Results for thymoquinone

Administration of thymoquinone reduced renal fibrosis and permeability and improved oxidative stress status.

Article Published Date : Nov 30, 2017
Study Type : Animal Study
Additional Links
Substances : Thymoquinone : CK(774) : AC(451)
Diseases : Kidney Fibrosis : CK(121) : AC(68)
Pharmacological Actions : Anti-Fibrotic : CK(924) : AC(463), Antioxidants : CK(21528) : AC(8856)
Additional Keywords : Anti-Fibrotic, Antioxidants : CK(303) : AC(126), Kidney Fibrosis, thymoquinone

Forced inhibition of PDE1A expression might be a new therapeutic strategy for the management of acute lymphoblastic leukemia.

Article Published Date : Dec 31, 2010
Study Type : In Vitro Study
Additional Links
Substances : Thymoquinone : CK(774) : AC(451)
Diseases : Acute lymphoblastic leukemia (ALL) : CK(193) : AC(72)
Pharmacological Actions : Antineoplastic Agents : CK(1847) : AC(1170), Apoptotic : CK(6986) : AC(5304)
Additional Keywords : Acute lymphoblastic leukemia (ALL), Antineoplastic Agents : CK(78) : AC(35), Apoptotic, thymoquinone

N. sativa and thymoquinone may prove clinically useful in the treatment of diabetics and in the protection of β-cells against oxidative stress.

Article Published Date : Nov 30, 2010
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed) : CK(1250) : AC(356), Thymoquinone : CK(774) : AC(451)
Diseases : Diabetes: Oxidative Stress : CK(492) : AC(182)
Pharmacological Actions : Antioxidants : CK(21528) : AC(8856), Malondialdehyde Down-regulation : CK(2065) : AC(678), Pancreato Protective Agents : CK(358) : AC(194), Superoxide Dismutase Up-regulation : CK(1403) : AC(551)
Additional Keywords : Antioxidants : CK(303) : AC(126), Diabetes: Oxidative Stress, Nigella sativa (aka Black Seed), Phytotherapy : CK(3062) : AC(812), Plant Extracts : CK(14140) : AC(5210), thymoquinone

Nigella sativa oil and thymoquinone maybe useful in amelioration of the intestinal toxicity associated with long-term cisplatin chemotherapy.

Article Published Date : Jan 03, 2018
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed) : CK(1250) : AC(356), Thymoquinone : CK(774) : AC(451)
Diseases : Chemotherapy-Induced Toxicity: Cisplatin : CK(881) : AC(388)
Pharmacological Actions : Chemoprotective Agents : CK(2322) : AC(906)
Additional Keywords : Chemoprotective Agents, Chemotherapy-Induced Toxicity: Cisplatin, Nigella sativa (aka Black Seed), thymoquinone

These findings strongly suggest that the anti-inflammatory actions of Thymoquinone are caused by suppression of IRAK-linked AP-1/NF-κB pathways.

Article Published Date : Feb 19, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Thymoquinone : CK(774) : AC(451)
Diseases : Inflammation : CK(9572) : AC(3089)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Cyclooxygenase 2 Inhibitors : CK(1589) : AC(926), Interleukin-1 beta downregulation : CK(3041) : AC(1567), Interleukin-6 Downregulation : CK(5029) : AC(1994), NF-kappaB Inhibitor : CK(3536) : AC(2098), Nitric Oxide Inhibitor : CK(498) : AC(258), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(6736) : AC(2815)
Additional Keywords : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Inflammation : CK(128) : AC(57), Interleukin-1 beta downregulation, thymoquinone

Thymoquinone abolishes a number of factors known to be involved in rheumatoid arthritis pathogenesis.

Article Published Date : Dec 31, 2010
Study Type : Animal Study
Additional Links
Substances : Thymoquinone : CK(774) : AC(451)
Diseases : Inflammation : CK(9572) : AC(3089), Rheumatoid Arthritis : CK(1546) : AC(328)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Antiproliferative : CK(6801) : AC(5032), Cyclooxygenase 2 Inhibitors : CK(1589) : AC(926), Interleukin-1 beta downregulation : CK(3041) : AC(1567), NF-kappaB Inhibitor : CK(3536) : AC(2098), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(6736) : AC(2815)
Additional Keywords : Anti-Inflammatory Agents, Antiproliferative : CK(65) : AC(52), Inflammation : CK(128) : AC(57), rheumatoid arthritis, thymoquinone

Thymoquinone inhibits proliferation, induces apoptosis and chemosensitizes human multiple myeloma cells.

