Bromelain

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88 Diseases Researched for Bromelain
NameACCKFocus
Inflammation1740Locked
Breast Cancer720Locked
Osteoarthritis: Knee220Locked
Sinusitis220Locked
Wound Healing516Locked
Coronavirus Infection615Locked
Osteoarthritis415Locked
Lung Cancer313Locked
Thrombosis313Locked
Periodontitis212Locked
Cancers: All611Locked
Chemotherapy-Induced Toxicity: Peripheral Neuropathy110Locked
Constipation: Post-Operative110Locked
Dental Care110Locked
Dyspepsia110Locked
Edema110Locked
Endothelial Dysfunction110Locked
Hypertension110Locked
Oral Surgical Procedures110Locked
Pain110Locked
Perineal trauma 110Locked
Postoperative Edema110Locked
Postoperative Recovery110Locked
Prostatitis: Bacterial110Locked
Tooth Extraction: Wisdom110Locked
Alzheimer's Disease39Locked
Colorectal Cancer38Locked
Inflammatory Bowel Diseases46Locked
Oxidative Stress36Locked
Rheumatoid Arthritis36Locked
Asthma35Locked
Cervical Cancer15Locked
Allergic Airway Diseases24Locked
Aluminum Toxicity 24Locked
Colitis24Locked
Colon Cancer24Locked
Diabetic Complications24Locked
Lipopolysaccharide-Induced Toxicity44Locked
Liver Damage24Locked
Neuropathic Pain24Locked
Tendon Injury24Locked
Chemotherapy-Induced Toxicity: Cisplatin23Locked
Liver Cirrhosis13Locked
Liver Fibrosis13Locked
Pancreatic Cancer23Locked
Skin Cancer33Locked
Atherosclerosis12Locked
Bisphenol Toxicity12Locked
Breastfeeding: Complications12Locked
Burns12Locked
Cadmium Poisoning 12Locked
Cancer Metastasis12Locked
Chemically-Induced Liver Damage12Locked
Diabetes Mellitus: Type 112Locked
Drug-Induced Toxicity: Indomethacin12Locked
Gastric Cancer22Locked
Gastrointestinal Inflammation12Locked
Kidney Damage: Chemically-Induced12Locked
Lactation Disorders12Locked
Lead Poisoning12Locked
Liver Cancer22Locked
Myocardial Infarction12Locked
Myocardial Ischemia12Locked
Non-Hodgkin Lymphoma12Locked
Nonalcoholic fatty liver disease (NAFLD)12Locked
Obesity12Locked
Prostate Cancer22Locked
Sciatic Nerve Crush Injury12Locked
Sperm Quality: Low12Locked
Arthritis11Locked
Benzo[a]pyrene-induced Toxicity 11Locked
Breast Cancer: Triple Negative 11Locked
Cholangiocarcinoma11Locked
Cholera11Locked
Digestive System Diseases11Locked
Escherichia coli Infections11Locked
Glioma11Locked
Gram-Positive Bacterial Infections11Locked
Immune Disorders11Locked
Influenza11Locked
Intestinal Permeability 11Locked
Leaky Gut Syndrome11Locked
Melanoma11Locked
Oral Cancer11Locked
Parkinson's Disease11Locked
Periodontal Diseases11Locked
Respiratory Diseases11Locked
Thrombophlebitis11Locked
60 Pharmacological Actions Researched for Bromelain
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View the Evidence:
115 Abstracts with Bromelain Research

[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Clin Med. 2023 Apr 18 ;12(8). Epub 2023 Apr 18. PMID: 37109265
Study Type : Human Study
Additional Links
Pharmacological Actions : Anti-Inflammatory Agents
[+]
Pubmed Data : J Altern Complement Med. 2019 Nov 1. Epub 2019 Nov 1. PMID: 31674795
Study Type : Human Study
Additional Links
Substances : Bromelain, Frankincense
Diseases : Osteoarthritis
Pharmacological Actions : Osteoprotective
[+]
Pubmed Data : Platelets. 2006 Feb;17(1):37-41. PMID: 16308185
Study Type : Human Study
Additional Links
Substances : Bromelain
Diseases : Thrombosis
Pharmacological Actions : Anti-Platelet
[+]
