Cardiotoxic

Name	AC	CK
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)	7	73
Statin Drugs	13	71
Energy Drinks	11	69
Rosiglitazone (trade name Avandia)	5	62
Trans Fatty Acids	7	62
Hydrogenated Oil	6	61
Bisphenol A	16	55
Ibuprofen	5	53
Aspirin	4	50
Calcium Carbonate	2	40
Glipizide	2	40
Rofecoxib	3	40
Proton-Pump Inhibitors	6	37
Fructose	6	36
Simvastatin	7	32
Celecoxib	2	30
Diclofenac	2	30
Lovastatin	6	25
Sodium Fluoride	9	23
Casein	2	21
Casein: A1	2	21
Fluoride	7	21
Corticosteroid	1	20
Glibenclamide	1	20
Glyburide	1	20
Oral Contraceptives	1	20
Prednisone	1	20
Raloxifene	2	20
Sugar Sweetened Beverages	2	20
Sulfonylureas	1	20
Aluminum	3	14
High Fructose Corn Syrup	3	14
Atorvastatin	3	13
Phthalates	3	13
Antipsychotic Drugs	3	12
Adderall	2	11
Amphetamine	2	11
Dextroamphetamine	2	11
Angiotensin-Converting Enzyme (ACE) Inhibitor	1	10
Antidepressants	1	10
Beta Blockers	1	10
Calcium Channel Antagonists	1	10
Fluoxetine (trade name Prozac)	1	10
Gluten	1	10
Iloperidone	1	10
Indomethacin	1	10
Naproxen	1	10
Selective Serotonin Reuptake Inhibitors (SSRIs)	1	10
Sucrose	1	10
Sugary soda	1	10
Tobacco: Smoking	1	10
Valdecoxib	1	10
Bisphenol S	4	6
Electronic Cigarettes	4	6
Esomeprazole (trade name Nexium)	1	5
Glyphosate	2	4
Paraquat	2	4
Testoterone: Exogenous	2	4
Lamivudine	1	3
Mesalamine	1	3
vaccines	1	3
Arsenic	1	2
Arsenic Trioxide	1	2
Cell Phone Exposure	1	2
Deltamethrin	1	2
Doxorubicin	1	2
Fluvastatin	1	2
Monosodium Glutamate (MSG)	1	2
Pesticides	1	2
Triclosan	1	2
Vaccine Adjuvants	1	2
Acrylamide	1	1
Homocysteine	1	1
Mercury	1	1
Polysorbate 80	1	1
Sirolimus	1	1
Thimerosal	1	1
Uranium: Depleted	1	1

