Results for neohesperidin

Antioxidant and pancreatic lipase inhibitory effects of flavonoids from different citrus peel extracts.

Article Published Date : Apr 10, 2020
Study Type : In Vitro Study
Additional Links
Substances : Citrus naringin : CK(440) : AC(245), Citrus Peel : CK(159) : AC(62), Hesperidin : CK(953) : AC(360), neohesperidin
Diseases : Metabolic Syndrome X : CK(3095) : AC(546), Obesity : CK(11004) : AC(2672), Oxidative Stress : CK(14758) : AC(5716)
Pharmacological Actions : Antioxidants : CK(34551) : AC(14499), Enzyme Inhibitors: Pancreatic Lipase : CK(54) : AC(25)

Citrus flavonoids as promising phytochemicals targeting diabetes and related complications.

Article Published Date : Sep 22, 2020
Study Type : Review
Additional Links
Substances : Citrus naringin : CK(440) : AC(245), Diosgenin : CK(245) : AC(146), Flavonoids : CK(4698) : AC(2176), Fruit: All : CK(9437) : AC(2238), Hesperidin : CK(953) : AC(360), Naringenin : CK(704) : AC(394), neohesperidin, Nobiletin : CK(379) : AC(226), Quercetin : CK(1876) : AC(855), Rutin : CK(463) : AC(223), Tangeretin : CK(163) : AC(93), Xanthohumol : CK(279) : AC(187)
Diseases : Diabetic Complications : CK(4678) : AC(1606)
Pharmacological Actions : Antioxidants : CK(34551) : AC(14499), Hepatoprotective : CK(8989) : AC(3831), Hypoglycemic Agents : CK(9221) : AC(2076), Hypolipidemic : CK(9173) : AC(2038), Renoprotective : CK(4544) : AC(1971)

Hesperidin promotes programmed cell death by downregulation of nongenomic estrogen receptor signalling pathway in endometrial cancer cells.

Article Published Date : Apr 13, 2018
Study Type : In Vitro Study
Additional Links
Substances : neohesperidin
Diseases : Endometrial Cancer : CK(528) : AC(129)
Pharmacological Actions : Apoptotic : CK(9585) : AC(7379)

Neohesperidin alleviates the inhibitory effect of bisphenol A on the myogenic differentiation of umbilical cord mesenchymal stem cells.

Article Published Date : Sep 14, 2024
Study Type : In Vitro Study
Additional Links
Substances : neohesperidin
Diseases : Bisphenol Toxicity : CK(4416) : AC(1329)
Problem Substances : Bisphenol A : CK(4570) : AC(1323)

Neohesperidin attenuates DSS-induced ulcerative colitis by inhibiting inflammation.

Article Published Date : Sep 17, 2024
Study Type : In Vitro Study
Additional Links
Substances : neohesperidin
Diseases : Inflammation : CK(16094) : AC(5496), Ulcerative Colitis : CK(1411) : AC(447)
Pharmacological Actions : Anti-Inflammatory Agents : CK(39737) : AC(15858), Gastroprotective : CK(1692) : AC(701), NF-kappaB Inhibitor : CK(5952) : AC(3464)

Neohesperidin exerts antidepressant-like effect via the mechanistic target of rapamycin complex 1 in the medial prefrontal cortex in male mice.

Article Published Date : Sep 30, 2024
Study Type : Animal Study
Additional Links
Substances : neohesperidin
Diseases : Depression : CK(9514) : AC(1751)
Pharmacological Actions : Antidepressive Agents : CK(7908) : AC(1466)

Neohesperidin exerts lipid-regulating effects in vitro and in vivo.

Article Published Date : Dec 31, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : neohesperidin
Diseases : Dyslipidemias : CK(1626) : AC(329)
Pharmacological Actions : Hypolipidemic : CK(9173) : AC(2038)

Neohesperidin inhibits cardiac remodeling induced by Ang II in vivo and in vitro.

Article Published Date : Jun 08, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : neohesperidin
Diseases : Cardiac Hypertrophy : CK(248) : AC(135)
Pharmacological Actions : Anti-Inflammatory Agents : CK(39737) : AC(15858), Antioxidants : CK(34551) : AC(14499), Cardioprotective : CK(9504) : AC(2963)

Neohesperidin inhibits TGF-β1/Smad3 signaling and alleviates bleomycin-induced pulmonary fibrosis in mice.