Pubmed Data : J Cancer Res Clin Oncol. 1988;114(5):507-8. PMID: 3182910
Study Type : Human Study
Additional Links
Substances : Bromelain, Pineapple
Diseases : Lung Cancer
Pharmacological Actions : Anti-metastatic
[+]
Pubmed Data : Clin Rheumatol. 2016 Oct ;35(10):2531-40. Epub 2016 Jul 28. PMID: 27470088
Study Type : Human Study
Additional Links
Substances : Bromelain
Problem Substances : Diclofenac
[+]
Pubmed Data : Eur Rev Med Pharmacol Sci. 2010 Sep;14(9):771-4. PMID: 21061836
Study Type : Human Study
Additional Links
Substances : Bromelain
Additional Keywords : Dental
[+]
Pubmed Data : In Vivo. 2005 Mar-Apr;19(2):417-21. PMID: 15796206
Study Type : Human Study
Additional Links
Substances : Bromelain
Diseases : Sinusitis
[+]
Pubmed Data : Pharmacol Res. 2007 Sep;56(3):254-60. Epub 2007 Jul 14. PMID: 16137711
Study Type : Human Study
Additional Links
Substances : Bromelain
[+]
Pubmed Data : Phytomedicine. 2002 Dec;9(8):681-6. PMID: 12587686
Study Type : Human Study
Additional Links
Substances : Bromelain
Pharmacological Actions : Analgesics
[+]
Pubmed Data : Br J Nutr. 2021 Jan 28 ;125(2):161-171. Epub 2020 Jul 14. PMID: 32660675
Study Type : Human Study
Additional Links
Substances : Anthocyanins, Bromelain
Pharmacological Actions : Antioxidants
[+]
Pubmed Data : Clin Oral Investig. 2019 May ;23(5):2443-2453. Epub 2018 Oct 11. PMID: 30311061
Study Type : Human Study
Additional Links
Substances : Bromelain, Flavonoids
Diseases : Dental Care
Pharmacological Actions : Analgesics
Additional Keywords : Phytotherapy, Plant Extracts
[+]
Pubmed Data : Med Oncol. 2017 Mar ;34(3):46. Epub 2017 Feb 15. PMID: 28205185
Study Type : Human Study
Additional Links
Pharmacological Actions : Chemoprotective Agents
[+]
Pubmed Data : Clin Exp Allergy. 2009 Jun;39(6):875-82. PMID: 19829282
Study Type : Human Study
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Arch Ital Urol Androl. 2016 Oct 5 ;88(3):177-182. Epub 2016 Oct 5. PMID: 27711089
Study Type : Human Study
Additional Links
Pharmacological Actions : Anti-Bacterial Agents
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Oral Health. 2023 May 13 ;23(1):286. Epub 2023 May 13. PMID: 37179311
Study Type : Human Study
Additional Links
Substances : Bromelain
Diseases : Periodontitis
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran Red Crescent Med J. 2016 Mar ;18(3):e21019. Epub 2016 Mar 1. PMID: 27247780
Study Type : Human Study
Additional Links
Substances : Bromelain, Pineapple
Pharmacological Actions : Analgesics
[+]
Pubmed Data : Phytother Res. 2016 Sep 6. Epub 2016 Sep 6. PMID: 27601419
Study Type : Human Study
Additional Links
Substances : Bromelain
Pharmacological Actions : Anti-Inflammatory Agents
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Turk J Biol. 2021 ;45(4):518-529. Epub 2021 Aug 30. PMID: 34803451
Study Type : Human Study
Additional Links
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Med Oncol. 2022 Jun 6 ;39(8):113. Epub 2022 Jun 6. PMID: 35666314
Study Type : Human Study
Additional Links
Substances : Bromelain, Frankincense
Diseases : Breast Cancer
Pharmacological Actions : Chemotherapeutic
[+]
Pubmed Data : J Biomed Nanotechnol. 2014 Dec ;10(12):3558-75. PMID: 26000370
Study Type : Human In Vitro
Additional Links
Substances : Bromelain
Pharmacological Actions : Antineoplastic Agents, Apoptotic
[+]
Pubmed Data : Curr Alzheimer Res. 2018 Jan 23. Epub 2018 Jan 23. PMID: 29359669
