Results for Alpha Linolenic Acid

Additive anti-inflammation by a combination of conjugated linoleic acid and α-lipoic acid.

Article Published Date : Feb 29, 2020
Study Type : In Vitro Study
Additional Links
Substances : Alpha Linolenic Acid, Linoleic acid : CK(73) : AC(15)
Diseases : Inflammation : CK(16108) : AC(5498)
Pharmacological Actions : Anti-Inflammatory Agents : CK(39739) : AC(15859)
Additional Keywords : Natural Substance Synergy : CK(1402) : AC(670)

Alpha linolenic fatty acid supplementation had a beneficial effect on tumor cell proliferation and cachexia parameters.

Article Published Date : May 25, 2015
Study Type : Animal Study
Additional Links
Substances : Alpha Linolenic Acid
Diseases : Breast Cancer : CK(8297) : AC(3043), Cachexia : CK(96) : AC(36)
Pharmacological Actions : Antiproliferative : CK(10001) : AC(7491), Cyclooxygenase 2 Inhibitors : CK(2264) : AC(1327), Interleukin-6 Downregulation : CK(9337) : AC(3613), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(11697) : AC(4806)

Alpha-linolenic acid given as an anti-inflammatory agent in a mouse model of colonic inflammation.

Article Published Date : Nov 30, 2019
Study Type : Animal Study
Additional Links
Substances : Alpha Linolenic Acid
Diseases : Colitis : CK(1542) : AC(735)
Pharmacological Actions : Anti-Inflammatory Agents : CK(39739) : AC(15859), Anticholesteremic Agents : CK(4093) : AC(669), Hypolipidemic : CK(9173) : AC(2038), Immunomodulatory : CK(6531) : AC(2360)

Alpha-linolenic acid helped in controlling glycaemia in rats induced to T2DM.

Article Published Date : Nov 05, 2020
Study Type : Animal Study
Additional Links
Substances : Alpha Linolenic Acid
Diseases : Diabetes Mellitus: Type 2 : CK(12953) : AC(2579), Liver Damage : CK(4109) : AC(1872), Mitochondrial Dysfunction : CK(628) : AC(269)
Additional Keywords : Risk Factors : CK(14901) : AC(2085)

Alpha-linolenic acid protects against lipopolysaccharide-induced acute lung injury through anti-inflammatory and anti-oxidative pathways.

Article Published Date : Feb 17, 2020
Study Type : Animal Study
Additional Links
Substances : Alpha Linolenic Acid
Diseases : Lipopolysaccharide-Induced Toxicity : CK(3229) : AC(1875), Lung Injury: Acute : CK(533) : AC(253)
Pharmacological Actions : Anti-Inflammatory Agents : CK(39739) : AC(15859), Antioxidants : CK(34553) : AC(14500), Interleukin-1 beta downregulation : CK(6063) : AC(2940), Interleukin-6 Downregulation : CK(9337) : AC(3613), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(11697) : AC(4806)

Alpha-linolenic acid regulates the gut microbiota and the inflammatory environment in a model of endometriosis.

Article Published Date : May 21, 2021
Study Type : Animal Study
Additional Links
Substances : Alpha Linolenic Acid
Diseases : Endometriosis : CK(579) : AC(159)
Pharmacological Actions : Gastrointestinal Agents : CK(7667) : AC(2275), Gastroprotective : CK(1695) : AC(702)

Alpha-linolenic acidbut supplementation improves endothelial dysfunction and diminishes experimental hypertension.

Article Published Date : Feb 02, 2020
Study Type : Animal Study
Additional Links
Substances : Alpha Linolenic Acid
Diseases : Endothelial Dysfunction : CK(2733) : AC(581), Hypertension : CK(9125) : AC(1361)
Pharmacological Actions : Antihypertensive Agents : CK(7081) : AC(1029), Antioxidants : CK(34553) : AC(14500)

Consumption of alpha-lipoic acid-rich foods may prevent the development of H. pylori-associated gastric diseases.

