Results for Neurodegenerative diseases

Aluminium has been demonstrated to impact the CNS at every level, including by changing gene expression.

Article Published Date : Dec 31, 2013
Study Type : Review
Additional Links
Diseases : Aluminum Toxicity : CK(735) : AC(318), Autoimmune Diseases : CK(12040) : AC(2692), Neurodegenerative Diseases : CK(13103) : AC(4279)
Additional Keywords : aluminum, aluminum toxicity, Autoimmune Diseases, Gene Expression : CK(286) : AC(106), Neurodegenerative diseases, Vaccine Adjuvants
Anti Therapeutic Actions : Vaccination: All : CK(12701) : AC(1349)
Problem Substances : Aluminum : CK(1075) : AC(356), Vaccine Adjuvants : CK(1301) : AC(335)

Ancient Medical Miracle Rediscovered by Modern Science - Laurus Nobilis

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Saturday, September 7, 2013 - 11:10
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Ancient Medical Miracle Rediscovered by Modern Science - Laurus Nobilis

 

 

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Black pepper significantly improved memory in aluminum chloride induced neurotoxicity mouse model.

Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Black Pepper : CK(735) : AC(333)
Diseases : Aluminum Toxicity : CK(735) : AC(318), Neurodegenerative Diseases : CK(13103) : AC(4279), Oxidative Stress : CK(14758) : AC(5716)
Pharmacological Actions : Neuroprotective Agents : CK(20061) : AC(7949)
Additional Keywords : aluminum toxicity, Black Pepper, Neurodegenerative diseases, Neuroprotective Agents, oxidative stress, Plant Extracts : CK(18762) : AC(6782)
Problem Substances : Aluminum Chloride : CK(192) : AC(95)

Chlorpyrifos can decrease the viability of adipose tissue-derived stem cells-derived neurons and dysregulate the expression of some neuronal markers.

Article Published Date : Oct 31, 2016
Study Type : In Vitro Study
Additional Links
Diseases : Neurodegenerative Diseases : CK(13103) : AC(4279), Pesticide Toxicity : CK(1467) : AC(478)
Additional Keywords : Chlorpyrifos, Neurodegenerative diseases, Pesticide Toxicity
Problem Substances : Chlorpyrifos : CK(230) : AC(87)

Chronic exposure to electromagnetic waves results in neuronal degeneration of the auditory system.

Article Published Date : Aug 01, 2015
Study Type : Animal Study
Additional Links
Additional Keywords : electromagnetic fields, electromagnetic radiation, EMF, Neurodegenerative diseases
Anti Therapeutic Actions : Electromagnetic Field Harms : CK(4896) : AC(1009), Electromagnetic Radiation : CK(4987) : AC(989)
Adverse Pharmacological Actions : Neurotoxic : CK(2966) : AC(725)

Eugenol prevents amyloid formation of proteins and inhibits amyloid-induced hemolysis.

Article Published Date : Jan 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Eugenol : CK(219) : AC(133)
Diseases : Alzheimer's Disease : CK(5355) : AC(2210), Neurodegenerative Diseases : CK(13103) : AC(4279)
Pharmacological Actions : Neuroprotective Agents : CK(20061) : AC(7949)
Additional Keywords : Alzheimer's disease, eugenol, Neurodegenerative diseases, Neuroprotective Agents

In Defense of Coconut Oil: Rebuttal to USA Today

Post date:
Tuesday, June 20, 2017 - 06:28

In Defense of Coconut Oil: Rebuttal to USA Today

By now, I'm sure you've seen the USA Today article entitled, "Coconut oil isn't healthy. It's never been healthy". Fear-mongering, attention-grabbing headlines certainly sell copy, but do not make for evidence-informed, high quality science reporting.

As I expressed in my recent post on social media,

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Intake of fisetin during pregnancy in rats ameliorated in utero mercury exposure induced neurotoxicity outcomes.

Article Published Date : May 31, 2017
Study Type : Animal Study
Additional Links
Substances : Fisetin : CK(441) : AC(275), Flavonoids : CK(4698) : AC(2176)
Diseases : Mercury Poisoning : CK(546) : AC(159), Neurodegenerative Diseases : CK(13103) : AC(4279), Oxidative Stress : CK(14758) : AC(5716), Prenatal Chemical Exposures : CK(2485) : AC(547)
Pharmacological Actions : Neuroprotective Agents : CK(20061) : AC(7949)
Additional Keywords : Fisetin, Flavonoids, Mercury Poisoning, Methylmercury : CK(68) : AC(28), Neurodegenerative diseases, oxidative stress, Prenatal Chemical Exposures
Problem Substances : Mercury : CK(889) : AC(215)

Naringenin-induced enhanced antioxidant defence system meliorates cholinergic neurotransmission and consolidates memory in male rats.

