Results for Acetaminophen

Anti-inflammatory and antioxidant effects of Apium graveolens L. extracts mitigate against fatal acetaminophen-induced acute liver toxicity.

Article Published Date : Jul 25, 2020
Study Type : Animal Study
Additional Links
Substances : Celery : CK(207) : AC(81)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355), Liver Damage: Drug-Induced : CK(635) : AC(277)
Pharmacological Actions : Anti-Inflammatory Agents : CK(38674) : AC(15430), Antioxidants : CK(34012) : AC(14225), Hepatoprotective : CK(8852) : AC(3772)
Problem Substances : Acetaminophen

Co-administration of N-Acetylcysteine and Acetaminophen efficiently blocks Acetaminophen toxicity.

Article Published Date : Jul 31, 2015
Study Type : Animal Study
Additional Links
Substances : NAC (N-acetyl-L-cysteine) : CK(1429) : AC(366)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355), Liver Damage: Drug-Induced : CK(635) : AC(277)
Pharmacological Actions : Hepatoprotective : CK(8852) : AC(3772)
Problem Substances : Acetaminophen, Paracetamol : CK(859) : AC(296)

Pterostilbene-loaded soluplus/poloxamer 188 mixed micelles for protection against acetaminophen-induced acute liver injury.

Article Published Date : Feb 05, 2023
Study Type : Animal Study
Additional Links
Substances : Pterostilbene : CK(473) : AC(295)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355), Liver Damage: Drug-Induced : CK(635) : AC(277), Oxidative Stress : CK(14395) : AC(5536)
Pharmacological Actions : Antioxidants : CK(34012) : AC(14225), Hepatoprotective : CK(8852) : AC(3772)
Problem Substances : Acetaminophen

Sasa veitchii extracts suppress acetaminophen-induced hepatotoxicity in mice

Article Published Date : Jun 11, 2017
Study Type : Animal Study
Additional Links
Substances : Bamboo : CK(103) : AC(58)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355), Liver Damage: Drug-Induced : CK(635) : AC(277), Oxidative Stress : CK(14395) : AC(5536)
Pharmacological Actions : Antioxidants : CK(34012) : AC(14225), Hepatoprotective : CK(8852) : AC(3772)
Problem Substances : Acetaminophen, Paracetamol : CK(859) : AC(296)

The hepatoprotective effect of prazosin is comparable to N- acetylcysteine against acetaminophen induced hepatotoxicity.

Article Published Date : Feb 29, 2020
Study Type : Animal Study
Additional Links
Substances : NAC (N-acetyl-L-cysteine) : CK(1429) : AC(366)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355), Liver Damage: Drug-Induced : CK(635) : AC(277)
Pharmacological Actions : Hepatoprotective : CK(8852) : AC(3772)
Problem Substances : Acetaminophen, Paracetamol : CK(859) : AC(296)

"Remarkable" 20% Drop in Post-Surgery Opioids With Simple, Safe Supplement

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Thursday, December 5, 2024 - 13:51
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Giving the antioxidant NAC during spine surgery was demonstrated to lower patients' postoperative pain and reduce their need for dangerous opioid drugs

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A combination of resveratrol and quercetin suppressed glomerular damage and apoptosis induced by acetaminophen in the kidney.

Article Published Date : Feb 02, 2020
Study Type : Animal Study
Additional Links
Substances : Quercetin : CK(1864) : AC(847), Resveratrol : CK(3218) : AC(1507)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355), Kidney Damage: Drug-Induced : CK(290) : AC(108)
Pharmacological Actions : Anti-Inflammatory Agents : CK(38674) : AC(15430), Antioxidants : CK(34012) : AC(14225), Renoprotective : CK(4475) : AC(1938), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(11425) : AC(4696)
Problem Substances : Acetaminophen, Paracetamol : CK(859) : AC(296)

A combination strategy of thymoquinone and curcumin might be considered as a potential antidote in combating liver injury induced by acetaminophen.

