Nephrotoxic

Name	AC	CK
Statin Drugs	6	35
Fenofibrates	4	25
Bisphosphonates	2	13
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)	2	13
Zoledronic Acid	2	13
Fructose	6	12
Artificial Sweeteners	1	10
Artificially Sweetened Beverages	1	10
Aspartame	1	10
Atorvastatin	1	10
Biologicals: Fetal Bovine Serum	1	10
Diclofenac	1	10
Dipyrone	1	10
Gliadin	1	10
High Fructose Corn Syrup	1	10
Ibuprofen	1	10
Naproxen	1	10
Paracetamol	1	10
Paraphenylenediamine (Hair Dye Ingredient)	1	10
Sugary soda	1	10
Lovastatin	2	6
Simvastatin	2	6
Gentamicin	2	4
Sodium Fluoride	2	4
Uranium	2	4
Dexamethasone	1	3
Mesalamine	1	3
Rosuvastatin	1	3
Varenicline (trade name Chantix)	1	3
Wheat	1	3
2,4-Dichlorophenoxyacetic acid	1	2
Airborne Pollution	1	2
Cisplatin	1	2
Cyclosporine	1	2
Cypermethrin	1	2
Glyphosate	2	2
Heavy Metals	1	2
Mercury	1	2
Sodium Chloride	1	2
Sodium hexametaphosphate	1	2
Thimerosal	1	2
Thyroxine	1	2
Tylenol	1	2
Aluminum	1	1
Bisphenol A	1	1
Fluoride	1	1
Roundup (herbicide)	1	1

Name	AC	CK
Kidney Damage: Drug-Induced	9	53
Kidney Damage	11	45
Rhabdomyolysis	7	33
Kidney Diseases	6	27
Kidney Failure: Acute	4	26
Statin-Induced Pathologies	7	24
Kidney Failure	3	21
Diabetes: Kidney Function	2	20
Children: Drug-Induced Toxicity	1	10
Creatine Phosphokinase (CK): Elevated	1	10
Death: Statin-Induced	1	10
Gluten Sensitivity	1	10
Hyperlipidemia	1	10
IgA Nephropathy	1	10
Myalgias	1	10
Occupation Related Diseases: Hair Dressers	1	10
Prostate Cancer	1	10
Proteinuria	1	10
Kidney Damage: Chemically-Induced	4	7
Oxidative Stress	4	7
Chemically-Induced Liver Damage	3	6
Nephropathy	3	6
Renal tubulointerstitial fibrosis	2	5
Chemotherapy-Induced Toxicity: Gentamicin	2	4
Fructose-Induced Toxicity	2	4
Kidney Failure: Chronic	2	4
Uranium Poisoning	2	4
Hepatitis: Acute	1	3
Hydronephrosis	1	3
Kidney Stones	1	3
Nephritis	1	3
Ulcerative Colitis	1	3
Urolithiasis	1	3
Acetaminophen (Tylenol) Toxicity	1	2
Advanced Glycation End products (AGE)	1	2
Autoimmune Diseases	1	2
Chemotherapy-Induced Toxicity: Cisplatin	1	2
Dermatitis: Contact	1	2
Hypertension: Renal	1	2
Hyperuricemia	1	2
Inflammation	1	2
Kidney Fibrosis	1	2
Metabolic Syndrome X	1	2
Myopathies	1	2
Pesticide Toxicity: Cypermethrin	1	2
Radiation Induced Illness	1	2
Alzheimer's Disease	1	1
Amyotrophic lateral sclerosis (ALS)	1	1
Chemical Exposure	1	1
Chronic Kidney Disease of Unknown Etiology (CKDu)	1	1
Liver Damage	1	1
Myositis	1	1
Parkinson's Disease	1	1

[+]

Acute renal failure has been associated with non-steroidal anti-inflammatory drugs in healthy children.Sep 01, 2005

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Pubmed Data : Pediatr Nephrol. 2005 Sep;20(9):1295-8. Epub 2005 Jun 23. PMID: 15973524

Article Published Date : Sep 01, 2005

Study Type : Human Study

Additional Links

Diseases : Children: Drug-Induced Toxicity

Problem Substances : Diclofenac, Dipyrone, Ibuprofen, Naproxen, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), Paracetamol

Adverse Pharmacological Actions : Nephrotoxic

[+]

Consumption of≥2 servings per day of artificially sweetened soda is associated with a 2-fold increased odds for kidney function decline in women.Sep 30, 2010

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Pubmed Data : Clin J Am Soc Nephrol. 2010 Sep 30. Epub 2010 Sep 30. PMID: 20884773

Article Published Date : Sep 30, 2010

Study Type : Human Study

Additional Links

Diseases : Diabetes: Kidney Function , Kidney Damage, Kidney Diseases, Kidney Failure

Problem Substances : Artificial Sweeteners, Artificially Sweetened Beverages, Aspartame

