Gastrotoxic

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27 Problem Substances Researched for Gastrotoxic
NameACCKFocus
Aspirin 340Locked
Polystyrene nanoparticles1024Locked
Alendronate (trade name Fosamax) 220Locked
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)220Locked
Glyphosate813Locked
Bisphenol A 611Locked
Omeprazole (trade name Prilosec)110Locked
Pamidronate110Locked
Proton-Pump Inhibitors110Locked
Sodium Fluoride47Locked
Titanium Dioxide24Locked
Artificial Sweeteners23Locked
Ozempic13Locked
Antibiotics12Locked
Antidepressants12Locked
Bisphenol F12Locked
Bisphenol S22Locked
Diclofenac12Locked
High Fructose Corn Syrup12Locked
Nano Plastic-and Micro-Particles12Locked
Phthalates12Locked
Polyethylene12Locked
Polysorbate 8012Locked
Sucralose (aka Splenda)12Locked
Titanium Nanoparticles12Locked
Saccharin11Locked
Sugar Sweetened Beverages11Locked
43 Diseases Researched for Gastrotoxic
NameACCKFocus
Microplastic Toxicity2356Locked
Dysbiosis1641Locked
Chronic Kidney Disease (CKD)120Locked
Drug-Induced Toxicity: Gastrointestinal220Locked
Gastric Ulcer220Locked
Glyphosate Toxicity813Locked
Bisphenol Toxicity712Locked
Inflammation612Locked
Air Pollution Linked Toxicity110Locked
Alzheimer's Disease110Locked
Attention Deficit Hyperactivity Disorder110Locked
Osteoporosis110Locked
Schizophrenia110Locked
Gastrointestinal Inflammation38Locked
Fluoride Toxicity 47Locked
Obesity36Locked
Oxidative Stress36Locked
Gastrointestinal Diseases15Locked
Mucositis15Locked
Anxiety24Locked
Prenatal Chemical Exposures24Locked
Coronavirus Disease (Covid-19)23Locked
Gastroparesis13Locked
Inflammatory Bowel Diseases23Locked
Antibiotic Toxicity 12Locked
Autism Spectrum Disorders12Locked
Chemically-Induced Liver Damage12Locked
Colitis12Locked
Colorectal Cancer22Locked
Crohn's Disease12Locked
DNA damage12Locked
Depression12Locked
Drug-Induced Toxicity: Indomethacin12Locked
Food Allergies12Locked
High Fat Diet12Locked
Infertility: Female12Locked
Mineral Deficiencies: Selenium12Locked
Phthalate Toxicity 12Locked
Titanium Toxicity12Locked
Ulcerative Colitis12Locked
Vitamin D Deficiency12Locked
Breast Cancer: Triple Negative 11Locked
Irritable Bowel Syndrome11Locked

View the Evidence:
65 Abstracts with Gastrotoxic Research

[+]

Aspirin did not prevent CV events, with a significantly increased risk of minor bleeding and renal events.May 29, 2023

Pubmed Data : Curr Vasc Pharmacol. 2023 May 30. Epub 2023 May 30. PMID: 37259222
Article Published Date : May 29, 2023
Study Type : Meta Analysis
Additional Links
Diseases : Chronic Kidney Disease (CKD)
Problem Substances : Aspirin
Adverse Pharmacological Actions : Gastrotoxic
[+]

Alendronate is associated with injury and ulceration of the gastric mucosa. Nov 01, 2000

Pubmed Data : Aliment Pharmacol Ther. 2000 Nov;14(11):1451-7. PMID: 11069316
Article Published Date : Nov 01, 2000
Study Type : Human Study
Additional Links
Diseases : Drug-Induced Toxicity: Gastrointestinal, Gastric Ulcer, Osteoporosis
Problem Substances : Alendronate (trade name Fosamax) , Aspirin , Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
Adverse Pharmacological Actions : Gastrotoxic, Ulcerogenic
[+]

Bisphosphonates cause mucosal injury to the upper gastrointestinal tract similar to aspirin.Aug 01, 1997

Pubmed Data : Am J Gastroenterol. 1997 Aug;92(8):1322-5. PMID: 9260798
Article Published Date : Aug 01, 1997
Study Type : Human Study
Additional Links
Diseases : Drug-Induced Toxicity: Gastrointestinal, Gastric Ulcer
Problem Substances : Alendronate (trade name Fosamax) , Aspirin , Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), Pamidronate
Adverse Pharmacological Actions : Gastrotoxic, Ulcerogenic
[+]

