Results for NF-kappaB Inhibitor

Allicin provides protection against arsenic trioxide induced liver injury.

Article Published Date : Feb 28, 2017
Study Type : Animal Study
Additional Links
Substances : Allicin : CK(361) : AC(197)
Diseases : Arsenic Poisoning : CK(409) : AC(134), Oxidative Stress : CK(15747) : AC(6111)
Pharmacological Actions : Antioxidants : CK(36083) : AC(15124), NF-kappaB Inhibitor : CK(6153) : AC(3582), Nrf2 activation : CK(3288) : AC(1877)
Additional Keywords : Allicin, Antioxidants : CK(303) : AC(126), Arsenic Poisoning, NF-kappaB Inhibitor, Nrf2 activation, oxidative stress
Problem Substances : Arsenic Trioxide : CK(45) : AC(27)

Arctigenin protects against ultraviolet-A-induced damage to stemness.

Article Published Date : Feb 24, 2018
Study Type : In Vitro Study
Additional Links
Substances : Arctigenin : CK(180) : AC(118)
Diseases : Ultraviolet Radiation Induced Damage : CK(806) : AC(344)
Pharmacological Actions : Anti-Inflammatory Agents : CK(41633) : AC(16627), NF-kappaB Inhibitor : CK(6153) : AC(3582), Photoprotective : CK(795) : AC(313)
Additional Keywords : Anti-Inflammatory Agents, Arctigenin, NF-kappaB Inhibitor, Photoprotective, Ultraviolet Radiation Induced Damage

Baicalein could be a lead compound for the modulation of inflammatory diseases as well as certain cancers.

Article Published Date : Oct 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Baicalein : CK(313) : AC(203)
Diseases : Cervical Cancer : CK(998) : AC(608), Inflammation : CK(16745) : AC(5712)
Pharmacological Actions : Anti-Inflammatory Agents : CK(41633) : AC(16627), NF-kappaB Inhibitor : CK(6153) : AC(3582), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(12156) : AC(4999)
Additional Keywords : Anti-Inflammatory Agents, Baicalein, Cervical Cancer, Gene Expression Regulation : CK(1433) : AC(628), NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Carnosic acid attenuates RANKL-induced oxidative stress and osteoclastogenesis.

Article Published Date : Sep 30, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Carnosic Acid : CK(167) : AC(112)
Diseases : Bone Diseases : CK(341) : AC(110)
Pharmacological Actions : Anti-Inflammatory Agents : CK(41633) : AC(16627), Antioxidants : CK(36083) : AC(15124), NF-kappaB Inhibitor : CK(6153) : AC(3582), Osteoprotective : CK(2149) : AC(731)
Additional Keywords : Anti-Inflammatory Agents, Antioxidants : CK(303) : AC(126), Bone Diseases, Carnosic Acid, NF-kappaB Inhibitor, Osteoprotective

Moracin M inhibited airway inflammation in vitro and in vivo, and it has therapeutic potential for treating lung inflammatory disorders.

Article Published Date : Jul 14, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : White Mulberry : CK(156) : AC(66)
Diseases : Experimental Lung Inflammation : CK(25) : AC(7), Inflammation : CK(16745) : AC(5712)
Pharmacological Actions : Anti-Inflammatory Agents : CK(41633) : AC(16627), NF-kappaB Inhibitor : CK(6153) : AC(3582)
Additional Keywords : Anti-Inflammatory Agents, Experimental Lung Inflammation, Inflammation : CK(128) : AC(57), NF-kappaB Inhibitor, White Mulberry

Oligonol has protective activity against oxidative stress-induced inflammation.

Article Published Date : Mar 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Lychee : CK(90) : AC(52)
Diseases : Inflammation : CK(16745) : AC(5712), Oxidative Stress : CK(15747) : AC(6111)
Pharmacological Actions : Anti-Inflammatory Agents : CK(41633) : AC(16627), Antioxidants : CK(36083) : AC(15124), Cyclooxygenase Inhibitors : CK(86) : AC(45), NF-kappaB Inhibitor : CK(6153) : AC(3582)
Additional Keywords : Anti-Inflammatory Agents, Antioxidants : CK(303) : AC(126), Cyclooxygenase Inhibitors, Inflammation : CK(128) : AC(57), Lychee, NF-kappaB Inhibitor, oxidative stress

Phloretin inhibits phorbol ester-induced tumor promotion and expression of cyclooxygenase-2 in mouse skin.