Adverse Pharmacological Actions : Nephrotoxic

[+]

Fenofibrates therapy is associated with deterioration of renal function.Jan 01, 2001

Click here to read the entire abstract

Pubmed Data : Clin Nephrol. 2001 Jan;55(1):39-44. PMID: 11200866

Article Published Date : Jan 01, 2001

Study Type : Human Study

Additional Links

Diseases : Hyperlipidemia, Kidney Damage: Drug-Induced

Problem Substances : Fenofibrates

Adverse Pharmacological Actions : Nephrotoxic

[+]

Fibrate-induced deterioration of renal function has been reported.Jan 01, 2009

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Pubmed Data : Nefrologia. 2009;29(3):208-13. PMID: 19554053

Article Published Date : Jan 01, 2009

Study Type : Human Study

Additional Links

Diseases : Kidney Damage: Drug-Induced

Problem Substances : Fenofibrates

Adverse Pharmacological Actions : Nephrotoxic

[+]

Gluten sensitivity is prevalent in patients with IgA nephropathy.Aug 01, 2009

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Pubmed Data : Nephrol Dial Transplant. 2009 Aug;24(8):2476-81. Epub 2009 Mar 30. PMID: 19332868

Article Published Date : Aug 01, 2009

Study Type : Human Study

Additional Links

Diseases : Gluten Sensitivity, IgA Nephropathy

Problem Substances : Gliadin

Adverse Pharmacological Actions : Nephrotoxic

[+]

Some patients with childhood membranous nephropathy have both circulating cationic bovine serum albumin and anti-bovine serum albumin antibodies, of which is present in vaccines.Jun 02, 2011

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Pubmed Data : N Engl J Med. 2011 Jun 2 ;364(22):2101-10. PMID: 21631322

Article Published Date : Jun 02, 2011

Study Type : Human Study

Additional Links

Anti Therapeutic Actions : Vaccination: All

Problem Substances : Biologicals: Fetal Bovine Serum

Adverse Pharmacological Actions : Nephrotoxic

[+]

Sugary soda consumption is associated with kidney damage. Jan 01, 2008

Click here to read the entire abstract

Pubmed Data : PLoS One. 2008;3(10):e3431. Epub 2008 Oct 17. PMID: 18927611

Article Published Date : Jan 01, 2008

Study Type : Human Study

Additional Links

Diseases : Diabetes: Kidney Function , Kidney Damage, Kidney Diseases, Kidney Failure

Problem Substances : High Fructose Corn Syrup, Sugary soda

Adverse Pharmacological Actions : Nephrotoxic

[+]

The FDA adverse event reporting system reveals statin-associated muscular and renal adverse events.Jan 01, 2011

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Pubmed Data : PLoS One. 2011 ;6(12):e28124. Epub 2011 Dec 20. PMID: 22205938

Article Published Date : Jan 01, 2011

Study Type : Human Study

Additional Links

Diseases : Creatine Phosphokinase (CK): Elevated, Death: Statin-Induced, Kidney Failure: Acute, Myalgias, Rhabdomyolysis

Problem Substances : Statin Drugs

Adverse Pharmacological Actions : Nephrotoxic

[+]

There is a dose-response relationship in statin-induced rhabdomyolysis.Mar 01, 2011

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Pubmed Data : Can J Cardiol. 2011 Mar-Apr;27(2):146-51. PMID: 21459261

Article Published Date : Mar 01, 2011

Study Type : Human Study

Additional Links

Diseases : Kidney Damage: Drug-Induced, Rhabdomyolysis, Statin-Induced Pathologies

Problem Substances : Atorvastatin, Statin Drugs

Adverse Pharmacological Actions : Nephrotoxic

[+]

There is an association between prolonged occupational exposure to paraphenylenediamine (hair-dye) and renal impairment.Jan 01, 2011

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Pubmed Data : Arab J Nephrol Transplant. 2011 Jan;4(1):21-5. PMID: 21469591

Article Published Date : Jan 01, 2011

Study Type : Human Study

Additional Links

Diseases : Kidney Damage, Occupation Related Diseases: Hair Dressers, Proteinuria

Problem Substances : Paraphenylenediamine (Hair Dye Ingredient)

Adverse Pharmacological Actions : Nephrotoxic

[+]

Use of high potency statins increase rates of admission for acute kidney injury.Dec 31, 2012

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Pubmed Data : BMJ. 2013 ;346:f880. Epub 2013 Mar 18. PMID: 23511950

Article Published Date : Dec 31, 2012

Study Type : Human Study

Additional Links

Diseases : Kidney Failure: Acute

Problem Substances : Statin Drugs

Adverse Pharmacological Actions : Nephrotoxic

[+]

Zolendronic acid results in renal impairment in 23,8% of the prostate cancer patients it is administered to.Mar 15, 2007

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Pubmed Data : Cancer. 2007 Mar 15;109(6):1090-6. PMID: 17311345