Name	AC	CK
Coronary Artery Disease	19	251
Cardiovascular Diseases	25	241
Myocardial Infarction	19	234
Cardiac Mortality	12	122
Diabetes Mellitus: Type 2	6	110
Diabetes: Cardiovascular Illness	6	100
Heart Failure	13	97
Hypertension	8	64
Stroke	3	50
Statin-Induced Pathologies	10	42
Mortality: All-Cause	3	40
Atrial Fibrillation	4	34
Congestive Heart Failure	4	34
Bisphenol Toxicity	13	33
Drug-Induced Nutrient Depletion: Statin Drugs	7	30
Heart Attack	2	30
Heart Disease: Ischemic	2	30
Atherosclerosis	5	25
Endothelial Dysfunction	4	24
Inflammation	4	24
Arrhythmias: Cardiac	3	23
Cardiomyopathy	3	22
Insulin Resistance	2	22
Diabetes Mellitus: Type 1: Prevention	2	21
Cardiac Arrest	2	20
Cerebral Ischemia	1	20
Cerebral Stroke	1	20
High Cholesterol	2	20
NSAID-induced toxicity	2	20
Coenzyme Q10 Deficiency	3	14
Oxidative Stress	4	14
Arterial Calcification	3	13
Cardiac Arrhythmias	2	13
Radiation Induced Illness	3	13
Fluoride Toxicity	6	12
Coronary Stenting	2	11
Dyslipidemias	2	11
Lipid Peroxidation	2	11
Air Pollution Linked Toxicity	1	10
All-Cause Mortality	1	10
Angina Pectoris	1	10
Aortic Calcification	1	10
Apolipoprotein A/B ratio imbalances	1	10
Carotid Artery Narrowing	1	10
Celiac Disease	1	10
Cholesterol: LDL/HDL ratio	1	10
Cholesterol: Oxidation	1	10
Congenital Defects	1	10
Coronary Artery Ecstasia	1	10
Deep Vein Thrombosis	1	10
Elderly: Age Specific Diseases	1	10
Heart Rate Variability: Increased	1	10
Hemodialysis	1	10
Intima Media Thickening	1	10
Myocardial Infarction: Prevention	1	10
Myocarditis: Autoimmune	1	10
Prenatal Chemical Exposures	1	10
Pulmonary Embolism	1	10
Radiation Induced Illness: Heart	1	10
Smoking	1	10
Thrombosis	1	10
Triglycerides: Elevated	1	10
Venous Thrombosis	1	10
Cardiac Hypertrophy	2	4
DNA damage	2	4
Fetal Origin of Adult Disease	2	4
Glyphosate Toxicity	2	4
Myocardial Ischemia	2	4
Pesticide Toxicity	2	4
Aging	3	3
Drug-Induced Toxicity	1	3
Hepatitis B	1	3
Mitochondrial Diseases	1	3
Mitochondrial Dysfunction	2	3
Myocarditis	1	3
Pericarditis	1	3
Phthalate Toxicity	2	3
Rhabdomyolysis	1	3
Vaccine-induced Toxicity	1	3
Aluminum Toxicity	1	2
Anxiety	1	2
Atheroma	1	2
Birth Defects	1	2
Bisphenol S Toxicity	1	2
Brain Cancer	1	2
Cardiomegaly	1	2
Chemotherapy-Induced Toxicity	1	2
Chronic Kidney Disease (CKD)	1	2
Ectopic Calcification	1	2
Fructose-Induced Toxicity	1	2
Headache	1	2
Herbicide Toxicity	1	2
Schwannoma	1	2
Arteriosclerosis	1	1
Cancers: Pediatric	1	1
Cardiotoxicity: Chemotherapy-Induced	1	1
Cardiovascular Disease	1	1
Chemotherapy-Induced Toxicity: Doxorubicin	1	1
Fluorosis	1	1
Infertility: Male	1	1
Metabolic Diseases	1	1

Additional Keywords : Drug: Metformin

Problem Substances : Sulfonylureas

Adverse Pharmacological Actions : Cardiotoxic

[+]

The consumption of cow milk A1 beta-casein is associated with increased risk of ischaemic heart disease and type 1 diabets. Jan 24, 2003

Click here to read the entire abstract

Pubmed Data : N Z Med J. 2003 Jan 24;116(1168):U295. Epub 2003 Jan 24. PMID: 12601419

[+]

Atorvastatin worsens left ventricular diastolic function, which is improved through coenzyme q10 supplementation. Nov 15, 2004

Click here to read the entire abstract

Pubmed Data : Am J Cardiol. 2004 Nov 15 ;94(10):1306-10. PMID: 15541254

Article Published Date : Nov 15, 2004

Energy drinks induce acute cardiovascular and metabolic changes pointing to potential risks for young adults.Feb 25, 2019

Click here to read the entire abstract

Pubmed Data : J Nutr. 2019 Feb 26. Epub 2019 Feb 26. PMID: 30805607

Pubmed Data : Climacteric. 2009;12 Suppl 1:108-11. PMID: 19811253

Statin-induced reduction in HDL-C was relatively common and was associated with increased risk of major adverse cardiovascular events.Dec 29, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Clin Drug Investig. 2015 Dec 30. Epub 2015 Dec 30. PMID: 26718960

Article Published Date : Dec 29, 2015

Study Type : Human Study

Additional Links

Additional Keywords : Increased Risk

Problem Substances : Simvastatin, Statin Drugs

Adverse Pharmacological Actions : Cardiotoxic

[+]

Sucrose consumption higher than 15% is associated with an increased risk of a coronary events.Oct 23, 2016

