Nephrotoxic

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46 Problem Substances Researched for Nephrotoxic
NameACCKFocus
Statin Drugs635Locked
Fenofibrates425Locked
Bisphosphonates213Locked
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)213Locked
Zoledronic Acid213Locked
Fructose612Locked
Artificial Sweeteners110Locked
Artificially Sweetened Beverages110Locked
Aspartame110Locked
Atorvastatin110Locked
Biologicals: Fetal Bovine Serum110Locked
Diclofenac110Locked
Dipyrone110Locked
Gliadin110Locked
High Fructose Corn Syrup110Locked
Ibuprofen110Locked
Naproxen110Locked
Paracetamol110Locked
Paraphenylenediamine (Hair Dye Ingredient)110Locked
Sugary soda110Locked
Lovastatin26Locked
Simvastatin26Locked
Gentamicin24Locked
Uranium24Locked
Dexamethasone13Locked
Mesalamine13Locked
Rosuvastatin13Locked
Varenicline (trade name Chantix)13Locked
Wheat13Locked
2,4-Dichlorophenoxyacetic acid12Locked
Airborne Pollution12Locked
Cisplatin12Locked
Cyclosporine12Locked
Cypermethrin12Locked
Glyphosate22Locked
Heavy Metals12Locked
Mercury12Locked
Sodium Chloride12Locked
Sodium Fluoride12Locked
Sodium hexametaphosphate12Locked
Thimerosal 12Locked
Thyroxine12Locked
Tylenol12Locked
Aluminum11Locked
Bisphenol A 11Locked
Roundup (herbicide)11Locked
53 Diseases Researched for Nephrotoxic
NameACCKFocus
Kidney Damage: Drug-Induced953Locked
Kidney Damage1145Locked
Rhabdomyolysis733Locked
Kidney Diseases627Locked
Kidney Failure: Acute426Locked
Statin-Induced Pathologies724Locked
Kidney Failure321Locked
Diabetes: Kidney Function 220Locked
Children: Drug-Induced Toxicity110Locked
Creatine Phosphokinase (CK): Elevated110Locked
Death: Statin-Induced110Locked
Gluten Sensitivity110Locked
Hyperlipidemia110Locked
IgA Nephropathy110Locked
Myalgias110Locked
Occupation Related Diseases: Hair Dressers110Locked
Prostate Cancer110Locked
Proteinuria110Locked
Chemically-Induced Liver Damage36Locked
Nephropathy36Locked
Oxidative Stress36Locked
Kidney Damage: Chemically-Induced35Locked
Renal tubulointerstitial fibrosis25Locked
Chemotherapy-Induced Toxicity: Gentamicin24Locked
Fructose-Induced Toxicity 24Locked
Kidney Failure: Chronic24Locked
Uranium Poisoning24Locked
Hepatitis: Acute13Locked
Hydronephrosis13Locked
Kidney Stones13Locked
Nephritis13Locked
Ulcerative Colitis13Locked
Urolithiasis13Locked
Acetaminophen (Tylenol) Toxicity 12Locked
Advanced Glycation End products (AGE)12Locked
Autoimmune Diseases12Locked
Chemotherapy-Induced Toxicity: Cisplatin12Locked
Dermatitis: Contact12Locked
Hypertension: Renal12Locked
Hyperuricemia12Locked
Inflammation12Locked
Kidney Fibrosis12Locked
Metabolic Syndrome X12Locked
Myopathies12Locked
Pesticide Toxicity: Cypermethrin12Locked
Radiation Induced Illness12Locked
Alzheimer's Disease11Locked
Amyotrophic lateral sclerosis (ALS)11Locked
Chemical Exposure11Locked
Chronic Kidney Disease of Unknown Etiology (CKDu)11Locked
Liver Damage11Locked
Myositis11Locked
Parkinson's Disease11Locked

View the Evidence:
50 Abstracts with Nephrotoxic Research

[+]

Acute renal failure has been associated with non-steroidal anti-inflammatory drugs in healthy children.Sep 01, 2005

Pubmed Data : Pediatr Nephrol. 2005 Sep;20(9):1295-8. Epub 2005 Jun 23. PMID: 15973524
Article Published Date : Sep 01, 2005
Study Type : Human Study
Additional Links
Diseases : Children: Drug-Induced Toxicity
Problem Substances : Diclofenac, Dipyrone, Ibuprofen, Naproxen, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), Paracetamol
Adverse Pharmacological Actions : Nephrotoxic
[+]

