Abortion: Spontaneous

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25 Problem Substances Researched for Abortion: Spontaneous
NameACCKFocus
Coffee340Locked
Caffeine330Locked
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)220Locked
Anaesthetic Gases110Locked
Antibiotics110Locked
Celecoxib110Locked
Diclofenac110Locked
Fluoride110Locked
Gliadin110Locked
Ibuprofen110Locked
Lead110Locked
Naproxen110Locked
Pesticides110Locked
Photoresist and developed solvents (PDS)110Locked
Pivmecillinam110Locked
Radiation Exposure110Locked
Rofecoxib110Locked
Tea110Locked
Tobacco Smoke: Passive110Locked
Triclosan110Locked
Wheat110Locked
Lovastatin15Locked
Letrozole (trade name Femera)12Locked
Statin Drugs12Locked
Gluten11Locked
4 Problematic Actions Researched for Abortion: Spontaneous
NameACCKFocus
Dilation and Curettage (D&C)431Locked
Obstetric Interventions431Locked
Vaccination: All713Locked
Vaccination: Animal Model612Locked

View the Evidence:
42 Abstracts with Abortion: Spontaneous Research

[+]

Consumption of coffee during pregnancy was associated with a higher risk of fetal death, especially losses occurring after 20 completed weeks of gestation.Nov 15, 2005

Pubmed Data : Am J Epidemiol. 2005 Nov 15;162(10):983-90. Epub 2005 Oct 5. PMID: 16207803
Article Published Date : Nov 15, 2005
Study Type : Meta Analysis
Additional Links
Diseases : Abortion: Spontaneous, Fetal Death, Miscarriage
Problem Substances : Coffee
Adverse Pharmacological Actions : Teratogenic
[+]

11.4% of adverse events reported to VAERS following the inactivated influenza vaccine in pregnant women were spontaneous abortions.Jan 01, 2017

Pubmed Data : Drug Saf. 2017 02 ;40(2):145-152. PMID: 27988883
Article Published Date : Jan 01, 2017
Study Type : Human Study
Additional Links
Diseases : Abortion: Spontaneous
Anti Therapeutic Actions : Vaccination: All, Vaccination: Influenza
[+]

37.6% of the women subjected to curettage following abortion had intra-uterine adhesions.Sep 06, 2007

Pubmed Data : Sao Paulo Med J. 2007 Sep 6;125(5):261-4. PMID: 18094891
Article Published Date : Sep 06, 2007
Study Type : Human Study
Additional Links
Diseases : Abortion: Induced, Abortion: Spontaneous, Intra-Uterine Adhesions, Miscarriage
Anti Therapeutic Actions : Dilation and Curettage (D&C), Obstetric Interventions
[+]

Among women with distant HPV vaccine exposure, 10.4% experienced spontaneous abortion. For peri-pregnancy and during pregnancy exposures, spontaneous abortions occurred in 11.2% and 8.6%, respectively.Jan 01, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Obstet Gynecol. 2018 07 ;132(1):35-44. PMID: 29889760
Article Published Date : Jan 01, 2018
Study Type : Human Study
Additional Links
Diseases : Abortion: Spontaneous, Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: All, Vaccination: HPV (Gardasil)
[+]

An increased risk of spontaneous abortion among fabrication workers has been linked to fluoride compound and photoresist and developed solvents (PDS) exposure. Nov 30, 1995

Pubmed Data : Am J Ind Med. 1995 Dec ;28(6):751-69. PMID: 8588562
Article Published Date : Nov 30, 1995
Study Type : Human Study
Additional Links
Diseases : Abortion: Spontaneous, Infertility: Female
Problem Substances : Fluoride, Photoresist and developed solvents (PDS)
Adverse Pharmacological Actions : Abortive, Anti-Fertility
[+]

Association of bisphenol A or bisphenol S exposure with oxidative stress and immune disturbance among unexplained recurrent spontaneous abortion women.Sep 30, 2020

Pubmed Data : Chemosphere. 2020 Oct ;257:127035. Epub 2020 May 14. PMID: 32702804
Article Published Date : Sep 30, 2020
Study Type : Human Study
Additional Links
Diseases : Abortion: Spontaneous, Bisphenol Toxicity
Additional Keywords : Risk Factors
Problem Substances : Bisphenol A , Bisphenol S
[+]

Celiac disease associated antibodies are higher in Argentine women with recurrent pregnancy loss.Mar 01, 2006