Click here to read the entire abstract

Pubmed Data : Br J Nutr. 2016 Oct 24:1-10. Epub 2016 Aug 24. PMID: 27774913

[+]

These results indicate that exposure to radiofrequency EMF may affect the neurovegetative regulation.Sep 01, 2012

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Occup Med Environ Health. 2012 Sep ;25(4):446-55. Epub 2012 Dec 6. PMID: 23224733

Article Published Date : Sep 01, 2012

Study Type : Human Study

Additional Links

Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation

Adverse Pharmacological Actions : Cardiotoxic, Neurotoxic

[+]

These results showed that even a single can of energy drinks can acutely increase atrial electromechanical conduction times in young adults.Nov 18, 2019

Click here to read the entire abstract

Pubmed Data : Am J Cardiol. 2019 Nov 19. Epub 2019 Nov 19. PMID: 31812229

Article Published Date : Nov 18, 2019

Study Type : Human Study

Additional Links

Diseases : Atrial Fibrillation

Additional Keywords : Increased Risk

Problem Substances : Energy Drinks

Adverse Pharmacological Actions : Cardiotoxic

[+]

This study supports the association of proton pump inhibitors exposure with risk for myocardial infarction in the general population.Dec 31, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : Eur Heart J Cardiovasc Pharmacother. 2016 Dec 26. Epub 2016 Dec 26. PMID: 28025218

Article Published Date : Dec 25, 2016

Study Type : Human Study

Additional Links

Diseases : Cardiac Arrest, NSAID-induced toxicity

Additional Keywords : Increased Risk

Problem Substances : Celecoxib, Diclofenac, Ibuprofen, Naproxen, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), Rofecoxib

Adverse Pharmacological Actions : Cardiotoxic

[+]

Use of proton pump inhibitors is associated with an increase in adverse cardiovascular events in patients with hemodialysis.Nov 13, 2019

Click here to read the entire abstract

Pubmed Data : Eur J Intern Med. 2019 Nov 14. Epub 2019 Nov 14. PMID: 31735546

Click here to read the entire abstract

Pubmed Data : J Emerg Med. 1999 Sep-Oct;17(5):851-7. PMID: 10499702

Article Published Date : Sep 01, 1999

Study Type : Human: Case Report

Additional Links

Diseases : Atrial Fibrillation

Problem Substances : Testoterone: Exogenous

Adverse Pharmacological Actions : Cardiotoxic

[+]

A case of simvastatin-induced acute rhabdomyolysis with heart failure after initiation of treatment with fusidic acid has been reported.Apr 01, 1992

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Pubmed Data : Rev Rhum Mal Osteoartic. 1992 Apr ;59(4):281-3. PMID: 1496277

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Pubmed Data : Anaesthesia. 2005 Aug;60(8):806-10. PMID: 16029231

Pubmed Data : BMJ Case Rep. 2018 Mar 22 ;2018. Epub 2018 Mar 22. PMID: 29572367

Article Published Date : Mar 22, 2018

Study Type : Human: Case Report

Additional Links

Diseases : Myocarditis, Vaccine-induced Toxicity

Additional Keywords : Vaccine Research

Anti Therapeutic Actions : Vaccination: Smallpox

Problem Substances : vaccines

Adverse Pharmacological Actions : Cardiotoxic

[+]

Acute exposure to triclosan has the potential to cause subtle cardiac toxicity in developing fish.Apr 19, 2016

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Pubmed Data : Zebrafish. 2016 Apr 20. Epub 2016 Apr 20. PMID: 27097057

Article Published Date : Apr 19, 2016

Study Type : Animal Study

Additional Links

Problem Substances : Triclosan

Adverse Pharmacological Actions : Cardiotoxic

[+]

Alpha-lipoic acid reduced uric acid levels, oxidative stress, and corrected vascular responses that were induced by consumption of high-fructose corn syrup.Mar 28, 2015

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Pubmed Data : Hum Exp Toxicol. 2015 Mar 29. Epub 2015 Mar 29. PMID: 25825413