Consumption of≥2 servings per day of artificially sweetened soda is associated with a 2-fold increased odds for kidney function decline in women.Sep 30, 2010

Pubmed Data : Clin J Am Soc Nephrol. 2010 Sep 30. Epub 2010 Sep 30. PMID: 20884773
Article Published Date : Sep 30, 2010
Study Type : Human Study
Additional Links
Diseases : Diabetes: Kidney Function , Kidney Damage, Kidney Diseases, Kidney Failure
Problem Substances : Artificial Sweeteners, Artificially Sweetened Beverages, Aspartame
Adverse Pharmacological Actions : Nephrotoxic
[+]

Fenofibrates therapy is associated with deterioration of renal function.Jan 01, 2001

Pubmed Data : Clin Nephrol. 2001 Jan;55(1):39-44. PMID: 11200866
Article Published Date : Jan 01, 2001
Study Type : Human Study
Additional Links
Diseases : Hyperlipidemia, Kidney Damage: Drug-Induced
Problem Substances : Fenofibrates
Adverse Pharmacological Actions : Nephrotoxic
[+]

Fibrate-induced deterioration of renal function has been reported.Jan 01, 2009

Pubmed Data : Nefrologia. 2009;29(3):208-13. PMID: 19554053
Article Published Date : Jan 01, 2009
Study Type : Human Study
Additional Links
Diseases : Kidney Damage: Drug-Induced
Problem Substances : Fenofibrates
Adverse Pharmacological Actions : Nephrotoxic
[+]

Gluten sensitivity is prevalent in patients with IgA nephropathy.Aug 01, 2009

Pubmed Data : Nephrol Dial Transplant. 2009 Aug;24(8):2476-81. Epub 2009 Mar 30. PMID: 19332868
Article Published Date : Aug 01, 2009
Study Type : Human Study
Additional Links
Diseases : Gluten Sensitivity, IgA Nephropathy
Problem Substances : Gliadin
Adverse Pharmacological Actions : Nephrotoxic
[+]

Some patients with childhood membranous nephropathy have both circulating cationic bovine serum albumin and anti-bovine serum albumin antibodies, of which is present in vaccines.Jun 02, 2011

Pubmed Data : N Engl J Med. 2011 Jun 2 ;364(22):2101-10. PMID: 21631322
Article Published Date : Jun 02, 2011
Study Type : Human Study
Additional Links
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Biologicals: Fetal Bovine Serum
Adverse Pharmacological Actions : Nephrotoxic
[+]

Sugary soda consumption is associated with kidney damage. Jan 01, 2008

Pubmed Data : PLoS One. 2008;3(10):e3431. Epub 2008 Oct 17. PMID: 18927611
Article Published Date : Jan 01, 2008
Study Type : Human Study
Additional Links
Diseases : Diabetes: Kidney Function , Kidney Damage, Kidney Diseases, Kidney Failure
Problem Substances : High Fructose Corn Syrup, Sugary soda
Adverse Pharmacological Actions : Nephrotoxic
[+]

The FDA adverse event reporting system reveals statin-associated muscular and renal adverse events.Jan 01, 2011

Pubmed Data : PLoS One. 2011 ;6(12):e28124. Epub 2011 Dec 20. PMID: 22205938
Article Published Date : Jan 01, 2011
Study Type : Human Study
Additional Links
Diseases : Creatine Phosphokinase (CK): Elevated, Death: Statin-Induced, Kidney Failure: Acute, Myalgias, Rhabdomyolysis
Problem Substances : Statin Drugs
Adverse Pharmacological Actions : Nephrotoxic
[+]

There is a dose-response relationship in statin-induced rhabdomyolysis.Mar 01, 2011

Pubmed Data : Can J Cardiol. 2011 Mar-Apr;27(2):146-51. PMID: 21459261
Article Published Date : Mar 01, 2011
Study Type : Human Study
Additional Links
Diseases : Kidney Damage: Drug-Induced, Rhabdomyolysis, Statin-Induced Pathologies
Problem Substances : Atorvastatin, Statin Drugs
Adverse Pharmacological Actions : Nephrotoxic
[+]

There is an association between prolonged occupational exposure to paraphenylenediamine (hair-dye) and renal impairment.Jan 01, 2011

