Excitotoxic

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9 Problem Substances Researched for Excitotoxic

Name	AC	CK
L-glutamic Acid	2	12
Monosodium Glutamate (MSG)	2	12
Cell Phone Exposure	1	10
Glyphosate formulations	1	2
Mercury	2	2
Roundup (herbicide)	1	2
Thimerosal	2	2
Aluminum	1	1
Fluoride	1	1

17 Diseases Researched for Excitotoxic

Name	AC	CK
Amyotrophic Lateral Sclerosis	1	10
Epilepsy	1	10
Brain Inflammation	2	3
Excitotoxicity	2	3
Alzheimer's Disease	1	2
Autism Spectrum Disorders	2	2
Brain: Microglial Activation	2	2
Neurotoxicity	1	2
Oxidative Stress	2	2
Parkinson's Disease	1	2
Parkinsonism	1	2
Autism	1	1
DNA damage	1	1
Endothelial Dysfunction	1	1
Heavy Metal Toxicity	1	1
Lipid Peroxidation	1	1
Mitochondrial Diseases	1	1

Research Articles 10
Cumulative Knowledge Score 16
Overall Research Rating GOOD

View the Evidence:
10 Abstracts with Excitotoxic Research

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Glutamate levels may contribute to the pathogenesis of ALS.Feb 01, 2010

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Pubmed Data : Acta Neurol Scand. 2010 Feb;121(2):120-6. Epub 2009 Oct 5. PMID: 19804473

Article Published Date : Feb 01, 2010

Study Type : Human Study

Additional Links

Diseases : Amyotrophic Lateral Sclerosis

Problem Substances : L-glutamic Acid, Monosodium Glutamate (MSG)

Adverse Pharmacological Actions : Excitotoxic

[+]

Mobiel phones modify brain excitability in humans.Aug 01, 2006

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Pubmed Data : Ann Neurol. 2006 Aug ;60(2):188-96. PMID: 16802289

Article Published Date : Aug 01, 2006

Study Type : Human Study

Additional Links

Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation

Problem Substances : Cell Phone Exposure

Adverse Pharmacological Actions : Excitotoxic, Neurotoxic

[+]

Mobile phone EMFs modulate cortical excitability in patients affected by focal epilepsy.May 01, 2013

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Pubmed Data : Brain Stimul. 2013 May ;6(3):448-54. Epub 2012 Aug 9. PMID: 22889717

Article Published Date : May 01, 2013

Study Type : Human Study

Additional Links

Diseases : Epilepsy

Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation

Adverse Pharmacological Actions : Excitotoxic, Neurotoxic

[+]

Glutamate induces mitochondrial dynamic imbalance and autophagy activation that can be prevented with selenium.Dec 31, 2011

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2012 ;7(6):e39382. Epub 2012 Jun 19. PMID: 22724008

Article Published Date : Dec 31, 2011

Study Type : Animal Study

Additional Links

Substances : Selenium

Diseases : Excitotoxicity

Pharmacological Actions : Neuroprotective Agents

Problem Substances : L-glutamic Acid, Monosodium Glutamate (MSG)

Adverse Pharmacological Actions : Excitotoxic

[+]

MECHANISMS UNDERLYING THE NEUROTOXICITY INDUCED BY GLYPHOSATE-BASED HERBICIDE IN IMMATURE RAT HIPPOCAMPUS: INVOLVEMENT OF GLUTAMATE EXCITOTOXICITY.Mar 13, 2014

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Pubmed Data : Toxicology. 2014 Mar 14. Epub 2014 Mar 14. PMID: 24636977

Article Published Date : Mar 13, 2014

Study Type : Animal Study

Additional Links

Diseases : Alzheimer's Disease, Brain Inflammation , Neurotoxicity, Parkinson's Disease, Parkinsonism

Problem Substances : Glyphosate formulations, Roundup (herbicide)

Adverse Pharmacological Actions : Excitotoxic, Neurotoxic

[+]

Microwave radiation enhances excitability of brain structures and influences bioelectric processes of narcotized rats.Sep 01, 2000

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Pubmed Data : Bull Exp Biol Med. 2000 Sep ;130(9):835-7. PMID: 11177257

Article Published Date : Sep 01, 2000

Study Type : Animal Study

Additional Links

Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation

Adverse Pharmacological Actions : Excitotoxic

[+]

The results of this study suggest that ethylmercury is a mitochondrial toxin in human astrocytes. Dec 31, 2011

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Toxicol. 2012 ;2012:373678. Epub 2012 Jun 28. PMID: 22811707