Article Published Date : Mar 04, 2019
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(7066) : AC(3242), Thymoquinone : CK(1178) : AC(692)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355)
Pharmacological Actions : Hepatoprotective : CK(8852) : AC(3772)
Problem Substances : Acetaminophen, Paracetamol : CK(859) : AC(296)

A crude aqueous leafy extract of M. indica possesses hepatoprotective effects.

Article Published Date : Jun 30, 2022
Study Type : Animal Study
Additional Links
Substances : Mango : CK(569) : AC(300)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355), Liver Damage: Drug-Induced : CK(635) : AC(277)
Pharmacological Actions : Anti-Inflammatory Agents : CK(38674) : AC(15430), Hepatoprotective : CK(8852) : AC(3772)
Problem Substances : Acetaminophen, Paracetamol : CK(859) : AC(296)

A methanolic extract of pomegranate peel ameliorated the hepatic damage caused by acetaminophen.

Article Published Date : Jun 30, 2016
Study Type : Animal Study
Additional Links
Substances : Pomegranate Peel : CK(186) : AC(86)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355)
Pharmacological Actions : Antioxidants : CK(34012) : AC(14225), Hepatoprotective : CK(8852) : AC(3772)
Additional Keywords : Plant Extracts : CK(18619) : AC(6735)
Problem Substances : Acetaminophen, Paracetamol : CK(859) : AC(296)

A perspective on the epidemiology of acetaminophen exposure and toxicity in the United States.

Article Published Date : Apr 30, 2014
Study Type : Review
Additional Links
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355)
Problem Substances : Acetaminophen, Paracetamol : CK(859) : AC(296)

A review of the hepatoprotective effect of kaempferol.

Article Published Date : Dec 31, 2022
Study Type : Review
Additional Links
Substances : Kaempferol : CK(344) : AC(228)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355), Liver Damage : CK(4035) : AC(1836), Liver Disease : CK(351) : AC(112)
Pharmacological Actions : Hepatoprotective : CK(8852) : AC(3772)
Problem Substances : Acetaminophen

A. catechu seed extract is a promising agent for protecting liver from acetaminophen induced hepatotoxicity.

Article Published Date : Nov 30, 2018
Study Type : Animal Study
Additional Links
Substances : Acacia catechu : CK(20) : AC(13)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355), Liver Damage: Drug-Induced : CK(635) : AC(277)
Pharmacological Actions : Antioxidants : CK(34012) : AC(14225), Hepatoprotective : CK(8852) : AC(3772), Superoxide Dismutase Up-regulation : CK(2337) : AC(901)
Additional Keywords : Plant Extracts : CK(18619) : AC(6735)
Problem Substances : Acetaminophen, Paracetamol : CK(859) : AC(296)

A. lappa could protect the liver cells from carbon tetrachloride or acetaminophen-induced liver damages.

Article Published Date : Dec 31, 1999
Study Type : Animal Study
Additional Links
Substances : Burdock : CK(212) : AC(114)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355), Chemically-Induced Liver Damage : CK(2271) : AC(1071)
Pharmacological Actions : Antioxidants : CK(34012) : AC(14225), Hepatoprotective : CK(8852) : AC(3772)
Additional Keywords : Plant Extracts : CK(18619) : AC(6735)
Problem Substances : Acetaminophen, Paracetamol : CK(859) : AC(296)

Acetaminophen affects empathy-like behavior in rats.

Article Published Date : Nov 30, 2018
Study Type : Animal Study
Additional Links
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355)
Additional Keywords : Conventional Medicine Erodes Empathy : CK(83) : AC(9)
Problem Substances : Acetaminophen, Paracetamol : CK(859) : AC(296)

Acetaminophen could cause transient mitochondrial dysfunction that may synergize with other stresses to promote liver damage and steatosis.

Article Published Date : Dec 30, 2015
Study Type : Animal Study
Additional Links
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355), Liver Damage: Drug-Induced : CK(635) : AC(277), Mitochondrial Dysfunction : CK(625) : AC(267)
Problem Substances : Acetaminophen, Paracetamol : CK(859) : AC(296)

Acetaminophen cytotoxicity in HepG2 cells is associated with a decoupling of glycolysis from the TCA cycle.