Pubmed Data : Arab J Nephrol Transplant. 2011 Jan;4(1):21-5. PMID: 21469591
Article Published Date : Jan 01, 2011
Study Type : Human Study
Additional Links
Diseases : Kidney Damage, Occupation Related Diseases: Hair Dressers, Proteinuria
Problem Substances : Paraphenylenediamine (Hair Dye Ingredient)
Adverse Pharmacological Actions : Nephrotoxic
[+]

Use of high potency statins increase rates of admission for acute kidney injury.Dec 31, 2012

Pubmed Data : BMJ. 2013 ;346:f880. Epub 2013 Mar 18. PMID: 23511950
Article Published Date : Dec 31, 2012
Study Type : Human Study
Additional Links
Diseases : Kidney Failure: Acute
Problem Substances : Statin Drugs
Adverse Pharmacological Actions : Nephrotoxic
[+]

Zolendronic acid results in renal impairment in 23,8% of the prostate cancer patients it is administered to.Mar 15, 2007

Pubmed Data : Cancer. 2007 Mar 15;109(6):1090-6. PMID: 17311345
Article Published Date : Mar 15, 2007
Study Type : Human Study
Additional Links
Diseases : Kidney Damage: Drug-Induced, Prostate Cancer
Problem Substances : Bisphosphonates, Zoledronic Acid
Adverse Pharmacological Actions : Nephrotoxic
[+]

"A child with atypical celiac disease and recurrent urolithiasis."Mar 01, 2012

Pubmed Data : Iran J Kidney Dis. 2012 Mar ;6(2):146-8. PMID: 22388615
Article Published Date : Mar 01, 2012
Study Type : Human: Case Report
Additional Links
Diseases : Hydronephrosis, Kidney Stones, Urolithiasis
Problem Substances : Wheat
Adverse Pharmacological Actions : Nephrotoxic
[+]

A case of acute kidney injury related to intravenous zoledronic acid in a patient with multiple myeloma has been reported.Jan 01, 2009

Pubmed Data : Nippon Jinzo Gakkai Shi. 2009;51(5):557-62. PMID: 19715164
Article Published Date : Jan 01, 2009
Study Type : Human: Case Report
Additional Links
Diseases : Kidney Damage: Drug-Induced
Additional Keywords : Drug: Doxorubicin
Problem Substances : Bisphosphonates, Dexamethasone, Zoledronic Acid
Adverse Pharmacological Actions : Nephrotoxic
[+]

Acute interstitial nephritis due to mesalazine has been reported.Apr 01, 2005

Pubmed Data : Nephrology (Carlton). 2005 Apr;10(2):103-5. PMID: 15877665
Article Published Date : Apr 01, 2005
Study Type : Human: Case Report
Additional Links
Diseases : Nephritis, Renal tubulointerstitial fibrosis, Ulcerative Colitis
Problem Substances : Mesalamine, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
Adverse Pharmacological Actions : Nephrotoxic
[+]

Acute renal failure with the combined use of rosuvastatin and fenofibrate has been reported. Jun 01, 2010

Pubmed Data : Ren Fail. 2010 Jun;32(5):633-5. PMID: 20486848
Article Published Date : Jun 01, 2010
Study Type : Human: Case Report
Additional Links
Diseases : Kidney Failure: Acute
Problem Substances : Fenofibrates, Rosuvastatin, Statin Drugs
Adverse Pharmacological Actions : Nephrotoxic
[+]

Lovastatin monotherapy has been reported to have been a cause of rhabdomyolysis, acute renal failure and hepatopathy.Jul 01, 1997

Pubmed Data : Jpn Heart J. 1997 Jul ;38(4):541-5. PMID: 9350151
Article Published Date : Jul 01, 1997
Study Type : Human: Case Report
Additional Links
Diseases : Chemically-Induced Liver Damage, Kidney Failure: Acute, Rhabdomyolysis, Statin-Induced Pathologies
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Lovastatin
Adverse Pharmacological Actions : Nephrotoxic
[+]

Simvastatin-induced rhabdomyolysis and acute renal injury has been reported.Jan 01, 2008

Pubmed Data : Blood Purif. 2008 ;26(4):394-8. Epub 2008 Jul 1. PMID: 18594138
Article Published Date : Jan 01, 2008
Study Type : Human: Case Report
Additional Links
Diseases : Kidney Damage: Drug-Induced, Rhabdomyolysis, Statin-Induced Pathologies
Problem Substances : Simvastatin
Adverse Pharmacological Actions : Nephrotoxic
[+]