Causal effects of PM2.5 exposure on neuropsychiatric disorders and the mediation via gut microbiota.Mar 31, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ecotoxicol Environ Saf. 2024 Apr 1 ;275:116257. Epub 2024 Apr 1. PMID: 38564871
Article Published Date : Mar 31, 2024
Study Type : Human Study
Additional Links
Diseases : Air Pollution Linked Toxicity, Alzheimer's Disease, Attention Deficit Hyperactivity Disorder, Schizophrenia
Additional Keywords : Risk Factors
Adverse Pharmacological Actions : Gastrotoxic
[+]

Effects of thermal exposure to disposable plastic tableware on human gut microbiota and metabolites.Jan 14, 2024

Pubmed Data : J Hazard Mater. 2024 Jan 15 ;462:132800. Epub 2023 Oct 19. PMID: 37866144
Article Published Date : Jan 14, 2024
Study Type : Human Study
Additional Links
Diseases : Dysbiosis, Microplastic Toxicity
Adverse Pharmacological Actions : Gastrotoxic
[+]

Omeprazole treatment have caused considerable changes in stool culture results.Feb 28, 2017

Pubmed Data : Clin Res Hepatol Gastroenterol. 2017 Mar 1. Epub 2017 Mar 1. PMID: 28258834
Article Published Date : Feb 28, 2017
Study Type : Human Study
Additional Links
Additional Keywords : Risk Factors
Problem Substances : Omeprazole (trade name Prilosec), Proton-Pump Inhibitors
Adverse Pharmacological Actions : Gastrotoxic
[+]

Nano-plastics and gastric health: Decoding the cytotoxic mechanisms of polystyrene nano-plastics size.Dec 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Int. 2024 Jan ;183:108380. Epub 2023 Dec 11. PMID: 38141489
Article Published Date : Dec 31, 2023
Study Type : Human In Vitro
Additional Links
Diseases : Gastrointestinal Diseases, Microplastic Toxicity
Problem Substances : Polystyrene nanoparticles
Adverse Pharmacological Actions : Gastrotoxic
[+]

This study identifies profound disruption of the intestinal microbiome in terms of both taxonomic composition and metabolic capacity after chemotherapy.Jul 05, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Aliment Pharmacol Ther. 2015 Jul 6. Epub 2015 Jul 6. PMID: 26147207
Article Published Date : Jul 05, 2015
Study Type : Human In Vitro
Additional Links
Diseases : Dysbiosis, Gastrointestinal Inflammation, Mucositis
Additional Keywords : Microbiota
Anti Therapeutic Actions : Chemotherapy
Adverse Pharmacological Actions : Gastrotoxic
[+]

Melatonin attenuates bisphenol A-induced colon injury.Jan 31, 2023

Pubmed Data : Free Radic Biol Med. 2023 Feb 1 ;195:13-22. Epub 2022 Dec 19. PMID: 36549428
Article Published Date : Jan 31, 2023
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Melatonin
Diseases : Bisphenol Toxicity
Pharmacological Actions : Antioxidants, Gastroprotective, Nrf2 activation
Problem Substances : Bisphenol A
Adverse Pharmacological Actions : Gastrotoxic
[+]

Polystyrene nanoparticles induced mammalian intestine damage caused by blockage of BNIP3/NIX-mediated mitophagy and gut microbiota alteration.Jan 09, 2024

Pubmed Data : Sci Total Environ. 2024 Jan 10 ;907:168064. Epub 2023 Oct 24. PMID: 37884137
Article Published Date : Jan 09, 2024
Study Type : Animal Study, In Vitro Study
Additional Links
Diseases : Microplastic Toxicity
Problem Substances : Polystyrene nanoparticles
Adverse Pharmacological Actions : Gastrotoxic
[+]

Tendency of semaglutide to induce gastroparesis: A case report. Dec 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cureus. 2024 Jan ;16(1):e52564. Epub 2024 Jan 19. PMID: 38371020
Article Published Date : Dec 31, 2023
Study Type : Human: Case Report
Additional Links
Diseases : Gastroparesis
Additional Keywords : Risk Factors
Problem Substances : Ozempic
Adverse Pharmacological Actions : Gastrotoxic
[+]

Adverse effects of titanium dioxide nanoparticles on beneficial gut bacteria.Jun 30, 2023