Study Type : Human In Vitro
Additional Links
Substances : Bromelain
Pharmacological Actions : Neuroprotective Agents
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Plants (Basel). 2021 Oct 23 ;10(11). Epub 2021 Oct 23. PMID: 34834636
Study Type : Animal Study, In Vitro Study
[+]
Pubmed Data : Tissue Cell. 2023 Jun ;82:102118. Epub 2023 May 27. PMID: 37269556
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Bromelain
Pharmacological Actions : Anti-Fibrotic, Antioxidants, Hepatoprotective
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Cancer Res. 2021 ;11(5):2252-2263. Epub 2021 May 15. PMID: 34094682
Study Type : Animal Study, In Vitro Study
Additional Links
Diseases : Colon Cancer
Pharmacological Actions : Chemosensitizer
[+]
Pubmed Data : Int J Biol Macromol. 2023 Feb 1 ;227:1119-1131. Epub 2022 Dec 1. PMID: 36462588
Study Type : Animal Study
Additional Links
Substances : Bromelain
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Aluminum
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Korean J Pain. 2020 Jan 1 ;33(1):13-22. PMID: 31888313
Study Type : Animal Study
Additional Links
Substances : Bromelain
Diseases : Neuropathic Pain
Pharmacological Actions : Antinoceceptive , Neuroprotective Agents
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2022 Dec 29 ;12(1). Epub 2022 Dec 29. PMID: 36670934
Study Type : Animal Study
Additional Links
Substances : Bromelain
Diseases : Atherosclerosis
[+]
Pubmed Data : J Pharm Pharmacol. 2022 Nov 25 ;74(12):1765-1775. PMID: 36227279
Study Type : Animal Study
[+]
Pubmed Data : J Surg Res. 2007 May 1;139(1):88-96. Epub 2007 Feb 8. PMID: 17292418
Study Type : Animal Study
Additional Links
Substances : Bromelain
Diseases : Liver Damage
Pharmacological Actions : Hepatoprotective
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Transl Res. 2021 ;13(12):13524-13539. Epub 2021 Dec 15. PMID: 35035694
Study Type : Animal Study, In Vitro Study
Additional Links
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]
Pubmed Data : J Med Food. 2011 Apr;14(4):348-52. Epub 2011 Jan 23. PMID: 21254908
Study Type : Animal Study
Additional Links
Substances : Bromelain, Pineapple
Diseases : Tendon Injury
[+]
Pubmed Data : Evid Based Complement Alternat Med. 2008 Mar;5(1):61-9. PMID: 18317550
Study Type : Animal Study
Additional Links
Substances : Bromelain
Diseases : Asthma
Pharmacological Actions : Anti-Asthmatic Agents
[+]
Pubmed Data : Cell Immunol. 2005 Sep;237(1):68-75. Epub 2005 Dec 6. PMID: 16337164
Study Type : Animal Study
Additional Links
Substances : Bromelain
[+]
Pubmed Data : Ann Nutr Metab. 2009;54(4):283-90. Epub 2009 Jul 27. PMID: 20623610
Study Type : Animal Study
Additional Links
Substances : Bromelain
Diseases : Tendon Injury
[+]
Pubmed Data : Altern Ther Health Med. 2012 Sep-Oct;18(5):9-17. PMID: 22894886
Study Type : Animal Study
[+]
Pubmed Data : Am J Physiol Heart Circ Physiol. 2008 Mar;294(3):H1365-70. Epub 2008 Jan 11. PMID: 18192224
Study Type : Animal Study
Additional Links
Substances : Bromelain
Pharmacological Actions : Apoptotic, Cardioprotective
[+]
Pubmed Data : Int Immunopharmacol. 2006 Dec 20;6(13-14):2038-46. Epub 2006 Sep 5. PMID: 17161360
Study Type : Animal Study
Additional Links
Substances : Bromelain
Pharmacological Actions : Interleukin-10 downregulation
[+]
