Tumor necrosis factorα (TNFα) up-regulation

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8 Problem Substances Researched for Tumor necrosis factorα (TNFα) up-regulation
NameACCKFocus
Chemotherapy120Locked
Trans Fatty Acids110Locked
Cell Phone Exposure15Locked
Fructose12Locked
Simvastatin12Locked
Statin Drugs12Locked
Phthalates11Locked
Sodium Fluoride11Locked
25 Diseases Researched for Tumor necrosis factorα (TNFα) up-regulation
NameACCKFocus
Inflammation326Locked
Chemotherapy-Induced Toxicity120Locked
Depression120Locked
Fatigue120Locked
Insomnia120Locked
Vaccine-induced Toxicity 220Locked
Arthritis: Juvenile Idiopathic110Locked
CRP110Locked
Elevated CRP110Locked
Experimental Lung Inflammation110Locked
Pre-Eclampsia110Locked
Pregnancy Complications110Locked
Pregnancy: Vaccination110Locked
Preterm Birth: Prevention 110Locked
Brain: Microglial Activation15Locked
Chemically-Induced Liver Damage23Locked
Brain Inflammation 12Locked
DNA damage12Locked
Fructose-Induced Toxicity 12Locked
Liver Stress: Fructose-Induced12Locked
Myopathy12Locked
Nonalcoholic fatty liver disease (NAFLD)12Locked
Oxidative Stress12Locked
Statin-Induced Pathologies12Locked
Fluoride Toxicity 11Locked

View the Evidence:
11 Abstracts with Tumor necrosis factorα (TNFα) up-regulation Research

[+]

There are high rates of behavioral symptoms in breast cancer survivors, particularly those treated with chemotherapyAug 08, 2011

Pubmed Data : J Clin Oncol. 2011 Aug 8. Epub 2011 Aug 8. PMID: 21825266
Article Published Date : Aug 08, 2011
Study Type : Meta Analysis
Additional Links
Diseases : Chemotherapy-Induced Toxicity, Depression, Fatigue, Inflammation, Insomnia
Anti Therapeutic Actions : Chemotherapy
Problem Substances : Chemotherapy
Adverse Pharmacological Actions : Inflammatory, Tumor necrosis factorα (TNFα) up-regulation
[+]

Flu vaccination causes measurable increases in inflammation in pregnant women which may increase the risk of preeclempsia and adverse outcomes such as preterm birth. Sep 20, 2011

Pubmed Data : Vaccine. 2011 Sep 20. Epub 2011 Sep 20. PMID: 21945263
Article Published Date : Sep 20, 2011
Study Type : Human Study
Additional Links
Diseases : CRP, Elevated CRP, Pre-Eclampsia, Pregnancy: Vaccination, Pregnancy Complications, Preterm Birth: Prevention , Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: All, Vaccination: Influenza
Adverse Pharmacological Actions : Interleukin-6 up-regulation, Tumor necrosis factorα (TNFα) up-regulation
[+]

Industrially produced trans fatty acids increase tumor necrosis factor, an indicator of systemic inflammation. Jul 27, 2011

Pubmed Data : J Lipid Res. 2011 Jul 27. Epub 2011 Jul 27. PMID: 21795740
Article Published Date : Jul 27, 2011
Study Type : Human Study
Additional Links
Diseases : Experimental Lung Inflammation
Problem Substances : Trans Fatty Acids
Adverse Pharmacological Actions : Inflammatory, Tumor necrosis factorα (TNFα) up-regulation
[+]

Thirty-five percent of children with juvenile idiopathic arthritis experienced flare of the disease after vaccination. Mar 15, 2012

Pubmed Data : Clin Exp Rheumatol. 2012 Mar 15. Epub 2012 Mar 15. PMID: 22513085
Article Published Date : Mar 15, 2012
Study Type : Human Study
Additional Links
Diseases : Arthritis: Juvenile Idiopathic, Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: All, Vaccination: Influenza
Adverse Pharmacological Actions : Tumor necrosis factorα (TNFα) up-regulation
[+]

