Results for Cytotoxicity

Ascorbate potentiates the cytotoxicity of menadione leading to an oxidative stress that kills cancer cells.

Article Published Date : Feb 29, 2004
Study Type : In Vitro Study
Additional Links
Substances : Vitamin C : CK(6130) : AC(1421)
Diseases : Liver Cancer : CK(3209) : AC(1677)
Pharmacological Actions : Antioxidants : CK(36205) : AC(15128), Chemotherapeutic : CK(4503) : AC(1664), Cytotoxicity

Cytotoxicity enhancement in MCF-7 breast cancer cells with depolymerized chitosan delivery of α-mangostin.

Article Published Date : Jul 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Xanthones : CK(84) : AC(66)
Diseases : Breast Cancer : CK(8444) : AC(3108)
Pharmacological Actions : Cytotoxicity

Cytotoxicity enhancement of α-mangostin with folate-conjugated chitosan nanoparticles in MCF-7 breast cancer cells.

Article Published Date : Nov 13, 2023
Study Type : In Vitro Study
Additional Links
Substances : Folate : CK(422) : AC(66), Xanthones : CK(84) : AC(66)
Diseases : Breast Cancer : CK(8444) : AC(3108)
Pharmacological Actions : Cytotoxicity

Flavonoids showed a dose dependent cytotoxicity towards various types of leukemia cells in vitro.

Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Apigenin : CK(688) : AC(398), Baicalein : CK(313) : AC(203), Chrysin : CK(446) : AC(275), Flavonoids : CK(4857) : AC(2260), Genistein : CK(947) : AC(436), Luteolin : CK(753) : AC(402), Naringenin : CK(744) : AC(409)
Diseases : Leukemia : CK(2111) : AC(926)
Pharmacological Actions : Antiproliferative : CK(10352) : AC(7744), Apoptotic : CK(9835) : AC(7583), Cytotoxicity
Additional Keywords : Dose Response : CK(1780) : AC(701)

kaempferol induced DNA damage and suppressed DNA repair and inhibited DNA repair associated protein expression in HL-60 cells

Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Kaempferol : CK(358) : AC(233)
Diseases : Leukemia: Acute promyelocytic leukemia : CK(77) : AC(52)
Pharmacological Actions : Antiproliferative : CK(10352) : AC(7744), Cytotoxicity, Tumor Suppressor Protein p53 Upregulation : CK(769) : AC(563)
Additional Keywords : Dose Response : CK(1780) : AC(701)

Mannosylated solid lipid nanocarriers of chrysin to target gastric cancer.

Article Published Date : Mar 18, 2021
Study Type : In Vitro Study
Additional Links
Substances : Chrysin : CK(446) : AC(275)
Diseases : Gastric Cancer : CK(1655) : AC(747)
Pharmacological Actions : Cytotoxicity

Metabolic profiling study of shikonin's cytotoxic activity in the Huh7 human hepatoma cell line.

Article Published Date : May 01, 2017
Study Type : In Vitro Study
Additional Links
Substances : Shikonin : CK(369) : AC(261)
Diseases : Liver Cancer : CK(3209) : AC(1677)
Pharmacological Actions : Cytotoxicity

Multiple myeloma tumor cells are selectively killed by pharmacologically-dosed ascorbic acid.

Article Published Date : Mar 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Vitamin C : CK(6130) : AC(1421)
Diseases : Multiple Myeloma : CK(438) : AC(165), Smoldering multiple myeloma (SMM) : CK(22) : AC(3)
Pharmacological Actions : Cytotoxicity
Additional Keywords : Selective Cytotoxicity : CK(274) : AC(201)

Shikonin enhances NK cells proliferation and cytotoxicity.

Article Published Date : May 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Shikonin : CK(369) : AC(261)
Diseases : Colon Cancer : CK(1943) : AC(1216)
Pharmacological Actions : Cytotoxicity, Immunomodulatory : CK(6825) : AC(2459)

Thymol elicits HCT-116 colorectal carcinoma cell death through induction of oxidative stress.

Article Published Date : Mar 26, 2017
Study Type : In Vitro Study
Additional Links
Substances : Thymol : CK(149) : AC(104)
Diseases : Colorectal Cancer : CK(5003) : AC(2343)
Pharmacological Actions : Cytotoxicity

Thymol induced Ca²⁺-dissociated cell death in prostate cancer.

Article Published Date : Jan 27, 2017
Study Type : In Vitro Study
Additional Links
Substances : Thymol : CK(149) : AC(104)
Diseases : Prostate Cancer : CK(2862) : AC(1067)
Pharmacological Actions : Cytotoxicity

Uncovering naringin's anticancer mechanisms in glioblastoma via molecular docking and network pharmacology approaches.

Article Published Date : Sep 13, 2024
Study Type : In Vitro Study
Additional Links
Substances : Citrus naringin : CK(452) : AC(252)
Diseases : Glioblastoma : CK(744) : AC(416)
Pharmacological Actions : Cytotoxicity

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