Results for Transgenerational inheritance

Analysis of indirect biomarkers of effect after exposure to low doses of bisphenol A in a study of successive generations of mice.

Article Published Date : Jan 25, 2022
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(2930) : AC(882)
Additional Keywords : Transgenerational inheritance
Problem Substances : Bisphenol A : CK(3250) : AC(951)

Ancestral dichlorodiphenyltrichloroethane (DDT) exposure promotes epigenetic transgenerational inheritance of obesity.

Article Published Date : Oct 22, 2013
Study Type : Animal Study
Additional Links
Diseases : Fetal Origin of Adult Disease : CK(246) : AC(60), Obesity : CK(6879) : AC(1686), Prenatal Chemical Exposures : CK(1774) : AC(396)
Additional Keywords : Increased Risk : CK(6996) : AC(896), Transgenerational inheritance
Problem Substances : Dichloro-diphenyl-trichloroethane (DDT) : CK(208) : AC(35)

Ancestral folate promotes neuronal regeneration in serial generations of progeny.

Article Published Date : Jan 09, 2020
Study Type : Animal Study
Additional Links
Substances : Folate : CK(355) : AC(55)
Diseases : Folic Acid/Folate Deficiency : CK(230) : AC(35)
Pharmacological Actions : Regenerative : CK(408) : AC(172)
Additional Keywords : DNA Methylation : CK(329) : AC(70), Nerve Regeneration : CK(26) : AC(9), Transgenerational Epigenetic Modification : CK(229) : AC(89), Transgenerational inheritance

Ancestral plastics exposure induces transgenerational disease-specific sperm epigenome-wide association biomarkers.

Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(2930) : AC(882)
Additional Keywords : Risk Factors : CK(12084) : AC(1737), Transgenerational inheritance
Problem Substances : Bisphenol A : CK(3250) : AC(951)

Atrazine has the capacity to promote the epigenetic transgenerational inheritance of disease.

Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Diseases : Pesticide Toxicity : CK(1245) : AC(376)
Additional Keywords : Transgenerational Epigenetic Modification : CK(229) : AC(89), Transgenerational inheritance
Problem Substances : Pesticides : CK(2214) : AC(420)

Benzo[a]pyrene-induces multigenerational changes in gene expression, behavior, and DNA methylation.

Article Published Date : Jun 14, 2023
Study Type : Animal Study
Additional Links
Diseases : Benzo[a]pyrene-induced Toxicity : CK(124) : AC(75)
Additional Keywords : Transgenerational inheritance
Problem Substances : Benzo(a)pyrene : CK(19) : AC(10)

Bisphenol S promotes fat storage in multiple generations.

Article Published Date : Nov 30, 2021
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(2930) : AC(882), Obesity : CK(6879) : AC(1686)
Additional Keywords : Transgenerational inheritance
Problem Substances : Bisphenol A : CK(3250) : AC(951)
Adverse Pharmacological Actions : Obesogenic : CK(88) : AC(18)

BPA is responsible for disrupting lipid metabolic processes in the offspring through increased lipid production, abnormal transport, and disruption of lipid catabolism.

Article Published Date : Feb 21, 2023
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(2930) : AC(882)
Additional Keywords : Transgenerational inheritance
Problem Substances : Bisphenol A : CK(3250) : AC(951)

Combinational exposure to Bisphenol A and a high-fat diet causes trans-generational Malfunction of the female reproductive system.

Article Published Date : Nov 12, 2021
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(2930) : AC(882), High Fat Diet : CK(1267) : AC(602), Infertility: Female : CK(541) : AC(127)
Additional Keywords : Risk Factors : CK(12084) : AC(1737), Transgenerational inheritance
Problem Substances : Bisphenol A : CK(3250) : AC(951)

Developmental exposure to lead induces transgenerational changes to zebrafish brain transcriptome.

Article Published Date : Dec 01, 2019
Study Type : Animal Study
Additional Links
Diseases : Prenatal Chemical Exposures : CK(1774) : AC(396)
Additional Keywords : Gene Expression : CK(270) : AC(101), Transgenerational inheritance
Problem Substances : Lead : CK(526) : AC(162)
Adverse Pharmacological Actions : Neurotoxic : CK(2424) : AC(562)

Developmental toxicity of bisphenol S in Caenorhabditis elegans and NODEF mice.