Pubmed Data : Am J Reprod Immunol. 2006 Mar;55(3):201-7. PMID: 16451354
Article Published Date : Mar 01, 2006
Study Type : Human Study
Additional Links
Diseases : Abortion: Spontaneous, Miscarriage: Recurrent
Problem Substances : Gliadin, Wheat
Adverse Pharmacological Actions : Teratogenic
[+]

Coffee drinking early in pregnancy is associated with an increased risk of abortion.Aug 01, 1998

Pubmed Data : Hum Reprod. 1998 Aug;13(8):2286-91. PMID: 9756312
Article Published Date : Aug 01, 1998
Study Type : Human Study
Additional Links
Diseases : Abortion: Spontaneous, Miscarriage
Problem Substances : Coffee
Adverse Pharmacological Actions : Teratogenic
[+]

Environmental tobacco smoke increases the risk of spontaneous abortion.Sep 01, 2006

Pubmed Data : Epidemiology. 2006 Sep;17(5):500-5. PMID: 16837826
Article Published Date : Sep 01, 2006
Study Type : Human Study
Additional Links
Diseases : Abortion: Spontaneous, Miscarriage
Problem Substances : Tobacco Smoke: Passive
Adverse Pharmacological Actions : Teratogenic
[+]

Heavy caffeine consumption (especially when there is nausea) during pregnancy may increase the risk of spontaneous abortion.May 01, 1991

Pubmed Data : Epidemiology. 1991 May;2(3):168-74. PMID: 2054397
Article Published Date : May 01, 1991
Study Type : Human Study
Additional Links
Diseases : Abortion: Spontaneous, Miscarriage
Problem Substances : Caffeine
Adverse Pharmacological Actions : Teratogenic
[+]

Low to moderate lead exposures may increase the risk for spontaneous abortion at exposures comparable to US general population levels.Sep 15, 1999

Pubmed Data : Am J Epidemiol. 1999 Sep 15;150(6):590-7. PMID: 10489998
Article Published Date : Sep 15, 1999
Study Type : Human Study
Additional Links
Diseases : Abortion: Spontaneous, Miscarriage
Problem Substances : Lead
[+]

Maternal caffeine consumption is associated with an increased risk of spontaneous abortion.May 01, 1996

Pubmed Data : Epidemiology. 1996 May;7(3):250-5. PMID: 8728437
Article Published Date : May 01, 1996
Study Type : Human Study
Additional Links
Diseases : Abortion: Spontaneous, Miscarriage
Problem Substances : Caffeine, Coffee, Tea
Adverse Pharmacological Actions : Teratogenic
[+]

Maternal exposure to occupational hazards associated with radiation, pesticides and anesthetic gases (e.g. veterinary practice) is associated with an increased risk of spontaneous abortions.Nov 01, 2008

Pubmed Data : Occup Environ Med. 2008 Nov;65(11):719-25. Epub 2008 Apr 3. PMID: 18388114
Article Published Date : Nov 01, 2008
Study Type : Human Study
Additional Links
Diseases : Abortion: Spontaneous, Miscarriage
Problem Substances : Anaesthetic Gases, Pesticides, Radiation Exposure
Adverse Pharmacological Actions : Teratogenic
[+]

Mobile phone use during pregnancy may be related to spontaneous abortion.Jan 01, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Environ Health Sci Eng. 2015 ;13:34. Epub 2015 Apr 21. PMID: 25937931
Article Published Date : Jan 01, 2015
Study Type : Human Study
Additional Links
Diseases : Abortion: Spontaneous, Pregnancy Complications
Additional Keywords : Cell Phones, electromagnetic fields, electromagnetic frequencies, electromagnetic radiation, EMF, Pregnancy, Pregnancy And Fetal Growth, Radio Frequency Electromagnetic Radiation Exposure
Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation, Microwave Radiation, Mobile Phone Radiation
Problem Substances : Cell Phone Exposure
Adverse Pharmacological Actions : Abortive
[+]

Post-abortion intra-uterine adhesions occur frequently. Mar 01, 1993

Pubmed Data : Hum Reprod. 1993 Mar;8(3):442-4. PMID: 8473464
Article Published Date : Mar 01, 1993
Study Type : Human Study
Additional Links
Diseases : Abortion: Induced, Abortion: Spontaneous, Intra-Uterine Adhesions, Miscarriage, Miscarriage: Medical Intervention
Anti Therapeutic Actions : Dilation and Curettage (D&C), Obstetric Interventions
[+]

