Interleukin-6 up-regulation

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10 Problem Substances Researched for Interleukin-6 up-regulation
NameACCKFocus
Cell Phone Exposure15Locked
Mercury15Locked
Arsenic12Locked
Brevetoxin12Locked
Fluoride12Locked
Lead12Locked
Red tide12Locked
Simvastatin12Locked
Statin Drugs12Locked
Sodium Fluoride11Locked
27 Diseases Researched for Interleukin-6 up-regulation
NameACCKFocus
Vaccine-induced Toxicity 220Locked
Inflammation316Locked
CRP110Locked
Elevated CRP110Locked
Emotional Disorders110Locked
Pre-Eclampsia110Locked
Pregnancy Complications110Locked
Pregnancy: Vaccination110Locked
Preterm Birth: Prevention 110Locked
Brain Inflammation 27Locked
Autism15Locked
Autism Spectrum Disorders15Locked
Brain: Microglial Activation15Locked
Allergies12Locked
Alzheimer's Disease12Locked
Amyotrophic Lateral Sclerosis12Locked
Cardiovascular Diseases12Locked
DNA damage12Locked
Lead Poisoning12Locked
Mast Cell: Over-Active12Locked
Multiple Sclerosis12Locked
Myopathy12Locked
Oxidative Stress12Locked
Red Tide Associated Toxicity12Locked
Statin-Induced Pathologies12Locked
Chemically-Induced Liver Damage11Locked
Fluoride Toxicity 11Locked

View the Evidence:
10 Abstracts with Interleukin-6 up-regulation Research

[+]

Flu vaccination causes measurable increases in inflammation in pregnant women which may increase the risk of preeclempsia and adverse outcomes such as preterm birth. Sep 20, 2011

Pubmed Data : Vaccine. 2011 Sep 20. Epub 2011 Sep 20. PMID: 21945263
Article Published Date : Sep 20, 2011
Study Type : Human Study
Additional Links
Diseases : CRP, Elevated CRP, Pre-Eclampsia, Pregnancy: Vaccination, Pregnancy Complications, Preterm Birth: Prevention , Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: All, Vaccination: Influenza
Adverse Pharmacological Actions : Interleukin-6 up-regulation, Tumor necrosis factorα (TNFα) up-regulation
[+]

Systemic low-grade inflammation after vaccination impairs emotional recognition.Jan 10, 2018

Pubmed Data : Brain Behav Immun. 2018 10 ;73:216-221. Epub 2018 May 6. PMID: 29742460
Article Published Date : Jan 10, 2018
Study Type : Human Study
Additional Links
Diseases : Emotional Disorders, Inflammation, Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: All
Adverse Pharmacological Actions : Interleukin-6 up-regulation
[+]

1800 MHz radiofrequency fields stimulates pro-inflammatory responses in microglia and astrocytes in vitro.Jan 01, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2014 ;9(9):e108318. Epub 2014 Oct 2. PMID: 25275372
Article Published Date : Jan 01, 2014
Study Type : Human In Vitro
Additional Links
Diseases : Brain: Microglial Activation, Inflammation
Additional Keywords : Brain Function, Brain Inflammation, Cell Phones, electromagnetic fields, electromagnetic frequencies, electromagnetic radiation, EMF
Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation, Electromagnetic Radiation: 1.8 GHz, Microwave Radiation, Mobile Phone Radiation
Problem Substances : Cell Phone Exposure
Adverse Pharmacological Actions : Cycloogenase-2 enzyme upregulation, Inflammatory, Interleukin-1 up-regulation, Interleukin-6 up-regulation, Prostaglandin E2 up-regulation, Tumor necrosis factorα (TNFα) up-regulation
[+]

Mercury stimulates VEGF and IL-6 release from human mast cells which could disrupt the blood-brain-barrier and permit brain inflammation.Mar 11, 2010

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Neuroinflammation. 2010 Mar 11 ;7:20. Epub 2010 Mar 11. PMID: 20222982
Article Published Date : Mar 11, 2010
Study Type : Human In Vitro
Additional Links
Diseases : Autism, Autism Spectrum Disorders, Brain Inflammation
Additional Keywords : Blood Brain Barrier, Heavy Metals and Autism, Vaccine Research
Problem Substances : Mercury
Adverse Pharmacological Actions : Blood Brain Barrier Injury, Inflammatory, Interleukin-6 up-regulation, Vascular Endothelial Growth Factor C Up-Regulation
[+]

