Results for neohesperidin

Antioxidant and pancreatic lipase inhibitory effects of flavonoids from different citrus peel extracts.

Article Published Date : Apr 10, 2020
Study Type : In Vitro Study
Additional Links
Substances : Citrus naringin : CK(452) : AC(252), Citrus Peel : CK(159) : AC(62), Hesperidin : CK(1002) : AC(381), neohesperidin
Diseases : Metabolic Syndrome X : CK(3120) : AC(552), Obesity : CK(11439) : AC(2766), Oxidative Stress : CK(15904) : AC(6199)
Pharmacological Actions : Antioxidants : CK(36423) : AC(15247), Enzyme Inhibitors: Pancreatic Lipase : CK(54) : AC(25)

Citrus flavonoids as promising phytochemicals targeting diabetes and related complications.

Article Published Date : Sep 22, 2020
Study Type : Review
Additional Links
Substances : Citrus naringin : CK(452) : AC(252), Diosgenin : CK(245) : AC(146), Flavonoids : CK(4918) : AC(2288), Fruit: All : CK(9437) : AC(2255), Hesperidin : CK(1002) : AC(381), Naringenin : CK(744) : AC(409), neohesperidin, Nobiletin : CK(401) : AC(243), Quercetin : CK(1895) : AC(870), Rutin : CK(468) : AC(225), Tangeretin : CK(163) : AC(93), Xanthohumol : CK(301) : AC(201)
Diseases : Diabetic Complications : CK(4866) : AC(1659)
Pharmacological Actions : Antioxidants : CK(36423) : AC(15247), Hepatoprotective : CK(9512) : AC(4029), Hypoglycemic Agents : CK(9701) : AC(2160), Hypolipidemic : CK(9565) : AC(2130), Renoprotective : CK(4799) : AC(2079)

Hesperidin promotes programmed cell death by downregulation of nongenomic estrogen receptor signalling pathway in endometrial cancer cells.

Article Published Date : Apr 13, 2018
Study Type : In Vitro Study
Additional Links
Substances : neohesperidin
Diseases : Endometrial Cancer : CK(541) : AC(133)
Pharmacological Actions : Apoptotic : CK(9975) : AC(7707)

Mechanistic and metabolic exploration of neohesperidin against lung cancer cell lines.

Article Published Date : May 31, 2025
Study Type : In Vitro Study
Additional Links
Substances : neohesperidin
Diseases : Lung Cancer : CK(3151) : AC(1476)
Pharmacological Actions : Antineoplastic Agents : CK(2349) : AC(1561), Apoptotic : CK(9975) : AC(7707)

Neohesperidin alleviates the inhibitory effect of bisphenol A on the myogenic differentiation of umbilical cord mesenchymal stem cells.

Article Published Date : Sep 14, 2024
Study Type : In Vitro Study
Additional Links
Substances : neohesperidin
Diseases : Bisphenol Toxicity : CK(4436) : AC(1340)
Problem Substances : Bisphenol A : CK(4590) : AC(1334)

Neohesperidin attenuates DSS-induced ulcerative colitis by inhibiting inflammation.

Article Published Date : Sep 17, 2024
Study Type : In Vitro Study
Additional Links
Substances : neohesperidin
Diseases : Inflammation : CK(16872) : AC(5752), Ulcerative Colitis : CK(1551) : AC(499)
Pharmacological Actions : Anti-Inflammatory Agents : CK(42098) : AC(16773), Gastroprotective : CK(1771) : AC(738), NF-kappaB Inhibitor : CK(6268) : AC(3628)

Neohesperidin exerts antidepressant-like effect via the mechanistic target of rapamycin complex 1 in the medial prefrontal cortex in male mice.

Article Published Date : Sep 30, 2024
Study Type : Animal Study
Additional Links
Substances : neohesperidin
Diseases : Depression : CK(9970) : AC(1846)
Pharmacological Actions : Antidepressive Agents : CK(8283) : AC(1549)

Neohesperidin exerts lipid-regulating effects in vitro and in vivo.

Article Published Date : Dec 31, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : neohesperidin
Diseases : Dyslipidemias : CK(1712) : AC(343)
Pharmacological Actions : Hypolipidemic : CK(9565) : AC(2130)

Neohesperidin improves depressive-like behavior.

Article Published Date : Jan 02, 2025
Study Type : Animal Study
Additional Links
Substances : neohesperidin
Diseases : Depression : CK(9968) : AC(1845)
Pharmacological Actions : Antidepressive Agents : CK(8281) : AC(1548)

Neohesperidin inhibits cardiac remodeling induced by Ang II in vivo and in vitro.

Article Published Date : Jun 08, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : neohesperidin
Diseases : Cardiac Hypertrophy : CK(249) : AC(136)
Pharmacological Actions : Anti-Inflammatory Agents : CK(42098) : AC(16773), Antioxidants : CK(36423) : AC(15247), Cardioprotective : CK(9787) : AC(3070)

Neohesperidin inhibits TGF-β1/Smad3 signaling and alleviates bleomycin-induced pulmonary fibrosis in mice.