Pubmed Data : Andrologia. 2022 Dec ;54(11):e14584. Epub 2022 Sep 6. PMID: 36068179
Study Type : Animal Study
Additional Links
Substances : Bromelain
Additional Keywords : Estrogen Receptor Beta
Problem Substances : Bisphenol A
[+]
Pubmed Data : Trop Anim Health Prod. 2009 Apr;41(4):493-8. Epub 2008 Jul 27. PMID: 18661260
Study Type : Animal Study
Additional Links
Substances : Bromelain
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2019 ;14(1):e0210274. Epub 2019 Jan 18. PMID: 30657763
Study Type : Animal Study
Additional Links
Substances : Bromelain
[+]
Pubmed Data : Int J Pharm. 2021 Feb 1 ;594:120176. Epub 2020 Dec 14. PMID: 33326825
Study Type : Animal Study
Additional Links
Substances : Bromelain
Pharmacological Actions : Anti-Inflammatory Agents
[+]
Pubmed Data : Int Immunopharmacol. 2023 Aug ;121:110446. Epub 2023 Jun 7. PMID: 37290321
Study Type : Animal Study
[+]
Pubmed Data : Naunyn Schmiedebergs Arch Pharmacol. 2019 Oct 26. Epub 2019 Oct 26. PMID: 31655851
Study Type : Animal Study
Additional Links
Substances : Bromelain
Pharmacological Actions : Antinoceceptive
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2022 ;2022:5342559. Epub 2022 Nov 21. PMID: 36452063
Study Type : Animal Study
Additional Links
Substances : Bromelain
Pharmacological Actions : Antioxidants, Hepatoprotective
Problem Substances : Aluminum
[+]
Pubmed Data : Nutr Cancer. 2019 Oct 8:1-11. Epub 2019 Oct 8. PMID: 31591915
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Bromelain, Pineapple
Pharmacological Actions : Antiproliferative , Apoptotic
[+]
Pubmed Data : Drug Chem Toxicol. 2021 Dec 13:1-8. Epub 2021 Dec 13. PMID: 34894956
Study Type : Animal Study
Additional Links
Substances : Bromelain
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2021 Jan 11 ;11(1):289. Epub 2021 Jan 11. PMID: 33432004
Study Type : Animal Study
[+]
Pubmed Data : Acta Biol Hung. 2015 Jun ;66(2):149-60. PMID: 26081271
Study Type : Animal Study
Additional Links
Substances : Bromelain
Diseases : Lead Poisoning
Problem Substances : Lead
[+]
Pubmed Data : Clin Immunol. 2008 Jul;128(1):66-74. Epub 2008 May 14. PMID: 18482869
Study Type : Animal Study
Additional Links
Substances : Bromelain
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
[+]
Pubmed Data : Inflamm Bowel Dis. 2010 Dec;16(12):2012-21. PMID: 20848493
Study Type : Animal Study
Additional Links
Substances : Bromelain
Diseases : Colitis, Colon Cancer
[+]
Pubmed Data : J Wound Care. 2022 Aug 1 ;31(Sup8):S4-S11. PMID: 36004940
Study Type : Animal Study
Additional Links
Substances : Bromelain
[+]
Pubmed Data : Probiotics Antimicrob Proteins. 2020 Nov 6. Epub 2020 Nov 6. PMID: 33156496
Study Type : Animal Study
Additional Links
Substances : Bromelain, Probiotics
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
[+]
Pubmed Data : Environ Toxicol Pharmacol. 2020 Nov ;80:103509. Epub 2020 Oct 1. PMID: 33010469
Study Type : Animal Study
Additional Links
Substances : Bromelain
Problem Substances : Aluminum
[+]
Pubmed Data : Neurotoxicology. 2022 05 ;90:19-34. Epub 2022 Feb 24. PMID: 35219781
Study Type : Animal Study
Additional Links
Substances : Bromelain
Pharmacological Actions : Neuroprotective Agents
[+]
Pubmed Data : Planta Med. 2007 Oct;73(13):1377-83. Epub 2007 Sep 24. PMID: 17893836
Study Type : Animal Study
[+]
Pubmed Data : Burns. 2020 Dec 10. Epub 2020 Dec 10. PMID: 33934907
Study Type : Animal Study
Additional Links