Article Published Date : Mar 15, 2007

Study Type : Human Study

Additional Links

Diseases : Kidney Damage: Drug-Induced, Prostate Cancer

Problem Substances : Bisphosphonates, Zoledronic Acid

Adverse Pharmacological Actions : Nephrotoxic

[+]

"A child with atypical celiac disease and recurrent urolithiasis."Mar 01, 2012

Click here to read the entire abstract

Pubmed Data : Iran J Kidney Dis. 2012 Mar ;6(2):146-8. PMID: 22388615

Article Published Date : Mar 01, 2012

Study Type : Human: Case Report

Additional Links

Diseases : Hydronephrosis, Kidney Stones, Urolithiasis

Problem Substances : Wheat

Adverse Pharmacological Actions : Nephrotoxic

[+]

A case of acute kidney injury related to intravenous zoledronic acid in a patient with multiple myeloma has been reported.Jan 01, 2009

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Pubmed Data : Nippon Jinzo Gakkai Shi. 2009;51(5):557-62. PMID: 19715164

Article Published Date : Jan 01, 2009

Study Type : Human: Case Report

Additional Links

Diseases : Kidney Damage: Drug-Induced

Additional Keywords : Drug: Doxorubicin

Problem Substances : Bisphosphonates, Dexamethasone, Zoledronic Acid

Adverse Pharmacological Actions : Nephrotoxic

[+]

Acute interstitial nephritis due to mesalazine has been reported.Apr 01, 2005

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Pubmed Data : Nephrology (Carlton). 2005 Apr;10(2):103-5. PMID: 15877665

Article Published Date : Apr 01, 2005

Study Type : Human: Case Report

Additional Links

Diseases : Nephritis, Renal tubulointerstitial fibrosis, Ulcerative Colitis

Problem Substances : Mesalamine, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

Adverse Pharmacological Actions : Nephrotoxic

[+]

Acute renal failure with the combined use of rosuvastatin and fenofibrate has been reported. Jun 01, 2010

Click here to read the entire abstract

Pubmed Data : Ren Fail. 2010 Jun;32(5):633-5. PMID: 20486848

Article Published Date : Jun 01, 2010

Study Type : Human: Case Report

Additional Links

Diseases : Kidney Failure: Acute

Problem Substances : Fenofibrates, Rosuvastatin, Statin Drugs

Adverse Pharmacological Actions : Nephrotoxic

[+]

Lovastatin monotherapy has been reported to have been a cause of rhabdomyolysis, acute renal failure and hepatopathy.Jul 01, 1997

Click here to read the entire abstract

Pubmed Data : Jpn Heart J. 1997 Jul ;38(4):541-5. PMID: 9350151

Article Published Date : Jul 01, 1997

Study Type : Human: Case Report

Additional Links

Diseases : Chemically-Induced Liver Damage, Kidney Failure: Acute, Rhabdomyolysis, Statin-Induced Pathologies

Pharmacological Actions : Anticholesteremic Agents

Problem Substances : Lovastatin

Adverse Pharmacological Actions : Nephrotoxic

[+]

Simvastatin-induced rhabdomyolysis and acute renal injury has been reported.Jan 01, 2008

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Pubmed Data : Blood Purif. 2008 ;26(4):394-8. Epub 2008 Jul 1. PMID: 18594138

Article Published Date : Jan 01, 2008

Study Type : Human: Case Report

Additional Links

Diseases : Kidney Damage: Drug-Induced, Rhabdomyolysis, Statin-Induced Pathologies

Problem Substances : Simvastatin

Adverse Pharmacological Actions : Nephrotoxic

[+]

Statin toxicity may mimic viral hepatitis. Nov 01, 2005

Click here to read the entire abstract

Pubmed Data : Int J Clin Pharmacol Ther. 2005 Nov ;43(11):543-5. PMID: 16300170

Article Published Date : Nov 01, 2005

Study Type : Human: Case Report

Additional Links

Diseases : Hepatitis: Acute, Rhabdomyolysis, Statin-Induced Pathologies

Pharmacological Actions : Anticholesteremic Agents

Problem Substances : Simvastatin

Adverse Pharmacological Actions : Myotoxicity, Nephrotoxic

[+]

Terminal renal failure in lovastatin therapy with pre-existing chronic renal insufficiency has been reported.Jan 01, 1996

Click here to read the entire abstract

Pubmed Data : Wien Klin Wochenschr. 1996 ;108(11):334-7. PMID: 8767987

Article Published Date : Jan 01, 1996

Study Type : Human: Case Report

Additional Links

Diseases : Kidney Damage: Drug-Induced, Kidney Failure: Chronic, Rhabdomyolysis, Statin-Induced Pathologies

Pharmacological Actions : Anticholesteremic Agents

Problem Substances : Lovastatin

Adverse Pharmacological Actions : Nephrotoxic

[+]

