Results for Cytotoxicity

Ascorbate potentiates the cytotoxicity of menadione leading to an oxidative stress that kills cancer cells.

Article Published Date : Feb 29, 2004
Study Type : In Vitro Study
Additional Links
Substances : Vitamin C : CK(4687) : AC(1149)
Diseases : Liver Cancer : CK(2460) : AC(1189)
Pharmacological Actions : Antioxidants : CK(21528) : AC(8856), Chemotherapeutic : CK(2328) : AC(1086), Cytotoxicity

Flavonoids showed a dose dependent cytotoxicity towards various types of leukemia cells in vitro.

Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Apigenin : CK(432) : AC(251), Baicalein : CK(184) : AC(112), Chrysin : CK(147) : AC(93), Flavonoids : CK(2352) : AC(870), Genistein : CK(788) : AC(365), Luteolin : CK(381) : AC(247), Naringenin : CK(358) : AC(212)
Diseases : Leukemia : CK(1709) : AC(739)
Pharmacological Actions : Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304), Cytotoxicity
Additional Keywords : Dose Response : CK(1712) : AC(683)

kaempferol induced DNA damage and suppressed DNA repair and inhibited DNA repair associated protein expression in HL-60 cells

Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Kaempferol : CK(102) : AC(65)
Diseases : Leukemia: Acute promyelocytic leukemia : CK(50) : AC(40)
Pharmacological Actions : Antiproliferative : CK(6801) : AC(5032), Cytotoxicity, Tumor Suppressor Protein p53 Upregulation : CK(585) : AC(431)
Additional Keywords : Dose Response : CK(1712) : AC(683)

Mannosylated solid lipid nanocarriers of chrysin to target gastric cancer.

Article Published Date : Mar 18, 2021
Study Type : In Vitro Study
Additional Links
Substances : Chrysin : CK(147) : AC(93)
Diseases : Gastric Cancer : CK(1165) : AC(504)
Pharmacological Actions : Cytotoxicity

Metabolic profiling study of shikonin's cytotoxic activity in the Huh7 human hepatoma cell line.

Article Published Date : May 01, 2017
Study Type : In Vitro Study
Additional Links
Substances : Shikonin : CK(108) : AC(63)
Diseases : Liver Cancer : CK(2460) : AC(1189)
Pharmacological Actions : Cytotoxicity

Multiple myeloma tumor cells are selectively killed by pharmacologically-dosed ascorbic acid.

Article Published Date : Mar 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Vitamin C : CK(4687) : AC(1149)
Diseases : Multiple Myeloma : CK(330) : AC(129), Smoldering multiple myeloma (SMM) : CK(22) : AC(3)
Pharmacological Actions : Cytotoxicity
Additional Keywords : Selective Cytotoxicity : CK(264) : AC(195)

Shikonin enhances NK cells proliferation and cytotoxicity.

Article Published Date : May 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Shikonin : CK(108) : AC(63)
Diseases : Colon Cancer : CK(1493) : AC(954)
Pharmacological Actions : Cytotoxicity, Immunomodulatory : CK(4048) : AC(1475)

Thymol elicits HCT-116 colorectal carcinoma cell death through induction of oxidative stress.

Article Published Date : Mar 26, 2017
Study Type : In Vitro Study
Additional Links
Substances : Thymol : CK(96) : AC(68)
Diseases : Colorectal Cancer : CK(3666) : AC(1651)
Pharmacological Actions : Cytotoxicity

Thymol induced Ca²⁺-dissociated cell death in prostate cancer.

Article Published Date : Jan 27, 2017
Study Type : In Vitro Study
Additional Links
Substances : Thymol : CK(96) : AC(68)
Diseases : Prostate Cancer : CK(2407) : AC(834)
Pharmacological Actions : Cytotoxicity

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