Article Published Date : Dec 13, 2018
Study Type : In Vitro Study
Additional Links
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355), Chemically-Induced Liver Damage : CK(2271) : AC(1071)
Problem Substances : Acetaminophen, Paracetamol : CK(859) : AC(296)

Acetaminophen elevates unbound bilirubin levels by the glucose oxidase-peroxidase method.

Article Published Date : Aug 31, 2021
Study Type : Human Study
Additional Links
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355), Gastrointestinal Diseases : CK(211) : AC(73)
Problem Substances : Acetaminophen, Paracetamol : CK(859) : AC(296)

Acetaminophen hepatotoxicity is dominated by necrosis or programmed necrosis and does not involve relevant apoptosis.

Article Published Date : Jun 17, 2018
Study Type : Review
Additional Links
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355), Chemically-Induced Liver Damage : CK(2271) : AC(1071)
Problem Substances : Acetaminophen, Paracetamol : CK(859) : AC(296)
Adverse Pharmacological Actions : Necrotic : CK(18) : AC(9)

Acetaminophen is increasingly present in the natural water environment.

Article Published Date : Jul 21, 2019
Study Type : Environmental
Additional Links
Additional Keywords : Environmental Fate of Pharmacueticals : CK(43) : AC(23), Water Pollution
Problem Substances : Acetaminophen, Public Drinking Water : CK(49) : AC(16)

Acetaminophen Linked to Autism and Other Neurological Disorders in Children

Post date:
Thursday, October 6, 2022 - 11:32

Originally published on www.thevaccinereaction.org by Marco Cáceres

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Acetaminophen reduces empathy for other's physical and social pain.

Article Published Date : Apr 30, 2017
Study Type : Review
Additional Links
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355)
Additional Keywords : Conventional Medicine Erodes Empathy : CK(83) : AC(9)
Problem Substances : Acetaminophen, Paracetamol : CK(859) : AC(296)

Acetaminophen reduces glutathione in human tissues which is necessary to detoxify residual formaldehyde present in childhood vaccines.

Article Published Date : Aug 01, 2005
Study Type : Human In Vitro
Additional Links
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355)
Pharmacological Actions : Enzyme Inhibitors : CK(843) : AC(397)
Anti Therapeutic Actions : Vaccination: All : CK(12701) : AC(1349)
Problem Substances : Acetaminophen

Acetaminophen reduces the protein levels of high affinity amino acid permeases and causes tryptophan depletion.

Article Published Date : Sep 30, 2018
Study Type : In Vitro Study
Additional Links
Substances : Tryptophan : CK(281) : AC(34)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355)
Problem Substances : Acetaminophen, Paracetamol : CK(859) : AC(296)

Acetaminophen toxicity induces mitochondrial complex I inhibition in human liver tissue.

Article Published Date : Aug 11, 2019
Study Type : Animal Study, Human In Vitro
Additional Links
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355), Chemically-Induced Liver Damage : CK(2271) : AC(1071)
Problem Substances : Acetaminophen

Acetaminophen use for fever in children associated with autism spectrum disorder.

Article Published Date : Mar 31, 2016
Study Type : Human Study
Additional Links
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355), Autism Spectrum Disorders : CK(3679) : AC(559)
Additional Keywords : Endocannabinoid System : CK(157) : AC(56)
Problem Substances : Acetaminophen, Paracetamol : CK(859) : AC(296)

Acetaminophen-induced liver injury: Molecular mechanism and treatments from natural products.

Article Published Date : Dec 31, 2022
Study Type : Animal Study
Additional Links
Substances : Polyphenols : CK(2729) : AC(997), Sulforaphane : CK(1342) : AC(629)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355), Liver Damage: Drug-Induced : CK(635) : AC(277)
Pharmacological Actions : Antioxidants : CK(34012) : AC(14225), Hepatoprotective : CK(8852) : AC(3772)
Problem Substances : Acetaminophen

Adverse effects of aspirin, acetaminophen, and ibuprofen on immune function, viral shedding, and clinical status in rhinovirus-infected volunteers.