Statin toxicity may mimic viral hepatitis. Nov 01, 2005

Pubmed Data : Int J Clin Pharmacol Ther. 2005 Nov ;43(11):543-5. PMID: 16300170
Article Published Date : Nov 01, 2005
Study Type : Human: Case Report
Additional Links
Diseases : Hepatitis: Acute, Rhabdomyolysis, Statin-Induced Pathologies
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Simvastatin
Adverse Pharmacological Actions : Myotoxicity, Nephrotoxic
[+]

Terminal renal failure in lovastatin therapy with pre-existing chronic renal insufficiency has been reported.Jan 01, 1996

Pubmed Data : Wien Klin Wochenschr. 1996 ;108(11):334-7. PMID: 8767987
Article Published Date : Jan 01, 1996
Study Type : Human: Case Report
Additional Links
Diseases : Kidney Damage: Drug-Induced, Kidney Failure: Chronic, Rhabdomyolysis, Statin-Induced Pathologies
Pharmacological Actions : Anticholesteremic Agents
Problem Substances : Lovastatin
Adverse Pharmacological Actions : Nephrotoxic
[+]

Varenicline-associated acute renal failure has been reported.Dec 01, 2008

Pubmed Data : Ann Pharmacother. 2008 Dec;42(12):1908-11. Epub 2008 Nov 4. PMID: 18984856
Article Published Date : Dec 01, 2008
Study Type : Human: Case Report
Additional Links
Diseases : Kidney Damage, Kidney Damage: Drug-Induced
Problem Substances : Varenicline (trade name Chantix)
Adverse Pharmacological Actions : Nephrotoxic
[+]

"Pomegranate Extract Attenuates Gentamicin-Induced Nephrotoxicity in Rats by Reducing Oxidative Stress."Nov 25, 2012

Pubmed Data : Ren Fail. 2012 Nov 26. Epub 2012 Nov 26. PMID: 23176634
Article Published Date : Nov 25, 2012
Study Type : Animal Study
Additional Links
Substances : Pomegranate
Diseases : Chemotherapy-Induced Toxicity: Gentamicin, Kidney Damage: Chemically-Induced
Pharmacological Actions : Antioxidants, Renoprotective
Additional Keywords : Drug: Gentamicin
Problem Substances : Gentamicin
Adverse Pharmacological Actions : Nephrotoxic
[+]

2,4-Dichlorophenoxyacetic acid exhibits nephrotoxic properties. Nov 01, 2011

Pubmed Data : Ecotoxicol Environ Saf. 2011 Nov ;74(8):2316-23. Epub 2011 Aug 11. PMID: 21835467
Article Published Date : Nov 01, 2011
Study Type : Animal Study
Additional Links
Diseases : Kidney Damage
Problem Substances : 2,4-Dichlorophenoxyacetic acid
Adverse Pharmacological Actions : Nephrotoxic
[+]

Acetaminophen (Tylenol) includes the toxicity associated with chronic exposure to depleted uranium. Jan 05, 2007

Pubmed Data : Toxicology. 2007 Jan 5;229(1-2):62-72. Epub 2006 Oct 17. PMID: 17126469
Article Published Date : Jan 05, 2007
Study Type : Animal Study
Additional Links
Diseases : Acetaminophen (Tylenol) Toxicity , Uranium Poisoning
Additional Keywords : Toxic Substance Synergy
Problem Substances : Tylenol, Uranium
Adverse Pharmacological Actions : Hepatotoxic, Nephrotoxic
[+]

After inhalation of particulate matter, heavy metals were absorbed via the bloodstream and selectively accumulated in target organs including blood, brain, liver and lungs in vivo. Aluminum has an affinity for the brain.Nov 19, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2015 Nov 19 ;5:16936. Epub 2015 Nov 19. PMID: 26582271
Article Published Date : Nov 19, 2015
Study Type : Animal Study
Additional Links
Problem Substances : Airborne Pollution, Heavy Metals
Adverse Pharmacological Actions : Hepatotoxic, Nephrotoxic, Neurotoxic
[+]

Berberine protects against fructose-and-salt induced hypertensive renal injury. Mar 01, 2011

Pubmed Data : Zhong Yao Cai. 2011 Mar ;34(3):412-5. PMID: 21823461
Article Published Date : Mar 01, 2011
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Fructose-Induced Toxicity , Hypertension: Renal, Kidney Diseases
Pharmacological Actions : Renoprotective
Problem Substances : Fructose, Sodium Chloride
Adverse Pharmacological Actions : Nephrotoxic
[+]