Article Published Date : Nov 30, 2019
Study Type : Animal Study
Additional Links
Substances : neohesperidin
Diseases : Pulmonary Fibrosis: Bleomycin-Induced : CK(173) : AC(91)
Pharmacological Actions : Anti-Fibrotic : CK(2209) : AC(1052), Chemoprotective Agents : CK(4278) : AC(1621), Transforming growth factor beta (TGF-β) inhibitor : CK(580) : AC(292)

Neohesperidin prevents Aβ25-35-induced apoptosis in primary cultured hippocampal neurons.

Article Published Date : Jun 29, 2018
Study Type : In Vitro Study
Additional Links
Substances : neohesperidin
Diseases : Alzheimer's Disease : CK(5355) : AC(2210)
Pharmacological Actions : Neuroprotective Agents : CK(20061) : AC(7949)

Neohesperidin prevents colorectal tumorigenesis by altering the gut microbiota.

Article Published Date : Jan 09, 2019
Study Type : Transgenic Animal Study
Additional Links
Substances : neohesperidin
Diseases : Colorectal Cancer : CK(4889) : AC(2276)
Pharmacological Actions : Chemopreventive : CK(6580) : AC(2166), Gastrointestinal Agents : CK(7657) : AC(2274)

Neohesperidin suppresses IgE-mediated anaphylactic reactions.

Article Published Date : Jul 31, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : neohesperidin
Diseases : Allergies : CK(2000) : AC(406), Anaphylactic Reaction : CK(18) : AC(8), IgE-Mediated Hypersensitivity : CK(82) : AC(24)
Pharmacological Actions : Immunomodulatory : CK(6531) : AC(2360)

The anti-aging potential of neohesperidin and its synergistic effects with other citrus flavonoids.

Article Published Date : Nov 12, 2019
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids : CK(4698) : AC(2176), neohesperidin
Diseases : Aging : CK(6221) : AC(1510), Oxidative Stress : CK(14758) : AC(5716)
Pharmacological Actions : Antioxidants : CK(34551) : AC(14499)
Additional Keywords : Natural Substance Synergy : CK(1400) : AC(669)

The results suggest neohesperidin possesses therapeutic potential as a natural anti-catabolic treatment in osteoporosis.

Article Published Date : Jan 04, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : neohesperidin
Diseases : Osteoporosis : CK(2786) : AC(758)
Pharmacological Actions : Anti-Apoptotic : CK(5568) : AC(3160), NF-kappaB Inhibitor : CK(5952) : AC(3464)
Additional Keywords : Ovariectomy-Induced Changes : CK(395) : AC(175)

Therapeutic effect of neohesperidin on TNF-α-stimulated human rheumatoid arthritis fibroblast-like synoviocytes.

Article Published Date : Sep 30, 2021
Study Type : In Vitro Study
Additional Links
Substances : neohesperidin
Diseases : Rheumatoid Arthritis : CK(2322) : AC(562)
Pharmacological Actions : Anti-Inflammatory Agents : CK(39737) : AC(15858), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(11697) : AC(4806)

Therapeutic effects of citrus flavonoids neohesperidin, hesperidin and its aglycone, hesperetin on bone health.

Article Published Date : Jan 22, 2022
Study Type : Review
Additional Links
Substances : Flavonoids : CK(4698) : AC(2176), Hesperidin : CK(953) : AC(360), neohesperidin
Diseases : Osteoarthritis : CK(2225) : AC(627), Osteoporosis : CK(2786) : AC(758), Periodontitis : CK(1328) : AC(311)
Pharmacological Actions : Anti-Inflammatory Agents : CK(39737) : AC(15858)

This study identified three lead compounds hesperidin, narirutin, and neohesperidin suitable for multitarget SARS-CoV-2 inhibition.

Article Published Date : Oct 27, 2022
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids : CK(4698) : AC(2176), Hesperidin : CK(953) : AC(360), neohesperidin
Diseases : Coronavirus Infection : CK(3250) : AC(986)
Pharmacological Actions : Antiviral Agents : CK(3095) : AC(1702)
Additional Keywords : SARS-CoV-2 Spike Protein

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