Article Published Date : Mar 28, 2015

Study Type : Animal Study

Click here to read the entire abstract

Pubmed Data : Am J Physiol Heart Circ Physiol. 2011 Dec 23. Epub 2011 Dec 23. PMID: 22198170

Article Published Date : Dec 23, 2011

Study Type : Animal Study

Additional Links

Diseases : Cardiovascular Diseases

Problem Substances : Fructose

Adverse Pharmacological Actions : Cardiotoxic

[+]

Effect of water fluoridation on the development of medial vascular calcification in uremic rats.Apr 05, 2014

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Pubmed Data : Toxicology. 2014 Apr 6 ;318:40-50. Epub 2014 Feb 18. PMID: 24561004

In BPA treated females cardiomyopathy incidence and severity was significantly increased compared to control females.May 08, 2017

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Pubmed Data : Toxicol Lett. 2017 May 9. Epub 2017 May 9. PMID: 28499613

Article Published Date : May 08, 2017

Study Type : Animal Study

Additional Links

Diseases : Bisphenol Toxicity, Cardiomyopathy

Additional Keywords : Increased Risk

Problem Substances : Bisphenol A

Adverse Pharmacological Actions : Cardiotoxic

[+]

Intermittent mobile phone exposure results in a significant increase in embryonic mortality and cardiac deformity in chicken embryos.Jun 01, 2016

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Pubmed Data : Anat Histol Embryol. 2016 Jun ;45(3):197-208. Epub 2015 Jul 14. PMID: 26171674

Click here to read the entire abstract

Pubmed Data : Am J Physiol Heart Circ Physiol. 2021 Jan 29. Epub 2021 Jan 29. PMID: 33513085

Article Published Date : Jan 28, 2021

Study Type : Animal Study

Additional Links

Diseases : Pesticide Toxicity

Problem Substances : Paraquat

Adverse Pharmacological Actions : Cardiotoxic

[+]

Paternal inheritance of bisphenol A cardiotoxic effects: The implications of sperm epigenome.Feb 19, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Sci. 2021 Feb 20 ;22(4). Epub 2021 Feb 20. PMID: 33672782

Article Published Date : Feb 19, 2021

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Bisphenol Toxicity, Fetal Origin of Adult Disease

Pharmacological Actions : Cytoprotective

Additional Keywords : Transgenerational inheritance

Problem Substances : Bisphenol A

Adverse Pharmacological Actions : Cardiotoxic

[+]

Phthalates may disrupt heart rate variability and cardiovascular reactivity.Aug 24, 2017

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Pubmed Data : Am J Physiol Heart Circ Physiol. 2017 Aug 25:ajpheart.00364.2017. Epub 2017 Aug 25. PMID: 28842438

Click here to read the entire abstract

Pubmed Data : Food Funct. 2012 Feb 8. Epub 2012 Feb 8. PMID: 22314573

Article Published Date : Feb 08, 2012

Study Type : Animal Study

Additional Links

Substances : Quercetin

Diseases : Fluoride Toxicity

Pharmacological Actions : Antioxidants, Cardioprotective

Problem Substances : Sodium Fluoride

Adverse Pharmacological Actions : Cardiotoxic, Oxidant

[+]

Rapid exposure to low-dose BPS showed proarrhythmic impact on female rat hearts; these effects at the organ, cellular, and molecular levels are remarkably similar to those reported for BPA.May 31, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

A review of energy drinks and the risk of cardiovascular disease.Jun 06, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cureus. 2017 Jun 7 ;9(6):e1322. Epub 2017 Jun 7. PMID: 28690955

Article Published Date : Jun 06, 2017

Study Type : Review

Additional Links

Additional Keywords : Risk Factors

Problem Substances : Energy Drinks

Adverse Pharmacological Actions : Cardiotoxic

[+]

A review of proton pump inhibitors and the risk of severe adverse events.May 23, 2018

Click here to read the entire abstract

Pubmed Data : Rev Port Cardiol. 2018 May 24. Epub 2018 May 24. PMID: 29804887

Click here to read the entire abstract

Pubmed Data : Environ Res. 2018 Sep 19 ;168:1-6. Epub 2018 Sep 19. PMID: 30243215