Pubmed Data : Environ Res. 2023 Jul 1 ;228:115921. Epub 2023 Apr 15. PMID: 37068726
Article Published Date : Jun 30, 2023
Study Type : Animal Study
Additional Links
Diseases : Titanium Toxicity
Problem Substances : Titanium Dioxide
Adverse Pharmacological Actions : Gastrotoxic
[+]

Antibiotic-induced gut microbiota dysbiosis damages the intestinal barrier, increasing food allergy.Sep 22, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2021 Sep 23 ;13(10). Epub 2021 Sep 23. PMID: 34684316
Article Published Date : Sep 22, 2021
Study Type : Animal Study
Additional Links
Diseases : Antibiotic Toxicity , Dysbiosis, Food Allergies, Inflammation
Additional Keywords : Increased Risk
Problem Substances : Antibiotics
Adverse Pharmacological Actions : Gastrotoxic
[+]

Chronic exposure to polystyrene nanoplastics induces intestinal mechanical and immune barrier dysfunction in mice.Nov 29, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ecotoxicol Environ Saf. 2023 Nov 30 ;269:115749. Epub 2023 Nov 30. PMID: 38039854
Article Published Date : Nov 29, 2023
Study Type : Animal Study
Additional Links
Diseases : Inflammation, Microplastic Toxicity
Problem Substances : Polystyrene nanoparticles
Adverse Pharmacological Actions : Gastrotoxic, Inflammatory
[+]

Combined exposure to microplastics and amitriptyline caused intestinal damage, oxidative stress and gut microbiota dysbiosis.Jun 30, 2023

Pubmed Data : Aquat Toxicol. 2023 Jul ;260:106589. Epub 2023 May 24. PMID: 37245408
Article Published Date : Jun 30, 2023
Study Type : Animal Study
Additional Links
Diseases : Dysbiosis, Microplastic Toxicity, Oxidative Stress
Pharmacological Actions : Gastrointestinal Agents
Problem Substances : Antidepressants
Adverse Pharmacological Actions : Gastrotoxic
[+]

Developmental vitamin D-deficiency produces autism-relevant behaviours and gut-health associated alterations.Jun 13, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Transl Psychiatry. 2023 Jun 14 ;13(1):204. Epub 2023 Jun 14. PMID: 37316481
Article Published Date : Jun 13, 2023
Study Type : Animal Study
Additional Links
Substances : Vitamin D
Diseases : Autism Spectrum Disorders, Vitamin D Deficiency
Pharmacological Actions : Gastrointestinal Agents
Adverse Pharmacological Actions : Gastrotoxic
[+]

Di-(2-ethylhexyl) phthalate exposure induces female reproductive toxicity.Mar 03, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Toxicol. 2021 Mar 4. Epub 2021 Mar 4. PMID: 33665894
Article Published Date : Mar 03, 2021
Study Type : Animal Study
Additional Links
Diseases : Infertility: Female, Phthalate Toxicity
Problem Substances : Phthalates
Adverse Pharmacological Actions : Gastrotoxic
[+]

Dietary emulsifier polysorbate-80 induces small-intestinal vulnerability to indomethacin-induced lesions via dysbiosis.Jul 28, 2019

Pubmed Data : J Gastroenterol Hepatol. 2019 Jul 29. Epub 2019 Jul 29. PMID: 31359491
Article Published Date : Jul 28, 2019
Study Type : Animal Study
Additional Links
Diseases : Drug-Induced Toxicity: Indomethacin, Dysbiosis
Problem Substances : Polysorbate 80
Adverse Pharmacological Actions : Gastrotoxic
[+]

Differently surface-labeled polystyrene nanoplastics at an environmentally relevant concentration induced Crohn's ileitis-like features.May 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Int. 2023 Jun ;176:107968. Epub 2023 May 12. PMID: 37201399
Article Published Date : May 31, 2023
Study Type : Animal Study
Additional Links
Diseases : Crohn's Disease, Microplastic Toxicity
Problem Substances : Polystyrene nanoparticles
Adverse Pharmacological Actions : Gastrotoxic
[+]

Effects of bisphenol A and its substitute, bisphenol F, on the gut microbiota in mice.Jan 19, 2024

Pubmed Data : Biomed Environ Sci. 2024 Jan 20 ;37(1):19-30. PMID: 38326718
Article Published Date : Jan 19, 2024
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity
Problem Substances : Bisphenol A , Bisphenol F
Adverse Pharmacological Actions : Gastrotoxic
[+]