Article Published Date : Nov 30, 2019
Study Type : Animal Study
Additional Links
Substances : neohesperidin
Diseases : Pulmonary Fibrosis: Bleomycin-Induced : CK(187) : AC(98)
Pharmacological Actions : Anti-Fibrotic : CK(2379) : AC(1127), Chemoprotective Agents : CK(4470) : AC(1702), Transforming growth factor beta (TGF-β) inhibitor : CK(614) : AC(312)

Neohesperidin mitigates high-fat-diet-induced colitis.

Article Published Date : Jan 09, 2025
Study Type : Animal Study
Additional Links
Substances : neohesperidin
Diseases : Colitis : CK(1646) : AC(782)
Pharmacological Actions : Anti-Inflammatory Agents : CK(42098) : AC(16773), Gastrointestinal Agents : CK(8174) : AC(2463)

Neohesperidin prevents Aβ25-35-induced apoptosis in primary cultured hippocampal neurons.

Article Published Date : Jun 29, 2018
Study Type : In Vitro Study
Additional Links
Substances : neohesperidin
Diseases : Alzheimer's Disease : CK(5568) : AC(2321)
Pharmacological Actions : Neuroprotective Agents : CK(21280) : AC(8422)

Neohesperidin prevents colorectal tumorigenesis by altering the gut microbiota.

Article Published Date : Jan 09, 2019
Study Type : Transgenic Animal Study
Additional Links
Substances : neohesperidin
Diseases : Colorectal Cancer : CK(5022) : AC(2361)
Pharmacological Actions : Chemopreventive : CK(6654) : AC(2205), Gastrointestinal Agents : CK(8174) : AC(2463)

Neohesperidin protects against colitis-associated colorectal cancer.

Article Published Date : Jan 31, 2025
Study Type : Animal Study
Additional Links
Substances : neohesperidin
Diseases : Colitis : CK(1646) : AC(782), Colorectal Cancer : CK(5022) : AC(2361)
Pharmacological Actions : Anti-Inflammatory Agents : CK(42098) : AC(16773), Apoptotic : CK(9975) : AC(7707), Chemopreventive : CK(6654) : AC(2205), Cyclooxygenase 2 Inhibitors : CK(2324) : AC(1362), Interleukin-1 beta downregulation : CK(6417) : AC(3113), Interleukin-6 Downregulation : CK(9835) : AC(3814), NF-kappaB Inhibitor : CK(6268) : AC(3628), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(12268) : AC(5036)

Neohesperidin suppresses IgE-mediated anaphylactic reactions.

Article Published Date : Jul 31, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : neohesperidin
Diseases : Allergies : CK(2024) : AC(413), Anaphylactic Reaction : CK(18) : AC(8), IgE-Mediated Hypersensitivity : CK(82) : AC(24)
Pharmacological Actions : Immunomodulatory : CK(6904) : AC(2478)

The anti-aging potential of neohesperidin and its synergistic effects with other citrus flavonoids.

Article Published Date : Nov 12, 2019
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids : CK(4918) : AC(2288), neohesperidin
Diseases : Aging : CK(6493) : AC(1582), Oxidative Stress : CK(15904) : AC(6199)
Pharmacological Actions : Antioxidants : CK(36423) : AC(15247)
Additional Keywords : Natural Substance Synergy : CK(1452) : AC(696)

The results suggest neohesperidin possesses therapeutic potential as a natural anti-catabolic treatment in osteoporosis.

Article Published Date : Jan 04, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : neohesperidin
Diseases : Osteoporosis : CK(2872) : AC(797)
Pharmacological Actions : Anti-Apoptotic : CK(5974) : AC(3378), NF-kappaB Inhibitor : CK(6268) : AC(3628)
Additional Keywords : Ovariectomy-Induced Changes : CK(422) : AC(183)

Therapeutic effect of neohesperidin on TNF-α-stimulated human rheumatoid arthritis fibroblast-like synoviocytes.

Article Published Date : Sep 30, 2021
Study Type : In Vitro Study
Additional Links
Substances : neohesperidin
Diseases : Rheumatoid Arthritis : CK(2487) : AC(594)
Pharmacological Actions : Anti-Inflammatory Agents : CK(42098) : AC(16773), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(12268) : AC(5036)

Therapeutic effects of citrus flavonoids neohesperidin, hesperidin and its aglycone, hesperetin on bone health.

Article Published Date : Jan 22, 2022
Study Type : Review
Additional Links
Substances : Flavonoids : CK(4918) : AC(2288), Hesperidin : CK(1002) : AC(381), neohesperidin
Diseases : Osteoarthritis : CK(2314) : AC(663), Osteoporosis : CK(2872) : AC(797), Periodontitis : CK(1377) : AC(325)
Pharmacological Actions : Anti-Inflammatory Agents : CK(42098) : AC(16773)

This study identified three lead compounds hesperidin, narirutin, and neohesperidin suitable for multitarget SARS-CoV-2 inhibition.

Article Published Date : Oct 27, 2022
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids : CK(4918) : AC(2288), Hesperidin : CK(1002) : AC(381), neohesperidin
Diseases : Coronavirus Infection : CK(3250) : AC(986)
Pharmacological Actions : Antiviral Agents : CK(3162) : AC(1740)
Additional Keywords : SARS-CoV-2 Spike Protein

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