Results for neohesperidin

Antioxidant and pancreatic lipase inhibitory effects of flavonoids from different citrus peel extracts.

Article Published Date : Apr 10, 2020
Study Type : In Vitro Study
Additional Links
Substances : Citrus naringin : CK(440) : AC(245), Citrus Peel : CK(159) : AC(62), Hesperidin : CK(950) : AC(358), neohesperidin
Diseases : Metabolic Syndrome X : CK(3063) : AC(541), Obesity : CK(10447) : AC(2590), Oxidative Stress : CK(14393) : AC(5534)
Pharmacological Actions : Antioxidants : CK(34009) : AC(14223), Enzyme Inhibitors: Pancreatic Lipase : CK(54) : AC(25)

Citrus flavonoids as promising phytochemicals targeting diabetes and related complications.

Article Published Date : Sep 22, 2020
Study Type : Review
Additional Links
Substances : Citrus naringin : CK(440) : AC(245), Diosgenin : CK(245) : AC(146), Flavonoids : CK(4695) : AC(2173), Fruit: All : CK(9379) : AC(2226), Hesperidin : CK(950) : AC(358), Naringenin : CK(704) : AC(394), neohesperidin, Nobiletin : CK(379) : AC(226), Quercetin : CK(1864) : AC(847), Rutin : CK(461) : AC(222), Tangeretin : CK(163) : AC(93), Xanthohumol : CK(279) : AC(187)
Diseases : Diabetic Complications : CK(4548) : AC(1551)
Pharmacological Actions : Antioxidants : CK(34009) : AC(14223), Hepatoprotective : CK(8852) : AC(3772), Hypoglycemic Agents : CK(8653) : AC(2023), Hypolipidemic : CK(8825) : AC(1989), Renoprotective : CK(4475) : AC(1938)

Hesperidin promotes programmed cell death by downregulation of nongenomic estrogen receptor signalling pathway in endometrial cancer cells.

Article Published Date : Apr 13, 2018
Study Type : In Vitro Study
Additional Links
Substances : neohesperidin
Diseases : Endometrial Cancer : CK(515) : AC(126)
Pharmacological Actions : Apoptotic : CK(9480) : AC(7298)

Neohesperidin alleviates the inhibitory effect of bisphenol A on the myogenic differentiation of umbilical cord mesenchymal stem cells.

Article Published Date : Sep 14, 2024
Study Type : In Vitro Study
Additional Links
Substances : neohesperidin
Diseases : Bisphenol Toxicity : CK(4363) : AC(1306)
Problem Substances : Bisphenol A : CK(4552) : AC(1317)

Neohesperidin attenuates DSS-induced ulcerative colitis by inhibiting inflammation.

Article Published Date : Sep 17, 2024
Study Type : In Vitro Study
Additional Links
Substances : neohesperidin
Diseases : Inflammation : CK(15586) : AC(5304), Ulcerative Colitis : CK(1392) : AC(437)
Pharmacological Actions : Anti-Inflammatory Agents : CK(38459) : AC(15387), Gastroprotective : CK(1655) : AC(687), NF-kappaB Inhibitor : CK(5826) : AC(3390)

Neohesperidin exerts antidepressant-like effect via the mechanistic target of rapamycin complex 1 in the medial prefrontal cortex in male mice.

Article Published Date : Sep 30, 2024
Study Type : Animal Study
Additional Links
Substances : neohesperidin
Diseases : Depression : CK(9406) : AC(1726)
Pharmacological Actions : Antidepressive Agents : CK(7847) : AC(1450)

Neohesperidin exerts lipid-regulating effects in vitro and in vivo.

Article Published Date : Dec 31, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : neohesperidin
Diseases : Dyslipidemias : CK(1620) : AC(326)
Pharmacological Actions : Hypolipidemic : CK(8825) : AC(1989)

Neohesperidin inhibits cardiac remodeling induced by Ang II in vivo and in vitro.

Article Published Date : Jun 08, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : neohesperidin
Diseases : Cardiac Hypertrophy : CK(246) : AC(134)
Pharmacological Actions : Anti-Inflammatory Agents : CK(38459) : AC(15387), Antioxidants : CK(34009) : AC(14223), Cardioprotective : CK(9278) : AC(2896)

Neohesperidin inhibits TGF-β1/Smad3 signaling and alleviates bleomycin-induced pulmonary fibrosis in mice.

