Estrogen Agonist

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5 Problem Substances Researched for Estrogen Agonist
NameACCKFocus
Tamoxifen211Locked
Hexachlorocyclohexane11Locked
Organochlorine compounds11Locked
Persistent organic pollutants (POPs)11Locked
Polychlorinated biphenyls (PCBs)11Locked
3 Diseases Researched for Estrogen Agonist
NameACCKFocus
Breast Cancer414Locked
Endometrial Cancer211Locked
Endometrial Neoplasms110Locked

View the Evidence:
4 Abstracts with Estrogen Agonist Research

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Tamoxifen treatment for breast cancer results in one-third of all patients developing endometrial polyps, hyperplasia, metaplasia, consistent with an estrogen-agonist effect.Aug 01, 2000

Pubmed Data : Gynecol Oncol. 2000 Aug;78(2):181-6. PMID: 10926800
Article Published Date : Aug 01, 2000
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Endometrial Cancer, Endometrial Neoplasms
Additional Keywords : Drug: Tamoxifen
Problem Substances : Tamoxifen
Adverse Pharmacological Actions : Estrogen Agonist, Estrogenic
[+]

Beta-hexachlorocyclohexane has an estrogenic action in human breast cancer cells.Dec 01, 1996

Pubmed Data : Cancer Res. 1996 Dec 1;56(23):5403-9. PMID: 8968093
Article Published Date : Dec 01, 1996
Study Type : In Vitro Study
Additional Links
Diseases : Breast Cancer
Problem Substances : Hexachlorocyclohexane, Persistent organic pollutants (POPs)
Adverse Pharmacological Actions : Estrogen Agonist, Estrogenic
[+]

Organochlorine pesticide residues may generate an estrogenic pro-carcinogenic microenvironment in adipose mammary tissue.Jan 01, 2006

Pubmed Data : Breast Cancer Res. 2006;8(4):R47. PMID: 16859517
Article Published Date : Jan 01, 2006
Study Type : In Vitro Study
Additional Links
Diseases : Breast Cancer
Problem Substances : Organochlorine compounds, Polychlorinated biphenyls (PCBs)
Adverse Pharmacological Actions : Carcinogenic, Estrogen Agonist
[+]

Tamoxifen has a proliferative effecct against endometrial cancer cells.Sep 01, 2004

Pubmed Data : Oncol Rep. 2004 Sep;12(3):517-21. PMID: 15289830
Article Published Date : Sep 01, 2004
Study Type : In Vitro Study
Additional Links
Diseases : Endometrial Cancer
Additional Keywords : Drug: Tamoxifen
Problem Substances : Tamoxifen
Adverse Pharmacological Actions : Carcinogenic, Estrogen Agonist, Proliferative

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