Effects of partial reduction of polystyrene micro-nanoplastics on the immunity, gut microbiota and metabolome of mice.Dec 12, 2023

Pubmed Data : Chemosphere. 2023 Dec 13 ;349:140940. Epub 2023 Dec 13. PMID: 38101478
Article Published Date : Dec 12, 2023
Study Type : Animal Study
Additional Links
Diseases : Microplastic Toxicity
Adverse Pharmacological Actions : Gastrotoxic, Immunotoxic
[+]

Exposure to microplastics impairs digestive performance, stimulates immune response and induces microbiota dysbiosis.Aug 31, 2020

Pubmed Data : Sci Total Environ. 2020 Sep 1 ;733:138929. Epub 2020 May 6. PMID: 32466972
Article Published Date : Aug 31, 2020
Study Type : Animal Study
Additional Links
Diseases : Dysbiosis, Microplastic Toxicity
Adverse Pharmacological Actions : Gastrotoxic, Immunotoxic
[+]

Fluoride exposure cause colon microbiota dysbiosis by destroyed microenvironment and disturbed antimicrobial peptides expression in colon.Dec 31, 2021

Pubmed Data : Environ Pollut. 2022 Jan 1 ;292(Pt B):118381. Epub 2021 Oct 18. PMID: 34673156
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Diseases : Dysbiosis, Fluoride Toxicity
Problem Substances : Sodium Fluoride
Adverse Pharmacological Actions : Gastrotoxic
[+]

Glyphosate exposure induces inflammatory responses in the small intestine and alters gut microbial composition in rats.Feb 02, 2020

Pubmed Data : Environ Pollut. 2020 Feb 3 ;261:114129. Epub 2020 Feb 3. PMID: 32045792
Article Published Date : Feb 02, 2020
Study Type : Animal Study
Additional Links
Diseases : Gastrointestinal Inflammation, Glyphosate Toxicity
Problem Substances : Glyphosate
Adverse Pharmacological Actions : Gastrotoxic
[+]

High fat diet disrupts diurnal interactions between small intestinal host innate immune factor REG3γ and gut microbiota resulting in metabolic dysfunction.Apr 30, 2022

Pubmed Data : FASEB J. 2022 May ;36 Suppl 1. PMID: 35556455
Article Published Date : Apr 30, 2022
Study Type : Animal Study
Additional Links
Diseases : High Fat Diet
Adverse Pharmacological Actions : Gastrotoxic
[+]

High-fructose corn syrup aggravates colitis via microbiota dysbiosis-mediated Th17/Treg imbalance.Oct 30, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Sci (Lond). 2023 Oct 31 ;137(20):1619-1635. PMID: 37818653
Article Published Date : Oct 30, 2023
Study Type : Animal Study
Additional Links
Diseases : Colitis, Inflammation, Inflammatory Bowel Diseases
Problem Substances : High Fructose Corn Syrup
Adverse Pharmacological Actions : Gastrotoxic
[+]

Lifelong exposure to a low-dose of the glyphosate-based herbicide RoundUp causes intestinal damage, gut dysbiosis, and behavioral changes.May 16, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2022 May 17 ;23(10). Epub 2022 May 17. PMID: 35628394
Article Published Date : May 16, 2022
Study Type : Animal Study
Additional Links
Diseases : Dysbiosis, Glyphosate Toxicity
Problem Substances : Glyphosate
Adverse Pharmacological Actions : Gastrotoxic, Neurotoxic
[+]

Long-term exposure to environmentally relevant doses of large polystyrene microplastics disturbs lipid homeostasis.Nov 14, 2022

Pubmed Data : Environ Sci Technol. 2022 Nov 15 ;56(22):15805-15817. Epub 2022 Oct 25. PMID: 36282942
Article Published Date : Nov 14, 2022
Study Type : Animal Study
Additional Links
Diseases : Inflammation, Microplastic Toxicity, Obesity
Adverse Pharmacological Actions : Gastrotoxic
[+]

Low-dose exposure of glyphosate-based herbicides disrupt the urine metabolome and its interaction with gut microbiota.Feb 04, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2021 Feb 5 ;11(1):3265. Epub 2021 Feb 5. PMID: 33547360
Article Published Date : Feb 04, 2021
Study Type : Animal Study
Additional Links
Diseases : Glyphosate Toxicity
Problem Substances : Glyphosate
Adverse Pharmacological Actions : Gastrotoxic
[+]