Varenicline-associated acute renal failure has been reported.Dec 01, 2008

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Pubmed Data : Ann Pharmacother. 2008 Dec;42(12):1908-11. Epub 2008 Nov 4. PMID: 18984856

Article Published Date : Dec 01, 2008

Study Type : Human: Case Report

Additional Links

Diseases : Kidney Damage, Kidney Damage: Drug-Induced

Problem Substances : Varenicline (trade name Chantix)

Adverse Pharmacological Actions : Nephrotoxic

[+]

"Pomegranate Extract Attenuates Gentamicin-Induced Nephrotoxicity in Rats by Reducing Oxidative Stress."Nov 25, 2012

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Pubmed Data : Ren Fail. 2012 Nov 26. Epub 2012 Nov 26. PMID: 23176634

Article Published Date : Nov 25, 2012

Study Type : Animal Study

Additional Links

Substances : Pomegranate

Diseases : Chemotherapy-Induced Toxicity: Gentamicin, Kidney Damage: Chemically-Induced

Pharmacological Actions : Antioxidants, Renoprotective

Additional Keywords : Drug: Gentamicin

Problem Substances : Gentamicin

Adverse Pharmacological Actions : Nephrotoxic

[+]

2,4-Dichlorophenoxyacetic acid exhibits nephrotoxic properties. Nov 01, 2011

Click here to read the entire abstract

Pubmed Data : Ecotoxicol Environ Saf. 2011 Nov ;74(8):2316-23. Epub 2011 Aug 11. PMID: 21835467

Article Published Date : Nov 01, 2011

Study Type : Animal Study

Additional Links

Diseases : Kidney Damage

Problem Substances : 2,4-Dichlorophenoxyacetic acid

Adverse Pharmacological Actions : Nephrotoxic

[+]

Acetaminophen (Tylenol) includes the toxicity associated with chronic exposure to depleted uranium. Jan 05, 2007

Click here to read the entire abstract

Pubmed Data : Toxicology. 2007 Jan 5;229(1-2):62-72. Epub 2006 Oct 17. PMID: 17126469

Article Published Date : Jan 05, 2007

Study Type : Animal Study

Additional Links

Diseases : Acetaminophen (Tylenol) Toxicity , Uranium Poisoning

Additional Keywords : Toxic Substance Synergy

Problem Substances : Tylenol, Uranium

Adverse Pharmacological Actions : Hepatotoxic, Nephrotoxic

[+]

After inhalation of particulate matter, heavy metals were absorbed via the bloodstream and selectively accumulated in target organs including blood, brain, liver and lungs in vivo. Aluminum has an affinity for the brain.Nov 19, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Sci Rep. 2015 Nov 19 ;5:16936. Epub 2015 Nov 19. PMID: 26582271

Article Published Date : Nov 19, 2015

Study Type : Animal Study

Additional Links

Problem Substances : Airborne Pollution, Heavy Metals

Adverse Pharmacological Actions : Hepatotoxic, Nephrotoxic, Neurotoxic

[+]

Berberine protects against fructose-and-salt induced hypertensive renal injury. Mar 01, 2011

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Pubmed Data : Zhong Yao Cai. 2011 Mar ;34(3):412-5. PMID: 21823461

Article Published Date : Mar 01, 2011

Study Type : Animal Study

Additional Links

Substances : Berberine

Diseases : Fructose-Induced Toxicity , Hypertension: Renal, Kidney Diseases

Pharmacological Actions : Renoprotective

Problem Substances : Fructose, Sodium Chloride

Adverse Pharmacological Actions : Nephrotoxic

[+]

Dietary fructose causes tubulointerstitial injury in the normal rat kidney.Mar 01, 2010

Click here to read the entire abstract

Pubmed Data : Am J Physiol Renal Physiol. 2010 Mar;298(3):F712-20. Epub 2010 Jan 13. PMID: 20071464

Article Published Date : Mar 01, 2010

Study Type : Animal Study

Additional Links

Diseases : Renal tubulointerstitial fibrosis

Problem Substances : Fructose

Adverse Pharmacological Actions : Nephrotoxic

[+]

Exposure to static magnetic fields induced oxidative stress in rat kidneys that can be prevented by treatment with selenium or vitamin E.Jan 01, 2015

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Pubmed Data : Gen Physiol Biophys. 2015 Jan ;34(1):23-32. Epub 2014 Nov 14. PMID: 25395602

Article Published Date : Jan 01, 2015

Study Type : Animal Study

Additional Links

Substances : Selenium, Vitamin E

Diseases : Oxidative Stress

Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation

Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation

Adverse Pharmacological Actions : Malondialdehyde (MDA) Up-Regulation, Nephrotoxic, Oxidant

[+]

Fenofibrate induce muscular toxicity in rats.Jan 01, 2009

Click here to read the entire abstract

Pubmed Data : Toxicol Pathol. 2009;37(4):517-20. Epub 2009 Apr 24. PMID: 19395589