Fluoride and arsenic exhibit cardiotoxic properties related to their pro-inflammatory effect.Mar 16, 2012

Pubmed Data : Arch Toxicol. 2012 Mar 16. Epub 2012 Mar 16. PMID: 22422340
Article Published Date : Mar 16, 2012
Study Type : Animal Study
Additional Links
Diseases : Cardiovascular Diseases
Problem Substances : Arsenic, Fluoride
Adverse Pharmacological Actions : Cardiotoxic, Inflammatory, Interleukin-6 up-regulation, Interleukin-8 up-regulation, MCP-1 (CCL2) up-regulation, P-selectin upregulation, Vascular Cell Adhesion Molecule-1 (VCAM-1) Up-Regulation
[+]

Lead may contribute to the pathogenesis of nervous system diseases by stimulating the production of autoantibodies against neural proteins including myelin basic protein.Dec 01, 1994

Pubmed Data : Environ Health Perspect. 1994 Dec;102(12):1052-6. PMID: 7536156
Article Published Date : Dec 01, 1994
Study Type : Animal Study
Additional Links
Diseases : Alzheimer's Disease, Amyotrophic Lateral Sclerosis, Lead Poisoning, Multiple Sclerosis
Problem Substances : Lead
Adverse Pharmacological Actions : Immunotoxic, Interleukin-6 up-regulation
[+]

Marine brevetoxin induces IgE-independent mast cell activation.Feb 01, 2011

Pubmed Data : Arch Toxicol. 2011 Feb ;85(2):135-41. Epub 2010 Jun 13. PMID: 20549194
Article Published Date : Feb 01, 2011
Study Type : Animal Study
Additional Links
Diseases : Allergies, Mast Cell: Over-Active, Red Tide Associated Toxicity
Problem Substances : Brevetoxin, Red tide
Adverse Pharmacological Actions : Interleukin-6 up-regulation, Mast cell degranulation stimulator
[+]

Simvastatin altered gene targets known to be implicated in proteasomal and lysosomal mediated muscle proteolysis, carbohydrate oxidation, oxidative stress and inflammation.Jan 14, 2009

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Physiol. 2009 Jan 15 ;587(Pt 1):219-30. Epub 2008 Nov 10. PMID: 19001041
Article Published Date : Jan 14, 2009
Study Type : Animal Study
Additional Links
Diseases : Myopathy, Statin-Induced Pathologies
Additional Keywords : Gene Expression
Problem Substances : Simvastatin, Statin Drugs
Adverse Pharmacological Actions : Inflammatory, Interleukin-6 up-regulation, Tumor necrosis factorα (TNFα) up-regulation
[+]

This study demonstrates the pro-inflammatory, pro-oxidant, and genotoxic effects of microwave radiation in rat brains.Dec 01, 2015

Pubmed Data : Neurotoxicology. 2015 Dec ;51:158-65. Epub 2015 Oct 25. PMID: 26511840
Article Published Date : Dec 01, 2015
Study Type : Animal Study
Additional Links
Diseases : Brain Inflammation , DNA damage, Oxidative Stress
Anti Therapeutic Actions : Microwave Radiation
Adverse Pharmacological Actions : Glutathione Down-Regulation, Inflammatory, Interleukin-6 up-regulation, Malondialdehyde (MDA) Up-Regulation, Oxidant, Tumor necrosis factorα (TNFα) up-regulation
[+]

Expression of SDF-1/CXCR4 and related inflammatory factors in sodium fluoride-treated hepatocytes.Dec 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2024 ;19(6):e0302530. Epub 2024 Jun 21. PMID: 38905184
Article Published Date : Dec 31, 2023
Study Type : In Vitro Study
Additional Links
Diseases : Chemically-Induced Liver Damage, Fluoride Toxicity , Inflammation
Problem Substances : Sodium Fluoride
Adverse Pharmacological Actions : Interleukin-1 up-regulation, Interleukin-6 up-regulation, Tumor necrosis factorα (TNFα) up-regulation

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