin-6 Downregulation : CK(9389) : AC(3627), NF-kappaB Inhibitor : CK(5977) : AC(3479)
Additional Keywords : 5-Lipoxygenase Inhibitor, Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Inflammation : CK(128) : AC(57), Interleukin-6 Downregulation, Justicia gendarussa, Lipopolysaccharide-Induced Toxicity, NF-kappaB Inhibitor, Plant Extracts : CK(18767) : AC(6786)

Vitamin K2 may be a potential therapeutic agent in the treatment of prostate cancer.

Article Published Date : Dec 31, 2012
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Vitamin K2 : CK(560) : AC(91)
Diseases : Prostate Cancer : CK(2810) : AC(1051)
Pharmacological Actions : Angiogenesis Inhibitors : CK(725) : AC(482), Anti-Inflammatory Agents : CK(39913) : AC(15933), Anti-metastatic : CK(2882) : AC(2191), Apoptotic : CK(9631) : AC(7414), NF-kappaB Inhibitor : CK(5977) : AC(3479)
Additional Keywords : Angiogenesis Inhibitors, Anti-Inflammatory Agents, Anti-metastatic, Apoptotic, NF-kappaB Inhibitor, prostate cancer, Vitamin K2 : CK(16) : AC(6)

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