Low-dose glyphosate exposure alters gut microbiota composition and modulates gut homeostasis.May 31, 2023

Pubmed Data : Environ Toxicol Pharmacol. 2023 Jun ;100:104149. Epub 2023 May 15. PMID: 37196884
Article Published Date : May 31, 2023
Study Type : Animal Study
Additional Links
Diseases : Dysbiosis, Glyphosate Toxicity
Problem Substances : Glyphosate
Adverse Pharmacological Actions : Gastrotoxic
[+]

Luteolin may be a promising lead for the treatment of drug-induced gastroenteropathy.Aug 04, 2020

Pubmed Data : Drug Chem Toxicol. 2020 Aug 5:1-13. Epub 2020 Aug 5. PMID: 32757682
Article Published Date : Aug 04, 2020
Study Type : Animal Study
Additional Links
Substances : Luteolin
Diseases : Fluoride Toxicity
Pharmacological Actions : Gastroprotective
Additional Keywords : Synergistic Toxicity
Problem Substances : Diclofenac, Sodium Fluoride
Adverse Pharmacological Actions : Gastrotoxic
[+]

Melatonin alleviates intestinal barrier damaging effects induced by polyethylene microplastics.Sep 02, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2023 Sep 3 ;24(17). Epub 2023 Sep 3. PMID: 37686424
Article Published Date : Sep 02, 2023
Study Type : Animal Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Microplastic
Problem Substances : Polyethylene
Adverse Pharmacological Actions : Gastrotoxic
[+]

Nano- and micro-polystyrene plastics interfered the gut barrier function mediated by exosomal miRNAs in rats.Oct 14, 2023

Pubmed Data : Environ Pollut. 2023 Oct 15 ;335:122275. Epub 2023 Jul 31. PMID: 37532218
Article Published Date : Oct 14, 2023
Study Type : Animal Study
Additional Links
Diseases : Microplastic Toxicity
Problem Substances : Polystyrene nanoparticles
Adverse Pharmacological Actions : Gastrotoxic
[+]

Oral exposure to food grade titanium dioxide (E171) induces intestinal and behavioural alterations in adult mice.Feb 04, 2024

Pubmed Data : J Trace Elem Med Biol. 2024 Feb 5 ;83:127409. Epub 2024 Feb 5. PMID: 38394968
Article Published Date : Feb 04, 2024
Study Type : Animal Study
Additional Links
Diseases : Anxiety, Depression
Problem Substances : Titanium Dioxide
Adverse Pharmacological Actions : Gastrotoxic
[+]

Oral exposure to titanium dioxide nanoparticles for 90 days could disrupt the metabolism of the intestine and gut microbiota.Jun 17, 2020

Pubmed Data : Beijing Da Xue Xue Bao Yi Xue Ban. 2020 Jun 18 ;52(3):457-463. PMID: 32541978
Article Published Date : Jun 17, 2020
Study Type : Animal Study
Additional Links
Diseases : Dysbiosis
Problem Substances : Titanium Nanoparticles
Adverse Pharmacological Actions : Gastrotoxic
[+]

Perinatal exposure to high concentration glyphosate-based herbicides induces intestinal apoptosis by activating endoplasmic reticulum stress in offspring.Mar 19, 2023

Pubmed Data : Sci Total Environ. 2023 Mar 20 ;865:161223. Epub 2022 Dec 28. PMID: 36584959
Article Published Date : Mar 19, 2023
Study Type : Animal Study
Additional Links
Diseases : Glyphosate Toxicity, Prenatal Chemical Exposures
Problem Substances : Glyphosate
Adverse Pharmacological Actions : Gastrotoxic
[+]

Polystyrene micro and nano-particles induce metabolic rewiring in normal human colon cells.Aug 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Chemosphere. 2022 Sep ;303(Pt 1):134947. Epub 2022 May 14. PMID: 35580641
Article Published Date : Aug 31, 2022
Study Type : Animal Study
Additional Links
Diseases : Microplastic Toxicity
Problem Substances : Polystyrene nanoparticles
Adverse Pharmacological Actions : Gastrotoxic
[+]