Article Published Date : Sep 18, 2018

Study Type : Commentary

Additional Links

Anti Therapeutic Actions : Mobile Phone Radiation

Adverse Pharmacological Actions : Cardiotoxic, Neurotoxic

[+]

Anabolic steroid abuse may be a risk factor for atrial fibrillation. Nov 19, 2010

Click here to read the entire abstract

Pubmed Data : Int J Cardiol. 2010 Nov 19;145(2):365-7. Epub 2010 Mar 9. PMID: 20215037

Article Published Date : Nov 19, 2010

Study Type : Review

Additional Links

Diseases : Atrial Fibrillation

Problem Substances : Testoterone: Exogenous

Adverse Pharmacological Actions : Cardiotoxic

[+]

Antipsychotic adverse effects are diverse and frequently experienced, but are not often systematically assessed.Mar 31, 2015

Click here to read the entire abstract

Pubmed Data : J Psychopharmacol. 2015 Apr ;29(4):353-62. Epub 2014 Dec 16. PMID: 25516373

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2012 ;7(7):e41667. Epub 2012 Jul 27. PMID: 22848561

Click here to read the entire abstract

Pubmed Data : Toxicol Appl Pharmacol. 2021 Aug 19:115696. Epub 2021 Aug 19. PMID: 34419494

Article Published Date : Aug 18, 2021

Study Type : In Vitro Study

Additional Links

Diseases : Bisphenol Toxicity, Cardiovascular Diseases

Additional Keywords : Risk Factors

Problem Substances : Bisphenol A

Adverse Pharmacological Actions : Cardiotoxic

[+]

Cardiovascular risk of proton pump inhibitors.Jun 30, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Methodist Debakey Cardiovasc J. 2019 Jul-Sep;15(3):214-219. PMID: 31687101

Click here to read the entire abstract

Pubmed Data : Pharmacology. 2008 ;82(1):74-82. Epub 2008 May 27. PMID: 18504415

Article Published Date : Jan 01, 2008

Study Type : In Vitro Study

Additional Links

Diseases : Heart Failure, Statin-Induced Pathologies

Problem Substances : Lovastatin, Statin Drugs

Adverse Pharmacological Actions : Cardiotoxic, Cytotoxic

[+]

The use of e-cigarettes in humans is associated with significant adverse cardiorespiratory and immunological changes.Mar 04, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Curr Addict Rep. 2021 Mar 5:1-11. Epub 2021 Mar 5. PMID: 33717828

Article Published Date : Mar 04, 2021

Study Type : Review

Additional Links

Diseases : Inflammation

Additional Keywords : Risk Factors

Problem Substances : Electronic Cigarettes

Adverse Pharmacological Actions : Cardiotoxic, Immunoreactive

[+]

Trans-unsaturated fatty acids and acrylamide in food appear to contribute to atherosclerosis progression.Jan 01, 2003

Click here to read the entire abstract

Pubmed Data : Acta Microbiol Pol. 2003 ;52 Suppl:75-81. PMID: 15058816

Article Published Date : Jan 01, 2003

Study Type : Review

Additional Links

Diseases : Atherosclerosis, Cardiovascular Diseases

Problem Substances : Acrylamide , Trans Fatty Acids

Adverse Pharmacological Actions : Cardiotoxic

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View the Evidence: 166 Abstracts with Cardiotoxic Research

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There is a trend toward an increased overall mortality risk with glyburide versus glimepiride and glipizide versus glimepiride (1.39 [0.99-1.96]) in those with documented coronary artery disease.Jun 01, 2010

Among patients with impaired glucose tolerance or type 2 diabetes, rosiglitazone use for at least 12 months is associated with a significantly increased risk of myocardial infarction and heart failure.Sep 12, 2007

Calcium supplements with or without vitamin D increase the risk of cardiovascular events.Jan 01, 2011

Cardiovascular Effects of Calcium SupplementsJun 30, 2013

Consumption of trans-fatty acids from partially hydrogenated oils adversely affects multiple cardiovascular risk factors and contributes significantly to increased risk of oronary heart disease events.May 01, 2009