Article Published Date : Oct 18, 2019
Study Type : In Vitro Study
Additional Links
Substances : Alpha Linolenic Acid
Diseases : Helicobacter Pylori Infection : CK(1213) : AC(275)
Pharmacological Actions : Antioxidants : CK(34553) : AC(14500), Heme oxygenase-1 up-regulation : CK(1336) : AC(776), Interleukin-8 downregulation : CK(1107) : AC(402), Nrf2 activation : CK(3156) : AC(1794)

Correlations between α-linolenic acid-improved multitissue homeostasis and gut microbiota in mice fed a high-fat diet.

Article Published Date : Nov 02, 2020
Study Type : Animal Study
Additional Links
Substances : Alpha Linolenic Acid
Diseases : High Fat Diet : CK(2040) : AC(984)
Pharmacological Actions : Gastrointestinal Agents : CK(7667) : AC(2275)

Dietary and plasma blood α-linolenic acid as modulators of fat oxidation and predictors of aerobic performance.

Article Published Date : Nov 15, 2020
Study Type : Human Study
Additional Links
Substances : Alpha Linolenic Acid
Diseases : Athletic Performance : CK(2439) : AC(282)
Therapeutic Actions : Exercise : CK(6919) : AC(1026)

Effect of alpha-linolenic acid in combination with the flavonol quercetin on markers of cardiovascular disease risk.

Article Published Date : Jan 31, 2019
Study Type : Human Study
Additional Links
Substances : Alpha Linolenic Acid, Quercetin : CK(1876) : AC(855)
Diseases : Cardiovascular Diseases : CK(17333) : AC(2878), Obesity : CK(11004) : AC(2672)
Pharmacological Actions : Anticholesteremic Agents : CK(4093) : AC(669), Cardioprotective : CK(9504) : AC(2963)

Effects of nano-α-linolenic acid and miR-146 on mice with viral myocarditis.

Article Published Date : Jan 31, 2021
Study Type : Animal Study
Additional Links
Substances : Alpha Linolenic Acid
Diseases : Myocarditis: Viral : CK(98) : AC(20)
Pharmacological Actions : Cardioprotective : CK(9504) : AC(2963), MicroRNA modulator : CK(1560) : AC(897)

Egg consumption in U.S. children is associated with greater daily nutrient intakes.

Article Published Date : May 21, 2019
Study Type : Human Study
Additional Links
Substances : Alpha Linolenic Acid, Choline : CK(99) : AC(21), DHA (Docosahexaenoic Acid) : CK(1285) : AC(244), Egg : CK(456) : AC(55), Zeaxanthin : CK(303) : AC(58)

Natural compounds against doxorubicin-induced cardiotoxicity.

Article Published Date : Sep 27, 2020
Study Type : In Vitro Study
Additional Links
Substances : Alpha Linolenic Acid, Apigenin : CK(681) : AC(392), Asiatic Acid : CK(244) : AC(155), Ferulic acid : CK(263) : AC(147), Genistein : CK(945) : AC(434), Ginsenosides : CK(2640) : AC(1452), Indole-3-Carbinol : CK(215) : AC(130), Naringenin : CK(704) : AC(394), P-Coumaric Acid : CK(88) : AC(56), Punicalagin : CK(233) : AC(139), Quercetin : CK(1876) : AC(855), Reishi Mushroom : CK(650) : AC(349), Sulforaphane : CK(1344) : AC(630), Tanshinone IIA : CK(804) : AC(494)
Diseases : Chemotherapy-Induced Toxicity: Doxorubicin : CK(845) : AC(423)
Pharmacological Actions : Antioxidants : CK(34553) : AC(14500), Cardioprotective : CK(9504) : AC(2963), Chemoprotective Agents : CK(4278) : AC(1621), Nrf2 activation : CK(3156) : AC(1794)
Additional Keywords : Polysaccharides : CK(1328) : AC(749)

Natural products may interfere With SARS-CoV-2 attachment to the host cell.

Article Published Date : May 04, 2020
Study Type : In Vitro Study
Additional Links
Substances : Alpha Linolenic Acid, Biochanin A : CK(191) : AC(114), Caffeic Acid : CK(136) : AC(87), Caffeic acid phenethyl ester : CK(284) : AC(172), Chlorogenic Acid : CK(431) : AC(189), Cinnamaldehyde : CK(213) : AC(130), Formononetin : CK(194) : AC(122), Genistein : CK(945) : AC(434), Hydroxytyrosol : CK(310) : AC(144), Thymoquinone : CK(1178) : AC(692)
Diseases : Coronavirus Infection : CK(3250) : AC(986)
Pharmacological Actions : Antiviral Agents : CK(3095) : AC(1702)

Oxidation products of alpha-linolenic acid (ALA), oxylipins, enhance the longevity-promoting properties of ALA in C. elegans.