Recurrent miscarriage may be associated with autoimmunity.Jan 01, 1996

Pubmed Data : Eur J Endocrinol. 1996 Jan;134(1):84-6. PMID: 8590962
Article Published Date : Jan 01, 1996
Study Type : Human Study
Additional Links
Diseases : Abortion: Spontaneous, Autoimmune Diseases, Autoimmune Thyroiditis, Miscarriage: Recurrent
Additional Keywords : Diseases that are Linked
[+]

Taking non-aspirin NSAIDs in early pregnancy doubles the risk of miscarriage. Jan 01, 2011

Pubmed Data : BMJ. 2011 ;343:d5769. Epub 2011 Sep 9. PMID: 21908536
Article Published Date : Jan 01, 2011
Study Type : Human Study
Additional Links
Diseases : Abortion: Spontaneous, Drug-Induced Toxicity , Miscarriage
Pharmacological Actions : Teratogens
Problem Substances : Celecoxib, Diclofenac, Ibuprofen, Naproxen, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), Rofecoxib
Adverse Pharmacological Actions : Teratogenic
[+]

The available evidence suggests that medical treatment, with misoprostol, and expectant care are both acceptable alternatives to routine surgical evacuation for incomplete miscarriage (less than 24 months). Jan 01, 2010

Pubmed Data : Cochrane Database Syst Rev. 2010(1):CD007223. Epub 2010 Jan 20. PMID: 20091626
Article Published Date : Jan 01, 2010
Study Type : Human Study
Additional Links
Diseases : Abortion: Spontaneous, Miscarriage, Miscarriage: Medical Intervention
Additional Keywords : Surgical Alternatives
Anti Therapeutic Actions : Dilation and Curettage (D&C), Obstetric Interventions
[+]

The ingestion of caffeine may increase the risk of an early spontaneous abortion among non-smoking women carrying fetuses with normal karyotypes.Dec 21, 2000

Pubmed Data : N Engl J Med. 2000 Dec 21;343(25):1839-45. PMID: 11117975
Article Published Date : Dec 21, 2000
Study Type : Human Study
Additional Links
Diseases : Abortion: Spontaneous, Miscarriage
Problem Substances : Caffeine
Adverse Pharmacological Actions : Teratogenic
[+]

The most commonly reported adverse event associated with the hepatitis A vaccine in pregnant women was spontaneous abortion.Jun 01, 2014

Pubmed Data : Am J Obstet Gynecol. 2014 Jun ;210(6):561.e1-6. Epub 2013 Dec 27. PMID: 24378675
Article Published Date : Jun 01, 2014
Study Type : Human Study
Additional Links
Diseases : Abortion: Spontaneous
Anti Therapeutic Actions : Vaccination: All
[+]

The most frequently reported adverse event in pregnant women who received the Tdap vaccine was spontaneous abortion.Jul 01, 2012

Pubmed Data : Am J Obstet Gynecol. 2012 Jul ;207(1):59.e1-7. Epub 2012 May 14. PMID: 22727350
Article Published Date : Jul 01, 2012
Study Type : Human Study
Additional Links
Diseases : Abortion: Spontaneous, Vaccine-induced Toxicity
Additional Keywords : Pregnancy, Pregnancy And Fetal Growth, Vaccine Research
Anti Therapeutic Actions : Vaccination: Diphtheria-Pertussis-Tetanus
Adverse Pharmacological Actions : Abortive
[+]

The use of certain antibiotics during early pregnancy was associated with an increased risk of spontaneous abortion.Apr 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : CMAJ. 2017 May 1 ;189(17):E625-E633. PMID: 28461374
Article Published Date : Apr 30, 2017
Study Type : Human Study
Additional Links
Diseases : Abortion: Spontaneous, Antibiotic Toxicity
Additional Keywords : Increased Risk
Problem Substances : Antibiotics
[+]

There may be an inflammatory component to pathologic pregnancies, as evidenced by a Th1-dominant profile in women whose pregnancies ended in spontaneous abortion.Oct 01, 1996

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Exp Immunol. 1996 Oct ;106(1):127-33. PMID: 8870710
Article Published Date : Oct 01, 1996
Study Type : Human Study
Additional Links
Diseases : Abortion: Spontaneous, Female, Pregnancy Complications
Adverse Pharmacological Actions : Immunoreactive, Immunotoxic
[+]

These findings indicate that triclosan exposure might cause spontaneous abortion.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2015 ;5:18252. Epub 2015 Dec 15. PMID: 26666354
Article Published Date : Dec 31, 2014
Study Type : Animal Study, Human Study
Additional Links
Diseases : Abortion: Spontaneous, Miscarriage
Additional Keywords : Risk Factors
Problem Substances : Triclosan
Adverse Pharmacological Actions : Abortive
[+]

