Methylcholanthrene

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1 Diseases Researched for Methylcholanthrene

Name	AC	CK	Focus
Cancers: All	1	1

Research Articles 1
Cumulative Knowledge Score 1
Overall Research Rating GOOD

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1 Abstracts with Methylcholanthrene Research

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SV40 works synergistically with methylcholanthrene to elicit tumors.Jan 01, 2010

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Pubmed Data : Cancer Cell Int. 2010;10:4. Epub 2010 Feb 23. PMID: 20178601

Article Published Date : Jan 01, 2010

Study Type : Commentary

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Diseases : Cancers: All

Additional Keywords : Cellular Immortalization

Problem Substances : Methylcholanthrene, Simian virus 40 (SV40)

Research Articles 1
Cumulative Knowledge Score 1
Overall Research Rating GOOD

Methylcholanthrene (MCA) is a highly carcinogenic polycyclic aromatic hydrocarbon produced by burning organic compounds at very high temperatures^{[clarification needed]}. It is a yellow solid with a melting pont around 180 °C. Methylcholanthrene is used in laboratory studies of chemical carcinogenesis. It is an alkylated derivative of benz[a]anthracene and has a similar UV spectrum. The most common isomer is 3-methylcholanthrene, although the methyl group can occur in other places.

3-Methylcholanthrene, a known carcinogen which builds up in the prostate due to cholesterol breakdown, is implicated in prostate cancer.^{[citation needed]} It "readily produces" primary sarcomas in mice.^[1]

[Source: Wikipedia]

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