Polystyrene micro- and nanoparticles exposure induced anxiety-like behaviors, gut microbiota dysbiosis and metabolism disorder in adult mice.Jun 30, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ecotoxicol Environ Saf. 2023 Jul 1 ;259:115000. Epub 2023 May 19. PMID: 37210994
Article Published Date : Jun 30, 2023
Study Type : Animal Study
Additional Links
Diseases : Anxiety, Dysbiosis, Microplastic Toxicity
Adverse Pharmacological Actions : Gastrotoxic
[+]

Polystyrene micro- and nanoplastics induce gastric toxicity.Dec 12, 2023

Pubmed Data : Sci Total Environ. 2023 Dec 13 ;912:169228. Epub 2023 Dec 13. PMID: 38101634
Article Published Date : Dec 12, 2023
Study Type : Animal Study
Additional Links
Diseases : Microplastic Toxicity, Oxidative Stress
Problem Substances : Polystyrene nanoparticles
Adverse Pharmacological Actions : Gastrotoxic
[+]

Polystyrene micro-/nanoplastics induced hematopoietic damages via the crosstalk of gut microbiota, metabolites, and cytokines.Feb 28, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Int. 2022 Mar ;161:107131. Epub 2022 Feb 8. PMID: 35149446
Article Published Date : Feb 28, 2022
Study Type : Animal Study
Additional Links
Diseases : Inflammation, Microplastic Toxicity
Problem Substances : Polystyrene nanoparticles
Adverse Pharmacological Actions : Gastrotoxic
[+]

Polystyrene microplastics trigger adiposity in mice by remodeling gut microbiota and boosting fatty acid synthesis.Sep 09, 2023

Pubmed Data : Sci Total Environ. 2023 Sep 10 ;890:164297. Epub 2023 May 19. PMID: 37211133
Article Published Date : Sep 09, 2023
Study Type : Animal Study
Additional Links
Diseases : Microplastic Toxicity, Obesity
Problem Substances : Polystyrene nanoparticles
Adverse Pharmacological Actions : Gastrotoxic
[+]

Polystyrene nanoplastics shape microbiome and functional metabolism in anaerobic digestion.Jun 30, 2022

Pubmed Data : Water Res. 2022 Jul 1 ;219:118606. Epub 2022 May 14. PMID: 35597220
Article Published Date : Jun 30, 2022
Study Type : Animal Study
Additional Links
Diseases : Microplastic Toxicity
Problem Substances : Polystyrene nanoparticles
Adverse Pharmacological Actions : Gastrotoxic
[+]

Polyvinyl chloride microplastics induced gut barrier dysfunction, microbiota dysbiosis and metabolism disorder in adult mice.Jul 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ecotoxicol Environ Saf. 2022 Aug ;241:113809. Epub 2022 Jul 4. PMID: 36068740
Article Published Date : Jul 31, 2022
Study Type : Animal Study
Additional Links
Diseases : Dysbiosis, Microplastic Toxicity
Adverse Pharmacological Actions : Gastrotoxic
[+]

Polyvinyl chloride microplastics induced gut barrier dysfunction, microbiota dysbiosis and metabolism disorder in adult mice.Mar 31, 2020

Pubmed Data : Chemosphere. 2020 Apr ;244:125492. Epub 2019 Nov 27. PMID: 31809927
Article Published Date : Mar 31, 2020
Study Type : Animal Study
Additional Links
Diseases : Dysbiosis, Inflammation, Microplastic Toxicity
Adverse Pharmacological Actions : Gastrotoxic
[+]

Prenatal BPA exposure may significantly affect offspring's physiological parameters and intestinal function.Jun 07, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2022 Jun 8 ;14(12). Epub 2022 Jun 8. PMID: 35745112
Article Published Date : Jun 07, 2022
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity, Obesity, Prenatal Chemical Exposures
Problem Substances : Bisphenol A
Adverse Pharmacological Actions : Gastrotoxic
[+]

SARS-Cov-2 spike induces intestinal barrier dysfunction through the interaction between CEACAM5 and Galectin-9.Dec 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Immunol. 2024 ;15:1303356. Epub 2024 Apr 15. PMID: 38686388
Article Published Date : Dec 31, 2023
Study Type : Animal Study
Additional Links
Diseases : Coronavirus Disease (Covid-19)
Additional Keywords : SARS-CoV-2 Spike Protein
Adverse Pharmacological Actions : Gastrotoxic
[+]

Selenium deficiency exacerbated Bisphenol A-induced intestinal toxicity.Dec 28, 2023