This study provides some evidence that women vaccinated with yellow fever vaccine during early pregnancy have an increased risk of spontaneous abortion.Jan 01, 1998

Pubmed Data : Trop Med Int Health. 1998 Jan ;3(1):29-33. PMID: 9484965
Article Published Date : Jan 01, 1998
Study Type : Human Study
Additional Links
Diseases : Abortion: Spontaneous
Anti Therapeutic Actions : Vaccination: All, Vaccination: Yellow Fever
[+]

Use of non-steroidal anti-inflammatory drugs during pregnancy is associated with increased risk of miscarriage.Feb 03, 2001

Pubmed Data : BMJ. 2001 Feb 3;322(7281):266-70. PMID: 11157526
Article Published Date : Feb 03, 2001
Study Type : Human Study
Additional Links
Diseases : Abortion: Spontaneous, Miscarriage
Problem Substances : Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
Adverse Pharmacological Actions : Teratogenic
[+]

Use of pivmecillinam (antibiotic) is associated with an increased risk of miscarriage.Apr 01, 2008

Pubmed Data : APMIS. 2008 Apr;116(4):278-83. PMID: 18397462
Article Published Date : Apr 01, 2008
Study Type : Human Study
Additional Links
Diseases : Abortion: Spontaneous, Female Urogenital Diseases and Pregnancy Complications, Miscarriage, Pregnancy Complications, Pregnancy Complications: Urinary Tract Infections, Prenatal Chemical Exposures
Additional Keywords : Antibiotic Use in Pregnancy
Problem Substances : Antibiotics, Pivmecillinam
Adverse Pharmacological Actions : Teratogenic
[+]

Vitamin D3 leads to decreased serum levels of IL-23 and incidence of abortion among women with unexplained recurrent spontaneous abortion.Jul 11, 2016

Pubmed Data : Glob J Health Sci. 2016 Jul 12 ;9(3):57723. Epub 2016 Aug 12. PMID: 27806501
Article Published Date : Jul 11, 2016
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Abortion: Spontaneous, Vitamin D Deficiency
Pharmacological Actions : Interleukin-23 Downregulation
Additional Keywords : Risk Factors, Risk Reduction
[+]

Women who received the H1N1 vaccine in the previous had a 7.7-fold higher risk of spontaneous abortion in the 28 days following a subsequent flu vaccine.Jan 25, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Vaccine. 2017 09 25 ;35(40):5314-5322. PMID: 28917295
Article Published Date : Jan 25, 2017
Study Type : Human Study
Additional Links
Diseases : Abortion: Spontaneous
Anti Therapeutic Actions : Vaccination: All, Vaccination: Influenza
[+]

Lovastatin exhibits toxicity in human fetal brain cells.Jan 01, 1995

Pubmed Data : Neurotoxicol Teratol. 1995 Jan-Feb;17(1):31-9. PMID: 7708017
Article Published Date : Jan 01, 1995
Study Type : Human In Vitro
Additional Links
Diseases : Abortion: Spontaneous, Birth Defects, Neurotoxicity, Prenatal Chemical Exposures
Pharmacological Actions : Antiproliferative
Problem Substances : Lovastatin
Adverse Pharmacological Actions : Neurotoxic, Teratogenic
[+]

A vaccine developed for bison resulted in inducing placentitis and abortion in pregnant cows.Nov 01, 1996

Pubmed Data : Am J Vet Res. 1996 Nov;57(11):1604-7. PMID: 8915438
Article Published Date : Nov 01, 1996
Study Type : Animal Study
Additional Links
Diseases : Abortion: Spontaneous, Animal Diseases: Infectious , Vaccination: Abortion, Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: All, Vaccination: Animal Model
[+]

Letrozole has a toxic effect on the embryos of rats. Nov 01, 2009

Pubmed Data : Hum Reprod. 2009 Nov;24(11):2688-92. Epub 2009 Jul 27. PMID: 19638353
Article Published Date : Nov 01, 2009
Study Type : Animal Study
Additional Links
Diseases : Abortion: Spontaneous, Birth Defects, Prenatal Chemical Exposures
Problem Substances : Letrozole (trade name Femera)
Adverse Pharmacological Actions : Embryotoxic, Teratogenic
[+]

Pregnant cows vaccinated against a Brucella strain experienced an abortion rate of 58%. Apr 01, 1991

