C-Jun N-Terminal Kinases (JNK) Modulator

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4 Substances Researched for C-Jun N-Terminal Kinases (JNK) Modulator
NameACCKFocus
Luteolin12Locked
Hesperidin11Locked
Resveratrol11Locked
Stilbenes11Locked

View the Evidence:
3 Abstracts with C-Jun N-Terminal Kinases (JNK) Modulator Research

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Luteolin inhibits LPS-induced IL-6 production in the brain by inhibiting the JNK signaling pathway and activation of AP-1 in microglia and may be useful for mitigating neuroinflammation.May 26, 2008

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Proc Natl Acad Sci U S A. 2008 May 27 ;105(21):7534-9. Epub 2008 May 19. PMID: 18490655
Article Published Date : May 26, 2008
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Luteolin
Diseases : Brain Inflammation , Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, C-Jun N-Terminal Kinases (JNK) Modulator, Interleukin-6 Downregulation, Neuroprotective Agents, NF-kappaB Inhibitor
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Hesperidin may have anti-aging properties via NF-kappaB modulation. Oct 01, 2006

Pubmed Data : Aging Cell. 2006 Oct;5(5):401-11. Epub 2006 Aug 25. PMID: 16939486
Article Published Date : Oct 01, 2006
Study Type : In Vitro Study
Additional Links
Substances : Hesperidin
Diseases : Aging
Pharmacological Actions : C-Jun N-Terminal Kinases (JNK) Modulator, Extracellular Signal-Regulated Kinases Modulator, Inhibitor of Nuclear Factor Kappa-B Kinase (IKK), NF-kappa-B-inducing kinase (NIK) modulator, NF-kappaB Inhibitor, P38 Mitogen-Activated Protein Kinase Modulator
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Resveratrol promotes autophagic cell death in chronic myelogenous leukemia cells.Feb 01, 2010

Pubmed Data : Cancer Res. 2010 Feb 1;70(3):1042-52. Epub 2010 Jan 26. PMID: 20103647
Article Published Date : Feb 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol, Stilbenes
Diseases : Cancers: Drug Resistant, Leukemia: Chronic myelogenous leukemia (CML)
Pharmacological Actions : Antineoplastic Agents, Autophagy Up-regulation, C-Jun N-Terminal Kinases (JNK) Modulator

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