Article Published Date : Jan 01, 2009

Study Type : Animal Study

Additional Links

Diseases : Myopathies

Problem Substances : Fenofibrates

Adverse Pharmacological Actions : Nephrotoxic

[+]

Fructose causes renal damage in an animal model of metabolic syndrome. May 01, 2011

Click here to read the entire abstract

Pubmed Data : Pediatr Nephrol. 2011 May 1. Epub 2011 May 1. PMID: 21533627

Article Published Date : May 01, 2011

Study Type : Animal Study

Additional Links

Diseases : Fructose-Induced Toxicity , Kidney Damage, Metabolic Syndrome X

Problem Substances : Fructose

Adverse Pharmacological Actions : Inflammatory, Nephrotoxic

[+]

Fructose induces nephropathy and hyperuricemia in rats. May 25, 2011

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Pubmed Data : Planta Med. 2011 May 25. Epub 2011 May 25. PMID: 21614752

Article Published Date : May 25, 2011

Study Type : Animal Study

Additional Links

Diseases : Hyperuricemia, Nephropathy

Problem Substances : Fructose

Adverse Pharmacological Actions : Interleukin-1 up-regulation, Nephrotoxic, Prostaglandin E2 up-regulation

[+]

Fructose, but not dextrose, accelerates the progression of chronic kidney disease.Oct 01, 2007

Click here to read the entire abstract

Pubmed Data : Am J Physiol Renal Physiol. 2007 Oct;293(4):F1256-61. Epub 2007 Aug 1. PMID: 17670904

Article Published Date : Oct 01, 2007

Study Type : Animal Study

Additional Links

Diseases : Kidney Diseases

Problem Substances : Fructose

Adverse Pharmacological Actions : Nephrotoxic

[+]

Fructose-fed rats exhibit increased inflammation, fibrogenesis and NF-κB activation.Jun 17, 2011

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Pubmed Data : Eur J Pharmacol. 2011 Jun 17. Epub 2011 Jun 17. PMID: 21704028

Article Published Date : Jun 17, 2011

Study Type : Animal Study

Additional Links

Diseases : Advanced Glycation End products (AGE), Inflammation, Kidney Damage, Kidney Diseases, Kidney Fibrosis

Problem Substances : Fructose

Adverse Pharmacological Actions : Inflammatory, Nephrotoxic, NF-kappaB up-regulation, Oxidant, Profibrotic

[+]

L-thyroxine increases oxidative stress in rat renal cortex.Feb 01, 2011

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Pubmed Data : Mol Biol Rep. 2011 Feb;38(2):1047-54. Epub 2010 Jun 24. PMID: 20574713

Article Published Date : Feb 01, 2011

Study Type : Animal Study

Additional Links

Problem Substances : Thyroxine

Adverse Pharmacological Actions : Nephrotoxic

[+]

Melatonin and caffeic acid phenethyl ester prevent renal tubular injury by reducing oxidative stress and protect the kidney from oxidative damage induced by 900 MHz mobile phone.Aug 01, 2005

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Pubmed Data : Mol Cell Biochem. 2005 Aug ;276(1-2):31-7. PMID: 16132682

Article Published Date : Aug 01, 2005

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester, Melatonin

Diseases : Radiation Induced Illness

Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation

Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation

Adverse Pharmacological Actions : Nephrotoxic

[+]

Mice administered thimerosal develop an age-dependent spontaneous systemic autoimmune disease with high mortality primarily due to immune-complex glomerulonephritis.Jul 01, 2006

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Pubmed Data : Toxicol Appl Pharmacol. 2006 Jul 1 ;214(1):43-54. Epub 2006 Jan 27. PMID: 16443248

Article Published Date : Jul 01, 2006

Study Type : Animal Study

Additional Links

Diseases : Autoimmune Diseases

Additional Keywords : Autoimmunity, Vaccine Research

Problem Substances : Mercury, Thimerosal

Adverse Pharmacological Actions : Immunoreactive, Nephrotoxic

[+]

Olive leaf extract ameliorates gentamicin nephrotoxicity via antioxidant activity, increase of renal glutathione content, and increase of renal antioxidant enzymes activity, except for glutathione peroxidase.Jan 01, 2012

Click here to read the entire abstract

Pubmed Data : Iran J Kidney Dis. 2012 Jan ;6(1):25-32. PMID: 22218116

Article Published Date : Jan 01, 2012

Study Type : Animal Study

Additional Links

Substances : Olive leaf extract

Diseases : Chemotherapy-Induced Toxicity: Gentamicin

Pharmacological Actions : Antioxidants, Glutathione Upregulation , Renoprotective

Problem Substances : Gentamicin

Adverse Pharmacological Actions : Nephrotoxic, Oxidant

[+]