Article Published Date : Jan 10, 2017
Study Type : Animal Study
Additional Links
Substances : Alpha Linolenic Acid
Diseases : Aging : CK(6222) : AC(1511)
Additional Keywords : epigenetics, Longevity : CK(4) : AC(2)

Perilla frutescens leaf powder intake may be an effective intervention to prevent cardiovascular diseases.

Article Published Date : Apr 29, 2020
Study Type : Human Study
Additional Links
Substances : Alpha Linolenic Acid, Perilla : CK(214) : AC(90)
Diseases : Cardiovascular Diseases : CK(17333) : AC(2878), Hypertension : CK(9125) : AC(1361)
Pharmacological Actions : Antihypertensive Agents : CK(7081) : AC(1029), Cardioprotective : CK(9504) : AC(2963)

Perilla oil and α-linolenic acid ameliorated thrombosis.

Article Published Date : May 31, 2023
Study Type : Animal Study
Additional Links
Substances : Alpha Linolenic Acid, Perilla : CK(214) : AC(90)
Diseases : Thrombosis : CK(448) : AC(123)
Pharmacological Actions : Anti-thrombotic : CK(79) : AC(34)

Protective effect of α-linolenic acid on non-alcoholic hepatic steatosis and interleukin-6 and -10 in wistar rats.

Article Published Date : Dec 17, 2019
Study Type : Animal Study
Additional Links
Substances : Alpha Linolenic Acid
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(3451) : AC(969)
Pharmacological Actions : Anti-Inflammatory Agents : CK(39739) : AC(15859), Interleukin-10 downregulation : CK(367) : AC(136), Interleukin-6 Downregulation : CK(9337) : AC(3613)

Supplementation with flaxseed oil rich in alpha-linolenic acid improves verbal fluency in healthy older adults.

Article Published Date : Mar 20, 2023
Study Type : Human Study
Additional Links
Substances : Alpha Linolenic Acid, Flaxseed : CK(1364) : AC(223)
Diseases : Alzheimer's Disease : CK(5355) : AC(2210)
Pharmacological Actions : Neuroprotective Agents : CK(20065) : AC(7951)

Therapeutic effect of alpha lipoic acid in a rat preclinical model of preeclampsia.

Article Published Date : Jun 15, 2024
Study Type : Animal Study
Additional Links
Substances : Alpha Linolenic Acid
Diseases : Pre-Eclampsia : CK(620) : AC(90)
Pharmacological Actions : Antioxidants : CK(34553) : AC(14500)

These findings suggest that alpha-linolenic acid might have the potential for therapeutics of Alzheimer's disease.

Article Published Date : May 15, 2018
Study Type : In Vitro Study
Additional Links
Substances : Alpha Linolenic Acid
Pharmacological Actions : Anti-Inflammatory Agents : CK(39739) : AC(15859), Antioxidants : CK(34553) : AC(14500), Heme oxygenase-1 up-regulation : CK(1336) : AC(776), Neuroprotective Agents : CK(20065) : AC(7951), Nrf2 activation : CK(3156) : AC(1794)

Why You Need To Supplement Essential Fatty Acids

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Tuesday, January 13, 2015 - 13:56
This article is copyrighted by GreenMedInfo LLC, 2015
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Why You Need To Supplement Essential Fatty Acids

Today, healthy fatty acid deficiency is epidemic. This deficiency leads to cardiovascular and immune issues and other disorders. What do you do if you're HFA deficient? 

[Note: Melanie Christner is leading an upcoming 12-week GAPS™ Protocol course which is still open for enrollment. Learn more here.]

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α-linolenic acid suppresses proliferation and invasion in osteosarcoma cells.

Article Published Date : Apr 23, 2022
Study Type : In Vitro Study
Additional Links
Substances : Alpha Linolenic Acid
Diseases : Osteosarcoma : CK(425) : AC(288)
Pharmacological Actions : Antiproliferative : CK(10001) : AC(7491), Apoptotic : CK(9585) : AC(7379)

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