1800 MHz radiofrequency fields stimulates pro-inflammatory responses in microglia and astrocytes in vitro.Jan 01, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2014 ;9(9):e108318. Epub 2014 Oct 2. PMID: 25275372
Article Published Date : Jan 01, 2014
Study Type : Human In Vitro
Additional Links
Diseases : Brain: Microglial Activation, Inflammation
Additional Keywords : Brain Function, Brain Inflammation, Cell Phones, electromagnetic fields, electromagnetic frequencies, electromagnetic radiation, EMF
Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation, Electromagnetic Radiation: 1.8 GHz, Microwave Radiation, Mobile Phone Radiation
Problem Substances : Cell Phone Exposure
Adverse Pharmacological Actions : Cycloogenase-2 enzyme upregulation, Inflammatory, Interleukin-1 up-regulation, Interleukin-6 up-regulation, Prostaglandin E2 up-regulation, Tumor necrosis factorα (TNFα) up-regulation
[+]

Simvastatin altered gene targets known to be implicated in proteasomal and lysosomal mediated muscle proteolysis, carbohydrate oxidation, oxidative stress and inflammation.Jan 14, 2009

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Physiol. 2009 Jan 15 ;587(Pt 1):219-30. Epub 2008 Nov 10. PMID: 19001041
Article Published Date : Jan 14, 2009
Study Type : Animal Study
Additional Links
Diseases : Myopathy, Statin-Induced Pathologies
Additional Keywords : Gene Expression
Problem Substances : Simvastatin, Statin Drugs
Adverse Pharmacological Actions : Inflammatory, Interleukin-6 up-regulation, Tumor necrosis factorα (TNFα) up-regulation
[+]

This rat model shows tht individual maternal immune response to maternal immune activation is an important determinant of the behavioral outcome in offspring.Nov 01, 2014

Pubmed Data : Brain Behav Immun. 2014 Nov ;42:138-46. Epub 2014 Jun 26. PMID: 24973728
Article Published Date : Nov 01, 2014
Study Type : Animal Study
Additional Links
Additional Keywords : Pregnancy, Pregnancy And Fetal Growth, Vaccine Research
Adverse Pharmacological Actions : Tumor necrosis factorα (TNFα) up-regulation
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This study demonstrates the pro-inflammatory, pro-oxidant, and genotoxic effects of microwave radiation in rat brains.Dec 01, 2015

Pubmed Data : Neurotoxicology. 2015 Dec ;51:158-65. Epub 2015 Oct 25. PMID: 26511840
Article Published Date : Dec 01, 2015
Study Type : Animal Study
Additional Links
Diseases : Brain Inflammation , DNA damage, Oxidative Stress
Anti Therapeutic Actions : Microwave Radiation
Adverse Pharmacological Actions : Glutathione Down-Regulation, Inflammatory, Interleukin-6 up-regulation, Malondialdehyde (MDA) Up-Regulation, Oxidant, Tumor necrosis factorα (TNFα) up-regulation
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Tumor necrosis factorα (TNFα) plays a role in the onset of fructose-induced nonalcoholic fatty liver disease in mice.Jun 01, 2011

Pubmed Data : J Nutr Biochem. 2011 Jun;22(6):527-34. Epub 2010 Aug 30. PMID: 20801629
Article Published Date : Jun 01, 2011
Study Type : Animal Study
Additional Links
Diseases : Chemically-Induced Liver Damage, Fructose-Induced Toxicity , Liver Stress: Fructose-Induced, Nonalcoholic fatty liver disease (NAFLD)
Problem Substances : Fructose
Adverse Pharmacological Actions : Hepatotoxic, Tumor necrosis factorα (TNFα) up-regulation
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Expression of SDF-1/CXCR4 and related inflammatory factors in sodium fluoride-treated hepatocytes.Dec 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2024 ;19(6):e0302530. Epub 2024 Jun 21. PMID: 38905184
Article Published Date : Dec 31, 2023
Study Type : In Vitro Study
Additional Links
Diseases : Chemically-Induced Liver Damage, Fluoride Toxicity , Inflammation
Problem Substances : Sodium Fluoride
Adverse Pharmacological Actions : Interleukin-1 up-regulation, Interleukin-6 up-regulation, Tumor necrosis factorα (TNFα) up-regulation
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Results from this review have suggested that at least one phthalate has the ability to enhance tumour necrosis factor-α production from monocytes and macrophages.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2015 ;10(3):e0120083. Epub 2015 Mar 26. PMID: 25811352
Article Published Date : Dec 31, 2014
Study Type : Review
Additional Links
Additional Keywords : Cytokines, Problem Substance Synergy
Problem Substances : Phthalates
Adverse Pharmacological Actions : Tumor necrosis factorα (TNFα) up-regulation

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