Chemoresistance upregulation

Name	AC	CK
Adrenaline	3	3
Bisphenol A	2	2
Nicotine	1	2

Name

Focus

Adrenaline

Bisphenol A

Nicotine

Name	AC	CK
Glioblastoma	1	5
Breast Cancer	3	3
Cancers: Drug Resistant	3	3
Bladder Cancer	1	2
Breast Cancer: Triple Negative	1	1
Breast Cancer: estrogen receptor alpha-positive	1	1
Cancers: Multi-Drug Resistant	1	1
Colon Cancer	1	1
Esophageal Cancer	1	1
Squamous cell carcinoma	1	1

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Magnetic fields may upregulate chemoresistance in human glioblastoma.Jan 01, 2018

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Pubmed Data : Electromagn Biol Med. 2018 ;37(3):138-145. Epub 2018 May 30. PMID: 29846098

Article Published Date : Jan 01, 2018

Study Type : Human In Vitro

Additional Links

Diseases : Glioblastoma

Pharmacological Actions : Antineoplastic Agents, Apoptotic

Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation

Adverse Pharmacological Actions : Chemoresistance upregulation

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Nicotine increases tumor growth and induces acquired chemoresistance through activation of the PI3K/Akt/mTOR pathway in bladder cancer.Aug 31, 2015

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Pubmed Data : Mol Cancer Ther. 2015 Sep ;14(9):2112-20. Epub 2015 Jul 16. PMID: 26184482

Article Published Date : Aug 31, 2015

Study Type : Animal Study, In Vitro Study

Additional Links

Diseases : Bladder Cancer

Problem Substances : Nicotine

Adverse Pharmacological Actions : Chemoresistance upregulation

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Adrenaline induces chemoresistance in HT-29 colon adenocarcinoma cells.Apr 15, 2009

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Pubmed Data : Cancer Genet Cytogenet. 2009 Apr 15 ;190(2):81-7. PMID: 19380024

Article Published Date : Apr 15, 2009

Study Type : In Vitro Study

Additional Links

Diseases : Cancers: Drug Resistant, Colon Cancer

Anti Therapeutic Actions : Stress

Problem Substances : Adrenaline

Adverse Pharmacological Actions : Carcinogenic, Chemoresistance upregulation

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BPA and E2 confer resistance against cisplatin, likely through their ability to increase Bcl-2 expression, thereby preventing drug-induced apoptosis.Apr 27, 2010

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cancer Lett. 2010 Apr 28 ;290(2):167-73. Epub 2009 Sep 30. PMID: 19796866

Article Published Date : Apr 27, 2010

Study Type : In Vitro Study

Additional Links

Diseases : Breast Cancer

Additional Keywords : Drug: Cisplatin

Problem Substances : Bisphenol A

Adverse Pharmacological Actions : Chemoresistance upregulation

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BPA at environmentally relevant doses reduces the efficacy of chemotherapeutic agents doxorubicin, cisplatin, and vinblastine.Jan 31, 2009

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Environ Health Perspect. 2009 Feb ;117(2):175-80. Epub 2008 Oct 8. PMID: 19270784

Article Published Date : Jan 31, 2009

Study Type : In Vitro Study

Additional Links

Diseases : Breast Cancer, Breast Cancer: estrogen receptor alpha-positive, Breast Cancer: Triple Negative

Pharmacological Actions : Apoptotic, Estrogen Receptor Modulators

Additional Keywords : Drug: Cisplatin, Drug: Doxorubicin, Drug: Vinblastine

Problem Substances : Bisphenol A

Adverse Pharmacological Actions : Chemoresistance upregulation

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Epinephrine stimulates esophageal squamous-cell carcinoma cell proliferation.Sep 01, 2008

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Pubmed Data : J Cell Biochem. 2008 Sep 1 ;105(1):53-60. PMID: 18452159

Article Published Date : Sep 01, 2008

Study Type : In Vitro Study

Additional Links

Diseases : Cancers: Drug Resistant, Esophageal Cancer, Squamous cell carcinoma

Pharmacological Actions : Antiproliferative , Cyclooxygenase 2 Inhibitors, Vascular Endothelial Growth Factor A Inhibitor

Anti Therapeutic Actions : Stress

Problem Substances : Adrenaline

Adverse Pharmacological Actions : Chemoresistance upregulation

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Psychological stress induces chemoresistance in breast cancer by upregulating mdr1.Apr 15, 2005

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Pubmed Data : Biochem Biophys Res Commun. 2005 Apr 15 ;329(3):888-97. PMID: 15752739

Article Published Date : Apr 15, 2005

Study Type : In Vitro Study

Additional Links

Diseases : Breast Cancer, Cancers: Drug Resistant, Cancers: Multi-Drug Resistant

Pharmacological Actions : Antineoplastic Agents

Anti Therapeutic Actions : Stress

Problem Substances : Adrenaline

Adverse Pharmacological Actions : Chemoresistance upregulation, Multidrug resistance 1 (p-glycoprotein 1) upregulation

Chemoresistance upregulation

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Magnetic fields may upregulate chemoresistance in human glioblastoma.Jan 01, 2018

Click here to read the entire abstract

Nicotine increases tumor growth and induces acquired chemoresistance through activation of the PI3K/Akt/mTOR pathway in bladder cancer.Aug 31, 2015

Click here to read the entire abstract

Adrenaline induces chemoresistance in HT-29 colon adenocarcinoma cells.Apr 15, 2009

Click here to read the entire abstract

BPA and E2 confer resistance against cisplatin, likely through their ability to increase Bcl-2 expression, thereby preventing drug-induced apoptosis.Apr 27, 2010

Click here to read the entire abstract

BPA at environmentally relevant doses reduces the efficacy of chemotherapeutic agents doxorubicin, cisplatin, and vinblastine.Jan 31, 2009

Click here to read the entire abstract

Epinephrine stimulates esophageal squamous-cell carcinoma cell proliferation.Sep 01, 2008

Click here to read the entire abstract

Psychological stress induces chemoresistance in breast cancer by upregulating mdr1.Apr 15, 2005

Click here to read the entire abstract