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Insulin induces the expression of delta-5 desaturase (FADS1) in a dose-dependent manner which may explain insulin's regulation of dihomo-gamma-linoleic acid to inflammatory arachidonic acid.

Article Published Date : Jul 01, 2011

Study Type : In Vitro Study

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Additional Keywords : arachidonic acid, Dose Response : CK(1770) : AC(700), High Sugar Diet, hyperinsulinemia, Inflammation : CK(128) : AC(57), Insulin Resistance

Problem Substances : Insulin : CK(502) : AC(87)

Adverse Pharmacological Actions : Endocrine Disruptor: Insulin Resistance : CK(151) : AC(37), Inflammatory : CK(554) : AC(176)

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