Article Published Date : Dec 25, 2017
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(7239) : AC(3319), Naringenin : CK(704) : AC(394), Quercetin : CK(1876) : AC(855)
Diseases : Neurodegenerative Diseases : CK(13103) : AC(4279)
Pharmacological Actions : Antioxidants : CK(34551) : AC(14499), Neuroprotective Agents : CK(20061) : AC(7949)
Additional Keywords : Antioxidants : CK(303) : AC(126), CURCUMIN : CK(25) : AC(18), Naringenin, Neurodegenerative diseases, Neuroprotective Agents, QUERCETIN

Royal jelly is well known for its protective effects on reproductive health, neurodegenerative disorders, wound healing, and aging.

Article Published Date : Dec 31, 2016
Study Type : Review
Additional Links
Substances : Bee Propolis : CK(883) : AC(290), Honey : CK(1187) : AC(309), Royal Jelly : CK(636) : AC(235)
Diseases : Aging : CK(6221) : AC(1510), Neurodegenerative Diseases : CK(13103) : AC(4279), Wound Healing : CK(4555) : AC(1412)
Pharmacological Actions : Anti-Inflammatory Agents : CK(39737) : AC(15858), Neuroprotective Agents : CK(20061) : AC(7949)
Additional Keywords : Aging, Anti-Inflammatory Agents, bee propolis, Honey : CK(22) : AC(9), Neurodegenerative diseases, Neuroprotective Agents, Royal Jelly, wound healing

Sulforphane's antioxidant properties make it an effective neuroprotective agent. More studies are needed to determine the exact implications in neurological disease.

Article Published Date : Apr 01, 2019
Study Type : Review
Additional Links
Substances : Sulforaphane : CK(1344) : AC(630)
Therapeutic Actions : antioxidant, antioxidants, neuro-protective
Pharmacological Actions : Antioxidant, Antioxidant Effects : CK(159) : AC(45), Antioxidants : CK(34551) : AC(14499), Neuroprotective Agents : CK(20061) : AC(7949), NF-E2-Related Factor-2 (Nrf2) Modulator : CK(72) : AC(41), Nrf2 activation : CK(3156) : AC(1794)
Additional Keywords : Antioxidant effects, Antioxidant Systems : CK(3) : AC(3), Cruciferous Vegetables, Neurodegenerative diseases, Neuroprotective Agents, Nrf2 activation, Phytotherapy : CK(4003) : AC(1031), Sulforaphane

The critical review results indicate that compounds in avocado are unique antioxidants, and thus may be promising as effective neuropreventive agents.

Article Published Date : Dec 31, 2015
Study Type : Review
Additional Links
Substances : Avocado : CK(199) : AC(62)
Diseases : Alzheimer's Disease : CK(5355) : AC(2210), Amyotrophic lateral sclerosis (ALS) : CK(793) : AC(216), Huntington Disease : CK(222) : AC(103), Neurodegenerative Diseases : CK(13103) : AC(4279), Parkinson's Disease : CK(3012) : AC(1116)
Pharmacological Actions : Antioxidants : CK(34551) : AC(14499), Neuroprotective Agents : CK(20061) : AC(7949)
Additional Keywords : Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Avocado, Huntington Disease, Neurodegenerative diseases, Parkinson's disease

These results indicate that SIRT1 and TORC1 might play an important mediating role in aluminium -induced long-term memory impairment.

Article Published Date : Sep 30, 2017
Study Type : Animal Study
Additional Links
Diseases : Aluminum Toxicity : CK(735) : AC(318), Memory Disorders : CK(1795) : AC(559), Neurodegenerative Diseases : CK(13103) : AC(4279)
Additional Keywords : aluminum, aluminum toxicity, Memory Disorders, Neurodegenerative diseases
Problem Substances : Aluminum : CK(1075) : AC(356)

Thymoquinone protects against cobalt chloride-induced neurotoxicity.

Article Published Date : Sep 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Thymoquinone : CK(1178) : AC(692)
Diseases : Neurodegenerative Diseases : CK(13103) : AC(4279)
Pharmacological Actions : Antioxidants : CK(34551) : AC(14499), Neuroprotective Agents : CK(20061) : AC(7949), Nrf2 activation : CK(3156) : AC(1794)
Additional Keywords : Antioxidants : CK(303) : AC(126), Cobalt, Neurodegenerative diseases, Neuroprotective Agents, Nrf2 activation, thymoquinone
Problem Substances : Cobalt : CK(21) : AC(14)

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