Dietary fructose causes tubulointerstitial injury in the normal rat kidney.Mar 01, 2010

Pubmed Data : Am J Physiol Renal Physiol. 2010 Mar;298(3):F712-20. Epub 2010 Jan 13. PMID: 20071464
Article Published Date : Mar 01, 2010
Study Type : Animal Study
Additional Links
Diseases : Renal tubulointerstitial fibrosis
Problem Substances : Fructose
Adverse Pharmacological Actions : Nephrotoxic
[+]

Exposure to static magnetic fields induced oxidative stress in rat kidneys that can be prevented by treatment with selenium or vitamin E.Jan 01, 2015

Pubmed Data : Gen Physiol Biophys. 2015 Jan ;34(1):23-32. Epub 2014 Nov 14. PMID: 25395602
Article Published Date : Jan 01, 2015
Study Type : Animal Study
Additional Links
Substances : Selenium, Vitamin E
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation
Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation
Adverse Pharmacological Actions : Malondialdehyde (MDA) Up-Regulation, Nephrotoxic, Oxidant
[+]

Fenofibrate induce muscular toxicity in rats.Jan 01, 2009

Pubmed Data : Toxicol Pathol. 2009;37(4):517-20. Epub 2009 Apr 24. PMID: 19395589
Article Published Date : Jan 01, 2009
Study Type : Animal Study
Additional Links
Diseases : Myopathies
Problem Substances : Fenofibrates
Adverse Pharmacological Actions : Nephrotoxic
[+]

Fructose causes renal damage in an animal model of metabolic syndrome. May 01, 2011

Pubmed Data : Pediatr Nephrol. 2011 May 1. Epub 2011 May 1. PMID: 21533627
Article Published Date : May 01, 2011
Study Type : Animal Study
Additional Links
Diseases : Fructose-Induced Toxicity , Kidney Damage, Metabolic Syndrome X
Problem Substances : Fructose
Adverse Pharmacological Actions : Inflammatory, Nephrotoxic
[+]

Fructose induces nephropathy and hyperuricemia in rats. May 25, 2011

Pubmed Data : Planta Med. 2011 May 25. Epub 2011 May 25. PMID: 21614752
Article Published Date : May 25, 2011
Study Type : Animal Study
Additional Links
Diseases : Hyperuricemia, Nephropathy
Problem Substances : Fructose
Adverse Pharmacological Actions : Interleukin-1 up-regulation, Nephrotoxic, Prostaglandin E2 up-regulation
[+]

Fructose, but not dextrose, accelerates the progression of chronic kidney disease.Oct 01, 2007

Pubmed Data : Am J Physiol Renal Physiol. 2007 Oct;293(4):F1256-61. Epub 2007 Aug 1. PMID: 17670904
Article Published Date : Oct 01, 2007
Study Type : Animal Study
Additional Links
Diseases : Kidney Diseases
Problem Substances : Fructose
Adverse Pharmacological Actions : Nephrotoxic
[+]

Fructose-fed rats exhibit increased inflammation, fibrogenesis and NF-κB activation.Jun 17, 2011

Pubmed Data : Eur J Pharmacol. 2011 Jun 17. Epub 2011 Jun 17. PMID: 21704028
Article Published Date : Jun 17, 2011
Study Type : Animal Study
Additional Links
Diseases : Advanced Glycation End products (AGE), Inflammation, Kidney Damage, Kidney Diseases, Kidney Fibrosis
Problem Substances : Fructose
Adverse Pharmacological Actions : Inflammatory, Nephrotoxic, NF-kappaB up-regulation, Oxidant, Profibrotic
[+]

L-thyroxine increases oxidative stress in rat renal cortex.Feb 01, 2011

Pubmed Data : Mol Biol Rep. 2011 Feb;38(2):1047-54. Epub 2010 Jun 24. PMID: 20574713
Article Published Date : Feb 01, 2011
Study Type : Animal Study
Additional Links
Problem Substances : Thyroxine
Adverse Pharmacological Actions : Nephrotoxic
[+]

Melatonin and caffeic acid phenethyl ester prevent renal tubular injury by reducing oxidative stress and protect the kidney from oxidative damage induced by 900 MHz mobile phone.Aug 01, 2005