Article Published Date : Nov 30, 2021
Study Type : Animal Study
Additional Links
Diseases : Anxiety : CK(3360) : AC(595), Bisphenol Toxicity : CK(2930) : AC(882)
Additional Keywords : Transgenerational inheritance
Problem Substances : Bisphenol S : CK(514) : AC(172)

Dioxin induces epigenetic transgenerational inheritance of adult onset disease and sperm epimutations.

Article Published Date : Dec 31, 2011
Study Type : Animal Study
Additional Links
Diseases : Dioxin Toxicity : CK(27) : AC(11), Fetal Origin of Adult Disease : CK(246) : AC(60), Prenatal Chemical Exposures : CK(1774) : AC(396)
Additional Keywords : Risk Factors : CK(12084) : AC(1737), Transgenerational inheritance
Problem Substances : Dioxins : CK(28) : AC(9)

Epigenome-wide association study for glyphosate induced transgenerational sperm DNA methylation and histone retention epigenetic biomarkers for disease.

Article Published Date : Dec 08, 2020
Study Type : Animal Study
Additional Links
Diseases : Glyphosate Toxicity : CK(394) : AC(151)
Additional Keywords : Transgenerational Epigenetic Modification : CK(229) : AC(89), Transgenerational inheritance
Problem Substances : Glyphosate : CK(895) : AC(304)

Gestational exposure to bisphenol S induces microvesicular steatosis in male rat offspring by modulating metaflammation.

Article Published Date : Aug 31, 2023
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(2930) : AC(882), Inflammation : CK(9572) : AC(3089)
Additional Keywords : Transgenerational inheritance
Problem Substances : Bisphenol S : CK(514) : AC(172)

Gestational low-dose BPA exposure impacts suprachiasmatic nucleus neurogenesis and circadian activity with transgenerational effects.

Article Published Date : Apr 30, 2021
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(2930) : AC(882)
Additional Keywords : Transgenerational inheritance
Problem Substances : Bisphenol A : CK(3250) : AC(951)

Glyphosate differentially affects the allergic immune response across generations in mice.

Article Published Date : Aug 10, 2022
Study Type : Animal Study
Additional Links
Diseases : Glyphosate Toxicity : CK(394) : AC(151)
Additional Keywords : Transgenerational inheritance
Problem Substances : Glyphosate : CK(895) : AC(304)
Adverse Pharmacological Actions : Immunotoxic : CK(460) : AC(104)

Glyphosate herbicide: reproductive outcomes and multigenerational effects.

Article Published Date : Dec 31, 2020
Study Type : Review
Additional Links
Diseases : Glyphosate Toxicity : CK(394) : AC(151), Infertility: Female : CK(541) : AC(127)
Additional Keywords : Transgenerational inheritance
Problem Substances : Glyphosate : CK(895) : AC(304)

Hydrocarbons (jet fuel JP-8) induce epigenetic transgenerational inheritance of obesity, reproductive disease and sperm epimutations.

Article Published Date : Mar 31, 2013
Study Type : Animal Study
Additional Links
Diseases : Hair Loss : CK(293) : AC(69), Infertility: Male : CK(1286) : AC(320), Obesity : CK(6879) : AC(1686), Polycystic Ovary Syndrome : CK(1093) : AC(163)
Additional Keywords : DNA Methylation : CK(329) : AC(70), Increased Risk : CK(6996) : AC(896), Transgenerational inheritance
Problem Substances : Hydrocarbons : CK(52) : AC(22), Jet fuel : CK(8) : AC(4)

Influence of the maternal high-intensity-interval-training on the cardiac Sirt6 and lipid profile of the adult male offspring in rats.

Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Diseases : Cardiovascular Diseases : CK(12780) : AC(1983)
Pharmacological Actions : Insulin-Like Growth Factor Inhibition/Downregulation : CK(86) : AC(18)
Additional Keywords : Epigenetic Inheritance, Transgenerational inheritance

Learning and memory deficits produced by aspartame are heritable via the paternal lineage.

Article Published Date : Aug 30, 2023
Study Type : Animal Study
Additional Links
Diseases : Memory Disorders : CK(1067) : AC(339)
Additional Keywords : Transgenerational inheritance
Problem Substances : Aspartame : CK(216) : AC(77)

Low dose prenatal bisphenol A exposure on adiposity in male and female ICR offspring.

Article Published Date : May 31, 2023
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(2930) : AC(882), Obesity : CK(6879) : AC(1686), Prenatal Chemical Exposures : CK(1774) : AC(396)
Additional Keywords : Transgenerational inheritance
Problem Substances : Bisphenol A : CK(3250) : AC(951)

Maternal exposure to environmental bisphenol A impairs the neurons in hippocampus across generations.

