Obesogenic

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18 Problem Substances Researched for Obesogenic
NameACCKFocus
Bisphenol A 321Locked
Persistent organic pollutants (POPs)220Locked
Polychlorinated biphenyls (PCBs)220Locked
2,5-dichlorophenol (2,5-DCP)110Locked
Antibiotics110Locked
Pesticides110Locked
Thimerosal 110Locked
β-hexachlorocyclohexane (βHCH)110Locked
Monosodium Glutamate (MSG)36Locked
Phthalates23Locked
Artificial Sweeteners12Locked
Aspartame12Locked
Bisphenol S12Locked
Fructose12Locked
Soy12Locked
Cow Milk11Locked
Infant Formula11Locked
Infant Formula: Cow's Milk Based11Locked
20 Diseases Researched for Obesogenic
NameACCKFocus
Obesity1466Locked
Obesity: Childhood220Locked
Insulin Resistance416Locked
Prenatal Chemical Exposures212Locked
Bisphenol-A Toxicity110Locked
Infant Chemical Exposures110Locked
Obesity: Abdominal110Locked
Diabetes Mellitus: Type 235Locked
Bisphenol Toxicity23Locked
Abdominal Obesity (Midsection Fat)12Locked
Fatty Liver12Locked
Fetal Origin of Adult Disease12Locked
Fructose-Induced Toxicity 12Locked
High Fat Diet12Locked
Infant Nutrition12Locked
Inflammation12Locked
Overweight 12Locked
Oxidative Stress12Locked
Triglycerides: Elevated12Locked
Phthalate Toxicity 11Locked

View the Evidence:
31 Abstracts with Obesogenic Research

[+]

BPA is positively associated with generalized obesity, abdominal obesity, and insulin resistance in middle-aged and elderly Chinese adults.Nov 16, 2011

Pubmed Data : J Clin Endocrinol Metab. 2011 Nov 16. Epub 2011 Nov 16. PMID: 22090277
Article Published Date : Nov 16, 2011
Study Type : Human Study
Additional Links
Diseases : Bisphenol-A Toxicity, Insulin Resistance, Obesity, Obesity: Abdominal
Problem Substances : Bisphenol A
Adverse Pharmacological Actions : Endocrine Disruptor: Insulin Resistance, Obesogenic
[+]

Exposure to antibiotics during the first 6 months of life is associated with consistent increases in body mass from 10 to 38 months.Aug 20, 2012

Pubmed Data : Int J Obes (Lond). 2012 Aug 21. Epub 2012 Aug 21. PMID: 22907693
Article Published Date : Aug 20, 2012
Study Type : Human Study
Additional Links
Diseases : Infant Chemical Exposures, Obesity
Problem Substances : Antibiotics
Adverse Pharmacological Actions : Endocrine Disruptor, Obesogenic
[+]

Higher BPA exposure is associated with general and central obesity in the general adult population of the United States. Aug 01, 2011

Pubmed Data : Environ Res. 2011 Aug ;111(6):825-30. Epub 2011 Jun 14. PMID: 21676388
Article Published Date : Aug 01, 2011
Study Type : Human Study
Additional Links
Diseases : Obesity
Problem Substances : Bisphenol A
Adverse Pharmacological Actions : Obesogenic
[+]

Increased organic mercury exposure from Thimerosal-containing hepatitis B vaccines could lead to an increased risk of obesity diagnosis.Jun 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : N Am J Med Sci. 2016 Jul ;8(7):297-306. PMID: 27583238
Article Published Date : Jun 30, 2016
Study Type : Human Study
Additional Links
Diseases : Obesity
Additional Keywords : Risk Factors
Anti Therapeutic Actions : Vaccination: Hepatitis B
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Obesogenic
[+]

Persistent organic pollutants exhibit diabetogenic and obesogenic properties.Apr 01, 2011

Pubmed Data : Obesity (Silver Spring). 2011 Apr;19(4):709-14. Epub 2010 Jun 17. PMID: 20559302
Article Published Date : Apr 01, 2011
Study Type : Human Study
Additional Links
Problem Substances : Persistent organic pollutants (POPs), Polychlorinated biphenyls (PCBs), β-hexachlorocyclohexane (βHCH)
Adverse Pharmacological Actions : Diabetogenic, Obesogenic
[+]