Pubmed Data : J Wildl Dis. 1991 Apr;27(2):258-64. PMID: 1906114
Article Published Date : Apr 01, 1991
Study Type : Animal Study
Additional Links
Diseases : Abortion: Spontaneous, Animal Diseases: Infectious , Vaccination: Abortion, Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: All, Vaccination: Animal Model
[+]

Pregnant cows vaccinated with live attenuated Smithburn Rift Valley virus had a high rate of abortions which were associated with elevations in IgG and IgM antibodies.Jun 01, 2006

Pubmed Data : J Med Virol. 2006 Jun;78(6):787-91. PMID: 16628582
Article Published Date : Jun 01, 2006
Study Type : Animal Study
Additional Links
Diseases : Abortion: Spontaneous, Animal Diseases: Smithburn Rift Valley Fever, Vaccination: Abortion, Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: All, Vaccination: Animal Model
[+]

Rift Valley fever vaccine in goats cause severe deleterious pathological changes in liver especially in kids and causing abortion in pregnant does.Jan 01, 2009

Pubmed Data : Virol J. 2009;6:94. Epub 2009 Jul 6. PMID: 19580675
Article Published Date : Jan 01, 2009
Study Type : Animal Study
Additional Links
Diseases : Abortion: Spontaneous, Animal Diseases: Smithburn Rift Valley Fever, Rift Valley Fever, Vaccination: Abortion, Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: All, Vaccination: Animal Model
[+]

Statin drugs have been shown to cause adverse effects in pregnant rats and their offspring, including fetal death. Oct 17, 2011

Pubmed Data : Birth Defects Res B Dev Reprod Toxicol. 2011 Oct 17. Epub 2011 Oct 17. PMID: 22006546
Article Published Date : Oct 17, 2011
Study Type : Animal Study
Additional Links
Diseases : Abortion: Spontaneous, Birth Defects, Statin-Induced Pathologies
Problem Substances : Statin Drugs
Adverse Pharmacological Actions : Teratogenic
[+]

The vaccination of pregnant sheep resulted in abortions and hydranencephaly.Mar 01, 2005

Pubmed Data : Int Immunopharmacol. 2005 Mar;5(3):555-69. PMID: 8825310
Article Published Date : Mar 01, 2005
Study Type : Animal Study
Additional Links
Diseases : Abortion: Spontaneous, Hydranencephaly, Vaccination: Abortion, Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: All, Vaccination: Animal Model
[+]

Vaccination of pregnant monkeys resulted in abortions in 2 out of 25.Apr 01, 1991

Pubmed Data : Am J Trop Med Hyg. 1991 Apr;44(4):382-9. PMID: 2042705
Article Published Date : Apr 01, 1991
Study Type : Animal Study
Additional Links
Diseases : Abortion: Spontaneous, Animal Diseases: Infectious , Vaccination: Abortion, Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: All, Vaccination: Animal Model
[+]

Anti-inflammatory effects of gallic acid in human gestational tissues in vitro.Jan 09, 2020

Pubmed Data : Reproduction. 2020 10 ;160(4):561-578. PMID: 32698152
Article Published Date : Jan 09, 2020
Study Type : In Vitro Study
Additional Links
Substances : Gallic Acid
Diseases : Abortion: Spontaneous, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Recurrent miscarriages may be due to undiagnosed celiac disease.Feb 01, 2000

Pubmed Data : Recenti Prog Med. 2000 Feb;91(2):72-5. PMID: 10748651
Article Published Date : Feb 01, 2000
Study Type : Review
Additional Links
Diseases : Abortion: Spontaneous, Celiac Disease, Miscarriage, Miscarriage: Recurrent
Problem Substances : Gluten
Adverse Pharmacological Actions : Teratogenic
[+]

The number of elective abortions following vaccination during pregnancy may be under-reported and could be substantial.May 02, 2008

Pubmed Data : Vaccine. 2008 May 2;26(19):2428-32. Epub 2008 Mar 17. PMID: 18406499
Article Published Date : May 02, 2008
Study Type : Review
Additional Links
Diseases : Abortion: Spontaneous, Vaccination: Abortion, Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: All
[+]

There is a significant lack of information from large-scale studies about when treatment is necessary and the relative efficacy, rates of side effects, and acceptability of these various treatment options for early pregnancy failure.Feb 01, 2001

Pubmed Data : Obstet Gynecol Surv. 2001 Feb;56(2):105-13. PMID: 11219590
Article Published Date : Feb 01, 2001
Study Type : Review
Additional Links
Diseases : Abortion: Spontaneous, Miscarriage: Medical Intervention
Anti Therapeutic Actions : Dilation and Curettage (D&C), Obstetric Interventions

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