Substances : Bromelain
Diseases : Burns
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Arch Razi Inst. 2021 11 ;76(5):1427-1436. Epub 2021 Nov 30. PMID: 35355740
Study Type : Animal Study
Additional Links
Substances : Bromelain
Pharmacological Actions : Anti-Inflammatory Agents
Problem Substances : Cadmium
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2012 ;7(1):e30831. Epub 2012 Jan 24. PMID: 22292054
Study Type : Animal Study
Additional Links
Substances : Bromelain
Diseases : Obesity
Pharmacological Actions : Anti-Adipogenic, Apoptotic
Additional Keywords : Anti-Obesity Agents
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Integr Cancer Ther. 2020 Jan-Dec;19:1534735420950468. PMID: 32783540
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Bromelain
Diseases : Cancers: All
Pharmacological Actions : Radioprotective, Radiosensitizer
[+]
Pubmed Data : Life Sci. 2021 Nov 15 ;285:119982. Epub 2021 Sep 27. PMID: 34592232
Study Type : Animal Study
Additional Links
Substances : Bromelain
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2022 Jun 1 ;14(11). Epub 2022 Jun 1. PMID: 35684129
Study Type : Animal Study
Additional Links
Substances : Bromelain
Pharmacological Actions : Anticoagulants, Hepatoprotective
[+]
Pubmed Data : Int J Health Sci (Qassim). 2023 ;17(5):23-30. PMID: 37692988
Study Type : Animal Study
Additional Links
Substances : Bromelain, Papain
Pharmacological Actions : Gastroprotective
Problem Substances : Indomethacin
[+]
Pubmed Data : Front Immunol. 2017 ;8:1468. Epub 2017 Nov 10. PMID: 29176974
Study Type : Animal Study
Additional Links
Substances : Bromelain
Pharmacological Actions : Anti-Inflammatory Agents
[+]
Pubmed Data : Clin Immunol. 2005 Aug;116(2):135-42. PMID: 15936249
Study Type : Animal Study
Additional Links
Substances : Bromelain
[+]
Pubmed Data : J Wound Care. 2020 Sep 2 ;29(9):488-495. PMID: 32924815
Study Type : Animal Study
Additional Links
Substances : Bromelain
Pharmacological Actions : Anti-Inflammatory Agents
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Viruses. 2021 03 6 ;13(3). Epub 2021 Mar 6. PMID: 33800932
Study Type : In Vitro Study
Additional Links
Pharmacological Actions : Antiviral Agents
[+]
Pubmed Data : Cell Mol Life Sci. 2001 Aug ;58(9):1234-45. PMID: 11577981
Study Type : Review
Additional Links
Substances : Bromelain
Diseases : Thrombophlebitis
Additional Keywords : Phytotherapy
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Dent (Shiraz). 2022 Sep ;23(3):257-265. PMID: 36506883
Study Type : In Vitro Study
Additional Links
Substances : Bromelain
Pharmacological Actions : Chemoprotective Agents
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Medicina (Kaunas). 2021 Jun 8 ;57(6). Epub 2021 Jun 8. PMID: 34201357
Study Type : In Vitro Study
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Curr Issues Mol Biol. 2021 May 7 ;43(1):93-106. Epub 2021 May 7. PMID: 34067064
Study Type : In Vitro Study
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Immunopathol Pharmacol. 2021 Jan-Dec;35:20587384211034686. PMID: 34387509
Study Type : In Vitro Study
Additional Links
Substances : Bromelain
Pharmacological Actions : Anti-Inflammatory Agents
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Life (Basel). 2021 Apr 6 ;11(4). Epub 2021 Apr 6. PMID: 33917319
Study Type : Review