Pubmed Data : Mol Cell Biochem. 2005 Aug ;276(1-2):31-7. PMID: 16132682
Article Published Date : Aug 01, 2005
Study Type : Animal Study
Additional Links
Substances : Caffeic acid phenethyl ester, Melatonin
Diseases : Radiation Induced Illness
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation
Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation
Adverse Pharmacological Actions : Nephrotoxic
[+]

Mice administered thimerosal develop an age-dependent spontaneous systemic autoimmune disease with high mortality primarily due to immune-complex glomerulonephritis.Jul 01, 2006

Pubmed Data : Toxicol Appl Pharmacol. 2006 Jul 1 ;214(1):43-54. Epub 2006 Jan 27. PMID: 16443248
Article Published Date : Jul 01, 2006
Study Type : Animal Study
Additional Links
Diseases : Autoimmune Diseases
Additional Keywords : Autoimmunity, Vaccine Research
Problem Substances : Mercury, Thimerosal
Adverse Pharmacological Actions : Immunoreactive, Nephrotoxic
[+]

Olive leaf extract ameliorates gentamicin nephrotoxicity via antioxidant activity, increase of renal glutathione content, and increase of renal antioxidant enzymes activity, except for glutathione peroxidase.Jan 01, 2012

Pubmed Data : Iran J Kidney Dis. 2012 Jan ;6(1):25-32. PMID: 22218116
Article Published Date : Jan 01, 2012
Study Type : Animal Study
Additional Links
Substances : Olive leaf extract
Diseases : Chemotherapy-Induced Toxicity: Gentamicin
Pharmacological Actions : Antioxidants, Glutathione Upregulation , Renoprotective
Problem Substances : Gentamicin
Adverse Pharmacological Actions : Nephrotoxic, Oxidant
[+]

Sesame oil protects against cypermethrin-induced toxicity to rat liver and kidney.Jan 01, 2012

Pubmed Data : J Environ Sci Health B. 2012 ;47(4):306-14. PMID: 22428892
Article Published Date : Jan 01, 2012
Study Type : Animal Study
Additional Links
Substances : Sesame Seed Oil
Diseases : Chemically-Induced Liver Damage, Kidney Damage: Chemically-Induced, Pesticide Toxicity: Cypermethrin
Problem Substances : Cypermethrin
Adverse Pharmacological Actions : Hepatotoxic, Nephrotoxic
[+]

Sodium fluoride administered through drinking water exhibits liver and kidney toxicity in mice. Sep 22, 2010

Pubmed Data : Arch Toxicol. 2010 Sep 22. Epub 2010 Sep 22. PMID: 20859737
Article Published Date : Sep 22, 2010
Study Type : Animal Study
Additional Links
Problem Substances : Sodium Fluoride
Adverse Pharmacological Actions : Hepatotoxic, Nephrotoxic
[+]

Sodium hexametaphosphate is a skin irritant topically and has adverse kidney effects when ingested (10% diet) animal experiments..Jan 01, 2001

Pubmed Data : Int J Toxicol. 2001;20 Suppl 3:75-89. PMID: 11766135
Article Published Date : Jan 01, 2001
Study Type : Animal Study
Additional Links
Diseases : Dermatitis: Contact, Kidney Damage
Problem Substances : Sodium hexametaphosphate
Adverse Pharmacological Actions : Nephrotoxic
[+]

Spirulina platensis is a potent antioxidant that could ameliorate the effect of chromium induced nephrotoxicity and provided a near complete protection.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2015 ;10(6):e0126780. Epub 2015 Jun 1. PMID: 26029926
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Spirulina
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants, Renoprotective
Additional Keywords : Risk Reduction
Adverse Pharmacological Actions : Nephrotoxic
[+]

Sulforaphane prevents cell death and inflammation in nephropathy.Jun 16, 2011

Pubmed Data : J Nutr Biochem. 2011 Jun 16. Epub 2011 Jun 16. PMID: 21684138
Article Published Date : Jun 16, 2011
Study Type : Animal Study
Additional Links
Substances : Sulforaphane
Diseases : Chemotherapy-Induced Toxicity: Cisplatin, Nephropathy
Pharmacological Actions : Renoprotective
Problem Substances : Cisplatin
Adverse Pharmacological Actions : Nephrotoxic
[+]

The reduced form of coenzyme Q10 may prevent or minimize cyclosporine nephrotoxicity by an antioxidant effect.Nov 27, 2012