Pubmed Data : Sci Total Environ. 2023 Dec 29:169730. Epub 2023 Dec 29. PMID: 38160834
Article Published Date : Dec 28, 2023
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity, Mineral Deficiencies: Selenium
Problem Substances : Bisphenol A
Adverse Pharmacological Actions : Gastrotoxic
[+]

Size-dependent toxicity of polystyrene microplastics on the gastrointestinal tract.Feb 19, 2024

Pubmed Data : Sci Total Environ. 2024 Feb 20 ;912:169514. Epub 2023 Dec 20. PMID: 38135073
Article Published Date : Feb 19, 2024
Study Type : Animal Study
Additional Links
Diseases : DNA damage, Oxidative Stress
Adverse Pharmacological Actions : Gastrotoxic
[+]

Sucralose enhances the susceptibility to dextran sulfate sodium (DSS) induced colitis.Oct 03, 2021

Pubmed Data : Food Funct. 2021 Oct 4 ;12(19):9380-9390. Epub 2021 Oct 4. PMID: 34606537
Article Published Date : Oct 03, 2021
Study Type : Animal Study
Additional Links
Diseases : Ulcerative Colitis
Problem Substances : Artificial Sweeteners, Sucralose (aka Splenda)
Adverse Pharmacological Actions : Gastrotoxic
[+]

The dose-response effect of fluoride exposure on the gut microbiome.Nov 16, 2023

Pubmed Data : Metabolites. 2023 Nov 17 ;13(11). Epub 2023 Nov 17. PMID: 37999254
Article Published Date : Nov 16, 2023
Study Type : Animal Study
Additional Links
Diseases : Fluoride Toxicity
Problem Substances : Sodium Fluoride
Adverse Pharmacological Actions : Gastrotoxic
[+]

The impact of microplastics polystyrene on the microscopic structure of mouse intestine, tight junction genes and gut microbiota.Dec 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2024 ;19(6):e0304686. Epub 2024 Jun 5. PMID: 38837998
Article Published Date : Dec 31, 2023
Study Type : Animal Study
Additional Links
Diseases : Dysbiosis, Microplastic Toxicity
Problem Substances : Nano Plastic-and Micro-Particles
Adverse Pharmacological Actions : Gastrotoxic
[+]

Toxicity of polystyrene nanoplastics in the liver and intestine.Oct 17, 2023

Pubmed Data : Environ Toxicol Chem. 2023 Oct 18. Epub 2023 Oct 18. PMID: 37850736
Article Published Date : Oct 17, 2023
Study Type : Animal Study
Additional Links
Diseases : Chemically-Induced Liver Damage, Microplastic Toxicity
Adverse Pharmacological Actions : Dyslipidemic, Gastrotoxic
[+]

Underestimated health risks: polystyrene micro- and nanoplastics jointly induce intestinal barrier dysfunction.Jun 06, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Part Fibre Toxicol. 2021 Jun 7 ;18(1):20. Epub 2021 Jun 7. PMID: 34098985
Article Published Date : Jun 06, 2021
Study Type : Animal Study
Additional Links
Diseases : Microplastic Toxicity
Adverse Pharmacological Actions : Gastrotoxic
[+]

Bisphenol S exposure induces intestinal inflammation.Dec 30, 2021

Pubmed Data : Chemosphere. 2021 Dec 31 ;292:133510. Epub 2021 Dec 31. PMID: 34979203
Article Published Date : Dec 30, 2021
Study Type : In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity, Gastrointestinal Inflammation
Problem Substances : Bisphenol S
Adverse Pharmacological Actions : Gastrotoxic
[+]

BPS is not safe for the innervation of the gastrointestinal tract.Jan 05, 2023

Pubmed Data : Sci Rep. 2023 Jan 6 ;13(1):331. Epub 2023 Jan 6. PMID: 36609592
Article Published Date : Jan 05, 2023
Study Type : In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity
Problem Substances : Bisphenol A , Bisphenol S
Adverse Pharmacological Actions : Gastrotoxic
[+]

Could microplastics be a driver for early onset colorectal cancer?Jun 23, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancers (Basel). 2023 Jun 24 ;15(13). Epub 2023 Jun 24. PMID: 37444433
Article Published Date : Jun 23, 2023
Study Type : Review
Additional Links
Diseases : Colorectal Cancer, Microplastic Toxicity
Adverse Pharmacological Actions : Gastrotoxic
[+]