Sesame oil protects against cypermethrin-induced toxicity to rat liver and kidney.Jan 01, 2012

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Pubmed Data : J Environ Sci Health B. 2012 ;47(4):306-14. PMID: 22428892

Article Published Date : Jan 01, 2012

Study Type : Animal Study

Additional Links

Substances : Sesame Seed Oil

Diseases : Chemically-Induced Liver Damage, Kidney Damage: Chemically-Induced, Pesticide Toxicity: Cypermethrin

Problem Substances : Cypermethrin

Adverse Pharmacological Actions : Hepatotoxic, Nephrotoxic

[+]

Sodium fluoride administered through drinking water exhibits liver and kidney toxicity in mice. Sep 22, 2010

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Pubmed Data : Arch Toxicol. 2010 Sep 22. Epub 2010 Sep 22. PMID: 20859737

Article Published Date : Sep 22, 2010

Study Type : Animal Study

Additional Links

Problem Substances : Sodium Fluoride

Adverse Pharmacological Actions : Hepatotoxic, Nephrotoxic

[+]

Sodium fluoride has adverse effects in the fetal kidney during pregnancy.Aug 31, 2024

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Environ Toxicol Pharmacol. 2024 Sep ;110:104545. Epub 2024 Aug 28. PMID: 39208996

Article Published Date : Aug 31, 2024

Study Type : Animal Study

Additional Links

Diseases : Kidney Damage: Chemically-Induced

Problem Substances : Sodium Fluoride

Adverse Pharmacological Actions : Nephrotoxic

[+]

Sodium hexametaphosphate is a skin irritant topically and has adverse kidney effects when ingested (10% diet) animal experiments..Jan 01, 2001

Click here to read the entire abstract

Pubmed Data : Int J Toxicol. 2001;20 Suppl 3:75-89. PMID: 11766135

Article Published Date : Jan 01, 2001

Study Type : Animal Study

Additional Links

Diseases : Dermatitis: Contact, Kidney Damage

Problem Substances : Sodium hexametaphosphate

Adverse Pharmacological Actions : Nephrotoxic

[+]

Spirulina platensis is a potent antioxidant that could ameliorate the effect of chromium induced nephrotoxicity and provided a near complete protection.Dec 31, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2015 ;10(6):e0126780. Epub 2015 Jun 1. PMID: 26029926

Article Published Date : Dec 31, 2014

Study Type : Animal Study

Additional Links

Substances : Spirulina

Diseases : Oxidative Stress

Pharmacological Actions : Antioxidants, Renoprotective

Additional Keywords : Risk Reduction

Adverse Pharmacological Actions : Nephrotoxic

[+]

Sulforaphane prevents cell death and inflammation in nephropathy.Jun 16, 2011

Click here to read the entire abstract

Pubmed Data : J Nutr Biochem. 2011 Jun 16. Epub 2011 Jun 16. PMID: 21684138

Article Published Date : Jun 16, 2011

Study Type : Animal Study

Additional Links

Substances : Sulforaphane

Diseases : Chemotherapy-Induced Toxicity: Cisplatin, Nephropathy

Pharmacological Actions : Renoprotective

Problem Substances : Cisplatin

Adverse Pharmacological Actions : Nephrotoxic

[+]

The reduced form of coenzyme Q10 may prevent or minimize cyclosporine nephrotoxicity by an antioxidant effect.Nov 27, 2012

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Pubmed Data : Exp Clin Transplant. 2012 Nov 28. Epub 2012 Nov 28. PMID: 23194328

Article Published Date : Nov 27, 2012

Study Type : Animal Study

Additional Links

Substances : Ubiquinol

Diseases : Nephropathy

Pharmacological Actions : Renoprotective

Problem Substances : Cyclosporine

Adverse Pharmacological Actions : Nephrotoxic

[+]

These findings suggest that GSM-like radiofrequency radiation interferes with gene expression during early gestation and results in aberrations of bone morphogenetic protein expression in the newborn.Apr 01, 2004

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Pubmed Data : Bioelectromagnetics. 2004 Apr ;25(3):216-27. PMID: 15042631

Article Published Date : Apr 01, 2004

Study Type : Animal Study

Additional Links

Additional Keywords : Pregnancy, Pregnancy And Fetal Growth

Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation

Adverse Pharmacological Actions : Nephrotoxic

[+]

Uranium nitrate is renotoxic and dramatically alters the expression of more than 200 genes in the rat kidney. Nov 01, 2004

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Pubmed Data : Environ Health Perspect. 2004 Nov;112(16):1628-35. PMID: 15598614

Article Published Date : Nov 01, 2004

Study Type : Animal Study

Additional Links

Diseases : Kidney Damage, Oxidative Stress, Uranium Poisoning

Problem Substances : Uranium

Adverse Pharmacological Actions : Genotoxic, Nephrotoxic

[+]