Article Published Date : Feb 29, 2012
Study Type : Animal Study
Additional Links
Substances : Phloretin : CK(232) : AC(137)
Diseases : Skin Cancer : CK(1850) : AC(851)
Pharmacological Actions : Anticarcinogenic Agents : CK(2153) : AC(1019), Cyclooxygenase 2 Inhibitors : CK(2309) : AC(1355), NF-kappaB Inhibitor : CK(6153) : AC(3582)
Additional Keywords : Anticarcinogenic Agents, Cyclooxygenase 2 Inhibitors, NF-kappaB Inhibitor, Phloretin, skin cancer

Piceatannol provides remarkable renoprotection in diabetes by abrogating oxidative stress and NF-kB activation.

Article Published Date : Nov 25, 2016
Study Type : Animal Study
Additional Links
Substances : Piceatannol : CK(189) : AC(126)
Diseases : Diabetic Nephropathy : CK(1489) : AC(560)
Pharmacological Actions : Anti-Inflammatory Agents : CK(41633) : AC(16627), Antioxidants : CK(36083) : AC(15124), NF-kappaB Inhibitor : CK(6153) : AC(3582), Renoprotective : CK(4738) : AC(2062)
Additional Keywords : Anti-Inflammatory Agents, Antioxidants : CK(303) : AC(126), Diabetic Nephropathy, NF-kappaB Inhibitor, Piceatannol, Renoprotective

Pomegranate fruit extract significantly inhibits lung tumorigenesis in A/J mice.

Article Published Date : Mar 31, 2007
Study Type : Animal Study
Additional Links
Substances : Pomegranate : CK(1827) : AC(579)
Diseases : Benzo[a]pyrene-induced Toxicity : CK(217) : AC(131), Lung Cancer : CK(3135) : AC(1463)
Pharmacological Actions : Anticarcinogenic Agents : CK(2153) : AC(1019), Chemopreventive : CK(6642) : AC(2196), NF-kappaB Inhibitor : CK(6153) : AC(3582)
Additional Keywords : Anticarcinogenic Agents, Chemopreventive, lung cancer, NF-kappaB Inhibitor, Phytotherapy : CK(4028) : AC(1048), Plant Extracts : CK(19049) : AC(6981), pomegranate
Problem Substances : Benzo(a)pyrene : CK(186) : AC(110)

This report confirms the anti-inflammatory potential of this traditionally employed herbal medicine in vitro.

Article Published Date : Dec 31, 2011
Study Type : In Vitro Study
Additional Links
Substances : Justicia gendarussa : CK(10) : AC(8)
Diseases : Inflammation : CK(16745) : AC(5712), Lipopolysaccharide-Induced Toxicity : CK(3344) : AC(1946)
Pharmacological Actions : 5-Lipoxygenase Inhibitor : CK(49) : AC(32), Anti-Inflammatory Agents : CK(41633) : AC(16627), Cyclooxygenase 2 Inhibitors : CK(2309) : AC(1355), Interleukin-6 Downregulation : CK(9740) : AC(3781), NF-kappaB Inhibitor : CK(6153) : AC(3582)
Additional Keywords : 5-Lipoxygenase Inhibitor, Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Inflammation : CK(128) : AC(57), Interleukin-6 Downregulation, Justicia gendarussa, Lipopolysaccharide-Induced Toxicity, NF-kappaB Inhibitor, Plant Extracts : CK(19049) : AC(6981)

Vitamin K2 may be a potential therapeutic agent in the treatment of prostate cancer.

Article Published Date : Dec 31, 2012
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Vitamin K2 : CK(560) : AC(91)
Diseases : Prostate Cancer : CK(2861) : AC(1066)
Pharmacological Actions : Angiogenesis Inhibitors : CK(742) : AC(495), Anti-Inflammatory Agents : CK(41633) : AC(16627), Anti-metastatic : CK(2933) : AC(2236), Apoptotic : CK(9816) : AC(7580), NF-kappaB Inhibitor : CK(6153) : AC(3582)
Additional Keywords : Angiogenesis Inhibitors, Anti-Inflammatory Agents, Anti-metastatic, Apoptotic, NF-kappaB Inhibitor, prostate cancer, Vitamin K2 : CK(16) : AC(6)

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