Article Published Date : Feb 02, 2020
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(2930) : AC(882), Prenatal Chemical Exposures : CK(1774) : AC(396)
Additional Keywords : Transgenerational inheritance
Problem Substances : Bisphenol A : CK(3250) : AC(951)

Maternal vitamin B12 deficiency in rats alters DNA methylation in metabolically important genes in their offspring.

Article Published Date : Apr 30, 2020
Study Type : Animal Study
Additional Links
Diseases : Vitamin B 12 Deficiency : CK(656) : AC(91)
Additional Keywords : DNA Methylation : CK(329) : AC(70), Gene Expression : CK(270) : AC(101), Transgenerational inheritance

Mercury-induced epigenetic transgenerational inheritance of abnormal neurobehavior is correlated with sperm epimutations in zebrafish.

Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Diseases : Infertility: Male : CK(1286) : AC(320)
Additional Keywords : DNA Methylation : CK(329) : AC(70), Transgenerational inheritance
Problem Substances : Mercury : CK(808) : AC(185)

Multi- and transgenerational biochemical effects of low-dose exposure to bisphenol A and 4-nonylphenol on testicular interstitial (Leydig) cells.

Article Published Date : Jan 09, 2022
Study Type : In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity : CK(2930) : AC(882)
Additional Keywords : Transgenerational inheritance
Problem Substances : Bisphenol A : CK(3250) : AC(951)

Multigenerational impacts of gestational bisphenol A exposure on the sperm function and fertility of male mice.

Article Published Date : Mar 31, 2021
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(2930) : AC(882), Infertility: Male : CK(1286) : AC(320), Prenatal Chemical Exposures : CK(1774) : AC(396)
Additional Keywords : Transgenerational inheritance
Problem Substances : Bisphenol A : CK(3250) : AC(951)

Paraquat exposure over generation affects lifespan and reproduction through mitochondrial disruption in C. elegans.

Article Published Date : Jan 14, 2021
Study Type : Animal Study
Additional Links
Diseases : Herbicide Toxicity : CK(12) : AC(7), Infertility : CK(2080) : AC(496)
Additional Keywords : Transgenerational inheritance
Problem Substances : Paraquat : CK(10) : AC(5)

Passing experiences on to future generations: endocrine disruptors and transgenerational inheritance of epimutations in brain and sperm.

Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Additional Keywords : Transgenerational inheritance
Problem Substances : Endocrine Disruptors : CK(1) : AC(1), Polychlorinated biphenyls (PCBs) : CK(320) : AC(50)

Paternal inheritance of bisphenol A cardiotoxic effects: The implications of sperm epigenome.

Article Published Date : Feb 19, 2021
Study Type : Animal Study
Additional Links
Substances : EGCG (Epigallocatechin gallate) : CK(1091) : AC(605)
Diseases : Bisphenol Toxicity : CK(2930) : AC(882), Fetal Origin of Adult Disease : CK(246) : AC(60)
Pharmacological Actions : Cytoprotective : CK(659) : AC(326)
Additional Keywords : Transgenerational inheritance
Problem Substances : Bisphenol A : CK(3250) : AC(951)
Adverse Pharmacological Actions : Cardiotoxic : CK(1000) : AC(164)

Perinatal exposure to bisphenol A impairs cognitive function via the gamma-aminobutyric acid signaling pathway in male rat offspring.

Article Published Date : Nov 04, 2023
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(2930) : AC(882), Cognitive Decline/Dysfunction : CK(3236) : AC(654)
Additional Keywords : Transgenerational inheritance
Problem Substances : Bisphenol A : CK(3250) : AC(951)

Preconceptional exposure of adult male rats to bisphenol S impairs insulin sensitivity and glucose tolerance in their male offspring.

Article Published Date : Jan 31, 2023
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(2930) : AC(882), Insulin Resistance : CK(3522) : AC(792), Prenatal Chemical Exposures : CK(1774) : AC(396)
Additional Keywords : Transgenerational inheritance

Prenatal bisphenol S exposure induces hepatic lipid deposition in male mice offspring.

Article Published Date : Jul 04, 2023
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(2930) : AC(882), Liver Damage : CK(2494) : AC(1121), Obesity : CK(6879) : AC(1686)
Additional Keywords : Transgenerational inheritance
Problem Substances : Bisphenol S : CK(514) : AC(172)

Prenatal exposure to a phthalate mixture leads to multigenerational and transgenerational effects on uterine morphology and function in mice.