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Exp Clin Cancer Res. 2014 Nov 12 ;33:92. Epub 2014 Nov 12. PMID: 25425315
Study Type : In Vitro Study
Additional Links
Diseases : Gastric Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
Additional Keywords : Natural Substance Synergy
[+]
Pubmed Data : Environ Sci Pollut Res Int. 2021 Apr 23. Epub 2021 Apr 23. PMID: 33893581
Study Type : In Vitro Study
Additional Links
Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive
Additional Keywords : Natural Substance Synergy
Problem Substances : Benzo(a)pyrene
[+]
Pubmed Data : Bioorg Khim. 2008 May-Jun;34(3):409-15. PMID: 18672693
Study Type : In Vitro Study
Additional Links
Substances : Bromelain, Papain
Diseases : Influenza
Pharmacological Actions : Antiviral Agents
[+]
Pubmed Data : Int J Oncol. 2016 May ;48(5):2025-34. Epub 2016 Mar 1. PMID: 26935541
Study Type : In Vitro Study
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Anim Cells Syst (Seoul). 2018 ;22(5):334-340. Epub 2018 Aug 30. PMID: 30460115
Study Type : In Vitro Study
Additional Links
Substances : Bromelain
Pharmacological Actions : Antiproliferative , Cytotoxic
[+]
Pubmed Data : Arch Intern Med. 2005 Jan 24;165(2):200-6. PMID: 16950580
Study Type : In Vitro Study
Additional Links
Substances : Bromelain
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Int Oral Health. 2014 Sep ;6(5):96-8. PMID: 25395802
Study Type : In Vitro Study
Additional Links
Substances : Bromelain, Pineapple
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Plant Extracts
[+]
Pubmed Data : Int Immunopharmacol. 2009 Mar;9(3):340-6. Epub 2009 Jan 20. PMID: 19162239
Study Type : In Vitro Study
Additional Links
Substances : Bromelain
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
[+]
Pubmed Data : Mol Carcinog. 2011 Mar 22. Epub 2011 Mar 22. PMID: 21432909
Study Type : In Vitro Study
Additional Links
Substances : Bromelain
Diseases : Melanoma, Skin Cancer
Pharmacological Actions : Apoptotic, Cell cycle arrest, NF-kappaB Inhibitor
[+]
Pubmed Data : Cancer Lett. 2009 Sep 18;282(2):167-76. Epub 2009 Mar 31. PMID: 19339108
Study Type : In Vitro Study
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Med Signals Sens. 2019 Oct-Dec;9(4):267-273. Epub 2019 Oct 24. PMID: 31737556
Study Type : In Vitro Study
Additional Links
Substances : Bromelain
Pharmacological Actions : Anti-metastatic, Antiproliferative
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Chin Med. 2016 ;11:46. Epub 2016 Nov 15. PMID: 27891174
Study Type : In Vitro Study
Additional Links
Substances : Bromelain
Pharmacological Actions : Apoptotic, Chemosensitizer, Chemotherapeutic
[+]
Pubmed Data : J Med Food. 2012 Apr ;15(4):344-9. Epub 2011 Dec 22. PMID: 22191568
Study Type : In Vitro Study
Additional Links
Substances : Bromelain
Diseases : Breast Cancer
Pharmacological Actions : Apoptotic
Anti Therapeutic Actions : Nocebo Effect
[+]
Pubmed Data : Neoplasia. 2001 Nov-Dec;3(6):469-79. PMID: 11774029
Study Type : In Vitro Study
Additional Links
Substances : Bromelain
Diseases : Glioma
[+]
Pubmed Data : J Huazhong Univ Sci Technolog Med Sci. 2003;23(2):151-3. PMID: 18569070
Study Type : In Vitro Study
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : bioRxiv. 2020 Sep 16. Epub 2020 Sep 16. PMID: 32995771
Study Type : In Vitro Study
Additional Links
Substances : Bromelain
Pharmacological Actions : Antiviral Agents
[+]