Prenatal exposure to persistent organic pollutants and rapid weight gain and overweight in infancy.Aug 19, 2013

Pubmed Data : Obesity (Silver Spring). 2013 Aug 20. Epub 2013 Aug 20. PMID: 23963708
Article Published Date : Aug 19, 2013
Study Type : Human Study
Additional Links
Diseases : Obesity: Childhood, Prenatal Chemical Exposures
Problem Substances : Persistent organic pollutants (POPs), Polychlorinated biphenyls (PCBs)
Adverse Pharmacological Actions : Obesogenic
[+]

There is an association between urinary concentrations of dichlorophenol pesticides and obesity in children.Jan 01, 2011

Pubmed Data : Rev Environ Health. 2011 ;26(3):215-9. PMID: 22206198
Article Published Date : Jan 01, 2011
Study Type : Human Study
Additional Links
Diseases : Obesity, Obesity: Childhood
Problem Substances : 2,5-dichlorophenol (2,5-DCP), Pesticides
Adverse Pharmacological Actions : Obesogenic
[+]

These results suggest that BPA substitute chemicals are correlated with obesity in contemporary children.Aug 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Endocr Soc. 2019 Sep 1 ;3(9):1715-1726. Epub 2019 Jul 25. PMID: 31528831
Article Published Date : Aug 31, 2019
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity, Obesity
Additional Keywords : Increased Risk
Problem Substances : Bisphenol A
Adverse Pharmacological Actions : Obesogenic
[+]

Urinary bisphenol A concentrations and adiposity measures at age 7 years in a prospective birth cohort.Feb 26, 2020

Pubmed Data : Chemosphere. 2020 Feb 27 ;251:126340. Epub 2020 Feb 27. PMID: 32135373
Article Published Date : Feb 26, 2020
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity, Obesity
Additional Keywords : Risk Factors
Problem Substances : Bisphenol A
Adverse Pharmacological Actions : Obesogenic
[+]

Bisphenol A enhances adipogenic signaling pathways in human mesenchymal stem cells.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Genes Environ. 2020 ;42:13. Epub 2020 Mar 11. PMID: 32175033
Article Published Date : Dec 31, 2019
Study Type : Human In Vitro
Additional Links
Diseases : Bisphenol Toxicity, Obesity
Additional Keywords : Increased Risk
Problem Substances : Bisphenol A
Adverse Pharmacological Actions : Obesogenic
[+]

Aspartames break down product phenylalanine, can inhibit the protective effects of intestinal alkaline phosphatase.Nov 17, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Appl Physiol Nutr Metab. 2016 Nov 18:1-7. Epub 2016 Nov 18. PMID: 27997218
Article Published Date : Nov 17, 2016
Study Type : Animal Study
Additional Links
Diseases : Insulin Resistance, Obesity
Additional Keywords : Artificial Sweeteners, aspartame, Insulin Resistance, obesity, Risk Factors
Problem Substances : Artificial Sweeteners, Aspartame
Adverse Pharmacological Actions : Obesogenic
[+]

Astaxanthin prevents fructose-induced adverse changes in insulin signaling and inflammation in obese rats.Nov 17, 2011

Pubmed Data : Food Funct. 2011 Nov 17. Epub 2011 Nov 17. PMID: 22089895
Article Published Date : Nov 17, 2011
Study Type : Animal Study
Additional Links
Substances : Astaxanthin
Diseases : Fructose-Induced Toxicity , Inflammation, Insulin Resistance, Obesity, Oxidative Stress
Pharmacological Actions : Anti-Adipogenic, Anti-Inflammatory Agents, Insulin Sensitizers
Problem Substances : Fructose
Adverse Pharmacological Actions : Endocrine Disruptor: Insulin Resistance, Obesogenic
[+]

Bisphenol F has different effects on preadipocytes differentiation and weight gain in adult mice as compared with bisphenol A and S.Apr 04, 2019

Pubmed Data : Toxicology. 2019 Apr 5. Epub 2019 Apr 5. PMID: 30959087
Article Published Date : Apr 04, 2019
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity, Obesity
Additional Keywords : Risk Factors
Problem Substances : Bisphenol F, Bisphenol S
Adverse Pharmacological Actions : Obesogenic
[+]