Article Published Date : Nov 30, 2019
Study Type : Animal Study
Additional Links
Substances : neohesperidin
Diseases : Pulmonary Fibrosis: Bleomycin-Induced : CK(171) : AC(90)
Pharmacological Actions : Anti-Fibrotic : CK(2165) : AC(1027), Chemoprotective Agents : CK(4209) : AC(1597), Transforming growth factor beta (TGF-β) inhibitor : CK(573) : AC(287)

Neohesperidin prevents Aβ25-35-induced apoptosis in primary cultured hippocampal neurons.

Article Published Date : Jun 29, 2018
Study Type : In Vitro Study
Additional Links
Substances : neohesperidin
Diseases : Alzheimer's Disease : CK(5252) : AC(2165)
Pharmacological Actions : Neuroprotective Agents : CK(19672) : AC(7790)

Neohesperidin prevents colorectal tumorigenesis by altering the gut microbiota.

Article Published Date : Jan 09, 2019
Study Type : Transgenic Animal Study
Additional Links
Substances : neohesperidin
Diseases : Colorectal Cancer : CK(4830) : AC(2248)
Pharmacological Actions : Chemopreventive : CK(6496) : AC(2135), Gastrointestinal Agents : CK(7505) : AC(2225)

Neohesperidin suppresses IgE-mediated anaphylactic reactions.

Article Published Date : Jul 31, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : neohesperidin
Diseases : Allergies : CK(1736) : AC(374), Anaphylactic Reaction : CK(18) : AC(8), IgE-Mediated Hypersensitivity : CK(82) : AC(24)
Pharmacological Actions : Immunomodulatory : CK(6374) : AC(2324)

The anti-aging potential of neohesperidin and its synergistic effects with other citrus flavonoids.

Article Published Date : Nov 12, 2019
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids : CK(4695) : AC(2173), neohesperidin
Diseases : Aging : CK(6110) : AC(1473), Oxidative Stress : CK(14393) : AC(5534)
Pharmacological Actions : Antioxidants : CK(34009) : AC(14223)
Additional Keywords : Natural Substance Synergy : CK(1374) : AC(659)

The results suggest neohesperidin possesses therapeutic potential as a natural anti-catabolic treatment in osteoporosis.

Article Published Date : Jan 04, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : neohesperidin
Diseases : Osteoporosis : CK(2754) : AC(745)
Pharmacological Actions : Anti-Apoptotic : CK(5413) : AC(3081), NF-kappaB Inhibitor : CK(5826) : AC(3390)
Additional Keywords : Ovariectomy-Induced Changes : CK(381) : AC(168)

Therapeutic effect of neohesperidin on TNF-α-stimulated human rheumatoid arthritis fibroblast-like synoviocytes.

Article Published Date : Sep 30, 2021
Study Type : In Vitro Study
Additional Links
Substances : neohesperidin
Diseases : Rheumatoid Arthritis : CK(2286) : AC(552)
Pharmacological Actions : Anti-Inflammatory Agents : CK(38459) : AC(15387), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(11372) : AC(4686)

Therapeutic effects of citrus flavonoids neohesperidin, hesperidin and its aglycone, hesperetin on bone health.

Article Published Date : Jan 22, 2022
Study Type : Review
Additional Links
Substances : Flavonoids : CK(4695) : AC(2173), Hesperidin : CK(950) : AC(358), neohesperidin
Diseases : Osteoarthritis : CK(2185) : AC(609), Osteoporosis : CK(2754) : AC(745), Periodontitis : CK(1081) : AC(266)
Pharmacological Actions : Anti-Inflammatory Agents : CK(38459) : AC(15387)

This study identified three lead compounds hesperidin, narirutin, and neohesperidin suitable for multitarget SARS-CoV-2 inhibition.

Article Published Date : Oct 27, 2022
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids : CK(4695) : AC(2173), Hesperidin : CK(950) : AC(358), neohesperidin
Diseases : Coronavirus Infection : CK(3297) : AC(986)
Pharmacological Actions : Antiviral Agents : CK(3077) : AC(1693)
Additional Keywords : SARS-CoV-2 Spike Protein

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