Results for Transgenerational inheritance

Ancestral dichlorodiphenyltrichloroethane (DDT) exposure promotes epigenetic transgenerational inheritance of obesity.

Article Published Date : Oct 22, 2013
Study Type : Animal Study
Additional Links
Diseases : Fetal Origin of Adult Disease : CK(246) : AC(60), Obesity : CK(6879) : AC(1686), Prenatal Chemical Exposures : CK(1774) : AC(396)
Additional Keywords : Increased Risk : CK(6996) : AC(896), Transgenerational inheritance
Problem Substances : Dichloro-diphenyl-trichloroethane (DDT) : CK(208) : AC(35)

Ancestral folate promotes neuronal regeneration in serial generations of progeny.

Article Published Date : Jan 09, 2020
Study Type : Animal Study
Additional Links
Substances : Folate : CK(355) : AC(55)
Diseases : Folic Acid/Folate Deficiency : CK(230) : AC(35)
Pharmacological Actions : Regenerative : CK(408) : AC(172)
Additional Keywords : DNA Methylation : CK(329) : AC(70), Nerve Regeneration : CK(26) : AC(9), Transgenerational Epigenetic Modification : CK(229) : AC(89), Transgenerational inheritance

Ancestral plastics exposure induces transgenerational disease-specific sperm epigenome-wide association biomarkers.

Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(2930) : AC(882)
Additional Keywords : Risk Factors : CK(12084) : AC(1737), Transgenerational inheritance
Problem Substances : Bisphenol A : CK(3250) : AC(951)

Atrazine has the capacity to promote the epigenetic transgenerational inheritance of disease.

Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Diseases : Pesticide Toxicity : CK(1245) : AC(376)
Additional Keywords : Transgenerational Epigenetic Modification : CK(229) : AC(89), Transgenerational inheritance
Problem Substances : Pesticides : CK(2214) : AC(420)

Combinational exposure to Bisphenol A and a high-fat diet causes trans-generational Malfunction of the female reproductive system.

Article Published Date : Nov 12, 2021
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(2930) : AC(882), High Fat Diet : CK(1267) : AC(602), Infertility: Female : CK(541) : AC(127)
Additional Keywords : Risk Factors : CK(12084) : AC(1737), Transgenerational inheritance
Problem Substances : Bisphenol A : CK(3250) : AC(951)

Developmental exposure to lead induces transgenerational changes to zebrafish brain transcriptome.

Article Published Date : Dec 01, 2019
Study Type : Animal Study
Additional Links
Diseases : Prenatal Chemical Exposures : CK(1774) : AC(396)
Additional Keywords : Gene Expression : CK(270) : AC(101), Transgenerational inheritance
Problem Substances : Lead : CK(526) : AC(162)
Adverse Pharmacological Actions : Neurotoxic : CK(2424) : AC(562)

Dioxin induces epigenetic transgenerational inheritance of adult onset disease and sperm epimutations.

Article Published Date : Dec 31, 2011
Study Type : Animal Study
Additional Links
Diseases : Dioxin Toxicity : CK(27) : AC(11), Fetal Origin of Adult Disease : CK(246) : AC(60), Prenatal Chemical Exposures : CK(1774) : AC(396)
Additional Keywords : Risk Factors : CK(12084) : AC(1737), Transgenerational inheritance
Problem Substances : Dioxins : CK(28) : AC(9)

Epigenome-wide association study for glyphosate induced transgenerational sperm DNA methylation and histone retention epigenetic biomarkers for disease.

Article Published Date : Dec 08, 2020
Study Type : Animal Study
Additional Links
Diseases : Glyphosate Toxicity : CK(394) : AC(151)
Additional Keywords : Transgenerational Epigenetic Modification : CK(229) : AC(89), Transgenerational inheritance
Problem Substances : Glyphosate : CK(895) : AC(304)

Gestational low-dose BPA exposure impacts suprachiasmatic nucleus neurogenesis and circadian activity with transgenerational effects.

Article Published Date : Apr 30, 2021
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(2930) : AC(882)
Additional Keywords : Transgenerational inheritance
Problem Substances : Bisphenol A : CK(3250) : AC(951)

Hydrocarbons (jet fuel JP-8) induce epigenetic transgenerational inheritance of obesity, reproductive disease and sperm epimutations.

Article Published Date : Mar 31, 2013
Study Type : Animal Study
Additional Links
Diseases : Hair Loss : CK(293) : AC(69), Infertility: Male : CK(1286) : AC(320), Obesity : CK(6879) : AC(1686), Polycystic Ovary Syndrome : CK(1093) : AC(163)
Additional Keywords : DNA Methylation : CK(329) : AC(70), Increased Risk : CK(6996) : AC(896), Transgenerational inheritance
Problem Substances : Hydrocarbons : CK(48) : AC(0), Jet fuel : CK(6) : AC(0)

Maternal exposure to environmental bisphenol A impairs the neurons in hippocampus across generations.

Article Published Date : Feb 02, 2020
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(2930) : AC(882), Prenatal Chemical Exposures : CK(1774) : AC(396)
Additional Keywords : Transgenerational inheritance
Problem Substances : Bisphenol A : CK(3250) : AC(951)

Maternal vitamin B12 deficiency in rats alters DNA methylation in metabolically important genes in their offspring.

Article Published Date : Apr 30, 2020
Study Type : Animal Study
Additional Links
Diseases : Vitamin B 12 Deficiency : CK(656) : AC(91)
Additional Keywords : DNA Methylation : CK(329) : AC(70), Gene Expression : CK(270) : AC(101), Transgenerational inheritance

Mercury-induced epigenetic transgenerational inheritance of abnormal neurobehavior is correlated with sperm epimutations in zebrafish.

Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Diseases : Infertility: Male : CK(1286) : AC(320)
Additional Keywords : DNA Methylation : CK(329) : AC(70), Transgenerational inheritance
Problem Substances : Mercury : CK(808) : AC(185)

Multigenerational impacts of gestational bisphenol A exposure on the sperm function and fertility of male mice.

Article Published Date : Mar 31, 2021
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(2930) : AC(882), Infertility: Male : CK(1286) : AC(320), Prenatal Chemical Exposures : CK(1774) : AC(396)
Additional Keywords : Transgenerational inheritance
Problem Substances : Bisphenol A : CK(3250) : AC(951)

Paraquat exposure over generation affects lifespan and reproduction through mitochondrial disruption in C. elegans.

Article Published Date : Jan 14, 2021
Study Type : Animal Study
Additional Links
Diseases : Herbicide Toxicity : CK(12) : AC(7), Infertility : CK(2080) : AC(496)
Additional Keywords : Transgenerational inheritance
Problem Substances : Paraquat : CK(10) : AC(5)

Passing experiences on to future generations: endocrine disruptors and transgenerational inheritance of epimutations in brain and sperm.

Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Additional Keywords : Transgenerational inheritance
Problem Substances : Endocrine Disruptors : CK(1) : AC(1), Polychlorinated biphenyls (PCBs) : CK(320) : AC(50)

Paternal inheritance of bisphenol A cardiotoxic effects: The implications of sperm epigenome.

Article Published Date : Feb 19, 2021
Study Type : Animal Study
Additional Links
Substances : EGCG (Epigallocatechin gallate) : CK(1091) : AC(605)
Diseases : Bisphenol Toxicity : CK(2930) : AC(882), Fetal Origin of Adult Disease : CK(246) : AC(60)
Pharmacological Actions : Cytoprotective : CK(659) : AC(326)
Additional Keywords : Transgenerational inheritance
Problem Substances : Bisphenol A : CK(3250) : AC(951)
Adverse Pharmacological Actions : Cardiotoxic : CK(1000) : AC(164)

Prenatal exposure to a phthalate mixture leads to multigenerational and transgenerational effects on uterine morphology and function in mice.

Article Published Date : Feb 28, 2020
Study Type : Animal Study
Additional Links
Diseases : Phthalate Toxicity : CK(63) : AC(17), Prenatal Chemical Exposures : CK(1774) : AC(396)
Additional Keywords : Transgenerational inheritance
Problem Substances : Phthalates : CK(1031) : AC(187)

Preterm birth is associated with epigenetic programming of transgenerational hypertension in mice.

Article Published Date : Jan 23, 2020
Study Type : Animal Study
Additional Links
Diseases : Hypertension : CK(6384) : AC(950), Premature Birth : CK(558) : AC(61)
Additional Keywords : Risk Factors : CK(12084) : AC(1737), Transgenerational Epigenetic Modification : CK(229) : AC(89), Transgenerational inheritance

Small RNAs in the transgenerational inheritance of epigenetic information.

Article Published Date : Jan 13, 2020
Study Type : In Vitro Study
Additional Links
Additional Keywords : Epigenetic Modification : CK(417) : AC(164), Transgenerational inheritance

The data revealed that the endogenous opioid system may be altered in the offspring of morphine-treated parent.

Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Diseases : Prenatal Chemical Exposures : CK(1774) : AC(396)
Additional Keywords : Transgenerational inheritance
Problem Substances : Morphine : CK(20) : AC(0)

The effect of morphine might be transmitted to the next generation even after stop consuming morphine.

Article Published Date : Jan 16, 2020
Study Type : Animal Study
Additional Links
Diseases : Prenatal Chemical Exposures : CK(1774) : AC(396)
Additional Keywords : Transgenerational inheritance
Problem Substances : Morphine : CK(20) : AC(0)

The pesticide methoxychlor has the potential to promote the epigenetic transgenerational inheritance of disease.

Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Diseases : Obesity : CK(6879) : AC(1686), Pesticide Toxicity : CK(1245) : AC(376)
Additional Keywords : Increased Risk : CK(6996) : AC(896), Transgenerational Epigenetic Modification : CK(229) : AC(89), Transgenerational inheritance
Problem Substances : Methoxychlor : CK(1) : AC(0)

These results suggested that maternal exposure to BPA at enviromentally relavant concnetrations reduces reproductive function in Drosophila melanogaster females.

Article Published Date : Aug 31, 2021
Study Type : In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity : CK(2930) : AC(882)
Additional Keywords : Transgenerational inheritance
Problem Substances : Bisphenol A : CK(3250) : AC(951)

Transgenerational effects on intestinal inflammation status in mice perinatally exposed to bisphenol S.

Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(2930) : AC(882), Gastrointestinal Inflammation : CK(261) : AC(117), Prenatal Chemical Exposures : CK(1774) : AC(396)
Additional Keywords : Transgenerational inheritance
Problem Substances : Bisphenol S : CK(514) : AC(172)

Transgenerational impaired male fertility with an Igf2 epigenetic defect in the rat are induced by the endocrine disruptor p,p'-DDE.

Article Published Date : Oct 31, 2014
Study Type : Animal Study
Additional Links
Diseases : Infertility: Male : CK(1286) : AC(320), Sperm Quality: Low : CK(536) : AC(100)
Additional Keywords : Transgenerational inheritance
Problem Substances : Dichlorodiphenyldichloroethylene (DDE) : CK(12) : AC(0)

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