Bisphenol S potentiated the obesity induced by a high fat diet.May 15, 2016

Pubmed Data : Toxicology. 2016 May 16 ;357-358:11-20. Epub 2016 May 27. PMID: 27241191
Article Published Date : May 15, 2016
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity, Fetal Origin of Adult Disease, High Fat Diet, Prenatal Chemical Exposures
Additional Keywords : Risk Factors
Problem Substances : Bisphenol S
Adverse Pharmacological Actions : Obesogenic
[+]

Bisphenol S promotes fat storage in multiple generations.Nov 30, 2021

Pubmed Data : Comp Biochem Physiol C Toxicol Pharmacol. 2021 Dec ;250:109175. Epub 2021 Aug 28. PMID: 34464736
Article Published Date : Nov 30, 2021
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity, Obesity
Additional Keywords : Transgenerational inheritance
Problem Substances : Bisphenol A
Adverse Pharmacological Actions : Obesogenic
[+]

Dietary monosodium glutamate increases weight gain and adiposity, and reduces insulin sensitivity in an animal model.Mar 24, 2011

Pubmed Data : Br J Nutr. 2011 Mar 24:1-10. Epub 2011 Mar 24. PMID: 21429276
Article Published Date : Mar 24, 2011
Study Type : Animal Study
Additional Links
Diseases : Abdominal Obesity (Midsection Fat), Diabetes Mellitus: Type 2, Insulin Resistance, Obesity, Overweight
Problem Substances : Monosodium Glutamate (MSG)
Adverse Pharmacological Actions : Obesogenic
[+]

Exposure to DEHP reduces the hydrolysis of lipid and promotes triglyceride accumulation.Nov 03, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Environ Res Public Health. 2016 Nov 4 ;13(11). Epub 2016 Aug 4. PMID: 27827939
Article Published Date : Nov 03, 2016
Study Type : Animal Study
Additional Links
Diseases : Obesity, Triglycerides: Elevated
Additional Keywords : Risk Factors
Problem Substances : Phthalates
Adverse Pharmacological Actions : Obesogenic
[+]

Monosodium glutamate is used to induce obesity and fatty liver in an animal model. Apr 11, 2011

Pubmed Data : Metabolism. 2011 Apr 11. Epub 2011 Apr 11. PMID: 21489575
Article Published Date : Apr 11, 2011
Study Type : Animal Study
Additional Links
Diseases : Fatty Liver, Obesity
Problem Substances : Monosodium Glutamate (MSG)
Adverse Pharmacological Actions : Obesogenic
[+]

Neonatal monosodium glutamate intoxication is associated with obesity in the adult stage. Jun 01, 2011

Pubmed Data : Basic Clin Pharmacol Toxicol. 2011 Jun;108(6):406-13. Epub 2011 Feb 9. PMID: 21205225
Article Published Date : Jun 01, 2011
Study Type : Animal Study
Additional Links
Diseases : Infant Nutrition, Obesity
Problem Substances : Monosodium Glutamate (MSG)
Adverse Pharmacological Actions : Obesogenic
[+]

Obesogen effect of bisphenol S alters mRNA expression and DNA methylation profiling in male mouse liver.Oct 14, 2019

Pubmed Data : Chemosphere. 2019 Oct 15 ;241:125092. Epub 2019 Oct 15. PMID: 31683443
Article Published Date : Oct 14, 2019
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity, Chemically-Induced Liver Damage
Additional Keywords : DNA Methylation
Problem Substances : Bisphenol S
Adverse Pharmacological Actions : Obesogenic
[+]

Obesogenic effect of Bisphenol P on mice via altering the metabolic pathways.Mar 14, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ecotoxicol Environ Saf. 2023 Mar 15 ;253:114703. Epub 2023 Feb 28. PMID: 36857923
Article Published Date : Mar 14, 2023
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity, Obesity
Problem Substances : Bisphenol P
Adverse Pharmacological Actions : Obesogenic
[+]

Peroxisome proliferator-activated receptor gamma activation and metabolism disturbance induced by bisphenol A and bisphenol S.Nov 24, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Int. 2019 Nov 25 ;134:105328. Epub 2019 Nov 25. PMID: 31778932
Article Published Date : Nov 24, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity, Obesity
Problem Substances : Bisphenol A , Bisphenol S
Adverse Pharmacological Actions : Obesogenic
[+]