Corticosteroids increase the risk of atrial fibrillation.May 08, 2006

Initiating treatment of type 2 diabetes with glibenclamide or glipizide is associated with increased risk of coronary artery disease in comparison to gliclazide or glimepiride.Dec 01, 2008

Low-dose oral contraceptive use significantly increases the risk of both cardiac and vascular arterial events events.Jul 01, 2005

Nonsteroidal antinflammatory drugs increase cardiovascular events in patients after hospitalization for serious coronary heart disease.May 01, 2009

Patients taking aspirin before an acute coronary syndrome (ACS) are at higher risk of recurrent heart attack.Oct 19, 2010

Rosiglitazone was associated with a significant increase in the risk of myocardial infarction and with an increase in the risk of death from cardiovascular causes.Jun 14, 2007

Sulfonylureas are associated with an increased risk of adverse cardiovascular events in type 2 diabetic patients.Jun 01, 2009

The consumption of cow milk A1 beta-casein is associated with increased risk of ischaemic heart disease and type 1 diabets. Jan 24, 2003

The impact of acute energy drink consumption on electrical heart disease.Feb 08, 2021

"Circulating levels of bisphenol A and phthalates are related to carotid atherosclerosis in the elderly."Sep 01, 2011

"Circulating levels of metals are related to carotid atherosclerosis in elderly."Dec 15, 2011

Adderrall use has been linked to cardiomyopathy and heart failure.May 01, 2008

Association between short-term exposure to ambient fine particulate matter and myocardial injury.Feb 04, 2021

Astaxanthin protects smokers against oxidative stress. Sep 01, 2011

Atorvastatin worsens left ventricular diastolic function, which is improved through coenzyme q10 supplementation. Nov 15, 2004

Beta Blockers, Calcium Channel Blockers, Angiotensin-Converting Enzyme (ACE) Inhibitor in combination with Diuretics are associated wtih increased risk for cardiovascular mortality versus Diuretics alone. Dec 15, 2004

Celiac disease has been associated with autoimmune myocarditis.Jun 04, 2002

Chronic fluoride exposure has an important role in pathogenesis of coronary artery ectasia.Nov 01, 2011

Dietary intake of trans fatty acids is associated with increase in the risk of coronary artery disease.Jan 01, 2008

Energy drinks increased systolic blood pressure, altered electrolytes, and resulted in repolarization abnormalities.Jun 30, 2016

Energy drinks induce acute cardiovascular and metabolic changes pointing to potential risks for young adults.Feb 25, 2019

Harmful effects of NSAIDs among patients with hypertension and coronary artery disease include increased cardiac mortality. Jul 01, 2011

High fructose corn syrup and fructose consumption increase risk factors for cardiovascular disease in human subjects.Aug 17, 2011

Ibuprofen use may increase the risk of thrombotic and congestive heart failure events.Jun 01, 2007

In patients undergoing percutaneous coronary intervention with drug-eluting stents the use of proton pump inhibitors was associated with a greater rate of major adverse cardiac events.Mar 15, 2010

In this study, EMF has a seemingly weak interaction with heart rate variability parameters.Feb 01, 2007

Increases in urinary BPA concentrations are associated with increased incidence of coronary artery disease. Feb 21, 2012

Intake of trans-fatty acids contributes to a sizeable proportion of coronary heart disease events in Iran.Aug 01, 2007

Lovastatin decreases coenzyme Q levels associated with compromised cardiac function in humans.Nov 01, 1990

Lovastatin enhances the susceptibility of LDL cholesterol to oxidation.Jun 30, 1997

Mobile phone radiation alters heart rate variability in healthy subjects.Dec 01, 2010

Mobile phone radiation may alter heart rate variability during call time.Aug 01, 2008

More frequent statin use is associated with accelerated coronary artery calcification, and in a subpopulation aortic calcification, in T2DM patients with advanced atherosclerosis.Aug 07, 2012