Pubmed Data : Toxicol Appl Pharmacol. 2008 Jan 1;226(1):30-7. Epub 2007 Aug 23. PMID: 17889918
Study Type : In Vitro Study
[+]
Pubmed Data : Clin Immunol. 2008 Mar;126(3):345-52. Epub 2007 Dec 21. PMID: 18160345
Study Type : In Vitro Study
Additional Links
Substances : Bromelain
[+]
Pubmed Data : Eur J Med Res. 2005 Aug 17;10(8):325-31. PMID: 16131473
Study Type : In Vitro Study
Additional Links
Substances : Bromelain
Diseases : Immune Disorders
Pharmacological Actions : Antiproliferative , Immunostimulatory
[+]
Pubmed Data : In Vivo. 1999 Jan-Feb;13(1):7-12. PMID: 10218125
Study Type : In Vitro Study
Additional Links
Substances : Bromelain
Diseases : Thrombosis
Pharmacological Actions : Anti-Platelet, Thrombolytic
[+]
Pubmed Data : Clin Nutr ESPEN. 2023 Jun ;55:116-127. Epub 2023 Mar 2. PMID: 37202035
Study Type : Review
Additional Links
Substances : Bromelain
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Integr Cancer Ther. 2019 Jan-Dec;18:1534735419880258. PMID: 31752555
Study Type : In Vitro Study
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Galen Med J. 2020 ;9:e1749. Epub 2020 Aug 29. PMID: 34466585
Study Type : In Vitro Study
Additional Links
Substances : Bromelain
Diseases : Prostate Cancer
Pharmacological Actions : Apoptotic, Chemosensitizer
[+]
Pubmed Data : Food Funct. 2023 Aug 31. Epub 2023 Aug 31. PMID: 37650738
Study Type : Review
Additional Links
Substances : Bromelain
Pharmacological Actions : Anti-Inflammatory Agents
[+]
Pubmed Data : Niger J Physiol Sci. 2020 06 30 ;35(1):10-19. Epub 2020 Jun 30. PMID: 33084621
Study Type : Review
Additional Links
Substances : Bromelain
Pharmacological Actions : Anti-Inflammatory Agents, Anticoagulants
Additional Keywords : Phytotherapy, Plant Extracts
[+]
Pubmed Data : J Agric Food Chem. 2006 Mar 22;54(6):2193-8. PMID: 16536595
Study Type : In Vitro Study
[+]
Pubmed Data : Appl Biochem Biotechnol. 2021 Mar 18. Epub 2021 Mar 18. PMID: 33735410
Study Type : In Vitro Study
Additional Links
Substances : Bromelain
Diseases : Liver Cancer
Pharmacological Actions : Apoptotic
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Transl Res. 2020 ;12(11):7404-7419. Epub 2020 Nov 15. PMID: 33312377
Study Type : In Vitro Study
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Med Signals Sens. 2019 Jan-Mar;9(1):68-74. PMID: 30967992
Study Type : In Vitro Study
Additional Links
Substances : Bromelain
Diseases : Breast Cancer
Pharmacological Actions : Antiproliferative , Radiosensitizer
[+]
Pubmed Data : Skin Therapy Lett. 2000 ;5(4):3-5. PMID: 10785407
Study Type : Review
Additional Links
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Phytotherapy, Plant Extracts
[+]
Pubmed Data : Int Immunopharmacol. 2017 Sep ;50:291-304. PMID: 28734166
Study Type : Review
Additional Links
Diseases : Cancers: All
Pharmacological Actions : Antineoplastic Agents, Immunomodulatory
[+]
Pubmed Data : Mol Biol Rep. 2021 Dec ;48(12):7711-7717. Epub 2021 Oct 13. PMID: 34643923
Study Type : In Vitro Study
Additional Links
Substances : Bromelain
Pharmacological Actions : Neuroprotective Agents
[+]
Pubmed Data : Int J Food Microbiol. 2016 Jan 4 ;216:121-6. Epub 2015 Oct 8. PMID: 26476327
Study Type : In Vitro Study
Additional Links
Substances : Bromelain, Papain
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Natural Substance Synergy
[+]
Pubmed Data : Biofactors. 2010 Sep 16. Epub 2010 Sep 16. PMID: 20848558