Prediabetic changes in gene expression induced by aspartame and monosodium glutamate in Trans fat-fed C57Bl/6 J mice.Dec 31, 1969

Study Type : Animal Study
Additional Links
Diseases : Abdominal Obesity (Midsection Fat), Diabetes, Obesity, Overweight
Problem Substances : Aspartame, Monosodium Glutamate (MSG)
Adverse Pharmacological Actions : Diabetogenic, Obesogenic
[+]

These results indicate that in mice a diet high in soybean oil is more detrimental to metabolic health than a diet high in fructose or coconut oil.Dec 31, 2014

Pubmed Data : PLoS One. 2015;10(7):e0132672. Epub 2015 Jul 22. PMID: 26200659
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Soybean Oil
Diseases : Diabetes Mellitus: Type 2, Obesity
Additional Keywords : Increased Risk
Problem Substances : Soy
Adverse Pharmacological Actions : Diabetogenic, Obesogenic
[+]

Bisphenol A analogues in food and their hormonal and obesogenic effects.Sep 05, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2019 Sep 6 ;11(9). Epub 2019 Sep 6. PMID: 31500194
Article Published Date : Sep 05, 2019
Study Type : Review
Additional Links
Diseases : Bisphenol Toxicity, Obesity
Problem Substances : Bisphenol A
Adverse Pharmacological Actions : Obesogenic
[+]

Bisphenol A analogues present a greater obesogenic capacity in 3T3-L1 cell line.May 31, 2020

Pubmed Data : Food Chem Toxicol. 2020 Jun ;140:111298. Epub 2020 Mar 24. PMID: 32220626
Article Published Date : May 31, 2020
Study Type : In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity
Problem Substances : Bisphenol A , Bisphenol F, Bisphenol S
Adverse Pharmacological Actions : Obesogenic
[+]

Bisphenol S in food causes hormonal and obesogenic effects comparable to or worse than bisphenol A.Feb 18, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2020 Feb 19 ;12(2). Epub 2020 Feb 19. PMID: 32092919
Article Published Date : Feb 18, 2020
Study Type : Review
Additional Links
Diseases : Bisphenol Toxicity
Problem Substances : Bisphenol A , Bisphenol S
Adverse Pharmacological Actions : Obesogenic
[+]

Cow milk-based infant formula may contribute to childhood obesity through excessive leucine-mTORC1-signalling.Jan 01, 2012

Pubmed Data : J Obes. 2012 ;2012:197653. Epub 2012 Mar 19. PMID: 22523661
Article Published Date : Jan 01, 2012
Study Type : Review
Additional Links
Diseases : Obesity
Problem Substances : Cow Milk, Infant Formula, Infant Formula: Cow's Milk Based
Adverse Pharmacological Actions : Obesogenic
[+]

Low-dose bisphenol-A promotes epigenetic changes at Pparγ promoter in adipose precursor cells.Nov 12, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2020 Nov 13 ;12(11). Epub 2020 Nov 13. PMID: 33203037
Article Published Date : Nov 12, 2020
Study Type : In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity, Obesity
Additional Keywords : Epigenetic Modification
Problem Substances : Bisphenol A
Adverse Pharmacological Actions : Obesogenic
[+]

The mixture of bisphenol-A and its substitutes bisphenol-S and bisphenol-F exerts obesogenic activity.May 26, 2022

Pubmed Data : Toxics. 2022 May 27 ;10(6). Epub 2022 May 27. PMID: 35736896
Article Published Date : May 26, 2022
Study Type : In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity, Obesity
Additional Keywords : Risk Factors
Problem Substances : Bisphenol A , Bisphenol F, Bisphenol S
Adverse Pharmacological Actions : Obesogenic
[+]

These endocrine disrupting chemicals interfere with different cell signalling pathways involved in weight and glucose homeostasis.Nov 06, 2016

Pubmed Data : Endocrine. 2016 Nov 7. Epub 2016 Aug 7. PMID: 27822670
Article Published Date : Nov 06, 2016
Study Type : Review
Additional Links
Diseases : Bisphenol Toxicity, Diabetes Mellitus: Type 2, Obesity, Phthalate Toxicity
Problem Substances : Bisphenol A , Phthalates
Adverse Pharmacological Actions : Diabetogenic, Obesogenic

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