Article Published Date : Feb 28, 2020
Study Type : Animal Study
Additional Links
Diseases : Phthalate Toxicity : CK(63) : AC(17), Prenatal Chemical Exposures : CK(1774) : AC(396)
Additional Keywords : Transgenerational inheritance
Problem Substances : Phthalates : CK(1031) : AC(187)

Prenatal exposure to bisphenol S and bisphenol a differentially affects male reproductive system in the adult offspring.

Article Published Date : Jul 12, 2022
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(2930) : AC(882), Infertility: Male : CK(1286) : AC(320), Prenatal Chemical Exposures : CK(1774) : AC(396)
Additional Keywords : Transgenerational inheritance
Problem Substances : Bisphenol A : CK(3250) : AC(951)

Preterm birth is associated with epigenetic programming of transgenerational hypertension in mice.

Article Published Date : Jan 23, 2020
Study Type : Animal Study
Additional Links
Diseases : Hypertension : CK(6384) : AC(950), Premature Birth : CK(558) : AC(61)
Additional Keywords : Risk Factors : CK(12084) : AC(1737), Transgenerational Epigenetic Modification : CK(229) : AC(89), Transgenerational inheritance

Small RNAs in the transgenerational inheritance of epigenetic information.

Article Published Date : Jan 13, 2020
Study Type : In Vitro Study
Additional Links
Additional Keywords : Epigenetic Modification : CK(417) : AC(164), Transgenerational inheritance

The data revealed that the endogenous opioid system may be altered in the offspring of morphine-treated parent.

Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Diseases : Prenatal Chemical Exposures : CK(1774) : AC(396)
Additional Keywords : Transgenerational inheritance
Problem Substances : Morphine : CK(110) : AC(40)

The effect of morphine might be transmitted to the next generation even after stop consuming morphine.

Article Published Date : Jan 16, 2020
Study Type : Animal Study
Additional Links
Diseases : Prenatal Chemical Exposures : CK(1774) : AC(396)
Additional Keywords : Transgenerational inheritance
Problem Substances : Morphine : CK(110) : AC(40)

The pesticide methoxychlor has the potential to promote the epigenetic transgenerational inheritance of disease.

Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Diseases : Obesity : CK(6879) : AC(1686), Pesticide Toxicity : CK(1245) : AC(376)
Additional Keywords : Increased Risk : CK(6996) : AC(896), Transgenerational Epigenetic Modification : CK(229) : AC(89), Transgenerational inheritance
Problem Substances : Methoxychlor : CK(3) : AC(2)

These results suggested that maternal exposure to BPA at enviromentally relavant concnetrations reduces reproductive function in Drosophila melanogaster females.

Article Published Date : Aug 31, 2021
Study Type : In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity : CK(2930) : AC(882)
Additional Keywords : Transgenerational inheritance
Problem Substances : Bisphenol A : CK(3250) : AC(951)

Transgenerational effects on intestinal inflammation status in mice perinatally exposed to bisphenol S.

Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(2930) : AC(882), Gastrointestinal Inflammation : CK(261) : AC(117), Prenatal Chemical Exposures : CK(1774) : AC(396)
Additional Keywords : Transgenerational inheritance
Problem Substances : Bisphenol S : CK(514) : AC(172)

Transgenerational impaired male fertility with an Igf2 epigenetic defect in the rat are induced by the endocrine disruptor p,p'-DDE.

Article Published Date : Oct 31, 2014
Study Type : Animal Study
Additional Links
Diseases : Infertility: Male : CK(1286) : AC(320), Sperm Quality: Low : CK(536) : AC(100)
Additional Keywords : Transgenerational inheritance
Problem Substances : Dichlorodiphenyldichloroethylene (DDE) : CK(51) : AC(11)

Vitamin C supplementation during pregnancy resulted in significantly increased airway function of offspring at age 5 years and significantly decreased the occurrence of wheeze.

Article Published Date : Dec 31, 2022
Study Type : Human Study
Additional Links
Substances : Vitamin C : CK(4687) : AC(1149)
Diseases : Asthma: Childhood : CK(134) : AC(13), Pregnancy Complications : CK(554) : AC(73), Smoking : CK(1226) : AC(220)
Additional Keywords : Transgenerational inheritance

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