Article Published Date : Nov 30, 1990
Study Type : Human Study
Additional Links
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355), Common Cold : CK(859) : AC(124), Rhinovirus Infection : CK(97) : AC(39)
Additional Keywords : Increased Risk : CK(8703) : AC(1109), Viral Shedding
Problem Substances : Acetaminophen, Aspirin : CK(661) : AC(112), Ibuprofen : CK(266) : AC(41), Paracetamol : CK(859) : AC(296)
Adverse Pharmacological Actions : Immunosuppressive : CK(289) : AC(55)

Aged citrus peel (Chenpi) prevents acetaminophen-induced Hepatotoxicity by epigenetically regulating Nrf2 pathway.

Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Citrus Peel : CK(159) : AC(62)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355), Liver Damage : CK(4035) : AC(1836)
Pharmacological Actions : Antioxidants : CK(34012) : AC(14225), Heme oxygenase-1 up-regulation : CK(1313) : AC(763), Hepatoprotective : CK(8852) : AC(3772), Nrf2 activation : CK(3111) : AC(1770)
Problem Substances : Acetaminophen, Paracetamol : CK(859) : AC(296)

Allicin and omega-3 fatty acids attenuates acetaminophen mediated renal toxicity.

Article Published Date : Jul 11, 2023
Study Type : Animal Study
Additional Links
Substances : Allicin : CK(360) : AC(196), Omega-3 Fatty Acids : CK(5655) : AC(768)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355), Kidney Damage: Drug-Induced : CK(290) : AC(108)
Pharmacological Actions : Antioxidants : CK(34012) : AC(14225), Renoprotective : CK(4475) : AC(1938)
Problem Substances : Acetaminophen

Ameliorative effects of berberine and selenium against paracetamol-induced hepatic toxicity in rats.

Article Published Date : Dec 31, 2023
Study Type : Animal Study
Additional Links
Substances : Berberine : CK(2481) : AC(1078), Selenium : CK(1750) : AC(391)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355), Oxidative Stress : CK(14395) : AC(5536)
Pharmacological Actions : Antioxidants : CK(34012) : AC(14225), Hepatoprotective : CK(8852) : AC(3772)
Problem Substances : Acetaminophen

Ameliorative effects of corn silk extract on acetaminophen-induced renal toxicity.

Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Corn Silk : CK(121) : AC(51)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355), Kidney Damage: Drug-Induced : CK(290) : AC(108), Oxidative Stress : CK(14395) : AC(5536)
Pharmacological Actions : Renoprotective : CK(4475) : AC(1938)
Additional Keywords : Plant Extracts : CK(18619) : AC(6735)
Problem Substances : Acetaminophen, Paracetamol : CK(859) : AC(296)

An aqueous extract of white clover was protective against the hepatotoxicity induced by acetaminophen.

Article Published Date : Aug 31, 2019
Study Type : Animal Study
Additional Links
Substances : White Clover : CK(11) : AC(7)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355)
Pharmacological Actions : Antioxidants : CK(34012) : AC(14225), Hepatoprotective : CK(8852) : AC(3772)
Problem Substances : Acetaminophen, Paracetamol : CK(859) : AC(296)

An extract from Mulberry leaf decelerates acetaminophen induced hepatic inflammation.

Article Published Date : Sep 30, 2017
Study Type : Animal Study
Additional Links
Substances : Mulberry : CK(546) : AC(274)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355)
Pharmacological Actions : Anti-Inflammatory Agents : CK(38674) : AC(15430)
Problem Substances : Acetaminophen, Paracetamol : CK(859) : AC(296)

An isoflavonoid from seeds of Lepidium sativum L. has a protective effect on hepatotoxicity induced by paracetamol.

Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Garden Cress (Lepidium sativum) : CK(65) : AC(32)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355), Chemically-Induced Liver Damage : CK(2271) : AC(1071), Oxidative Stress : CK(14395) : AC(5536)
Pharmacological Actions : Antioxidants : CK(34012) : AC(14225), Hepatoprotective : CK(8852) : AC(3772)
Additional Keywords : Plant Extracts : CK(18619) : AC(6735)
Problem Substances : Acetaminophen, Paracetamol : CK(859) : AC(296)

An unexpected role of cholesterol sulfotransferase and its regulation in sensitizing mice to acetaminophen induced liver injury.

Article Published Date : Apr 02, 2019
Study Type : Animal Study
Additional Links
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355), Chemically-Induced Liver Damage : CK(2271) : AC(1071)
Problem Substances : Acetaminophen, Paracetamol : CK(859) : AC(296)

Angelica sinensis polysaccharide protects against acetaminophen-induced acute liver injury

Article Published Date : Apr 30, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355), Chemically-Induced Liver Damage : CK(2271) : AC(1071), Lipid Peroxidation : CK(1995) : AC(780), Oxidative Stress : CK(14395) : AC(5536)
Pharmacological Actions : Anti-Apoptotic : CK(5418) : AC(3083), Antioxidants : CK(34012) : AC(14225), Hepatoprotective : CK(8852) : AC(3772), Malondialdehyde Down-regulation : CK(2976) : AC(969)
Problem Substances : Acetaminophen, Paracetamol : CK(859) : AC(296)

Anthropogenic contaminants of high concern: Existence in water resources and their adverse effects.

Article Published Date : Nov 09, 2019
Study Type : Environmental
Additional Links
Additional Keywords : Environmental Fate of Pharmacueticals : CK(43) : AC(23), Public Drinking Water : CK(37) : AC(7), Water Pollution
Problem Substances : Acetaminophen, Diclofenac : CK(231) : AC(52), Ibuprofen : CK(266) : AC(41), Naproxen : CK(68) : AC(10), Ofloxacin : CK(4) : AC(2), Pesticides : CK(2365) : AC(482), Ranitidine : CK(14) : AC(3), Triclosan : CK(168) : AC(47)

Antihepatotoxic benefits of Poria cocos polysaccharides on acetaminophen-lesioned livers in vivo and in vitro.

Article Published Date : Apr 30, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Poria cocos : CK(200) : AC(108)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355), Liver Damage: Drug-Induced : CK(635) : AC(277)
Pharmacological Actions : Hepatoprotective : CK(8852) : AC(3772)
Problem Substances : Acetaminophen, Paracetamol : CK(859) : AC(296)

Apigenin alleviated acetaminophen-induced hepatotoxicity in low protein-fed rats.

Article Published Date : Feb 10, 2020
Study Type : Animal Study
Additional Links
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355), Liver Damage: Drug-Induced : CK(635) : AC(277)
Pharmacological Actions : Anti-Inflammatory Agents : CK(38674) : AC(15430), Hepatoprotective : CK(8852) : AC(3772), Interleukin-1 beta downregulation : CK(5920) : AC(2873)
Problem Substances : Acetaminophen, Paracetamol : CK(859) : AC(296)

Apigenin attenuates acetaminophen-induced hepatotoxicity.

Article Published Date : Dec 31, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Apigenin : CK(676) : AC(391)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355), Liver Damage: Drug-Induced : CK(635) : AC(277)
Pharmacological Actions : Antioxidants : CK(34012) : AC(14225), Hepatoprotective : CK(8852) : AC(3772), Nrf2 activation : CK(3111) : AC(1770)
Problem Substances : Acetaminophen, Paracetamol : CK(859) : AC(296)

Apigenin prevents acetaminophen-induced liver injury by activating the SIRT1 pathway.

Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Apigenin : CK(676) : AC(391)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355), Liver Damage: Drug-Induced : CK(635) : AC(277)
Pharmacological Actions : Antioxidants : CK(34012) : AC(14225), Autophagy Up-regulation : CK(830) : AC(554), Hepatoprotective : CK(8852) : AC(3772), SIRT1 Activator : CK(380) : AC(188)
Problem Substances : Acetaminophen, Paracetamol : CK(859) : AC(296)

Apigenin significantly increases the enzyme antioxidant defence mechanisms in paracetamol-induced hepatotoxicity.