Does fluoride exposure impact on the human microbiome?Apr 14, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Toxicol Lett. 2023 Apr 15 ;379:11-19. Epub 2023 Mar 4. PMID: 36871794
Article Published Date : Apr 14, 2023
Study Type : Review
Additional Links
Diseases : Fluoride Toxicity
Problem Substances : Sodium Fluoride
Adverse Pharmacological Actions : Gastrotoxic
[+]

Ginger volatile oil inhibits the growth of MDA-MB-231 in the bisphenol A environment by altering gut microbial diversity.Jan 29, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Heliyon. 2024 Jan 30 ;10(2):e24388. Epub 2024 Jan 9. PMID: 38298688
Article Published Date : Jan 29, 2024
Study Type : In Vitro Study
Additional Links
Substances : Ginger
Diseases : Bisphenol Toxicity, Breast Cancer: Triple Negative
Pharmacological Actions : Antiproliferative , Gastrointestinal Agents
Problem Substances : Bisphenol A
Adverse Pharmacological Actions : Gastrotoxic
[+]

Glyphosate: Impact on the microbiota-gut-brain axis and the immune-nervous system, and clinical cases of multiorgan toxicity.Jan 31, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ecotoxicol Environ Saf. 2024 Feb ;271:115965. Epub 2024 Jan 19. PMID: 38244513
Article Published Date : Jan 31, 2024
Study Type : Review
Additional Links
Diseases : Glyphosate Toxicity
Additional Keywords : Gut-brain Axis
Problem Substances : Glyphosate
Adverse Pharmacological Actions : Gastrotoxic, Immunotoxic
[+]

Impact of glyphosate (RoundupTM) on the composition and functionality of the gut microbiome.Nov 30, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Gut Microbes. 2023 Dec ;15(2):2263935. Epub 2023 Oct 6. PMID: 38099711
Article Published Date : Nov 30, 2023
Study Type : Review
Additional Links
Diseases : Dysbiosis, Glyphosate Toxicity
Problem Substances : Glyphosate
Adverse Pharmacological Actions : Gastrotoxic
[+]

Microplastics and the gut microbiome: How chronically exposed species may suffer from gut dysbiosis.May 31, 2019

Pubmed Data : Mar Pollut Bull. 2019 Jun ;143:193-203. Epub 2019 Apr 28. PMID: 31789155
Article Published Date : May 31, 2019
Study Type : Review
Additional Links
Diseases : Dysbiosis, Microplastic Toxicity
Adverse Pharmacological Actions : Gastrotoxic
[+]

Saccharin consumption may potentially alter the intestinal integrity in humans.Jun 24, 2018

Pubmed Data : Food Funct. 2018 Jun 25. Epub 2018 Jun 25. PMID: 29938270
Article Published Date : Jun 24, 2018
Study Type : In Vitro Study
Additional Links
Problem Substances : Artificial Sweeteners, Saccharin
Adverse Pharmacological Actions : Gastrotoxic
[+]

SARS-CoV-2 Spike protein triggers gut impairment since mucosal barrier to innermost layers.Mar 28, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mucosal Immunol. 2024 Mar 29. Epub 2024 Mar 29. PMID: 38555027
Article Published Date : Mar 28, 2024
Study Type : In Vitro Study
Additional Links
Diseases : Coronavirus Disease (Covid-19)
Additional Keywords : SARS-CoV-2 Spike Protein
Adverse Pharmacological Actions : Gastrotoxic
[+]

These results demonstrate that more than one-half of human microbiome are intrinsically sensitive to glyphosate.May 08, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Life (Basel). 2022 May 9 ;12(5). Epub 2022 May 9. PMID: 35629374
Article Published Date : May 08, 2022
Study Type : Review
Additional Links
Diseases : Glyphosate Toxicity
Problem Substances : Glyphosate
Adverse Pharmacological Actions : Gastrotoxic
[+]

Ultra-processed foods and food additives in gut health and disease.Feb 21, 2024

Pubmed Data : Nat Rev Gastroenterol Hepatol. 2024 Feb 22. Epub 2024 Feb 22. PMID: 38388570
Article Published Date : Feb 21, 2024
Study Type : Review
Additional Links
Diseases : Colorectal Cancer, Inflammatory Bowel Diseases, Irritable Bowel Syndrome
Additional Keywords : Ultra-Processed Food
Problem Substances : Sugar Sweetened Beverages
Adverse Pharmacological Actions : Gastrotoxic

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