Aluminum is implicated in Alzheimer's, ALS, and parkinsonism-dementia. Its accumulation occurs primarily in infants and children with immature or impaired renal function.Jun 01, 1990

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Pubmed Data : Clin Lab Med. 1990 Jun ;10(2):403-22. PMID: 2197055

Article Published Date : Jun 01, 1990

Study Type : Review

Additional Links

Diseases : Alzheimer's Disease, Amyotrophic lateral sclerosis (ALS), Kidney Failure: Chronic, Parkinson's Disease

Anti Therapeutic Actions : Vaccination: All

Problem Substances : Aluminum

Adverse Pharmacological Actions : Bioaccumulator, Nephrotoxic, Neurotoxic

[+]

Clear toxicities of pollutants were observed cell lines at very low sub-agricultural dilutions.Jan 01, 2011

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Pubmed Data : J Occup Med Toxicol. 2011;6(1):3. Epub 2011 Jan 20. PMID: 21251308

Article Published Date : Jan 01, 2011

Study Type : In Vitro Study

Additional Links

Diseases : Chemical Exposure, Chemically-Induced Liver Damage, Kidney Damage, Liver Damage

Problem Substances : Bisphenol A , Glyphosate

Adverse Pharmacological Actions : Hepatotoxic, Nephrotoxic

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Glyphosate, hard water and nephrotoxic metals: are they the culprits behind the epidemic of chronic kidney disease of unknown etiology in sri lanka?Dec 31, 2013

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Pubmed Data : Int J Environ Res Public Health. 2014 ;11(2):2125-47. Epub 2014 Feb 20. PMID: 24562182

Article Published Date : Dec 31, 2013

Study Type : Review

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Diseases : Chronic Kidney Disease of Unknown Etiology (CKDu), Kidney Damage: Chemically-Induced, Kidney Diseases

Problem Substances : Glyphosate, Roundup (herbicide)

Adverse Pharmacological Actions : Nephrotoxic

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High fluoride aggravates cadmium-mediated nephrotoxicity of renal tubular epithelial cells.Nov 24, 2024

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Pubmed Data : Sci Total Environ. 2024 Nov 25 ;953:175927. Epub 2024 Sep 3. PMID: 39236818

Article Published Date : Nov 24, 2024

Study Type : In Vitro Study

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Diseases : Oxidative Stress

Pharmacological Actions : Apoptotic

Problem Substances : Fluoride

Adverse Pharmacological Actions : Nephrotoxic

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Statin drugs have been linked to rhabdomyolysis, myositis and kidney failure. Oct 21, 2011

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Pubmed Data : Curr Vasc Pharmacol. 2011 Oct 21. Epub 2011 Oct 21. PMID: 22022768

Article Published Date : Oct 21, 2011

Study Type : Review

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Diseases : Kidney Damage: Drug-Induced, Kidney Failure, Myositis, Rhabdomyolysis, Statin-Induced Pathologies

Problem Substances : Statin Drugs

Adverse Pharmacological Actions : Myotoxicity, Nephrotoxic

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Statin drugs induce cell death in mouse kidney cells.Oct 01, 1997

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Pubmed Data : Kidney Int. 1997 Oct ;52(4):962-72. PMID: 9328935

Article Published Date : Oct 01, 1997

Study Type : In Vitro Study

Additional Links

Diseases : Kidney Damage, Statin-Induced Pathologies

Problem Substances : Statin Drugs

Adverse Pharmacological Actions : Apoptotic, Cytotoxic, Nephrotoxic

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View the Evidence: 52 Abstracts with Nephrotoxic Research

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Acute renal failure has been associated with non-steroidal anti-inflammatory drugs in healthy children.Sep 01, 2005

Consumption of≥2 servings per day of artificially sweetened soda is associated with a 2-fold increased odds for kidney function decline in women.Sep 30, 2010

Fenofibrates therapy is associated with deterioration of renal function.Jan 01, 2001

Fibrate-induced deterioration of renal function has been reported.Jan 01, 2009

Gluten sensitivity is prevalent in patients with IgA nephropathy.Aug 01, 2009

Some patients with childhood membranous nephropathy have both circulating cationic bovine serum albumin and anti-bovine serum albumin antibodies, of which is present in vaccines.Jun 02, 2011

Sugary soda consumption is associated with kidney damage. Jan 01, 2008

The FDA adverse event reporting system reveals statin-associated muscular and renal adverse events.Jan 01, 2011

There is a dose-response relationship in statin-induced rhabdomyolysis.Mar 01, 2011

There is an association between prolonged occupational exposure to paraphenylenediamine (hair-dye) and renal impairment.Jan 01, 2011

Use of high potency statins increase rates of admission for acute kidney injury.Dec 31, 2012

Zolendronic acid results in renal impairment in 23,8% of the prostate cancer patients it is administered to.Mar 15, 2007