Article Published Date : Mar 01, 2017
Study Type : Animal Study
Additional Links
Substances : Apigenin : CK(676) : AC(391)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355), Liver Damage: Drug-Induced : CK(635) : AC(277)
Pharmacological Actions : Antioxidants : CK(34012) : AC(14225), Hepatoprotective : CK(8852) : AC(3772)
Problem Substances : Acetaminophen, Paracetamol : CK(859) : AC(296)

Aqueous extracts of C. papaya may be useful in preventing carbon tetrachloride and acetaminophen induced liver toxicities.

Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Papaya : CK(309) : AC(124)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355), Chemically-Induced Liver Damage : CK(2271) : AC(1071)
Pharmacological Actions : Antioxidants : CK(34012) : AC(14225), Hepatoprotective : CK(8852) : AC(3772)
Additional Keywords : Plant Extracts : CK(18619) : AC(6735)
Problem Substances : Acetaminophen, Paracetamol : CK(859) : AC(296)

Aqueous extracts of Rosa damascene may prevent hepatic damage from acetaminophen induced toxicity in rats.

Article Published Date : Dec 31, 2011
Study Type : Animal Study
Additional Links
Substances : Rose : CK(834) : AC(279)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355), Chemically-Induced Liver Damage : CK(2271) : AC(1071), Lipid Peroxidation : CK(1995) : AC(780), Oxidative Stress : CK(14395) : AC(5536)
Pharmacological Actions : Antioxidants : CK(34012) : AC(14225)
Additional Keywords : Phytotherapy : CK(3963) : AC(1016), Plant Extracts : CK(18619) : AC(6735)
Problem Substances : Acetaminophen, Paracetamol : CK(859) : AC(296)

Arctium lappa can prevent most of the hepatic tissue damage caused by acetaminophen overdose in rats.

Article Published Date : Nov 30, 2015
Study Type : Animal Study
Additional Links
Substances : Burdock : CK(212) : AC(114)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355)
Pharmacological Actions : Hepatoprotective : CK(8852) : AC(3772)
Problem Substances : Acetaminophen, Paracetamol : CK(859) : AC(296)

Are Herbs Really Damaging People's Livers? A Closer Look at the Facts Behind the Claim

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Thursday, September 5, 2024 - 12:10
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In recent years, a narrative has emerged warning the public that herbal supplements may be damaging their livers. Mainstream media headlines such as "6 Supplements, Including Green Tea, Turmeric, Linked to Liver Toxicity" and "Silent Threats: Everyday Herbs and Drugs Linked to Liver Damage" have contributed to a growing sense of fear around herbal products. But how valid are these claims?

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Ascorbic acid prevents acetaminophen-induced hepatotoxicity in mice.

Article Published Date : Jun 06, 2016
Study Type : Animal Study
Additional Links
Substances : Vitamin C : CK(6051) : AC(1403)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355)
Pharmacological Actions : Hepatoprotective : CK(8852) : AC(3772)
Problem Substances : Acetaminophen, Paracetamol : CK(859) : AC(296)

Association of acetaminophen use during pregnancy with behavioural problems in childhood.

Article Published Date : Sep 30, 2016
Study Type : Human Study
Additional Links
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355), Attention Deficit Disorder with Hyperactivity : CK(633) : AC(84), Prenatal Chemical Exposures : CK(2428) : AC(530)
Problem Substances : Acetaminophen, Paracetamol : CK(859) : AC(296)

Astaxanthin ameliorated acetaminophen-induced liver injury.

Article Published Date : Sep 11, 2022
Study Type : Animal Study
Additional Links
Substances : Astaxanthin : CK(1627) : AC(648)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(889) : AC(355)
Pharmacological Actions : Antioxidants : CK(34012) : AC(14225), Heme oxygenase-1 up-regulation : CK(1313) : AC(763), Hepatoprotective : CK(8852) : AC(3772), Nrf2 activation : CK(3111) : AC(1770)
Problem Substances : Acetaminophen

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