Article Published Date : Sep 30, 2010
Study Type : In Vitro Study
Additional Links
Substances : Thymoquinone : CK(774) : AC(451)
Diseases : Multiple Myeloma : CK(330) : AC(129)
Pharmacological Actions : Antineoplastic Agents : CK(1847) : AC(1170), Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304), Chemosensitizer : CK(1124) : AC(854), Interleukin-6 Downregulation : CK(5029) : AC(1994), STAT3 Inhibitor : CK(53) : AC(31)
Additional Keywords : Antineoplastic Agents : CK(78) : AC(35), Antiproliferative : CK(65) : AC(52), Apoptotic, Multiple Myeloma, thymoquinone

Thymoquinone inhibits the migration and invasion of cervical cancer cells.

Article Published Date : Dec 03, 2017
Study Type : In Vitro Study
Additional Links
Substances : Thymoquinone : CK(774) : AC(451)
Diseases : Cervical Cancer : CK(756) : AC(422)
Pharmacological Actions : Anti-metastatic : CK(1972) : AC(1481)
Additional Keywords : Anti-metastatic, Cervical Cancer, thymoquinone

Thymoquinone is a promising agent in the treatment of head and neck cancer due to its anti-proliferative and radiosensitizing properties.

Article Published Date : Jun 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Thymoquinone : CK(774) : AC(451)
Diseases : Head and Neck Cancer : CK(459) : AC(118)
Pharmacological Actions : Antiproliferative : CK(6801) : AC(5032), Radiosensitizer : CK(291) : AC(182)
Additional Keywords : Antiproliferative : CK(65) : AC(52), Head and Neck Cancer, Radiosensitizer, thymoquinone

Thymoquinone may be considered for topical application alone in the treatment of acute otitis externa.

Article Published Date : Dec 13, 2017
Study Type : Animal Study
Additional Links
Substances : Thymoquinone : CK(774) : AC(451)
Diseases : Otitis : CK(10) : AC(1)
Pharmacological Actions : Anti-Bacterial Agents : CK(2894) : AC(1251), Anti-Inflammatory Agents : CK(20859) : AC(8334)
Additional Keywords : Anti-Bacterial Agents, Anti-Inflammatory Agents, Otitis, Superiority of Natural Substances versus Drugs : CK(1644) : AC(347), thymoquinone

Thymoquinone protects against cobalt chloride-induced neurotoxicity.

Article Published Date : Sep 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Thymoquinone : CK(774) : AC(451)
Diseases : Neurodegenerative Diseases : CK(8689) : AC(2653)
Pharmacological Actions : Antioxidants : CK(21528) : AC(8856), Neuroprotective Agents : CK(10404) : AC(4396), Nrf2 activation : CK(1584) : AC(916)
Additional Keywords : Antioxidants : CK(303) : AC(126), Cobalt, Neurodegenerative diseases, Neuroprotective Agents, Nrf2 activation, thymoquinone
Problem Substances : Cobalt : CK(15) : AC(10)

Thymoquinone use may decrease the destructive effects of methotrexate on testicular tissue of patients using this agent.

Article Published Date : Jul 31, 2011
Study Type : Animal Study
Additional Links
Substances : Thymoquinone : CK(774) : AC(451)
Diseases : Drug Toxicity: Methotrexate : CK(99) : AC(49), Lipid Peroxidation : CK(1632) : AC(631), Oxidative Stress : CK(9437) : AC(3550)
Pharmacological Actions : Antioxidants : CK(21528) : AC(8856)
Additional Keywords : Antioxidants : CK(303) : AC(126), Drug Toxicity: Methotrexate, Lipid Peroxidation, oxidative stress, thymoquinone

Treatment by Thymoquinone restores inflammation-induced liver fibrosis.

Article Published Date : Oct 31, 2017
Study Type : Animal Study
Additional Links
Substances : Thymoquinone : CK(774) : AC(451)
Diseases : Fibrosis: Liver : CK(32) : AC(13), Inflammation : CK(9572) : AC(3089), Lipopolysaccharide-Induced Toxicity : CK(1764) : AC(1073)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334)
Additional Keywords : Anti-Inflammatory Agents, Fibrosis: Liver, Inflammation : CK(128) : AC(57), Lipopolysaccharide-Induced Toxicity, thymoquinone

Connect with GreenMedInfo

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2023 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.