Results for Transgenerational inheritance

Ancestral dichlorodiphenyltrichloroethane (DDT) exposure promotes epigenetic transgenerational inheritance of obesity.

Article Published Date : Oct 22, 2013
Study Type : Animal Study
Additional Links
Diseases : Fetal Origin of Adult Disease : CK(103) : AC(23), Obesity : CK(4406) : AC(1073), Prenatal Chemical Exposures : CK(1220) : AC(265)
Additional Keywords : Increased Risk : CK(1600) : AC(192), Transgenerational inheritance
Problem Substances : Dichloro-diphenyl-trichloroethane (DDT) : CK(70) : AC(7)

Ancestral folate promotes neuronal regeneration in serial generations of progeny.

Article Published Date : Jan 09, 2020
Study Type : Animal Study
Additional Links
Substances : Folate : CK(353) : AC(53)
Diseases : Folic Acid/Folate Deficiency : CK(129) : AC(19)
Pharmacological Actions : Regenerative : CK(52) : AC(28)
Additional Keywords : DNA Methylation : CK(104) : AC(25), Nerve Regeneration : CK(26) : AC(9), Transgenerational Epigenetic Modification : CK(69) : AC(32), Transgenerational inheritance

Ancestral plastics exposure induces transgenerational disease-specific sperm epigenome-wide association biomarkers.

Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(1832) : AC(549)
Additional Keywords : Risk Factors : CK(3057) : AC(392), Transgenerational inheritance
Problem Substances : Bisphenol A : CK(2216) : AC(646)

Atrazine has the capacity to promote the epigenetic transgenerational inheritance of disease.

Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Diseases : Pesticide Toxicity : CK(192) : AC(61)
Additional Keywords : Transgenerational Epigenetic Modification : CK(69) : AC(32), Transgenerational inheritance
Problem Substances : Pesticides : CK(827) : AC(95)

Developmental exposure to lead induces transgenerational changes to zebrafish brain transcriptome.

Article Published Date : Dec 01, 2019
Study Type : Animal Study
Additional Links
Diseases : Prenatal Chemical Exposures : CK(1220) : AC(265)
Additional Keywords : Gene Expression : CK(93) : AC(46), Transgenerational inheritance
Problem Substances : Lead : CK(167) : AC(32)
Adverse Pharmacological Actions : Neurotoxic : CK(1458) : AC(323)

Dioxin induces epigenetic transgenerational inheritance of adult onset disease and sperm epimutations.

Article Published Date : Dec 31, 2011
Study Type : Animal Study
Additional Links
Diseases : Dioxin Toxicity : CK(25) : AC(10), Fetal Origin of Adult Disease : CK(103) : AC(23), Prenatal Chemical Exposures : CK(1220) : AC(265)
Additional Keywords : Risk Factors : CK(3057) : AC(392), Transgenerational inheritance
Problem Substances : Dioxins : CK(28) : AC(9)

Epigenome-wide association study for glyphosate induced transgenerational sperm DNA methylation and histone retention epigenetic biomarkers for disease.

Article Published Date : Dec 08, 2020
Study Type : Animal Study
Additional Links
Diseases : Glyphosate Toxicity : CK(76) : AC(30)
Additional Keywords : Transgenerational Epigenetic Modification : CK(69) : AC(32), Transgenerational inheritance
Problem Substances : Glyphosate : CK(716) : AC(241)

Hydrocarbons (jet fuel JP-8) induce epigenetic transgenerational inheritance of obesity, reproductive disease and sperm epimutations.

Article Published Date : Mar 31, 2013
Study Type : Animal Study
Additional Links
Diseases : Hair Loss : CK(101) : AC(26), Infertility: Male : CK(802) : AC(194), Obesity : CK(4406) : AC(1073), Polycystic Ovary Syndrome : CK(346) : AC(43)
Additional Keywords : DNA Methylation : CK(104) : AC(25), Increased Risk : CK(1600) : AC(192), Transgenerational inheritance
Problem Substances : Hydrocarbons : CK(48) : AC(20), Jet fuel : CK(6) : AC(3)

Maternal exposure to environmental bisphenol A impairs the neurons in hippocampus across generations.

Article Published Date : Feb 02, 2020
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(1832) : AC(549), Prenatal Chemical Exposures : CK(1220) : AC(265)
Additional Keywords : Transgenerational inheritance
Problem Substances : Bisphenol A : CK(2216) : AC(646)

Maternal vitamin B12 deficiency in rats alters DNA methylation in metabolically important genes in their offspring.

Article Published Date : Apr 30, 2020
Study Type : Animal Study
Additional Links
Diseases : Vitamin B 12 Deficiency : CK(301) : AC(46)
Additional Keywords : DNA Methylation : CK(104) : AC(25), Gene Expression : CK(93) : AC(46), Transgenerational inheritance

Mercury-induced epigenetic transgenerational inheritance of abnormal neurobehavior is correlated with sperm epimutations in zebrafish.

Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Diseases : Infertility: Male : CK(802) : AC(194)
Additional Keywords : DNA Methylation : CK(104) : AC(25), Transgenerational inheritance
Problem Substances : Mercury : CK(237) : AC(38)

Multigenerational impacts of gestational bisphenol A exposure on the sperm function and fertility of male mice.

Article Published Date : Mar 31, 2021
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(1832) : AC(549), Infertility: Male : CK(802) : AC(194), Prenatal Chemical Exposures : CK(1220) : AC(265)
Additional Keywords : Transgenerational inheritance
Problem Substances : Bisphenol A : CK(2216) : AC(646)

Paraquat exposure over generation affects lifespan and reproduction through mitochondrial disruption in C. elegans.

Article Published Date : Jan 14, 2021
Study Type : Animal Study
Additional Links
Diseases : Herbicide Toxicity : CK(12) : AC(7), Infertility : CK(1359) : AC(316)
Additional Keywords : Transgenerational inheritance
Problem Substances : Paraquat : CK(10) : AC(5)

Passing experiences on to future generations: endocrine disruptors and transgenerational inheritance of epimutations in brain and sperm.

Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Additional Keywords : Transgenerational inheritance
Problem Substances : Endocrine Disruptors : CK(1) : AC(1), Polychlorinated biphenyls (PCBs) : CK(244) : AC(32)

Paternal inheritance of bisphenol A cardiotoxic effects: The implications of sperm epigenome.

Article Published Date : Feb 19, 2021
Study Type : Animal Study
Additional Links
Substances : EGCG (Epigallocatechin gallate) : CK(890) : AC(477)
Diseases : Bisphenol Toxicity : CK(1832) : AC(549), Fetal Origin of Adult Disease : CK(103) : AC(23)
Pharmacological Actions : Cytoprotective : CK(190) : AC(94)
Additional Keywords : Transgenerational inheritance
Problem Substances : Bisphenol A : CK(2216) : AC(646)
Adverse Pharmacological Actions : Cardiotoxic : CK(810) : AC(124)

Prenatal exposure to a phthalate mixture leads to multigenerational and transgenerational effects on uterine morphology and function in mice.

Article Published Date : Feb 28, 2020
Study Type : Animal Study
Additional Links
Diseases : Phthalate Toxicity : CK(63) : AC(17), Prenatal Chemical Exposures : CK(1220) : AC(265)
Additional Keywords : Transgenerational inheritance
Problem Substances : Phthalates : CK(252) : AC(44)

Preterm birth is associated with epigenetic programming of transgenerational hypertension in mice.

Article Published Date : Jan 23, 2020
Study Type : Animal Study
Additional Links
Diseases : Hypertension : CK(4573) : AC(670), Premature Birth : CK(424) : AC(45)
Additional Keywords : Risk Factors : CK(3057) : AC(392), Transgenerational Epigenetic Modification : CK(69) : AC(32), Transgenerational inheritance

Small RNAs in the transgenerational inheritance of epigenetic information.

Article Published Date : Jan 13, 2020
Study Type : In Vitro Study
Additional Links
Additional Keywords : Epigenetic Modification : CK(329) : AC(127), Transgenerational inheritance

The data revealed that the endogenous opioid system may be altered in the offspring of morphine-treated parent.

Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Diseases : Prenatal Chemical Exposures : CK(1220) : AC(265)
Additional Keywords : Transgenerational inheritance
Problem Substances : Morphine : CK(20) : AC(12)

The effect of morphine might be transmitted to the next generation even after stop consuming morphine.

Article Published Date : Jan 16, 2020
Study Type : Animal Study
Additional Links
Diseases : Prenatal Chemical Exposures : CK(1220) : AC(265)
Additional Keywords : Transgenerational inheritance
Problem Substances : Morphine : CK(20) : AC(12)

The pesticide methoxychlor has the potential to promote the epigenetic transgenerational inheritance of disease.

Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Diseases : Obesity : CK(4406) : AC(1073), Pesticide Toxicity : CK(192) : AC(61)
Additional Keywords : Increased Risk : CK(1600) : AC(192), Transgenerational Epigenetic Modification : CK(69) : AC(32), Transgenerational inheritance
Problem Substances : Methoxychlor : CK(1) : AC(1)

Transgenerational effects on intestinal inflammation status in mice perinatally exposed to bisphenol S.

Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(1832) : AC(549), Gastrointestinal Inflammation : CK(118) : AC(41), Prenatal Chemical Exposures : CK(1220) : AC(265)
Additional Keywords : Transgenerational inheritance
Problem Substances : Bisphenol S : CK(73) : AC(31)

Transgenerational impaired male fertility with an Igf2 epigenetic defect in the rat are induced by the endocrine disruptor p,p'-DDE.

Article Published Date : Oct 31, 2014
Study Type : Animal Study
Additional Links
Diseases : Infertility: Male : CK(802) : AC(194), Sperm Quality: Low : CK(222) : AC(48)
Additional Keywords : Transgenerational inheritance
Problem Substances : Dichlorodiphenyldichloroethylene (DDE) : CK(12) : AC(2)

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