Patients are at increased risk of cardiac proarrhythmia during iloperidone treatment, as this drug possesses significant cardiac repolarization-delaying properties at clinically relevant concentration.Jun 30, 2012

Patients taking aspirin plus ibuprofen have an increased risk of all-cause mortality.Feb 15, 2003

Patients with hypertension treated with calcium channel blockers have increased incident of heart failure.Jul 15, 2010

Prior aspirin use predicts worse outcomes in patients with non-ST-elevation acute coronary syndromes. Apr 15, 1999

Proton pump inhibitor use represents an independent risk factor for myocardial infarction.Nov 14, 2014

Proton-pump inhibitors seem to be associated with increased risk for adverse cardiovascular outcomes.Sep 21, 2010

Radiofrequency electromagnetic radiation increases parasympathetic nervous system activity.May 01, 2018

Raloxifene is associated with double the risk of coronary artery disease. Jan 01, 2009

Raloxifene therapy increases risk of deep venous thrombosis and pulmonary embolism. Feb 01, 2008

Relationship between urinary bisphenol a levels and cardiovascular diseases in the U.S. adult population.Feb 09, 2020

Rosiglitazone use is associated with an increased risk of acute myocardial infarction in the elderly.Apr 01, 2009

Rosiglitazone use is associated with an increased risk of stroke, heart failure, and all-cause mortality.Jul 28, 2010

Serum fructose is positively correlated with myocardial infarction. Nov 01, 2009

Statin-induced reduction in HDL-C was relatively common and was associated with increased risk of major adverse cardiovascular events.Dec 29, 2015

Sucrose consumption higher than 15% is associated with an increased risk of a coronary events.Oct 23, 2016

TETRA signals alter EEG and electrocardiogram readings consistent with vagal nerve stimulation in the chest.Oct 01, 2016

The combination of Red Bull and mental stress impose a cumulative cardiovascular load and reduces cerebral blood flow.Jan 14, 2015

The consumption of fructose-containing sugar-sweetened beverage is associated with a more atherogenic LDL lipid profile. Jun 15, 2011

The intake of partially hydrogenated vegetable oils may contribute to the risk of myocardial infarction.Jan 01, 1994

The intake of trans fatty acids and risk of coronary heart disease among women.Mar 06, 1993

The radiofrequency of cell phone prolongs the QT interval in human beings and it interferes with voltage criteria of ECG records in male patients with myocardial ischemia.Jul 01, 2012

The use of rofecoxib, valdecoxib, and indomethacin increases the risk of cardiovascular disease.Nov 01, 2009

There is a risk of congenital heart disease in patients who are prenatally exposed to anti-depressant medications.May 14, 2019

These results indicate that exposure to radiofrequency EMF may affect the neurovegetative regulation.Sep 01, 2012

These results showed that even a single can of energy drinks can acutely increase atrial electromechanical conduction times in young adults.Nov 18, 2019

This study supports the association of proton pump inhibitors exposure with risk for myocardial infarction in the general population.Dec 31, 2014

Type 2 diabetic patients patients treated with statin drugs have decreased coq10 levels and may be associated with subclinical diabetic cardiomyopathy reversible by CoQ10 supplementation.Apr 01, 1999

Use of antipsychotic drugs is associated with an increased risk of ventricular arrhythmia and sudden cardiac death.Jan 31, 2015

Use of non-selective NSAIDs was associated with an increased early risk of out-of-hospital cardiac arrest.Dec 25, 2016

Use of proton pump inhibitors is associated with an increase in adverse cardiovascular events in patients with hemodialysis.Nov 13, 2019

Women treated with radiotherapy for breast cancer experience an increased risk of heart disease as a result. Jul 11, 2011

Chronic exposure to PPIs impaired endothelial function and accelerated human endothelial senescence by reducing telomere length.May 09, 2016

Electromagnetic fields alter alkaline phosphatase activity in vitro.Jan 01, 2001

Low doses of BPA induced abnormal mitochondrial fission and hypertrophy in human embryonic stem cell-derived cardiomyocytes.Dec 08, 2019

Cardiotoxic

View the Evidence:
166 Abstracts with Cardiotoxic Research