"A child with atypical celiac disease and recurrent urolithiasis."Mar 01, 2012

A case of acute kidney injury related to intravenous zoledronic acid in a patient with multiple myeloma has been reported.Jan 01, 2009

Acute interstitial nephritis due to mesalazine has been reported.Apr 01, 2005

Acute renal failure with the combined use of rosuvastatin and fenofibrate has been reported. Jun 01, 2010

Lovastatin monotherapy has been reported to have been a cause of rhabdomyolysis, acute renal failure and hepatopathy.Jul 01, 1997

Simvastatin-induced rhabdomyolysis and acute renal injury has been reported.Jan 01, 2008

Statin toxicity may mimic viral hepatitis. Nov 01, 2005

Terminal renal failure in lovastatin therapy with pre-existing chronic renal insufficiency has been reported.Jan 01, 1996

Varenicline-associated acute renal failure has been reported.Dec 01, 2008

"Pomegranate Extract Attenuates Gentamicin-Induced Nephrotoxicity in Rats by Reducing Oxidative Stress."Nov 25, 2012

2,4-Dichlorophenoxyacetic acid exhibits nephrotoxic properties. Nov 01, 2011

Acetaminophen (Tylenol) includes the toxicity associated with chronic exposure to depleted uranium. Jan 05, 2007

After inhalation of particulate matter, heavy metals were absorbed via the bloodstream and selectively accumulated in target organs including blood, brain, liver and lungs in vivo. Aluminum has an affinity for the brain.Nov 19, 2015

Berberine protects against fructose-and-salt induced hypertensive renal injury. Mar 01, 2011

Dietary fructose causes tubulointerstitial injury in the normal rat kidney.Mar 01, 2010

Exposure to static magnetic fields induced oxidative stress in rat kidneys that can be prevented by treatment with selenium or vitamin E.Jan 01, 2015

Fenofibrate induce muscular toxicity in rats.Jan 01, 2009

Fructose causes renal damage in an animal model of metabolic syndrome. May 01, 2011

Fructose induces nephropathy and hyperuricemia in rats. May 25, 2011

Fructose, but not dextrose, accelerates the progression of chronic kidney disease.Oct 01, 2007

Fructose-fed rats exhibit increased inflammation, fibrogenesis and NF-κB activation.Jun 17, 2011

L-thyroxine increases oxidative stress in rat renal cortex.Feb 01, 2011

Melatonin and caffeic acid phenethyl ester prevent renal tubular injury by reducing oxidative stress and protect the kidney from oxidative damage induced by 900 MHz mobile phone.Aug 01, 2005

Mice administered thimerosal develop an age-dependent spontaneous systemic autoimmune disease with high mortality primarily due to immune-complex glomerulonephritis.Jul 01, 2006

Olive leaf extract ameliorates gentamicin nephrotoxicity via antioxidant activity, increase of renal glutathione content, and increase of renal antioxidant enzymes activity, except for glutathione peroxidase.Jan 01, 2012

Sesame oil protects against cypermethrin-induced toxicity to rat liver and kidney.Jan 01, 2012

Sodium fluoride administered through drinking water exhibits liver and kidney toxicity in mice. Sep 22, 2010

Sodium fluoride has adverse effects in the fetal kidney during pregnancy.Aug 31, 2024

Sodium hexametaphosphate is a skin irritant topically and has adverse kidney effects when ingested (10% diet) animal experiments..Jan 01, 2001

Spirulina platensis is a potent antioxidant that could ameliorate the effect of chromium induced nephrotoxicity and provided a near complete protection.Dec 31, 2014

Sulforaphane prevents cell death and inflammation in nephropathy.Jun 16, 2011

The reduced form of coenzyme Q10 may prevent or minimize cyclosporine nephrotoxicity by an antioxidant effect.Nov 27, 2012

These findings suggest that GSM-like radiofrequency radiation interferes with gene expression during early gestation and results in aberrations of bone morphogenetic protein expression in the newborn.Apr 01, 2004

Uranium nitrate is renotoxic and dramatically alters the expression of more than 200 genes in the rat kidney. Nov 01, 2004

Aluminum is implicated in Alzheimer's, ALS, and parkinsonism-dementia. Its accumulation occurs primarily in infants and children with immature or impaired renal function.Jun 01, 1990

Clear toxicities of pollutants were observed cell lines at very low sub-agricultural dilutions.Jan 01, 2011

Glyphosate, hard water and nephrotoxic metals: are they the culprits behind the epidemic of chronic kidney disease of unknown etiology in sri lanka?Dec 31, 2013

High fluoride aggravates cadmium-mediated nephrotoxicity of renal tubular epithelial cells.Nov 24, 2024

Statin drugs have been linked to rhabdomyolysis, myositis and kidney failure. Oct 21, 2011

Statin drugs induce cell death in mouse kidney cells.Oct 01, 1997

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View the Evidence:
52 Abstracts with Nephrotoxic Research