Article Published Date : Dec 31, 2011

Study Type : In Vitro Study

Additional Links

Diseases : DNA damage, Excitotoxicity , Oxidative Stress

Problem Substances : Thimerosal

Adverse Pharmacological Actions : Apoptotic, Excitotoxic

[+]

These results demonstrate that the oxidation and reduction of thiol residues alters the properties of voltage-sensitive sodium channels and may play an important role in the regulation of membrane excitability.Jan 01, 2000

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Pubmed Data : Neuroscience. 2000 ;101(1):229-36. PMID: 11068151

Article Published Date : Jan 01, 2000

Study Type : In Vitro Study

Additional Links

Additional Keywords : Vaccine Research

Problem Substances : Thimerosal

Adverse Pharmacological Actions : Excitotoxic

[+]

This evidence suggests that mercury may be either causal or contributory in the brain pathology in autism spectrum disorder.Jan 01, 2012

Click here to read the entire abstract

Pubmed Data : Acta Neurobiol Exp (Wars). 2012 ;72(2):113-53. PMID: 22810216

Article Published Date : Jan 01, 2012

Study Type : Review

Additional Links

Diseases : Autism Spectrum Disorders, Brain: Microglial Activation, Brain Inflammation , Endothelial Dysfunction, Lipid Peroxidation, Mitochondrial Diseases, Oxidative Stress

Additional Keywords : Heavy Metals and Autism, Vaccine Research

Problem Substances : Mercury

Adverse Pharmacological Actions : Excitotoxic, Inflammatory, Neurotoxic, Oxidant

[+]

This study suggests that excitotoxicity may be the central mechanism of autism spectrum disorders and that excitotoxins like aluminum, fluoride, and mercury may exacerbate excitotoxicity.Jan 01, 2009

Click here to read the entire abstract

Pubmed Data : Curr Med Chem. 2009 ;16(2):157-70. PMID: 19149568

Article Published Date : Jan 01, 2009

Study Type : Review

Additional Links

Diseases : Autism, Autism Spectrum Disorders, Brain: Microglial Activation, Heavy Metal Toxicity

Additional Keywords : Heavy Metals and Autism, Vaccine Research

Problem Substances : Aluminum, Fluoride, Mercury

Adverse Pharmacological Actions : Excitotoxic, Neurotoxic

Research Articles 10
Cumulative Knowledge Score 16
Overall Research Rating GOOD

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MSG: Delicious Seasoning Or Drug And Poison?

Written by Sayer Ji, Founder

Monosodium glutamate (MSG) is a commonly used "flavor enhancer," and so powerfully so that (arguably) you could spray it on roadkill and it would taste good. This omnipresent ingredient in modern mass market food takes advantage of our biologically hard-wired taste receptors, and makes it very hard to stop eating the foods "seasoned" with this ingredient.

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This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

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Focus Your Research

Click any topic below to filter + focus research

View the Evidence: 10 Abstracts with Excitotoxic Research

Limited to Members Only

Currently Available Sorting Options

Glutamate levels may contribute to the pathogenesis of ALS.Feb 01, 2010

Mobiel phones modify brain excitability in humans.Aug 01, 2006

Mobile phone EMFs modulate cortical excitability in patients affected by focal epilepsy.May 01, 2013

Glutamate induces mitochondrial dynamic imbalance and autophagy activation that can be prevented with selenium.Dec 31, 2011

MECHANISMS UNDERLYING THE NEUROTOXICITY INDUCED BY GLYPHOSATE-BASED HERBICIDE IN IMMATURE RAT HIPPOCAMPUS: INVOLVEMENT OF GLUTAMATE EXCITOTOXICITY.Mar 13, 2014

Microwave radiation enhances excitability of brain structures and influences bioelectric processes of narcotized rats.Sep 01, 2000

The results of this study suggest that ethylmercury is a mitochondrial toxin in human astrocytes. Dec 31, 2011

These results demonstrate that the oxidation and reduction of thiol residues alters the properties of voltage-sensitive sodium channels and may play an important role in the regulation of membrane excitability.Jan 01, 2000

This evidence suggests that mercury may be either causal or contributory in the brain pathology in autism spectrum disorder.Jan 01, 2012

This study suggests that excitotoxicity may be the central mechanism of autism spectrum disorders and that excitotoxins like aluminum, fluoride, and mercury may exacerbate excitotoxicity.Jan 01, 2009

Excitotoxic Related Articles

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Excitotoxic

View the Evidence:
10 Abstracts with Excitotoxic Research