Pubmed Data : Exp Clin Transplant. 2012 Nov 28. Epub 2012 Nov 28. PMID: 23194328
Article Published Date : Nov 27, 2012
Study Type : Animal Study
Additional Links
Substances : Ubiquinol
Diseases : Nephropathy
Pharmacological Actions : Renoprotective
Problem Substances : Cyclosporine
Adverse Pharmacological Actions : Nephrotoxic
[+]

These findings suggest that GSM-like radiofrequency radiation interferes with gene expression during early gestation and results in aberrations of bone morphogenetic protein expression in the newborn.Apr 01, 2004

Pubmed Data : Bioelectromagnetics. 2004 Apr ;25(3):216-27. PMID: 15042631
Article Published Date : Apr 01, 2004
Study Type : Animal Study
Additional Links
Additional Keywords : Pregnancy, Pregnancy And Fetal Growth
Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation
Adverse Pharmacological Actions : Nephrotoxic
[+]

Uranium nitrate is renotoxic and dramatically alters the expression of more than 200 genes in the rat kidney. Nov 01, 2004

Pubmed Data : Environ Health Perspect. 2004 Nov;112(16):1628-35. PMID: 15598614
Article Published Date : Nov 01, 2004
Study Type : Animal Study
Additional Links
Diseases : Kidney Damage, Oxidative Stress, Uranium Poisoning
Problem Substances : Uranium
Adverse Pharmacological Actions : Genotoxic, Nephrotoxic
[+]

Aluminum is implicated in Alzheimer's, ALS, and parkinsonism-dementia. Its accumulation occurs primarily in infants and children with immature or impaired renal function.Jun 01, 1990

Pubmed Data : Clin Lab Med. 1990 Jun ;10(2):403-22. PMID: 2197055
Article Published Date : Jun 01, 1990
Study Type : Review
Additional Links
Diseases : Alzheimer's Disease, Amyotrophic lateral sclerosis (ALS), Kidney Failure: Chronic, Parkinson's Disease
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum
Adverse Pharmacological Actions : Bioaccumulator, Nephrotoxic, Neurotoxic
[+]

Clear toxicities of pollutants were observed cell lines at very low sub-agricultural dilutions.Jan 01, 2011

Pubmed Data : J Occup Med Toxicol. 2011;6(1):3. Epub 2011 Jan 20. PMID: 21251308
Article Published Date : Jan 01, 2011
Study Type : In Vitro Study
Additional Links
Diseases : Chemical Exposure, Chemically-Induced Liver Damage, Kidney Damage, Liver Damage
Problem Substances : Bisphenol A , Glyphosate
Adverse Pharmacological Actions : Hepatotoxic, Nephrotoxic
[+]

Glyphosate, hard water and nephrotoxic metals: are they the culprits behind the epidemic of chronic kidney disease of unknown etiology in sri lanka?Dec 31, 2013

Pubmed Data : Int J Environ Res Public Health. 2014 ;11(2):2125-47. Epub 2014 Feb 20. PMID: 24562182
Article Published Date : Dec 31, 2013
Study Type : Review
Additional Links
Diseases : Chronic Kidney Disease of Unknown Etiology (CKDu), Kidney Damage: Chemically-Induced, Kidney Diseases
Problem Substances : Glyphosate, Roundup (herbicide)
Adverse Pharmacological Actions : Nephrotoxic
[+]

Statin drugs have been linked to rhabdomyolysis, myositis and kidney failure. Oct 21, 2011

Pubmed Data : Curr Vasc Pharmacol. 2011 Oct 21. Epub 2011 Oct 21. PMID: 22022768
Article Published Date : Oct 21, 2011
Study Type : Review
Additional Links
Diseases : Kidney Damage: Drug-Induced, Kidney Failure, Myositis, Rhabdomyolysis, Statin-Induced Pathologies
Problem Substances : Statin Drugs
Adverse Pharmacological Actions : Myotoxicity, Nephrotoxic
[+]

Statin drugs induce cell death in mouse kidney cells.Oct 01, 1997

Pubmed Data : Kidney Int. 1997 Oct ;52(4):962-72. PMID: 9328935
Article Published Date : Oct 01, 1997
Study Type : In Vitro Study
Additional Links
Diseases : Kidney Damage, Statin-Induced Pathologies
Problem Substances : Statin Drugs
Adverse Pharmacological Actions : Apoptotic, Cytotoxic, Nephrotoxic

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