Study Type : In Vitro Study
Additional Links
Substances : Bromelain, Pineapple
Diseases : Breast Cancer
Pharmacological Actions : Apoptotic, Autophagy Up-regulation
Additional Keywords : Autophagy
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Integr Cancer Ther. 2021 Jan-Dec;20:15347354211060369. PMID: 34825602
Study Type : In Vitro Study
Additional Links
Substances : Bromelain
Diseases : Cancers: All
Pharmacological Actions : NF-kappaB Inhibitor, Radiosensitizer
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2017 Dec 21 ;7(1):18031. Epub 2017 Dec 21. PMID: 29269741
Study Type : In Vitro Study
Additional Links
Substances : Bromelain
Pharmacological Actions : Antimicrobial, Antioxidants
[+]
Pubmed Data : Cancer Lett. 2010 Apr 28;290(2):148-56. Epub 2009 Aug 22. PMID: 19700238
Study Type : Review
Additional Links
Substances : Bromelain
Diseases : Cancers: All
Pharmacological Actions : Antineoplastic Agents
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Med Ther. 2021 Oct 14 ;21(1):261. Epub 2021 Oct 14. PMID: 34649531
Study Type : In Vitro Study
Additional Links
Substances : Bromelain, Curcumin
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Plant Extracts
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Metabol Open. 2020 Dec ;8:100066. Epub 2020 Nov 13. PMID: 33205039
Study Type : In Vitro Study
Additional Links
Substances : Bromelain, Curcumin
Pharmacological Actions : Antiviral Agents, Immunostimulatory
Additional Keywords : Natural Substance Synergy
[+]
Pubmed Data : J Craniofac Surg. 2019 Jun ;30(4):1064-1067. PMID: 30358745
Study Type : In Vitro Study
Additional Links
Substances : Bromelain
Diseases : Wound Healing
Pharmacological Actions : Anti-Inflammatory Agents
Problem Substances : Dexamethasone
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Rep. 2016 Sep ;5(3):283-288. Epub 2016 Jul 18. PMID: 27602208
Study Type : Review
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Sci Nutr. 2019 May ;7(5):1656-1667. Epub 2019 Apr 1. PMID: 31139378
Study Type : In Vitro Study
Additional Links
Substances : Bromelain
Diseases : Oral Cancer
Pharmacological Actions : Anticarcinogenic Agents, Antiproliferative
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2021 ;12:717757. Epub 2021 Aug 20. PMID: 34489706
Study Type : In Vitro Study
Additional Links
Substances : Bromelain
Pharmacological Actions : Antiviral Agents

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Enjoyed the world over as something of an icon of the tropical experience, the pineapple was used in indigenous medicine for a wide range of ailments; uses that are only now being confirmed by modern scientific methods.
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Sinus infections are the fifth most common reason antibiotics are prescribed for adults. Unfortunately, they are of no help for most sinus infections – this according to a new study published in the Journal of the American Medical Association (JAMA)
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Enzyme preparations are one of nature’s most powerful therapeutic agents - particularly, the proteolytic enzyme serrapeptase or the “silk worm” enzyme
A new study found that the pineapple enzyme bromelain reduces pain as effectively as the popular drug ibuprofen after dental surgery
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